X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (44224) 44224
Publication (7061) 7061
Book Chapter (157) 157
Book Review (152) 152
Book / eBook (90) 90
Conference Proceeding (63) 63
Dissertation (33) 33
Newsletter (17) 17
Magazine Article (12) 12
Data Set (7) 7
Web Resource (3) 3
Government Document (2) 2
Reference (2) 2
Journal / eJournal (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (30613) 30613
animals (23657) 23657
index medicus (22691) 22691
mice (16347) 16347
female (11657) 11657
male (10509) 10509
oncology (9967) 9967
apoptosis (9140) 9140
immunology (8999) 8999
cell biology (8816) 8816
expression (8287) 8287
cancer (8158) 8158
signal transduction (7657) 7657
proteins (6775) 6775
phosphorylation (6499) 6499
gene expression (6105) 6105
multidisciplinary sciences (6104) 6104
biochemistry & molecular biology (6002) 6002
activation (5966) 5966
cell line, tumor (5942) 5942
research article (5881) 5881
research (5235) 5235
proto-oncogene proteins c-akt - metabolism (5154) 5154
medicine (5078) 5078
middle aged (5041) 5041
proto-oncogene proteins - metabolism (4964) 4964
cells, cultured (4940) 4940
cell line (4751) 4751
mutation (4749) 4749
adult (4740) 4740
science (4655) 4655
proto-oncogene proteins - genetics (4626) 4626
kinases (4367) 4367
mice, inbred c57bl (4277) 4277
article (4209) 4209
genetic aspects (4151) 4151
hematology (4066) 4066
tumors (4034) 4034
analysis (3893) 3893
aged (3796) 3796
apoptosis - drug effects (3552) 3552
immunohistochemistry (3517) 3517
rats (3500) 3500
cell proliferation (3370) 3370
cells (3363) 3363
proto-oncogene proteins c-bcl-2 - metabolism (3321) 3321
molecular sequence data (3288) 3288
biology (3077) 3077
rodents (2998) 2998
genes (2828) 2828
mice, knockout (2828) 2828
pathology (2824) 2824
signal transduction - drug effects (2776) 2776
health aspects (2768) 2768
gene (2716) 2716
physiological aspects (2669) 2669
protein (2632) 2632
medicine, research & experimental (2586) 2586
blotting, western (2527) 2527
cell cycle (2522) 2522
differentiation (2519) 2519
gene-expression (2476) 2476
tumor cells, cultured (2475) 2475
oncogenes (2417) 2417
gene expression regulation, neoplastic (2406) 2406
transfection (2391) 2391
phosphatidylinositol 3-kinases - metabolism (2390) 2390
base sequence (2383) 2383
inhibition (2359) 2359
in-vivo (2344) 2344
biochemistry (2338) 2338
flow cytometry (2320) 2320
transcription factors (2301) 2301
survival (2294) 2294
amino acid sequence (2270) 2270
mice, transgenic (2206) 2206
prognosis (2195) 2195
gene expression regulation (2170) 2170
inflammation (2133) 2133
protein binding (2106) 2106
leukemia (2096) 2096
proto-oncogene proteins c-bcl-2 - genetics (2039) 2039
cell differentiation (1986) 1986
akt protein (1974) 1974
mice, inbred balb c (1967) 1967
growth (1963) 1963
metastasis (1945) 1945
reverse transcriptase polymerase chain reaction (1937) 1937
nf-kappa-b (1928) 1928
dna-binding proteins - metabolism (1911) 1911
dna-binding proteins - genetics (1904) 1904
stem cells (1898) 1898
dna (1878) 1878
genetics (1846) 1846
proliferation (1845) 1845
signaling (1844) 1844
rna, messenger - genetics (1821) 1821
care and treatment (1817) 1817
cell proliferation - drug effects (1808) 1808
disease models, animal (1791) 1791
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (65) 65
UofT at Mississauga - Stacks (7) 7
Online Resources - Online (4) 4
UTL at Downsview - May be requested (4) 4
Collection Dvlpm't (Acquisitions) - Vendor file (3) 3
St. Michael's Hospital - Circulation Desk (2) 2
St. Michael's Hospital - Stacks (2) 2
Collection Dvlpm't (Acquisitions) - Closed Orders (1) 1
Gerstein Science - Bindery (1) 1
Gerstein Science - Circulation Desk (1) 1
Gerstein Science - Periodical Stacks (1) 1
Providence Healthcare - Withdrawn (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (1) 1
UofT at Scarborough - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (43876) 43876
Chinese (286) 286
Japanese (98) 98
Russian (36) 36
French (35) 35
German (18) 18
Spanish (16) 16
Polish (10) 10
Hungarian (8) 8
Romanian (8) 8
Italian (5) 5
Czech (4) 4
Portuguese (3) 3
Swedish (3) 3
Ukrainian (3) 3
Korean (1) 1
Norwegian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Immunologic Research, ISSN 0257-277X, 10/2011, Volume 51, Issue 1, pp. 45 - 60
Complement system activation plays an important role in both innate and acquired immunity. Activation of the complement and the subsequent formation of C5b-9... 
