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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 19, pp. 7427 - 7432
Thyroglobulin (Tg) is the macromolecular precursor of thyroid hormones and is thought to be uniquely expressed by thyroid epithelial cells. Tg and the... 
Connective tissues | Antigens | Messenger RNA | Isotypes | Endocrine system diseases | Epithelial cells | Graves disease | Fibroblasts | Thyroid hormones | Thyrotropin receptors | Autoimmunity | Monocyte | Autoantigen | THYROID-ASSOCIATED OPHTHALMOPATHY | MULTIDISCIPLINARY SCIENCES | CIRCULATING FIBROCYTES | PERIPHERAL-BLOOD | STIMULATING HORMONE | IDENTIFICATION | FIBROBLASTS | autoimmunity | RETRO-ORBITAL TISSUE | GRAVES-DISEASE | monocyte | autoantigen | EXPRESSION | T-CELLS | Immunohistochemistry | Gene Expression | Receptors, Thyrotropin - genetics | Antigens, CD34 - metabolism | Leukocyte Common Antigens - metabolism | Receptors, Thyrotropin - metabolism | Thyroglobulin - metabolism | Humans | RNA, Messenger - genetics | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Graves Ophthalmopathy - genetics | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Orbit - metabolism | Graves Ophthalmopathy - metabolism | RNA Interference | Thyroglobulin - genetics | Graves Ophthalmopathy - pathology | Thyroid Gland - cytology | Thyroid Gland - metabolism | Connective Tissue Cells - metabolism | Fibroblasts - metabolism | Physiological aspects | Thyrotropin | Research | Thyroglobulin | Proteins | Tissue | Thyroid gland | Hormones | Autoimmune diseases | Cells | Index Medicus | Biological Sciences
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 07/2013, Volume 98, Issue 7, pp. 2783 - 2790
Context: Thyroid-associated ophthalmopathy (TAO) manifests as inflammation of orbital connective tissue. Bone marrow–derived CD34+ fibrocytes infiltrate the... 
CIGARETTE-SMOKING | PROTEIN | THYROTROPIN RECEPTOR | IFN-GAMMA | DISEASE | TISSUE | ENDOCRINOLOGY & METABOLISM | ENDOPEROXIDE H SYNTHASE-2 | IL-1-BETA | INDUCTION | GRAVES OPHTHALMOPATHY | Leukocytes - pathology | Fibroblasts - secretion | Antigens, CD34 - metabolism | Orbit - immunology | Graves Ophthalmopathy - surgery | Humans | Interleukin 1 Receptor Antagonist Protein - genetics | Interleukin-1alpha - metabolism | Orbit - surgery | Interleukin-1beta - genetics | RNA, Messenger - metabolism | Cyclooxygenase 2 - biosynthesis | Leukocytes - immunology | Graves Ophthalmopathy - metabolism | Cyclooxygenase 2 - genetics | Interleukin-1beta - metabolism | Interleukin 1 Receptor Antagonist Protein - metabolism | Cell Transdifferentiation | Interleukin 1 Receptor Antagonist Protein - secretion | Interleukin-1alpha - genetics | Interleukin-1beta - biosynthesis | Orbit - pathology | Fibroblasts - metabolism | Recombinant Proteins - metabolism | Promoter Regions, Genetic | Disease Susceptibility | Cells, Cultured | Gene Expression Regulation | Fibroblasts - pathology | RNA Stability | Graves Ophthalmopathy - immunology | Orbit - metabolism | Cyclooxygenase 2 - metabolism | Fibroblasts - immunology | Interleukin-1alpha - biosynthesis | Leukocytes - secretion | Graves Ophthalmopathy - pathology | Leukocytes - metabolism | Index Medicus | Abridged Index Medicus | Endocrine Research
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 03/2017, Volume 102, Issue 3, pp. 776 - 785
Context: The sources and biological impact of 3,30,5,50 tetraiodothyroacetic acid (TA4) are uncertain. CD34(+) fibrocytes express several proteins involved in... 
