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Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 26, pp. 2804 - 2810
Highlights • Liposomes with monophosphoryl lipid A were formulated as adjuvants for haptens. • Heroin analog haptens were conjugated either to the liposomes or... 
Allergy and Immunology | Opiate vaccine | Adjuvant system | Antibodies to heroin haptens | Liposomes containing monophosphoryl lipid A | MEDICINE, RESEARCH & EXPERIMENTAL | SPECIFICITIES | CHOLESTEROL | RATS | ANTIGENS | ALUMINUM-HYDROXIDE | IMMUNOLOGY | DRUG-ABUSE | RELAPSE | PEPTIDES | MORPHINE/HEROIN VACCINE | CODEINE | Adjuvants, Immunologic - administration & dosage | HIV Envelope Protein gp41 - immunology | Lipid A - analogs & derivatives | HIV Envelope Protein gp41 - chemistry | Haptens - immunology | Feasibility Studies | Haptens - chemistry | Lipid A - immunology | Tetanus Toxoid - chemistry | Adjuvants, Immunologic - chemistry | Female | Opioid-Related Disorders - prevention & control | Epitopes, T-Lymphocyte - immunology | Lipid A - chemistry | Lipid A - administration & dosage | Peptides - chemistry | Peptides - immunology | Vaccines - immunology | Heroin - immunology | Opioid-Related Disorders - immunology | Epitopes, T-Lymphocyte - chemistry | Animals | Antibody Formation | Mice | Mice, Inbred BALB C | Liposomes | Tetanus Toxoid - immunology | Viral antibodies | Drug abuse | Alcoholism | Antibodies | Lipids | Tetanus | Heroin | Competition | Peptides | Aluminum | Amino acids | Vaccines | Proteins | Studies | Immunology | Alzheimers disease | Laboratory animals | Binding sites | Cancer | adjuvant system | opiate vaccine | antibodies to heroin haptens
Journal Article
Journal Article
Psychoneuroendocrinology, ISSN 0306-4530, 11/2017, Volume 85, pp. 42 - 48
Journal Article
Journal Article
Journal of NeuroVirology, ISSN 1355-0284, 8/2011, Volume 17, Issue 4, pp. 291 - 302
About one third of acquired immunodeficiency syndrome cases in the USA have been attributed to the use of injected addictive drugs, frequently involving... 
HIV-1 | Neurology | Neurosciences | Biomedicine | Immunology | Opioids | Infectious Diseases | Cyclic AMP (cAMP) | Virology | CHRONICALLY INFECTED PROMONOCYTES | BINDING-PROTEIN | RECEPTOR EXPRESSION | ENHANCES HIV-INFECTION | NEUROSCIENCES | VIROLOGY | LONG TERMINAL REPEAT | HAMSTER OVARY CELLS | TRANSCRIPTION FACTOR | MONONUCLEAR PHAGOCYTES | HUMAN BRAIN-CELLS | MOLECULAR-MECHANISMS | Humans | Opioid-Related Disorders - metabolism | Viral Proteins - metabolism | Substance Withdrawal Syndrome - pathology | CD4-Positive T-Lymphocytes - immunology | Acquired Immunodeficiency Syndrome - immunology | Substance Withdrawal Syndrome - metabolism | Macaca | Simian Acquired Immunodeficiency Syndrome - pathology | Acquired Immunodeficiency Syndrome - virology | Astrocytes - cytology | Microglia - cytology | Virus Replication - drug effects | Acquired Immunodeficiency Syndrome - metabolism | Epidemiologic Studies | Comorbidity | Substance Withdrawal Syndrome - immunology | Disease Progression | Opioid-Related Disorders - epidemiology | Opioid-Related Disorders - virology | Signal Transduction - drug effects | Simian Acquired Immunodeficiency Syndrome - immunology | Acquired Immunodeficiency Syndrome - epidemiology | Mice | Morphine - administration & dosage | Simian Acquired Immunodeficiency Syndrome - metabolism | Opioid-Related Disorders - pathology | United States | Simian Acquired Immunodeficiency Syndrome - epidemiology | Viral Proteins - immunology | Signal Transduction - immunology | Simian Acquired Immunodeficiency Syndrome - virology | Analgesics, Opioid - adverse effects | HIV-1 - physiology | Macrophages - virology | Microglia - immunology | Astrocytes - immunology | Substance Withdrawal Syndrome - epidemiology | CD4-Positive T-Lymphocytes - virology | Astrocytes - virology | Macrophages - immunology | Receptors, Opioid - metabolism | Astrocytes - drug effects | Microglia - drug effects | HIV-1 - drug effects | CD4-Positive T-Lymphocytes - cytology | Virus Replication - immunology | Macrophages - cytology | Substance Withdrawal Syndrome - virology | Opioid-Related Disorders - immunology | Simian Immunodeficiency Virus - physiology | Animals | Receptors, Opioid - immunology | Analgesics, Opioid - administration & dosage | Microglia - virology | Acquired Immunodeficiency Syndrome - pathology | Macrophages - drug effects | Simian Immunodeficiency Virus - drug effects | CD4-Positive T-Lymphocytes - drug effects | Morphine - adverse effects | Adaptations | Neuropathogenesis | Drug abuse | Animal models | Central nervous system | Opioid receptors (type mu) | Intracellular signalling | Morphine | Lymphocytes T | Macrophages | Synergism | Cofactors | Immunosuppressive agents | Risk factors | Life cycle | Heroin | Drug addiction | Cell survival | Opioid receptors | Astrocytes | Withdrawal | Immunodeficiency | CD4 antigen | Microglia | Infection | Monocytes | Molecular modelling
Journal Article
by Long, X and Li, Y and Qiu, S and Liu, J and He, L and Peng, Y
Translational psychiatry, ISSN 2158-3188, 03/2016, Volume 6, Issue 3, pp. e757 - e757
Chronic opioid abusers are more susceptible to bacterial and viral infections, but the molecular mechanism underlying opioid-induced immunosuppression is... 