Allergology | Signal transduction | Immunology | Medicine & Public Health | Cell cycle | Internal Medicine | Membrane attack complex | C5b-9 terminal complement complex | Transcriptional regulation | Medicine/Public Health, general | Apoptosis | ACTIVATED PROTEIN-KINASE | SYSTEMIC LUPUS-ERYTHEMATOSUS | GUILLAIN-BARRE-SYNDROME | ULCERATIVE-COLITIS | GLOMERULAR EPITHELIAL-CELLS | C5B-9 COMPLEX | IMMUNOLOGY | S-PROTEIN | MANNAN-BINDING LECTIN | ACUTE MYOCARDIAL-INFARCTION | SMOOTH-MUSCLE-CELLS | Forkhead Transcription Factors - immunology | CDC2 Protein Kinase | Complement Membrane Attack Complex - metabolism | Cyclin-Dependent Kinase 4 - genetics | Humans | Caspase 8 - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Complement Membrane Attack Complex - immunology | MAP Kinase Signaling System - immunology | Phosphatidylinositol 3-Kinases - immunology | Cell Cycle Proteins - immunology | Cyclin B - immunology | Forkhead Transcription Factors - metabolism | Muscle Proteins - metabolism | bcl-Associated Death Protein - metabolism | Cell Membrane - metabolism | Phosphorylation - immunology | Cyclin-Dependent Kinases | Proto-Oncogene Proteins c-akt - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Cyclin-Dependent Kinase 2 - metabolism | Mitogen-Activated Protein Kinase 3 - immunology | Muscle Proteins - immunology | G1 Phase - immunology | S Phase - immunology | Nerve Tissue Proteins - immunology | Cell Cycle Proteins - metabolism | bcl-Associated Death Protein - immunology | Cyclin-Dependent Kinase 4 - metabolism | Nerve Tissue Proteins - metabolism | Caspase 8 - immunology | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-akt - immunology | Mitogen-Activated Protein Kinase 3 - metabolism | BH3 Interacting Domain Death Agonist Protein - immunology | Cyclin B - metabolism | Cell Membrane - immunology | Forkhead Box Protein O1 | Cyclin-Dependent Kinase 2 - immunology | Medical colleges | Membranes | Immune system | apoptosis | membrane attack complex | cell cycle | signal transduction | transcriptional regulation
Journal Article
Nature Immunology, ISSN 1529-2908, 08/2010, Volume 11, Issue 8, pp. 734 - 742
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 02/2013, Volume 210, Issue 2, pp. 269 - 285
Acquisition of self-tolerance in the thymus requires T cells to discriminate strong versus weak T cell receptor binding by self-peptide-MHC complexes. We find... 
DEVELOPING THYMOCYTES | MEDICINE, RESEARCH & EXPERIMENTAL | TISSUE-RESTRICTED ANTIGENS | SELF-PEPTIDE | RECEPTOR TRANSGENIC MICE | IN-VIVO | BIM | NEGATIVE SELECTION | C-MYC | CLONAL DELETION | IMMUNOLOGY | EXPRESSION | Autoimmunity | Cell Proliferation | NF-kappa B - immunology | Proto-Oncogene Proteins c-rel - metabolism | Proto-Oncogene Proteins - biosynthesis | Proto-Oncogene Proteins c-rel - immunology | CARD Signaling Adaptor Proteins - genetics | CD4-Positive T-Lymphocytes - immunology | Membrane Proteins - deficiency | CARD Signaling Adaptor Proteins - metabolism | Bcl-2-Like Protein 11 | Receptors, CCR7 - metabolism | Apoptosis Regulatory Proteins - deficiency | Programmed Cell Death 1 Receptor - biosynthesis | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | Transcription Factors - immunology | Apoptosis Regulatory Proteins - biosynthesis | CARD Signaling Adaptor Proteins - immunology | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Lymphocyte Activation | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Self Tolerance | Membrane Proteins - immunology | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Transcription Factors - biosynthesis | Proto-Oncogene Proteins - deficiency | Clonal Deletion - immunology | Mice, Knockout | Membrane Proteins - biosynthesis | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-rel - genetics | NF-kappa B - biosynthesis | Mice | Mutation | Programmed Cell Death 1 Receptor - immunology | DNA-Binding Proteins - biosynthesis | 309
Journal Article
Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 514 - 527
Interleukin-21 (IL-21) has broad actions on T and B cells, but its actions in innate immunity are poorly understood. Here we show that IL-21 induced apoptosis... 
