Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (44925) 44925
Publication (5372) 5372
Book Review (4391) 4391
Book / eBook (1130) 1130
Book Chapter (327) 327
Conference Proceeding (116) 116
Newsletter (30) 30
Dissertation (17) 17
Government Document (14) 14
Data Set (12) 12
Magazine Article (10) 10
Reference (3) 3
Paper (2) 2
Presentation (2) 2
Newspaper Article (1) 1
Trade Publication Article (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (42888) 42888
animals (33819) 33819
organ specificity (22236) 22236
humans (16400) 16400
male (15590) 15590
female (11761) 11761
rats (11691) 11691
mice (11229) 11229
biochemistry & molecular biology (8300) 8300
neurosciences (6329) 6329
molecular sequence data (5902) 5902
gene expression (4985) 4985
cell biology (4828) 4828
amino acid sequence (4725) 4725
expression (4581) 4581
species specificity (4096) 4096
proteins (3972) 3972
base sequence (3962) 3962
sense organs (3839) 3839
analysis (3826) 3826
physiology (3788) 3788
research (3622) 3622
physiological aspects (3320) 3320
article (3230) 3230
research article (3201) 3201
kinetics (3174) 3174
brain - metabolism (3096) 3096
adult (2999) 2999
multidisciplinary sciences (2938) 2938
genes (2888) 2888
brain (2790) 2790
medicine (2730) 2730
mice, inbred c57bl (2694) 2694
middle aged (2681) 2681
organ size (2585) 2585
cells, cultured (2531) 2531
cloning, molecular (2519) 2519
immunohistochemistry (2497) 2497
endocrinology & metabolism (2475) 2475
rats, sprague-dawley (2435) 2435
immunology (2429) 2429
cells (2418) 2418
rna, messenger - genetics (2392) 2392
rodents (2349) 2349
gene expression regulation (2345) 2345
rna, messenger - metabolism (2339) 2339
organ specificity - genetics (2274) 2274
organ culture techniques (2218) 2218
gene-expression (2201) 2201
time factors (2197) 2197
science (2157) 2157
liver - metabolism (2143) 2143
biology (2133) 2133
abridged index medicus (2097) 2097
organs (2023) 2023
cell line (1995) 1995
aged (1926) 1926
developmental biology (1880) 1880
neurons (1878) 1878
liver (1856) 1856
genetic aspects (1854) 1854
signal transduction (1849) 1849
rats, inbred strains (1771) 1771
pregnancy (1756) 1756
identification (1749) 1749
biophysics (1745) 1745
rats, wistar (1742) 1742
genetics & heredity (1717) 1717
sequence homology, amino acid (1692) 1692
gene (1679) 1679
mice, transgenic (1664) 1664
life sciences (1639) 1639
phylogeny (1631) 1631
transcription, genetic (1618) 1618
metabolism (1615) 1615
mice, knockout (1613) 1613
protein (1592) 1592
transplantation (1564) 1564
messenger-rna (1542) 1542
rat (1503) 1503
gene expression regulation, developmental (1488) 1488
surgery (1482) 1482
polymerase chain reaction (1481) 1481
gene expression profiling (1429) 1429
in-vivo (1407) 1407
rna (1402) 1402
health aspects (1397) 1397
rabbits (1353) 1353
apoptosis (1350) 1350
protein binding (1344) 1344
plant sciences (1343) 1343
rna, messenger - analysis (1343) 1343
rna, messenger - biosynthesis (1343) 1343
mutation (1342) 1342
genetic structures (1330) 1330
activation (1328) 1328
sequence alignment (1328) 1328
sensitivity and specificity (1322) 1322
mouse (1302) 1302
cattle (1262) 1262
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (924) 924
Collection Dvlpm't (Acquisitions) - Closed Orders (62) 62
UofT at Mississauga - Stacks (46) 46
UTL at Downsview - May be requested (39) 39
UofT at Scarborough - Stacks (25) 25
Collection Dvlpm't (Acquisitions) - Vendor file (23) 23
Scarborough Hospital - General (21) 21
St. Michael's College (John M. Kelly) - 2nd Floor (17) 17
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (17) 17
Online Resources - Online (16) 16
