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Methods in Molecular Biology, ISSN 1064-3745, 2015, Volume 1248, pp. 223 - 237
Combinatorial one-bead-one-compound (OBOC) peptide library screening has proven to be a powerful tool for identification of small molecules, peptides, or... 
Split-and-pool synthesis | One-bead-one-compound | On-bead cell-binding assay | COPAS biosorter | Particle sorter | Cell Line, Tumor | Animals | Peptide Library | Humans | High-Throughput Screening Assays - methods
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2015, Volume 1248, pp. 39 - 53
Cyclic peptides have been a rich source of biologically active molecules. Herein we present a method for the combinatorial synthesis and screening of large... 
High-throughput screening | Cyclic peptide | Protein-protein interaction | One-bead-one-compound library | Peptides, Cyclic - chemical synthesis | Peptides, Cyclic - chemistry | Peptide Library
Journal Article
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 1/2009, Volume 36, Issue 1, pp. 94 - 103
Patients with glioblastoma usually have a very poor prognosis. Even with a combination of radiotherapy plus temozolomide, the median survival of these patients... 
Molecular imaging | Small animal imaging | Glioblastoma | Combinatorial chemistry | Oncology | Optical imaging | Integrin | Medicine & Public Health | Orthopedics | Cancer targeting | One-bead one-compound peptide library | Nuclear Medicine | Cardiology | Imaging / Radiology | one-bead one-compound peptide library | cancer targeting | glioblastoma | integrin | optical imaging
Journal Article
EJNMMI RESEARCH, ISSN 2191-219X, 02/2016, Volume 6
Background: alpha 3 beta 1 integrin is overexpressed in several types of human cancer and is associated with poor prognosis, metastasis, and resistance to... 
One-bead one-compound combinatorial peptide library | Glioblastoma | LIBRARY | Optical imaging | COLONIZATION | alpha 3 beta 1 integrin | BREAST-CANCER CELLS | LUNG-CANCER | COMBINATORIAL CHEMISTRY | LINE | BRAIN METASTASES | Cancer-targeting peptide | RECEPTORS | CARCINOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal Article
EJNMMI Research, ISSN 2191-219X, 12/2016, Volume 6, Issue 1, pp. 1 - 12
α3β1 integrin is overexpressed in several types of human cancer and is associated with poor prognosis, metastasis, and resistance to cancer treatment. We... 
One-bead one-compound combinatorial peptide library | Medicine & Public Health | Orthopedics | α3β1 integrin | Glioblastoma | Oncology | Cancer-targeting peptide | Optical imaging | Nuclear Medicine | Imaging / Radiology | Cardiology
Journal Article
Journal Article
Current protocols in chemical biology, 12/2012, Volume 4, Issue 4, p. 331
One-bead-one-compound (OBOC) libraries consist of structurally related compounds (e.g., peptides) covalently attached to a solid support, with each resin bead... 
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2018, Volume 28, Issue 3, pp. 231 - 234
α-Helix-mediated protein–protein interactions (PPIs) are important targets in biological research and drug development. Peptides containing -amino acid... 
Left-handed α-helix | PPI inhibitors | MDM2 | α,α-Disubstituted amino acids | d-Amino acids | One-bead one-compound | P53 | D-Amino acids | alpha,alpha-Disubstituted amino acids | CHEMISTRY, MEDICINAL | Left-handed alpha-helix | CHEMISTRY, ORGANIC
Journal Article