NKT CELLS | HOMEOSTASIS | FOLLICULAR-HELPER-CELLS | HUMAN B-CELLS | STEADY-STATE | INTERLEUKIN-21 | DIFFERENTIATION | IMMUNOLOGY | IMMUNE TOLERANCE | T-CELLS | NEGATIVE REGULATOR | Natural Killer T-Cells - drug effects | Oligonucleotide Array Sequence Analysis | Apoptosis - drug effects | Dendritic Cells - immunology | STAT5 Transcription Factor - immunology | Receptors, Interleukin-21 - genetics | Interferon-gamma - metabolism | CD4-Positive T-Lymphocytes - immunology | Interleukins - genetics | Gene Expression - immunology | STAT3 Transcription Factor - genetics | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | DNA, Intergenic - genetics | Protein Binding - immunology | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Galactosylceramides - immunology | Mice | STAT3 Transcription Factor - immunology | Gene Expression - drug effects | Galactosylceramides - pharmacology | DNA-Binding Proteins - deficiency | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Receptors, Interleukin-21 - deficiency | Flow Cytometry | Bcl-2-Like Protein 11 | Natural Killer T-Cells - metabolism | DNA, Intergenic - metabolism | Interleukins - immunology | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | Dendritic Cells - drug effects | Membrane Proteins - metabolism | Interleukins - pharmacology | Dendritic Cells - metabolism | STAT3 Transcription Factor - metabolism | Proto-Oncogene Proteins - metabolism | Receptors, Interleukin-21 - immunology | Mice, Inbred C57BL | Cells, Cultured | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Membrane Proteins - immunology | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Animals | Apoptosis - immunology | Interferon-gamma - immunology | CD4-Positive T-Lymphocytes - drug effects | DNA, Intergenic - immunology | Natural Killer T-Cells - immunology | Interleukins | Dendritic cells | Analysis | Genomics | Macrophage colony stimulating factor | Biological response modifiers | T cells | Apoptosis | Cytokines | Genes | Genomes | Kinases | Binding sites | Deoxyribonucleic acid--DNA | apoptosis | dendritic cells | GM-CSF | IL-21
Journal Article
Immunity, ISSN 1074-7613, 04/2015, Volume 42, Issue 4, pp. 613 - 626
Epigenetic regulation of lineage-specific genes is important for the differentiation and function of T cells. Ten-eleven translocation (Tet) proteins catalyze... 
METHYLATION | INTERLEUKIN-27 | TRANSCRIPTION | DISEASE | POPULATIONS | PATTERNS | GENERATION | DIFFERENTIATION | SPECIFICATION | IMMUNOLOGY | PLASTICITY | Cytosine - analogs & derivatives | 5-Methylcytosine - analogs & derivatives | E1A-Associated p300 Protein - immunology | Humans | E1A-Associated p300 Protein - genetics | T-Box Domain Proteins - immunology | Th1 Cells - immunology | DNA Methylation | Cytosine - metabolism | Proto-Oncogene Proteins - immunology | Th17 Cells - cytology | Cell Differentiation | STAT4 Transcription Factor - immunology | Cytokines - immunology | Cytosine - immunology | DNA-Binding Proteins - immunology | Th17 Cells - enzymology | DNA - immunology | Gene Expression Regulation | Mice, Transgenic | Proto-Oncogene Proteins - genetics | DNA - metabolism | DNA-Binding Proteins - genetics | T-Box Domain Proteins - genetics | Animals | Epigenesis, Genetic - immunology | Th17 Cells - immunology | STAT4 Transcription Factor - genetics | Th1 Cells - enzymology | Mice | Th1 Cells - cytology | Genome | Cytokines - biosynthesis | Proteins | Epigenetic inheritance | Cytokines | Genes | Genomics | DNA | Genetic research | Genomes | Ophthalmology | T cells | Gene expression | Cell differentiation | Transcription factors | Lymphocytes | Rodents | DNA methylation | Epigenetics | Genetic testing | Experiments | Binding sites | Deoxyribonucleic acid--DNA
Journal Article
Immunity, ISSN 1074-7613, 09/2015, Volume 43, Issue 3, pp. 475 - 487
Interleukin-17 (IL-17) induces pathology in autoimmunity and infections; therefore, constraint of this pathway is an essential component of its regulation. We... 