St. Michael's Hospital - Stacks (16) 16
Royal Ontario Museum - Stacks (14) 14
Lakeridge Health Sciences - Oshawa (13) 13
Toronto East General Hospital - Stacks (12) 12
Providence Healthcare - Stacks (10) 10
St. Augustine's Seminary - Stacks (9) 9
Humber River Regional Hospital - Finch Stacks (8) 8
Robarts - Stacks (8) 8
West Park Healthcare Centre - Stacks (8) 8
Holland Bloorview Kids Rehabilitation - Stacks (6) 6
Humber River Regional Hospital - Church Stacks (6) 6
OISE - Stacks (6) 6
Providence Healthcare - Reference (6) 6
Scarborough Hospital - Birchmount (6) 6
Trillium Health Centre - Stacks (6) 6
Women's College Hospital - Stacks (5) 5
Earth Sciences (Noranda) - Stacks (4) 4
Gerstein Science - Missing (4) 4
Markham Stouffville Hospital - Stacks (4) 4
Trinity College (John W Graham) - Stacks (4) 4
Victoria University E.J. Pratt - Stacks (4) 4
Credit Valley Hospital - Reference (3) 3
Credit Valley Hospital - Stacks (3) 3
Gerstein Science - Circulation Desk (3) 3
Gerstein Science - Reference (3) 3
Regis College - Stacks (3) 3
St Josephs Health Centre - Stacks (3) 3
Toronto East General Hospital - Online (3) 3
Dentistry (Harry R Abbott) - Stacks (2) 2
Law (Bora Laskin) - Stacks (2) 2
St. Michael's College (John M. Kelly) - 3rd Floor (2) 2
Toronto East General Hospital - Reference (2) 2
Trinity College (John W Graham) - Wycliffe Storage (2) 2
Victoria University Emmanuel College - Stacks (2) 2
West Park Healthcare Centre - Hospital Department (2) 2
Baycrest Hospital - Stacks (1) 1
Credit Valley Hospital - Reserve desk (1) 1
Dentistry (Harry R Abbott) - Course Reserves (1) 1
Dentistry (Harry R Abbott) - May be requested in 6-10 wks (1) 1
Earth Sciences (Noranda) - Missing (1) 1
Engineering & Comp. Sci. - Stacks (1) 1
Gerstein Science - May be requested (1) 1
Gerstein Science - May be requested in 6-10 wks (1) 1
Gerstein Science - Reference Desk (1) 1
Humber River Regional Hospital - Church Reference (1) 1
Knox College (Caven) - Stacks (1) 1
Mt Sinai Hospital - Pathology (1) 1
New College (Ivey) - Stacks (1) 1
New College (Ivey) - Withdrawn (1) 1
Not Returned (1) 1
Providence Healthcare - Reserve desk (1) 1
Providence Healthcare - Withdrawn (1) 1
Royal Ontario Museum - Periodical Stacks (1) 1
St. Augustine's Seminary - Reference (1) 1
St. Michael's Hospital - Circulation Desk (1) 1
Sunnybrook Health Sciences Centre - Holland Stacks (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Reference (1) 1
Trillium Health Centre - Reserve desk (1) 1
Trinity College (John W Graham) - Reference (1) 1
Trinity College (John W Graham) - Storage (1) 1
University College (Laidlaw) - Stacks (1) 1
UofT at Mississauga - Oversize (1) 1
UofT at Mississauga - Reference (1) 1
Victoria University Emmanuel College - Reference (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (45531) 45531
Russian (263) 263
French (127) 127
German (117) 117
Japanese (79) 79
Spanish (59) 59
Chinese (23) 23
Ukrainian (13) 13
Italian (11) 11
Polish (5) 5
Arabic (4) 4
Czech (3) 3
Turkish (3) 3
Persian (2) 2
Hebrew (1) 1
Hungarian (1) 1
Korean (1) 1
Latin (1) 1
Serbian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Characterization of ceramide synthase 2: Tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
by Laviad, Elad L and Albee, Lee and Pankova-Kholmyansky, Irene and Epstein, Sharon and Park, Hyejung and Merrill Jr, Alfred H and Futerman, Anthony H
Journal of Biological Chemistry, ISSN 0021-9258, 02/2008, Volume 283, Issue 9, pp. 5677 - 5684
Ceramide is an important lipid signaling molecule and a key intermediate in sphingolipid biosynthesis. Recent studies have implied a previously unappreciated... 
