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Journal Article
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 06/2013, Volume 135, Issue 24, pp. 8782 - 8785
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 47, pp. E10083 - E10091
EmrE is a small multidrug resistance transporter found in Escherichia coli that confers resistance to toxic polyaromatic cations due to its proton-coupled... 
Membrane protein | NMR | Coupled transport | Protein dynamics | Multidrug transport | MULTIDRUG TRANSPORTER | MULTIDISCIPLINARY SCIENCES | protein dynamics | ESCHERICHIA-COLI | ACTIVE-TRANSPORT | coupled transport | P-GLYCOPROTEIN | STATE ANALYSIS | CONFORMATIONAL-CHANGES | SUBSTRATE-BINDING | PROTON RELEASE | multidrug transport | DYNAMICS | membrane protein | RESIDUE | Protons | Antiporters - chemistry | Escherichia coli - drug effects | Proteolipids - metabolism | Substrate Specificity | Onium Compounds - metabolism | Phosphatidylcholines - metabolism | Organophosphorus Compounds - metabolism | Xenobiotics - chemistry | Xenobiotics - pharmacology | Thermodynamics | Biological Transport | Antiporters - genetics | Dicyclohexylcarbodiimide - toxicity | Escherichia coli - metabolism | Organophosphorus Compounds - pharmacology | Protein Interaction Domains and Motifs | Xenobiotics - metabolism | Binding Sites | Onium Compounds - chemistry | Phosphatidylglycerols - metabolism | Recombinant Proteins - metabolism | Gene Expression | Protein Structure, Secondary | Recombinant Proteins - chemistry | Antiporters - metabolism | Escherichia coli Proteins - metabolism | Organophosphorus Compounds - chemistry | Recombinant Proteins - genetics | Onium Compounds - pharmacology | Phosphatidylcholines - chemistry | Molecular Dynamics Simulation | Phosphatidylglycerols - chemistry | Escherichia coli - genetics | Escherichia coli Proteins - genetics | Protein Binding | Kinetics | Drug Resistance, Multiple, Bacterial - genetics | Escherichia coli Proteins - chemistry | Hydrogen-Ion Concentration | Proteolipids - chemistry | Physiological aspects | Carrier proteins | Observations | Protein-protein interactions | Exchanging | Efflux | Drug delivery systems | Nuclear magnetic resonance--NMR | Escherichia coli | Multidrug resistance | Antiport | Substrates | Multidrug resistant organisms | E coli | Cations | Transport | Transporter | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 04/2002, Volume 959, Issue 1, pp. 263 - 274
Journal Article
Biochemical Journal, ISSN 0264-6021, 11/2006, Volume 400, Issue 1, pp. 199 - 208
Lipophilic monocations can pass through phospholipid bilayers and accumulate in negatively-charged compartments such as the mitochondrial matrix, driven by the... 
Mitochondria | Mitochondrial targeting | Lipophilic cations | Membrane potential | Membrane transport | Dications | OXIDATIVE STRESS | 1-METHYL-4-PHENYLPYRIDINIUM | dications | PHOSPHORYLATION | mitochondria | BIOMEMBRANE-PRODUCED ENERGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCTION | PLASMA-MEMBRANE | BIOENERGETICS | ANTIOXIDANT | lipophilic cations | membrane potential | membrane transport | ELECTRIC FORM | PROTEINS | mitochondrial targeting | Uncoupling Agents - pharmacology | Intracellular Membranes - physiology | Mitochondria, Liver - metabolism | Humans | Onium Compounds - metabolism | Organophosphorus Compounds - metabolism | Trityl Compounds - chemistry | Mitochondria, Liver - physiology | Rubidium Radioisotopes - metabolism | Lipids - chemistry | Tritium - metabolism | Adenosine Triphosphate - metabolism | Cations, Divalent - metabolism | Potassium Chloride - pharmacology | Rotenone - pharmacology | Biological Transport - drug effects | Onium Compounds - chemistry | Ionophores - pharmacology | Cations, Divalent - chemistry | Membrane Potentials - drug effects | Jurkat Cells | Rats | Organophosphorus Compounds - chemistry | Mitochondria - metabolism | Mitochondria - drug effects | Membrane Potentials - physiology | Mitochondria, Liver - drug effects | Terphenyl Compounds - metabolism | Terphenyl Compounds - chemistry | Algorithms | Animals | Biological Transport - physiology | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone - pharmacology | Intracellular Membranes - drug effects | Nigericin - pharmacology | Lipid Bilayers - metabolism | Mitochondria - physiology | Intracellular Membranes - metabolism | Trityl Compounds - metabolism | Index Medicus | TPB, tetraphenyl borate anion | ACR, accumulation ratio | ΔΨ, mitochondrial membrane potential | FCS, foetal calf serum | BLM, bilayer planar phospholipid membrane | FCCP, carbonylcyanide-p-trifluoromethoxyphenylhydrazone | PCnP, bistriphenylphosphonium cation linked by an n carbon methylene bridge | TPP, triphenylphosphonium cation | TPMP, methyltriphenylphosphonium cation
Journal Article
Journal Article