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Journal Article
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7652, pp. 48 - 53
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 494, Issue 7436, pp. 247 - 250
Journal Article
Nature, ISSN 0028-0836, 01/2019, Volume 565, Issue 7740, pp. 505 - 510
The increasing prevalence of diabetes has resulted in a global epidemic1. Diabetes is a major cause of blindness, kidney failure, heart attacks, stroke and... 
PLURIPOTENT STEM-CELLS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | EXPANSION | GENERATION | ANGIOPOIETIN-2 | MELLITUS | PERICYTES | LINES | Blood Vessels - growth & development | Basement Membrane - drug effects | Pericytes - drug effects | Blood Vessels - pathology | Humans | Pericytes - cytology | Hyperglycemia - complications | Venules - drug effects | Organoids - transplantation | Arteries - cytology | Basement Membrane - pathology | Intercellular Signaling Peptides and Proteins - metabolism | Diabetic Angiopathies - pathology | Inflammation Mediators - pharmacology | Diabetic Angiopathies - enzymology | Arterioles - cytology | Receptor, Notch3 - metabolism | Organoids - pathology | Pluripotent Stem Cells - cytology | Signal Transduction | Basement Membrane - cytology | Organoids - cytology | Arteries - drug effects | Venules - cytology | Arterioles - drug effects | Blood Vessels - cytology | Amyloid Precursor Protein Secretases - metabolism | Animals | Endothelial Cells - cytology | Models, Biological | Pluripotent Stem Cells - drug effects | Blood Vessels - drug effects | Organoids - drug effects | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | In Vitro Techniques | Endothelial Cells - drug effects | Type 2 diabetes | Blood vessels | Research | Diabetes | Diabetics | Heart attack | Stem cells | Blindness | Endothelium | Heart | Diabetic retinopathy | Epidemics | Regulators | Nuclear magnetic resonance--NMR | Transplants & implants | Arterioles | Stem cell transplantation | Blood | Arteries | Angiogenesis | Hyperglycemia | Vascular diseases | Organoids | Amputation | Heart diseases | Thickening | Stroke | Cytokines | Diabetes mellitus | Inflammation | Gene expression | Patients | Endothelial cells | Collagen | Renal failure | Pericytes | Microvasculature | Pluripotency | Structure-function relationships
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2015, Volume 112, Issue 40, pp. 12516 - 12521
Human pluripotent stem cell-based in vitro models that reflect human physiology have the potential to reduce the number of drug failures in clinical trials and... 
Organoid | Toxicology | Differentiation | Tissue engineering | Machine learning | toxicology | tissue engineering | DEVELOPMENTAL NEUROTOXICITY | differentiation | MULTIDISCIPLINARY SCIENCES | INVOLVEMENT | CLASSIFICATION | NEURODEGENERATION | machine learning | CANCER | organoid | IN-VITRO | MICROGLIA | GENE-EXPRESSION | SYSTEMS | BRAIN | Embryonic Stem Cells - metabolism | Microglia - metabolism | Embryonic Stem Cells - cytology | Humans | Brain - growth & development | Support Vector Machine | Neural Stem Cells - cytology | Xenobiotics - pharmacology | Brain - metabolism | Neurogenesis - genetics | Mesenchymal Stromal Cells - cytology | Xenobiotics - classification | Gene Expression Regulation, Developmental | Cell Differentiation | Neurogenesis - drug effects | Culture Media, Serum-Free - pharmacology | Gene Ontology | Polyethylene Glycols - pharmacology | Microglia - cytology | Mesenchymal Stromal Cells - drug effects | Brain - cytology | Pluripotent Stem Cells - cytology | Tissue Engineering - methods | Microglia - drug effects | Endothelial Cells - metabolism | Cells, Cultured | Neural Stem Cells - drug effects | Mesenchymal Stromal Cells - metabolism | Cell Communication - genetics | Macrophages - cytology | Pluripotent Stem Cells - metabolism | Macrophages - metabolism | Embryonic Stem Cells - drug effects | Endothelial Cells - cytology | Models, Biological | Pluripotent Stem Cells - drug effects | Cell Communication - drug effects | Macrophages - drug effects | Hydrogels - pharmacology | Neural Stem Cells - metabolism | Endothelial Cells - drug effects | Neurotoxicity | Stem cells | Gene expression | Biological assays | Bioinformatics | Artificial intelligence | Index Medicus | Biological Sciences
Journal Article
eLife, ISSN 2050-084X, 03/2015, Volume 2015, Issue 4, pp. 1 - 25
Recent breakthroughs in 3-dimensional (3D) organoid cultures for many organ systems have led to new physiologically complex in vitro models to study human... 
EXPRESSION PATTERNS | PROGENITOR CELLS | HUMAN AIRWAY EPITHELIUM | VENTRAL FOREGUT | BIOLOGY | BRANCHING MORPHOGENESIS | DEFINITIVE ENDODERM | EXTRACELLULAR-MATRIX | MOUSE LUNG | CLUSTER-ANALYSIS | BASAL-CELLS | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Humans | Gene Expression Profiling | Spheroids, Cellular - cytology | Lung - cytology | Cell Culture Techniques - methods | Cell Differentiation - genetics | Endoderm - cytology | Organoids - metabolism | Organoids - ultrastructure | Lung - metabolism | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - metabolism | Cell Line | Microscopy, Electron, Transmission | Reproducibility of Results | Pluripotent Stem Cells - cytology | Tissue Engineering - methods | Spheroids, Cellular - metabolism | Cells, Cultured | Organoids - cytology | Reverse Transcriptase Polymerase Chain Reaction | Endoderm - metabolism | Organogenesis | Pluripotent Stem Cells - metabolism | Microscopy, Confocal | Lung - embryology | Cluster analysis | Mesenchyme | Transcription | Developmental biology | Lung | Lung diseases | Fetuses | Embryo cells | Basal cells | Principal components analysis | Smooth muscle | Genomes | Epithelium | Ribonucleic acid--RNA | Spheroids | Children & youth | Respiratory tract | Hospitals | Organoids | Stem cells | Alveoli | Pluripotency | Foregut | Index Medicus
Journal Article
Nature: international weekly journal of science, ISSN 0028-0836, 12/2015, Volume 528, Issue 7583, pp. 560 - 564
Journal Article
Nature, ISSN 0028-0836, 06/2015, Volume 522, Issue 7555, pp. 173 - 178
Journal Article