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1. Full Text Hybrid nanoparticles for combination therapy of cancer
by He, Chunbai and Lu, Jianqin and Lin, Wenbin
Journal of controlled release, ISSN 0168-3659, 12/2015, Volume 219, pp. 224 - 236
Combination therapy of cancer | Co-delivery | Synergistic effect | Hybrid nanoparticle | Pharmacology & Pharmacy | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Polymers - administration & dosage | Gold - administration & dosage | Nanoparticles - chemistry | Humans | Ferric Compounds - administration & dosage | Ferric Compounds - chemistry | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Drug Delivery Systems | Organosilicon Compounds - administration & dosage | Polymers - therapeutic use | Organosilicon Compounds - therapeutic use | Nanoparticles - therapeutic use | Organometallic Compounds - therapeutic use | Gold - chemistry | Antineoplastic Agents - chemistry | Neoplasms - drug therapy | Animals | Organosilicon Compounds - chemistry | Ferric Compounds - therapeutic use | Gold - therapeutic use | Organometallic Compounds - chemistry | Polymers - chemistry | Nanoparticles - administration & dosage | Drug Combinations | Organometallic Compounds - administration & dosage | Nanoparticles | Drugs | Drug delivery systems | Chemotherapy | Analysis | Permeability | Health aspects | Cancer | Vehicles | Drug resistance | Photochemotherapy | Index Medicus | co-delivery | combination therapy of cancer | synergistic effect
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2. Full Text Histology and Gadolinium Distribution in the Rodent Brain After the Administration of Cumulative High Doses of Linear and Macrocyclic Gadolinium-Based Contrast Agents
by Lohrke, Jessica and Frisk, Anna-Lena and Frenzel, Thomas and Schöckel, Laura and Rosenbruch, Martin and Jost, Gregor and Lenhard, Diana Constanze and Sieber, Martin A and Nischwitz, Volker and Küppers, Astrid and Pietsch, Hubertus
Investigative radiology, ISSN 0020-9996, 03/2017, Volume 52, Issue 6, pp. 324 - 333
Gadodiamide | Gadobutrol | Gadolinium retention | MRI | Contrast agent | Gadoteridol | Globus pallidus | Histology | Dentate nucleus | Gadopentetate dimeglumine | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Gadolinium - administration & dosage | Injections, Intravenous | Rats, Wistar | Gadolinium - pharmacokinetics | Contrast Media - pharmacokinetics | Male | Muscle, Skeletal - metabolism | Bone and Bones - drug effects | Brain - metabolism | Dose-Response Relationship, Drug | Contrast Media - adverse effects | Bone and Bones - metabolism | Contrast Media - administration & dosage | Mass Spectrometry | Muscle, Skeletal - drug effects | Brain - ultrastructure | Gadolinium DTPA - pharmacokinetics | Models, Animal | Gadolinium DTPA - administration & dosage | Retrospective Studies | Gadolinium DTPA - adverse effects | Heterocyclic Compounds - administration & dosage | Organometallic Compounds - adverse effects | Rodentia | Organometallic Compounds - pharmacokinetics | Rats | Gadolinium - adverse effects | Brain - drug effects | Animals | Heterocyclic Compounds - adverse effects | Skin - ultrastructure | Heterocyclic Compounds - pharmacokinetics | Skin - drug effects | Organometallic Compounds - administration & dosage | Index Medicus | gadolinium retention | histology | gadopentetate dimeglumine | gadobutrol | Original | globus pallidus | gadoteridol | contrast agent | dentate nucleus | gadodiamide
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3. Full Text Comparison of gadolinium concentrations within multiple rat organs after intravenous administration of linear versus macrocyclic gadolinium chelates
by McDonald, Robert J and McDonald, Jennifer S and Dai, Daying and Schroeder, Dana and Jentoft, Mark E and Murray, David L and Kadirvel, Ramanathan and Eckel, Laurence J and Kallmes, David F
Radiology, ISSN 0033-8419, 11/2017, Volume 285, Issue 2, pp. 536 - 545
Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Gadolinium - administration & dosage | Rats, Wistar | Heterocyclic Compounds - administration & dosage | Gadolinium - pharmacokinetics | Contrast Media - pharmacokinetics | Organometallic Compounds - pharmacokinetics | Rats | Male | Contrast Media - analysis | Liver - chemistry | Spleen - chemistry | Tissue Distribution | Magnetic Resonance Imaging | Administration, Intravenous | Animals | Contrast Media - administration & dosage | Gadolinium - analysis | Heterocyclic Compounds - pharmacokinetics | Cerebellum - chemistry | Retrospective Studies | Organometallic Compounds - administration & dosage | Index Medicus | Abridged Index Medicus