Oxidoreductases - antagonists & inhibitors | Cell Line | Lysophospholipids - metabolism | Ceramides - metabolism | Oxidoreductases - genetics | Humans | RNA, Messenger - genetics | Substrate Specificity - physiology | Sphingolipids - metabolism | Gene Expression Regulation, Enzymologic - physiology | Ceramides - genetics | RNA, Messenger - biosynthesis | Lysophospholipids - genetics | Sphingosine - analogs & derivatives | Animals | Sphingolipids - genetics | Sphingosine - genetics | Signal Transduction - physiology | Mice | Sphingosine - metabolism | Lipid Metabolism - physiology | Organ Specificity - physiology | Oxidoreductases - biosynthesis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text VEGF-Induced Adult Neovascularization: Recruitment, Retention, and Role of Accessory Cells
by Grunewald, Myriam and Avraham, Inbal and Dor, Yuval and Bachar-Lustig, Esther and Itin, Ahuva and Yung, Steffen and Chimenti, Stephano and Landsman, Limor and Abramovitch, Rinat and Keshet, Eli
Cell, ISSN 0092-8674, 2006, Volume 124, Issue 1, pp. 175 - 189
Adult neovascularization relies on the recruitment of circulating cells, but their angiogenic roles and recruitment mechanisms are unclear. We show that the... 
PROGENITOR CELLS | VASCULARIZATION | ENGRAFTMENT | REGENERATION | VASCULATURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEMATOPOIETIC STEM-CELLS | ACUTE MYOCARDIAL-INFARCTION | TUMOR ANGIOGENESIS | ENDOTHELIAL GROWTH-FACTOR | TRANSPLANTATION | CELL BIOLOGY | Neovascularization, Physiologic - drug effects | Heart - physiology | Myeloid Cells - physiology | Bone Marrow Cells - physiology | Organ Specificity - genetics | Liver - drug effects | Hematopoietic Stem Cells - physiology | Bone Marrow Cells - drug effects | Myeloid Cells - drug effects | Vascular Endothelial Growth Factor A - pharmacology | Endothelial Cells - physiology | Organ Specificity - physiology | Hematopoietic Stem Cells - drug effects | Chemokine CXCL12 | Bone Marrow Cells - cytology | Mice, Transgenic | Mice, SCID | Neovascularization, Physiologic - physiology | Animals | Endothelial Cells - cytology | Heart - drug effects | Liver - physiology | Chemokines, CXC - physiology | Mice, Inbred NOD | Mice | Vascular Endothelial Growth Factor A - physiology | Endothelial Cells - drug effects | Endothelial growth factors | Neovascularization | Research | Employee recruitment | Vascular endothelial growth factor | Analysis | Endothelium | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Human Myocardial Pericytes: Multipotent Mesodermal Precursors Exhibiting Cardiac Specificity
by Chen, William C. W and Baily, James E and Corselli, Mirko and Díaz, Mary E and Sun, Bin and Xiang, Guosheng and Gray, Gillian A and Huard, Johnny and Péault, Bruno
STEM CELLS, ISSN 1066-5099, 02/2015, Volume 33, Issue 2, pp. 557 - 573
Perivascular mesenchymal precursor cells (i.e., pericytes) reside in skeletal muscle where they contribute to myofiber regeneration; however, the existence of... 
Mesenchymal stem cell | Myocardium | Tissue specificity | Pericyte | Coronary vessel | Stem cell | RANDOMIZED PHASE-1 TRIAL | CARDIOMYOCYTE RENEWAL | BONE-MARROW | SATELLITE CELLS | MESENCHYMAL STEM-CELLS | HUMAN SKELETAL-MUSCLE | PERIVASCULAR CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | HEART REGENERATION | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PDGFR-ALPHA | HEMATOLOGY | HUMAN FETAL | Antigens, Differentiation - biosynthesis | Multipotent Stem Cells - cytology | Humans | Multipotent Stem Cells - metabolism | Myocardium - metabolism | Pericytes - cytology | Pericytes - metabolism | Cells, Cultured | Female | Male | Myocardium - cytology | Organ Specificity - physiology | Muscles | Platelet-derived growth factor | Muscle proteins | Stem cells | Myosin | Musculoskeletal system | Smooth muscle | Index Medicus | mesenchymal stem cell | myocardium | pericyte | stem cell | tissue specificity | coronary vessel
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text The Burmese python genome reveals the molecular basis for extreme adaptation in snakes
by Todd A. Castoe and A. P. Jason de Koning and Kathryn T. Hall and Daren C. Card and Drew R. Schield and Matthew K. Fujita and Robert P. Ruggiero and Jack F. Degner and Juan M. Daza and Wanjun Gu and Jacobo Reyes-Velasco and Kyle J. Shaney and Jill M. Castoe and Samuel E. Fox and Alex W. Poole and Daniel Polanco and Jason Dobry and Michael W. Vandewege and Qing Li and Ryan K. Schott and Aurélie Kapusta and Patrick Minx and Cédric Feschotte and Peter Uetz and David A. Ray and Federico G. Hoffmann and Robert Bogden and Eric N. Smith and Belinda S. W. Chang and Freek J. Vonk and Nicholas R. Casewell and Christiaan V. Henkel and Michael K. Richardson and Stephen P. Mackessy and Anne M. Bronikowsi and Mark Yandell and Wesley C. Warren and Stephen M. Secor and David D. Pollock
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2013, Volume 110, Issue 51, pp. 20645 - 20650
Snakes possess many extreme morphological and physiological adaptations. Identification of the molecular basis of these traits can provide novel understanding... 