negative regulation | Regnase-1 | fungal immunity | autoimmunity | signal transduction | IL-17 | Autoimmunity | Signal transduction | Fungal immunity | Negative regulation | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | IL-17 RECEPTOR | TARGET GENES | CANDIDA-ALBICANS | C/EBP-BETA | GENE-EXPRESSION | HOST-DEFENSE | NECROSIS-FACTOR-ALPHA | MESSENGER-RNA STABILITY | T-CELL | IMMUNOLOGY | Candidiasis - genetics | Oncogene Proteins - genetics | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Immunoblotting | Male | Receptors, Interleukin-17 - genetics | Ribonucleases - metabolism | Host-Pathogen Interactions - immunology | Inflammation - metabolism | Lipocalins - genetics | Adaptor Proteins, Signal Transducing - immunology | Pneumonia - immunology | Candida albicans - physiology | Encephalomyelitis, Autoimmune, Experimental - genetics | Receptors, Interleukin-17 - metabolism | Interleukin-6 - metabolism | Pneumonia - genetics | Interleukin-6 - genetics | Oncogene Proteins - metabolism | Signal Transduction - genetics | Candida albicans - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Interleukin-17 - metabolism | Lipocalin-2 | Lipocalins - immunology | Interleukin-6 - immunology | Pneumonia - metabolism | Ribonucleases - genetics | Encephalomyelitis, Autoimmune, Experimental - metabolism | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Acute-Phase Proteins - genetics | Candidiasis - microbiology | Signal Transduction - immunology | HEK293 Cells | Female | Candidiasis - immunology | Nuclear Proteins - genetics | Oncogene Proteins - immunology | Lipocalins - metabolism | Cell Line | Acute-Phase Proteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Nuclear Proteins - metabolism | Inflammation - immunology | Nuclear Proteins - immunology | Animals | Ribonucleases - immunology | Adaptor Proteins, Signal Transducing - genetics | Inflammation - genetics | Adaptor Proteins, Signal Transducing - metabolism | Acute-Phase Proteins - immunology | Medical colleges | Nucleases | Interleukins | RNA | Cellular signal transduction | Inflammation | Proteins | Cytokines | Rodents | Fibroblasts | Infections | Kinases | Laboratory animals | Gene expression | Experiments
Journal Article
Nature Immunology, ISSN 1529-2908, 03/2015, Volume 16, Issue 4, pp. 354 - 365
Interleukin 37 (IL-37) and IL-1R8 (SIGIRR or TIR8) are anti-inflammatory orphan members of the IL-1 ligand family and IL-1 receptor family, respectively. Here... 
CELLS | FAMILY-MEMBER | INFLAMMATION | TIR8/SIGIRR | INFECTION | IMMUNOLOGY | TOLL | INHIBITOR | EXPRESSION | NEGATIVE REGULATOR | MOLECULES | Inflammation - pathology | Interleukin-1 - genetics | RNA, Small Interfering - genetics | RNA-Binding Proteins - genetics | Humans | Receptors, Interleukin-1 - genetics | NF-kappa B - immunology | Receptor Protein-Tyrosine Kinases - immunology | Proto-Oncogene Proteins c-fyn - genetics | Signal Transduction - immunology | TOR Serine-Threonine Kinases - genetics | PTEN Phosphohydrolase - immunology | RNA, Small Interfering - immunology | Receptors, Interleukin-1 - deficiency | Leukocytes, Mononuclear - immunology | c-Mer Tyrosine Kinase | Interleukin-1 - immunology | Interleukin-18 Receptor alpha Subunit - genetics | Proto-Oncogene Proteins - immunology | Proto-Oncogene Proteins c-fyn - immunology | STAT3 Transcription Factor - genetics | Cell Line | PTEN Phosphohydrolase - genetics | Interleukin-18 Receptor alpha Subunit - immunology | Leukocytes, Mononuclear - drug effects | MAP Kinase Kinase Kinases - genetics | Receptors, Interleukin-1 - immunology | RNA-Binding Proteins - immunology | Gene Expression Regulation | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Inflammation - immunology | Immunity, Innate | MAP Kinase Kinase Kinases - immunology | Interleukin-18 Receptor alpha Subunit - antagonists & inhibitors | Leukocytes, Mononuclear - pathology | TOR Serine-Threonine Kinases - immunology | Animals | NF-kappa B - genetics | Receptor Protein-Tyrosine Kinases - genetics | Lipopolysaccharides - pharmacology | Inflammation - genetics | Protein Binding | Mice | STAT3 Transcription Factor - immunology | Receptors, Interleukin-1 - antagonists & inhibitors
Journal Article
Immunity, ISSN 1074-7613, 03/2012, Volume 36, Issue 3, pp. 401 - 414
Journal Article
Nature immunology, ISSN 1529-2908, 2009, Volume 10, Issue 10, pp. 1081 - U58
Journal Article