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1. Full Text Going viral with cancer immunotherapy
by Lichty, Brian D and Breitbach, Caroline J and Stojdl, David F and Bell, John C
Nature Reviews Cancer, ISSN 1474-175X, 2014, Volume 14, Issue 8, pp. 559 - 567
Recent clinical data have emphatically shown the capacity of our immune systems to eradicate even advanced cancers. Although oncolytic viruses (OVs) were... 
PHASE-III TRIAL | HERPES-SIMPLEX-VIRUS | RECOMBINANT VACCINIA VIRUS | TARGETED ONCOLYTIC POXVIRUS | CLINICAL-TRIAL | ONCOLOGY | GM-CSF | NEWCASTLE-DISEASE VIRUS | T-CELLS | TUMOR-ANTIGEN | ESTABLISHED TUMORS | Immunologic Factors | Genetic Vectors - immunology | Immunotherapy, Adoptive | Humans | Oncolytic Viruses - genetics | Genetic Vectors - genetics | Oncolytic Virotherapy | Cancer Vaccines - genetics | Cancer Vaccines - immunology | Neoplasms - therapy | Animals | Neoplasms - genetics | Neoplasms - immunology | Immunotherapy | Oncolytic Viruses - immunology | Virus diseases | Usage | Care and treatment | Patient outcomes | Genetic aspects | Research | Risk factors | Methods | Cancer
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2. Full Text Oncolytic virotherapy
by Russell, Stephen J and Peng, Kah-Whye and Bell, John C
Nature Biotechnology, ISSN 1087-0156, 07/2012, Volume 30, Issue 7, pp. 658 - 670
Oncolytic virotherapy is an emerging treatment modality that uses replication-competent viruses to destroy cancers. Recent advances include preclinical proof... 
TUMOR-SPECIFIC DEFECTS | MEDIATED GENE-EXPRESSION | HERPES-SIMPLEX-VIRUS | INTRATUMORAL SPREAD | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | NONLINEAR DOSE-RESPONSE | MEASLES-VIRUS | VESICULAR STOMATITIS-VIRUS | PHASE-I | MESENCHYMAL STEM-CELLS | T-CELLS | Neoplasms - therapy | Humans | Simplexvirus - genetics | Adenoviridae - genetics | Oncolytic Viruses - genetics | Clinical Trials as Topic | Genetic Vectors | Immunity, Cellular | Oncolytic Virotherapy | Biotechnology | Oncology | Viruses | Propagation | Cancer therapies
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3. Full Text History of Oncolytic Viruses: Genesis to Genetic Engineering
by Kelly, Elizabeth and Russell, Stephen J
Molecular Therapy, ISSN 1525-0016, 04/2007, Volume 15, Issue 4, pp. 651 - 659
Since the turn of the nineteenth century, when their existence was first recognized, viruses have attracted considerable interest as possible agents of tumor... 
Neoplasms - therapy | Animals | History, 21st Century | Virology - history | History, 20th Century | Humans | History, 19th Century | Oncolytic Viruses - genetics | Genetic Engineering - history | Oncolytic Virotherapy - history
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4. Full Text Cancer-fighting viruses win approval
by Ledford, Heidi
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7575, pp. 622 - 623
MULTIDISCIPLINARY SCIENCES | United States | Humans | Oncolytic Viruses - genetics | United States Food and Drug Administration - legislation & jurisprudence | Oncolytic Virotherapy - methods | Genetic Engineering | Melanoma - immunology | Immunotherapy | Oncolytic Viruses - immunology | Herpesviridae - genetics | Survival Analysis | Herpesviridae - immunology | Melanoma - therapy
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5. Full Text Oncolytic virus therapy: A new era of cancer treatment at dawn
by Fukuhara, Hiroshi and Ino, Yasushi and Todo, Tomoki
Cancer Science, ISSN 1347-9032, 10/2016, Volume 107, Issue 10, pp. 1373 - 1379
Oncolytic virus therapy is perhaps the next major breakthrough in cancer treatment following the success in immunotherapy using immune checkpoint inhibitors.... 
herpes simplex virus | Clinical trial | oncolytic immunotherapy | G47 | oncolytic virus | COLONY-STIMULATING FACTOR | CLINICAL-TRIAL | ANTIGEN PRESENTATION | HERPES-SIMPLEX-VIRUS | LAHERPAREPVEC T-VEC | ONCOLOGY | PHASE-I TRIAL | GM-CSF | REOVIRUS INFECTION | ANTITUMOR IMMUNITY | INVASIVE BLADDER-CANCER | Immunotherapy - methods | Genetic Vectors - administration & dosage | Humans | Oncolytic Viruses - genetics | Treatment Outcome | Clinical Trials as Topic | Genetic Vectors - genetics | Immunotherapy - adverse effects | Oncolytic Virotherapy - methods | Neoplasms - therapy | Animals | Genetic Engineering | Neoplasms - genetics | Oncolytic Virotherapy - adverse effects | Genetic Therapy - adverse effects | Genetic Therapy - methods | Oncology, Experimental | Immunotherapy | Genetically modified organisms | Melanoma | Genetic engineering | Research | Drug therapy | Health aspects | Drug approval | Cancer | Brain cancer | Genes | Glioblastoma | Clinical trials | Herpes simplex | Hepatocellular carcinoma | Viruses | Genomes | Cancer therapies | Tropical diseases | Hepatitis | Oncolysis | Cytokines | Research & development--R&D | Bladder cancer | Patients | Fever | Immune checkpoint | Adenoviruses | Head and neck cancer | Head & neck cancer | Viral infections | Tumors | Review
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6. Full Text Artificial riboswitches for gene expression and replication control of DNA and RNA viruses
by Patrick Ketzer and Johanna K. Kaufmann and Sarah Engelhardt and Sascha Bossow and Christof von Kalle and Jörg S. Hartig and Guy Ungerechts and Dirk M. Nettelbeck
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 02/2014, Volume 111, Issue 5, pp. E554 - E562
Aptazymes are small, ligand-dependent self-cleaving ribozymes that function independently of transcription factors and can be customized for induction by... 