Reptiles | Vertebrates | Genomics | Genes | Pythons | Isochores | Evolution | Genomes | Snakes | Human organs | Comparative genomics | Physiological remodeling | Systems biology | Transcriptomics | Transposable elements | systems biology | SYSTEM | MULTIDISCIPLINARY SCIENCES | LIZARD | MODEL | comparative genomics | DISCOVERY | EVOLUTION | GENES | transcriptomics | transposable elements | PROTEINS | REPTILES | physiological remodeling | Transcription, Genetic - physiology | Animals | Genome - physiology | Humans | Adaptation, Physiological - physiology | Cell Cycle - physiology | Gene Expression Regulation - physiology | Boidae - genetics | Boidae - metabolism | Evolution, Molecular | Organ Specificity - physiology | Research | Adaptation (Biology) | Molecular genetics | Morphology (Animals) | Genotype & phenotype | Morphology | Cell cycle | Comparative analysis | Deoxyribonucleic acid--DNA | Index Medicus | Biological Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Tissue Specificity: Store-Operated Ca 2+ Entry in Cardiac Myocytes
by Bootman, Martin D and Rietdorf, Katja
Advances in experimental medicine and biology, ISSN 0065-2598, 2017, Volume 993, p. 363
Calcium (Ca ) is a key regulator of cardiomyocyte contraction. The Ca channels, pumps, and exchangers responsible for the cyclical cytosolic Ca signals that... 
Animals | Calcium Channels - metabolism | Calcium - metabolism | Calcium Signaling - physiology | Humans | TRPC Cation Channels - metabolism | Myocytes, Cardiac - metabolism | Stromal Interaction Molecules - metabolism | Organ Specificity - physiology
Journal Article
Details down arrow
6. Full Text The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthood
by Makiko, Mizutani and Pino, Paula A and Saederup, Noah and Charo, Israel F and Ransohoff, Richard M and Cardona, Astrid E
Journal of Immunology, ISSN 0022-1767, 01/2012, Volume 188, Issue 1, pp. 29 - 36
Microglial cells are difficult to track during development because of the lack of specific reagents for myeloid subpopulations. To further understand how... 
CELLS | MARROW-DERIVED MICROGLIA | ORIGIN | ALZHEIMERS-DISEASE | MACROPHAGES | CENTRAL-NERVOUS-SYSTEM | BLOOD MONOCYTES | IMMUNOLOGY | CHEMOKINE RECEPTORS | RAMIFIED MICROGLIA | BRAIN | Microglia - cytology | Receptors, CCR2 - genetics | Microglia - metabolism | Receptors, CCR2 - immunology | Embryonic Development - physiology | Mice, Transgenic | Receptors, Chemokine - immunology | Animals | Microglia - immunology | Embryo, Mammalian - embryology | Embryo, Mammalian - immunology | Myeloid Cells - immunology | Receptors, Chemokine - biosynthesis | Myeloid Cells - metabolism | Female | Mice | Receptors, Chemokine - genetics | CX3C Chemokine Receptor 1 | Receptors, CCR2 - biosynthesis | Gene Expression Regulation, Developmental - physiology | Organ Specificity - physiology | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Overlapping substrate and inhibitor specificity of human and murine ABCG2
by Bakhsheshian, Joshua and Hall, Matthew D and Robey, Robert W and Herrmann, Michelle A and Chen, Jin-Qiu and Bates, Susan E and Gottesman, Michael M
Drug Metabolism and Disposition, ISSN 0090-9556, 10/2013, Volume 41, Issue 10, pp. 1805 - 1812
ABCG2 (also known as breast cancer resistance protein) is an ATP-binding cassette (ABC) transporter localized to the plasma membrane where it mediates the... 