THYROTROPIN RECEPTOR | ENDOCRINOLOGY & METABOLISM | HYALURONAN SYNTHESIS | ANTERIOR-PITUITARY-CELLS | MOLECULAR PATHOGENESIS | THYROXINE | HUMAN ORBITAL FIBROBLASTS | INTEGRIN ALPHA(V)BETA | INDUCTION | EXPRESSION | FIBROCYTES | Graves Disease - blood | Immunoassay | Retinal Pigment Epithelium - metabolism | Humans | Middle Aged | Ependymoglial Cells - metabolism | Thyroxine - blood | Male | Case-Control Studies | Young Adult | Tandem Mass Spectrometry | Flow Cytometry | Thyroxine - analogs & derivatives | Immunoglobulins, Thyroid-Stimulating - metabolism | Aged, 80 and over | Chromatography, Liquid | Adult | Female | Hyaluronan Synthases | Interleukin-6 - metabolism | Real-Time Polymerase Chain Reaction | Fibroblasts - metabolism | Orbit | Receptors, Thyrotropin - metabolism | Cells, Cultured | Thyrotropin - metabolism | Triiodothyronine - blood | Autoradiography | Glucuronosyltransferase - metabolism | Prostaglandin-Endoperoxide Synthases - metabolism | Hyaluronic Acid - metabolism | Sex Factors | Graves Ophthalmopathy - blood | Graves Disease - complications | Aged | HeLa Cells | Retinal Pigment Epithelium - cytology | Graves Ophthalmopathy - etiology | Cell culture | Correlation | Graves' disease | Pathogenesis | Epithelial cells | Interleukin | Retina | Thyroid gland | Hormones | Propylthiouracil | Hyaluronan synthase | Interleukin 6 | Proteins | Connective tissues | Hyaluronan | Thyroxine | Fibroblasts | Triiodothyronine | Thyroid hormones | Thyroid | CD34 antigen | Immunoglobulins | Mass spectroscopy | Liquid chromatography | Polymerase chain reaction | Serum levels | Thyroid-stimulating hormone | Medical centres | Stem cells | Mass spectrometry | Index Medicus | Abridged Index Medicus
Journal Article
The Journal of Membrane Biology, ISSN 0022-2631, 8/2017, Volume 250, Issue 4, pp. 393 - 406
To quantitatively examine the effect of membrane organization on lateral diffusion, we studied fluorescent carbocyanine lipid analogues and EGFP-tagged,... 
Life Sciences | Biochemistry, general | Giant unilamellar vesicles | Human Physiology | Fluorescent lipid | Giant plasma membrane vesicles | Interleukin-4 receptor | Diffusion coefficient | Fluorescence correlation spectroscopy | PHYSIOLOGY | LIGAND-BINDING | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODEL | HYDROPHOBIC MISMATCH | CELL BIOLOGY | UNILAMELLAR VESICLES | LIPID RAFTS | PROTEINS | LATERAL DIFFUSION | LIVING CELLS | Carbocyanines - chemistry | Humans | Unilamellar Liposomes - chemistry | Green Fluorescent Proteins - genetics | Histidine - metabolism | Phosphatidylcholines - metabolism | Recombinant Fusion Proteins - metabolism | Interleukin-4 Receptor alpha Subunit - genetics | Cell Membrane - chemistry | Cholesterol - chemistry | HEK293 Cells | Cell Membrane - metabolism | Interleukin-4 - genetics | Diffusion | Fluorescent Dyes - chemistry | Green Fluorescent Proteins - metabolism | Gene Expression | Interleukin-4 Receptor alpha Subunit - metabolism | Sphingomyelins - metabolism | Interleukin-4 - metabolism | Oligopeptides - genetics | Histidine - genetics | Spectrometry, Fluorescence | Oligopeptides - metabolism | Phosphatidylcholines - chemistry | Cholesterol - metabolism | Plasmids - metabolism | Protein Transport | Unilamellar Liposomes - metabolism | Plasmids - chemistry | Recombinant Fusion Proteins - genetics | Sphingomyelins - chemistry | Kinetics | Interleukins | Analysis | Fluorescence | Lipids | Cell membranes | Muscle proteins | Membrane proteins | Viscosity | Fluorescence spectroscopy | Plasma | Diffusion rate | Scanning | Lateral diffusion | Interleukin | Two dimensional models | Proteins | Receptors | Interleukin 4 | Vesicles | Actin | Dithiothreitol | Circular orbits | Spectroscopy | Membrane vesicles | Biophysics | Cells (biology) | Liposomes | Plasmas (physics) | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, pp. e34173 - e34173
Insulin-like growth factor-1 receptor (IGF-1R) comprises two subunits, including a ligand binding domain on extra-cellular IGF-1R alpha and a tyrosine... 