RIBOZYMES | REGULATORY SYSTEMS | INHIBITION | THERAPY | MULTIDISCIPLINARY SCIENCES | IN-VIVO | TRANSCRIPTION | ATTENUATION | INTERFERENCE | MEASLES-VIRUS | ADENOVIRUS | RNA Viruses - pathogenicity | Virus Replication - genetics | RNA, Catalytic - metabolism | RNA Viruses - physiology | Adenoviridae - pathogenicity | DNA Viruses - genetics | Virus Internalization | Measles virus - genetics | Riboswitch - genetics | Adenovirus E1A Proteins - metabolism | Genes, Viral - genetics | Adenoviridae - genetics | DNA Viruses - physiology | Measles virus - pathogenicity | Cell Line | DNA Viruses - pathogenicity | Virion - physiology | RNA Viruses - genetics | Adenoviridae - physiology | Oncolytic Viruses - genetics | Gene Expression Regulation, Viral | Adenovirus E1A Proteins - genetics | Oncolytic Viruses - physiology | Ligands | Measles virus - physiology | PNAS Plus | Biological Sciences
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7. Full Text Maraba Virus as a Potent Oncolytic Vaccine Vector
by Pol, Jonathan G and Zhang, Liang and Bridle, Byram W and Stephenson, Kyle B and Rességuier, Julien and Hanson, Stephen and Chen, Lan and Kazdhan, Natasha and Bramson, Jonathan L and Stojdl, David F and Wan, Yonghong and Lichty, Brian D
Molecular Therapy, ISSN 1525-0016, 02/2014, Volume 22, Issue 2, pp. 420 - 429
The rhabdovirus Maraba has recently been characterized as a potent oncolytic virus. In the present study, we engineered an attenuated Maraba strain, defined as... 
MEDICINE, RESEARCH & EXPERIMENTAL | CLINICAL-TRIAL | ADENOVIRAL VECTORS | PHASE I/II | CANCER | THERAPY | IMMUNOTHERAPY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DNA | GENETICS & HEREDITY | REOVIRUS | CARCINOEMBRYONIC ANTIGEN | ANTITUMOR IMMUNITY | Lung Neoplasms - mortality | Cytopathogenic Effect, Viral | Vesiculovirus - immunology | Neoplasms - therapy | Lung Neoplasms - secondary | Melanoma, Experimental | Neoplasms - genetics | Vesiculovirus - genetics | Female | Viral Tropism | Lung Neoplasms - genetics | Gene Expression | Genetic Vectors - immunology | Neoplasms - mortality | Immunization, Secondary - methods | Oncolytic Viruses - genetics | Treatment Outcome | Lung Neoplasms - therapy | Genetic Vectors - genetics | Cancer Vaccines - immunology | Lung Neoplasms - immunology | Animals | Intramolecular Oxidoreductases - genetics | Neoplasms - immunology | Rhabdoviridae - immunology | Oncolytic Viruses - immunology | Mice | Rhabdoviridae - genetics | CD8-Positive T-Lymphocytes - immunology | Neoplasms - pathology | Original
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8. Full Text Engineering targeted viral vectors for gene therapy
by Waehler, Reinhard and Curiel, David T and Russell, Stephen J
Nature Reviews Genetics, ISSN 1471-0056, 08/2007, Volume 8, Issue 8, pp. 573 - 587
To achieve therapeutic success, transfer vehicles for gene therapy must be capable of transducing target cells while avoiding impact on non-target cells.... 
DEPENDENT ADENOVIRAL VECTORS | IN-VIVO | GENETICS & HEREDITY | SINGLE-CHAIN ANTIBODY | MURINE LEUKEMIA-VIRUS | VASCULAR ENDOTHELIAL-CELLS | OVARIAN-CANCER | HUMAN-IMMUNODEFICIENCY-VIRUS | PRESENTING PHAGE LIBRARIES | RETROVIRAL VECTOR | ONCOLYTIC MEASLES VIRUSES | Genetic Engineering - methods | Animals | Transduction, Genetic | Viruses - genetics | Humans | Ligands | Models, Genetic | Genetic Therapy - trends | Genetic Vectors | In Vitro Techniques | Genetic Engineering - trends | Genetic Therapy - methods | Usage | Cancer cells | Physiological aspects | Genetic engineering | Genetic aspects | Research | Gene therapy | Health aspects | Methods
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9. Full Text New viruses for cancer therapy: Meeting clinical needs
by Miest, Tanner S and Cattaneo, Roberto
Nature Reviews Microbiology, ISSN 1740-1526, 01/2014, Volume 12, Issue 1, pp. 23 - 34
Early-stage clinical trials of oncolytic virotherapy have reported the safety of several virus platforms, and viruses from three families have progressed to... 
HERPES-SIMPLEX-VIRUS | HEPATOCELLULAR-CARCINOMA | MICRORNA REGULATION | IODIDE SYMPORTER NIS | PHASE-I TRIAL | SUICIDE GENE | CYTOSINE DEAMINASE | MICROBIOLOGY | INTRATUMORAL INJECTION | CARCINOEMBRYONIC ANTIGEN | ONCOLYTIC MEASLES-VIRUS | Viruses - classification | Oncolytic Virotherapy - methods | Neoplasms - therapy | Animals | Genetic Engineering | Viruses - genetics | Humans | Disease Models, Animal
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