CYCLOSPORINE-A | PHOTODYNAMIC THERAPY | IN-VIVO | PHARMACOLOGY & PHARMACY | HALF-TRANSPORTER | DRUG-RESISTANCE | FUMITREMORGIN-C | MULTIDRUG-RESISTANCE | BREAST-CANCER RESISTANCE | COLON-CARCINOMA CELLS | P-GLYCOPROTEIN | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Cell Line | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Substrate Specificity - physiology | Neoplasm Proteins - antagonists & inhibitors | Porphyrins - pharmacology | Neoplasm Proteins - metabolism | Animals | MCF-7 Cells | Fibroblasts - drug effects | ATP-Binding Cassette Transporters - metabolism | Cell Line, Tumor | Mice | Mitoxantrone - pharmacology | Drug Resistance, Multiple - physiology | Drug Resistance, Neoplasm - physiology | 3T3 Cells | ATP-Binding Cassette Transporters - antagonists & inhibitors | Fibroblasts - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Tissue Specificity: SOCE: Implications for Ca 2+ Handling in Endothelial Cells
by Blatter, Lothar A
Advances in experimental medicine and biology, ISSN 0065-2598, 2017, Volume 993, p. 343
Many cellular functions of the vascular endothelium are regulated by fine-tuned global and local, microdomain-confined changes of cytosolic free Ca ([Ca ] ).... 
Animals | Calcium Channels - metabolism | Calcium - metabolism | Endothelial Cells - metabolism | Endothelium, Vascular - metabolism | Calcium Signaling - physiology | Humans | Endoplasmic Reticulum - metabolism | Organ Specificity - physiology
Journal Article
Details down arrow
9. Tissue Specificity: The Role of Organellar Membrane Nanojunctions in Smooth Muscle Ca 2+ Signaling
by Fameli, Nicola and Evans, A Mark and van Breemen, Cornelis
Advances in experimental medicine and biology, ISSN 0065-2598, 2017, Volume 993, p. 321
In this chapter we examine the importance of cytoplasmic nanojunctions-nanometer scale appositions between organellar membranes including the molecular... 
Animals | Muscle, Smooth, Vascular - metabolism | Calcium - metabolism | Calcium Signaling - physiology | Humans | Intercellular Junctions - metabolism | Cell Membrane - metabolism | Sarcoplasmic Reticulum - metabolism | Organ Specificity - physiology
Journal Article
Details down arrow
10. Full Text ZIP8 is an iron and zinc transporter whose cell-surface expression is up-regulated by cellular iron loading
by Wang, Chia-Yu and Jenkitkasemwong, Supak and Duarte, Stephanie and Sparkman, Brian K and Shawki, Ali and Mackenzie, Bryan and Knutson, Mitchell D
Journal of Biological Chemistry, ISSN 0021-9258, 10/2012, Volume 287, Issue 41, pp. 34032 - 34043
ZIP8 (SLC39A8) belongs to the ZIP family of metal-ion transporters. Among the ZIP proteins, ZIP8 is most closely related to ZIP14, which can transport iron,... 
RAT-LIVER | OVERLOAD | TRANSFERRIN-BOUND IRON | PROTEIN | METAL-ION TRANSPORTER | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | RECEPTOR EXPRESSION | GENE ENCODES | FUNCTIONAL-PROPERTIES | HEMOCHROMATOSIS | Cation Transport Proteins - biosynthesis | Humans | Xenopus laevis | Rats | Cell Membrane - genetics | Iron - metabolism | Oocytes | Animals | Up-Regulation - physiology | HEK293 Cells | Cell Line, Tumor | Cation Transport Proteins - genetics | Cell Membrane - metabolism | Ion Transport - physiology | Organ Specificity - physiology | Index Medicus | Placenta | Hemochromatosis | Transporters | ZIP Protein | Iron | Metabolism | Pancreas | Cobalt | Zinc
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Suboptimization of developmental enhancers
by Farley, Emma K and Olson, Katrina M and Zhang, Wei and Brandt, Alexander J and Rokhsar, Daniel S and Levine, Michael S
Science, ISSN 0036-8075, 10/2015, Volume 350, Issue 6258, pp. 325 - 328
Transcriptional enhancers direct precise on-off patterns of gene expression during development. To explore the basis for this precision, we conducted a... 