HEROIN | IMMUNE-SYSTEM | GENE | CHRONIC MORPHINE | BUPRENORPHINE | PSYCHIATRY | INNATE | TNF-ALPHA | MICRORNAS | EXPRESSION | WITHDRAWAL | Tumor Necrosis Factor-alpha - metabolism | Phosphoproteins - drug effects | Humans | Middle Aged | NF-kappa B - immunology | Analgesics, Opioid - pharmacology | Opioid-Related Disorders - metabolism | Male | MicroRNAs - metabolism | NF-kappa B - metabolism | Monocytes - immunology | Cyclic AMP Response Element-Binding Protein - drug effects | Phosphoproteins - metabolism | Case-Control Studies | Young Adult | Signal Transduction - immunology | Analgesics, Opioid - adverse effects | Tumor Necrosis Factor-alpha - immunology | Cyclic AMP Response Element-Binding Protein - immunology | Interleukin-10 - metabolism | Transcription Factor RelA - immunology | Adult | Female | Immunologic Deficiency Syndromes - immunology | Heroin - pharmacology | Cyclic AMP Response Element-Binding Protein A - metabolism | Morphine - pharmacology | MicroRNAs - immunology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Immunologic Deficiency Syndromes - chemically induced | Opioid-Related Disorders - immunology | Monocytes - drug effects | Tumor Necrosis Factor-alpha - drug effects | Transcription Factor RelA - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Cyclic AMP Response Element-Binding Protein A - immunology | MicroRNAs - drug effects | Immunologic Deficiency Syndromes - metabolism | Transcription Factor RelA - drug effects | Cyclic AMP Response Element-Binding Protein A - drug effects | MicroRNAs - genetics | In Vitro Techniques | Interleukin-10 - immunology | NF-kappa B - drug effects | Original
Journal Article
BMC Systems Biology, ISSN 1752-0509, 06/2015, Volume 9, Issue 1, p. 25
Journal Article
Journal Article
Journal of Neuroimmune Pharmacology, ISSN 1557-1890, 12/2011, Volume 6, Issue 4, pp. 477 - 489
Since human immunodeficiency virus (HIV) and hepatitis C virus (HCV) share the same modes of transmission and common risk factors for infection, co-infections... 
Neurosciences | Biomedicine | Immunology | HIV | Opioids | Morphine | HCV | Methadone | Pharmacology/Toxicology | Heroin | Virology | Cell Biology | HEPATITIS-C-VIRUS | HUMAN-IMMUNODEFICIENCY-VIRUS | HIV-1 DISEASE PROGRESSION | NEUROSCIENCES | BLOOD MONONUCLEAR PHAGOCYTES | INJECTION-DRUG USERS | ACTIVE ANTIRETROVIRAL THERAPY | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | METHADONE-MAINTENANCE PATIENTS | HUMAN KUPFFER CELLS | INTERFERON-ALPHA EXPRESSION | Street Drugs - immunology | Coinfection - immunology | Humans | Opioid-Related Disorders - immunology | HIV Infections - immunology | Hepatitis C - immunology | Opioid-Related Disorders - virology | Animals | HIV Infections - complications | HIV Infections - transmission | Hepatitis C - complications | Analgesics, Opioid - immunology | Hepatitis C - transmission | Opioid-Related Disorders - complications | Methadone hydrochloride | Medical colleges | Development and progression | HIV (Viruses) | Biosafety | Risk factors | Diseases | Metabolites | Primates | Cross infection | Nosocomial infections | Hepatitis C virus | Hepatitis C | Health aspects | HIV infection | Antiretroviral drugs | Infections | Narcotics | Human immunodeficiency virus--HIV | Drug abuse | Pathogens | Immune response | Immunomodulation | Mortality | Data processing | Opiates | Immunity | Cofactors | Morbidity | Infection | Infectious diseases | Immunopathogenesis | Replication | Neurotransmission
Journal Article