B-CELLS | HUMAN-SKIN FIBROBLASTS | EGF-RECEPTOR | MULTIDISCIPLINARY SCIENCES | LEUKOREGULIN INDUCTION | HYALURONAN SYNTHESIS | ENDOPEROXIDE H SYNTHASE-2 | GLYCOSAMINOGLYCAN SYNTHESIS | FACTOR-I RECEPTOR | GROWTH-FACTOR RECEPTOR-1 | T-CELLS | ADAM17 Protein | Graves Disease - metabolism | Phosphorylation - physiology | Chromatin - metabolism | Receptor, IGF Type 1 - metabolism | Humans | Cells, Cultured | Protein Transport - physiology | Interleukin-16 - metabolism | Orbit - metabolism | ADAM Proteins - metabolism | Cell Nucleus - metabolism | Glucocorticoids - metabolism | Chemokine CCL5 - metabolism | Graves Disease - pathology | Insulin-Like Growth Factor I - metabolism | Orbit - cytology | Fibroblasts - metabolism | Immunoglobulin G - metabolism | Tyrosine | Physiological aspects | Chromatin | Corticosteroids | B cells | Immunoglobulin G | Phosphorylation | Dehydrogenases | Glucocorticoids | Graves' disease | Insulin-like growth factor I | Pathogenesis | RANTES | Insulin-like growth factors | Thyroid gland | Kinases | Cell surface | Nuclei | Accumulation | Proteins | Immunology | Coding | Fibroblasts | Fusion protein | Immunoglobulins | Departments | Cytokines | Internal medicine | Crosslinking | Breast cancer | Metabolism | Gene expression | Insulin | Interleukin 16 | Medicine | Monoclonal antibodies | Ligands | Nuclei (cytology) | Endocrinology | Apoptosis | Index Medicus
Journal Article
Journal Article
American Journal of Hematology, ISSN 0361-8609, 09/2013, Volume 88, Issue 9, pp. 730 - 735
The etiology and pathogenesis of ocular adnexal extranodal marginal zone lymphoma (OAEMZL) are still unknown and the association with Chlamydophila psittaci... 
CHLAMYDIA-PSITTACI | CELL LYMPHOMA | VARIABLE FREQUENCIES | NO EVIDENCE | CHROMOSOMAL-ABERRATION | HEMATOLOGY | NF-KAPPA-B | MALT LYMPHOMA | HELICOBACTER-PYLORI | ASSOCIATION | A20 | Translocation, Genetic | Humans | Middle Aged | Molecular Sequence Data | Male | Intracellular Signaling Peptides and Proteins - metabolism | Neoplasm Proteins - metabolism | CARD Signaling Adaptor Proteins - genetics | Conjunctiva - metabolism | DNA-Binding Proteins - metabolism | CARD Signaling Adaptor Proteins - metabolism | Conjunctiva - pathology | Base Sequence | Aged, 80 and over | Adult | Female | Lymphoma, B-Cell, Marginal Zone - pathology | Tumor Necrosis Factor alpha-Induced Protein 3 | Chlamydophila psittaci | Lacrimal Apparatus - pathology | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Orbit - pathology | Eye Neoplasms - genetics | Eye Neoplasms - pathology | Myeloid Differentiation Factor 88 - genetics | Guanylate Cyclase - metabolism | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Lacrimal Apparatus - metabolism | Lymphoma, B-Cell, Marginal Zone - genetics | Orbit - metabolism | Eye Neoplasms - metabolism | Lymphoma, B-Cell, Marginal Zone - metabolism | Guanylate Cyclase - genetics | Aged | Mutation | Myeloid Differentiation Factor 88 - metabolism | Development and progression | Genetic aspects | Non-Hodgkin's lymphomas | Analysis | Cancer | Index Medicus | translocations | MALT lymphoma | mutations | ocular adnexa | NF-kB
Journal Article
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 1/2005, Volume 168, Issue 1, pp. 141 - 153
Journal Article