TRANSCRIPTION FACTORS | MATERNAL GATA | COMPLEX | SUPER-ENHANCERS | ETS | DNA | MULTIDISCIPLINARY SCIENCES | CELL IDENTITY | NEURAL-TUBE | EYE ENHANCER | SIGNALING ESTABLISHES | Consensus Sequence | Fas-Associated Death Domain Protein - metabolism | Molecular Sequence Data | Otx Transcription Factors - metabolism | Ciona intestinalis - genetics | Fibroblast Growth Factors - metabolism | Organ Specificity - genetics | Animals | GATA Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Base Sequence | Ciona intestinalis - growth & development | Enhancer Elements, Genetic - genetics | Enhancer Elements, Genetic - physiology | Binding Sites | Organ Specificity - physiology | Embryonic development | Physiological aspects | Fibroblast growth factors | Genetic aspects | Genetic transcription | Observations | Binding sites (Biochemistry) | Gene expression | Developmental biology | Index Medicus | Intervals | Binding | Genes | Activation | Embryos | Binding sites | Optimization
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
by Ina Koch and Regina Weil and Renzo Wolbold and Jürgen Brockmöller and Elisabeth Hustert and Oliver Burk and Andreas Nuessler and Peter Neuhaus and Michel Eichelbaum and Ulrich Zanger and Leszek Wojnowski
Drug Metabolism and Disposition, ISSN 0090-9556, 10/2002, Volume 30, Issue 10, pp. 1108 - 1114
The elucidation of the individual contributions of the four CYP3A genes to the overall CYP3A activity has been hampered by similarities in their sequence and... 
PREGNANE-X RECEPTOR | MESSENGER-RNA | SELECTIVE EXPRESSION | HUMAN CYP3A | HUMAN HEPATOCYTES | DRUG-INTERACTIONS | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | HUMAN BLOOD | QUANTITATIVE RT-PCR | ADULT HUMAN-LIVER | RNA, Messenger - biosynthesis | Liver - enzymology | Cytochrome P-450 CYP3A | Isoenzymes - genetics | Gene Expression - physiology | Humans | Cytochrome P-450 Enzyme System - biosynthesis | Cytochrome P-450 Enzyme System - genetics | Isoenzymes - biosynthesis | Genetic Variation - physiology | Organ Specificity - physiology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Coupling governs entrainment range of circadian clocks
by Granada, Adrián E and Herzel, Hanspeter and Abraham, Ute and Westermark, Pål O and Heine, Markus and Kramer, Achim
Molecular Systems Biology, ISSN 1744-4292, 11/2010, Volume 6, Issue 1, pp. 438 - n/a
Circadian clocks are endogenous oscillators driving daily rhythms in physiology and behavior. Synchronization of these timers to environmental light–dark... 
mathematical modeling | coupling | circadian clock | entrainment | oscillatorregulation | entrainment; mathematical modeling; oscillator | RESPONSE CURVE | oscillator | LIGHT-DARK CYCLES | BIOCHEMISTRY & MOLECULAR BIOLOGY | RAT SUPRACHIASMATIC NUCLEUS | MAMMALIAN RETINA | NOCTURNAL RODENTS | RHYTHMS | OSCILLATORS | RUNNING ACTIVITY | GENE-EXPRESSION | FUNCTIONAL-ANALYSIS | Models, Theoretical | Luciferases - metabolism | Tissue Culture Techniques | Cells, Cultured | Male | Mice, Transgenic | Circadian Clocks - genetics | Photoperiod | Lung - physiology | Luciferases - genetics | Suprachiasmatic Nucleus - physiology | Animals | Period Circadian Proteins - metabolism | Biological Clocks - physiology | Period Circadian Proteins - genetics | Time Factors | Single-Cell Analysis - methods | Biological Clocks - genetics | Suprachiasmatic Nucleus - metabolism | Lung - metabolism | Mice | Circadian Clocks - physiology | Organ Specificity - physiology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights