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1. Full Text Impact of OATP transporters on pharmacokinetics
by Kalliokoski, A and Niemi, M
British journal of pharmacology, ISSN 0007-1188, 10/2009, Volume 158, Issue 3, pp. 693 - 705
repaglinide | SLCO1B1 | organic anion transporting polypeptide | statin | transporter | simvastatin | OATP | OATP1B1 | pharmacogenetics | Organic anion transporting polypeptide | Pharmacogenetics | Simvastatin | Repaglinide | Statin | Transporter | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Organic Anion Transporters, Sodium-Independent - genetics | Peptides - physiology | Humans | Liver - metabolism | Intestinal Absorption | Blood-Brain Barrier - metabolism | Genetic Variation | Organic Anion Transporters - genetics | Pharmaceutical Preparations - metabolism | Drug Interactions | Organic Anion Transporters - physiology | Pharmacokinetics | Solute Carrier Organic Anion Transporter Family Member 1b1 | Solute Carrier Organic Anion Transporter Family Member 1B3 | Organic Anion Transporters, Sodium-Independent - physiology | Index Medicus | Reviews
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2. Full Text Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug–Drug Interactions
by Karlgren, Maria and Vildhede, Anna and Norinder, Ulf and Wisniewski, Jacek R and Kimoto, Emi and Lai, Yurong and Haglund, Ulf and Artursson, Per
Journal of medicinal chemistry, ISSN 0022-2623, 05/2012, Volume 55, Issue 10, pp. 4740 - 4763
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Multivariate Analysis | Organic Anion Transporters, Sodium-Independent - genetics | Estradiol - analogs & derivatives | Organic Anion Transporters, Sodium-Independent - antagonists & inhibitors | Pyrroles - pharmacokinetics | Heptanoic Acids - pharmacokinetics | Humans | Structure-Activity Relationship | Organic Anion Transporters - metabolism | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Organic Anion Transporters - genetics | Drug Interactions | Protein Isoforms - metabolism | Transfection | Organic Anion Transporters, Sodium-Independent - metabolism | HEK293 Cells | Biological Transport - drug effects | Solute Carrier Organic Anion Transporter Family Member 1B3 | Organic Anion Transporters - antagonists & inhibitors | Liver - metabolism | Models, Molecular | Atorvastatin Calcium | Estradiol - pharmacokinetics | Estrone - analogs & derivatives | Least-Squares Analysis | Estrone - pharmacokinetics | In Vitro Techniques | Solute Carrier Organic Anion Transporter Family Member 1b1 | Protein Isoforms - antagonists & inhibitors | Index Medicus
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3. Full Text The drug transporter OAT3 (SLC22A8) and endogenous metabolite communication via the gut–liver– kidney axis
by Bush, Kevin T and Wu, Wei and Lun, Christina and Nigam, Sanjay K
The Journal of biological chemistry, ISSN 0021-9258, 09/2017, Volume 292, Issue 38, pp. 15789 - 15803
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Metabolomics | Organic Anion Transporters, Sodium-Independent - genetics | Organic Anion Transport Protein 1 - metabolism | Organic Anion Transporters, Sodium-Independent - deficiency | Liver - metabolism | Mice, Inbred C57BL | Gastrointestinal Microbiome | Substrate Specificity | Bile Acids and Salts - metabolism | Lipid Metabolism | Male | Intestines - metabolism | Gene Knockout Techniques | Amino Acids - metabolism | Kidney - metabolism | Animals | Intestines - microbiology | Diet | Energy Metabolism | Organic Anion Transporters, Sodium-Independent - metabolism | Ligands | Mice | Xenobiotics - metabolism | Index Medicus | kidney | renal physiology | organic anion | multidrug transporter | OAT3 | drug transport | uremic toxin | Metabolism | xenobiotic | kidney drug transport | solute carrier
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4. Full Text Bosentan Is a Substrate of Human OATP1B1 and OATP1B3: Inhibition of Hepatic Uptake as the Common Mechanism of Its Interactions with Cyclosporin A, Rifampicin, and Sildenafil
by Alexander Treiber and Ralph Schneiter and Stephanie Häusler and Bruno Stieger
Drug metabolism and disposition, ISSN 0090-9556, 08/2007, Volume 35, Issue 8, pp. 1400 - 1407
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Cytochrome P-450 CYP2C9 | Organic Anion Transporters, Sodium-Independent - genetics | Estradiol - analogs & derivatives | Organic Anion Transporters, Sodium-Independent - antagonists & inhibitors | Cricetulus | Cytochrome P-450 Enzyme Inhibitors | Cyclosporine - pharmacology | Cytochrome P-450 CYP3A | Humans | Warfarin - metabolism | Cytochrome P-450 Enzyme System - metabolism | Dehydroepiandrosterone Sulfate - metabolism | Sulfones - pharmacology | Organic Anion Transporters - metabolism | Pyrimidines - chemistry | Pyrimidines - metabolism | Sildenafil Citrate | Organic Anion Transporters - genetics | Bosentan | Drug Interactions | Organic Anion Transporters, Sodium-Independent - metabolism | Biological Transport - drug effects | Molecular Structure | Solute Carrier Organic Anion Transporter Family Member 1B3 | CHO Cells | Estradiol - metabolism | Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors | Cricetinae | Organic Anion Transporters - antagonists & inhibitors | Sulfonamides - chemistry | Purines - pharmacology | Enzyme Inhibitors - pharmacology | Piperazines - pharmacology | Sulfonamides - pharmacokinetics | Aryl Hydrocarbon Hydroxylases - metabolism | Animals | Estrone - analogs & derivatives | Estrone - metabolism | Sulfonamides - metabolism | Liver-Specific Organic Anion Transporter 1 | Rifampin - pharmacology | Index Medicus
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5. Renal Drug Transporters and Drug Interactions
by Ivanyuk, Anton and Livio, Françoise and Biollaz, Jérôme and Buclin, Thierry
Clinical pharmacokinetics, ISSN 0312-5963, 08/2017, Volume 56, Issue 8, pp. 825 - 892
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | ATP Binding Cassette Transporter, Subfamily G, Member 2 - metabolism | Renal Agents - pharmacokinetics | Humans | Male | Neoplasm Proteins - metabolism | Organic Anion Transporters - metabolism | Neoplasm Proteins - drug effects | Kidney - metabolism | Organic Anion Transporters, Sodium-Independent - metabolism | Organic Cation Transport Proteins - drug effects | Organic Anion Transporters, Sodium-Independent - drug effects | ATP Binding Cassette Transporter, Subfamily B - drug effects | Female | Biological Transport - drug effects | Organic Cation Transport Proteins - metabolism | Multidrug Resistance-Associated Proteins - drug effects | Renal Agents - therapeutic use | ATP Binding Cassette Transporter, Subfamily B - metabolism | Kidney - ultrastructure | ATP Binding Cassette Transporter, Subfamily G, Member 2 - drug effects | Animals | Drug Interactions - physiology | Kidney Tubules, Proximal - metabolism | Renal Agents - metabolism | Biological Transport - physiology | Multidrug Resistance-Associated Proteins - metabolism | Organic Anion Transporters - drug effects | Index Medicus
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