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4. Full Text Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy
by Leijen, Suzanne and Burgers, Sjaak A and Baas, Paul and Pluim, Dick and Tibben, Matthijs and van Werkhoven, Erik and Alessio, Enzo and Sava, Gianni and Beijnen, Jos H and Schellens, Jan H. M
Investigational new drugs, ISSN 0167-6997, 2015, Volume 33, Issue 1, pp. 201 - 214
NAMI-A | Ruthenium | Phase I | Medicine & Public Health | Gemcitabine | Non-small cell lung cancer | Oncology | Phase II | Pharmacology/Toxicology | Clinical study | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Lung Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Ruthenium - administration & dosage | Deoxycytidine - pharmacokinetics | Ruthenium - adverse effects | Adult | Deoxycytidine - adverse effects | Dimethyl Sulfoxide - administration & dosage | Female | Ruthenium - blood | Dimethyl Sulfoxide - adverse effects | Organometallic Compounds - adverse effects | Deoxycytidine - administration & dosage | Carcinoma, Non-Small-Cell Lung - metabolism | Organometallic Compounds - pharmacokinetics | Treatment Outcome | Ruthenium - pharmacokinetics | Maximum Tolerated Dose | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Dimethyl Sulfoxide - analogs & derivatives | Deoxycytidine - analogs & derivatives | Dimethyl Sulfoxide - pharmacokinetics | Organometallic Compounds - administration & dosage | Complications and side effects | Dosage and administration | Research | Lung cancer, Non-small cell | Drug therapy | Studies | Clinical trials | Lung cancer | Pharmaceutical sciences | Clinical outcomes | Index Medicus
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5. Full Text Gadolinium brain deposition after macrocyclic gadolinium administration: A pediatric case-control study
by Tibussek, Daniel and Rademacher, Christin and Caspers, Julian and Turowski, Bernd and Schaper, Jörg and Antoch, Gerald and Klee, Dirk
Radiology, ISSN 0033-8419, 10/2017, Volume 285, Issue 1, pp. 223 - 230
Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Gadolinium - administration & dosage | Meglumine - metabolism | Brain - diagnostic imaging | Gadolinium - pharmacology | Meglumine - therapeutic use | Humans | Child, Preschool | Male | Case-Control Studies | Brain - metabolism | Contrast Media - pharmacology | Contrast Media - administration & dosage | Organometallic Compounds - therapeutic use | Contrast Media - therapeutic use | Female | Retrospective Studies | Child | Gadolinium - therapeutic use | Brain - drug effects | Magnetic Resonance Imaging | Administration, Intravenous | Meglumine - pharmacology | Organometallic Compounds - metabolism | Meglumine - administration & dosage | Adolescent | Brain - pathology | Contrast Media - metabolism | Gadolinium - metabolism | Organometallic Compounds - pharmacology | Organometallic Compounds - administration & dosage | Index Medicus | Abridged Index Medicus
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6. Full Text Postsynthetic Modifications of Iron-Carboxylate Nanoscale Metal−Organic Frameworks for Imaging and Drug Delivery
by Taylor-Pashow, Kathryn M. L and Rocca, Joseph Della and Xie, Zhigang and Tran, Sylvie and Lin, Wenbin
Journal of the American Chemical Society, ISSN 0002-7863, 10/2009, Volume 131, Issue 40, pp. 14261 - 14263
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Boron Compounds - chemistry | Succinates - chemistry | Phthalic Acids - chemistry | Humans | Metal Nanoparticles - chemistry | Models, Molecular | Ferric Compounds - administration & dosage | Ferric Compounds - chemistry | Antineoplastic Agents - administration & dosage | Antineoplastic Agents - chemistry | HT29 Cells | Organoplatinum Compounds - administration & dosage | Succinates - administration & dosage | Metal Nanoparticles - administration & dosage | X-Ray Diffraction | Carboxylic Acids - chemistry | Contrast Media - administration & dosage | Contrast Media - chemistry | Carboxylic Acids - administration & dosage | Drug Delivery Systems - methods | Organoplatinum Compounds - chemistry | Colon cancer | Iron compounds | Optical properties | Organometallic compounds | Diagnostic imaging | Research | Chemical properties | Structure | Contrast media | Index Medicus
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7. Full Text Comparison of efficacy of pharmacological treatments for chronic idiopathic constipation: a systematic review and network meta-analysis
by Nelson, Alfred D and Camilleri, Michael and Chirapongsathorn, Sakkarin and Vijayvargiya, Priya and Valentin, Nelson and Shin, Andrea and Erwin, Patricia J and Wang, Zhen and Murad, M Hassan
Gut, ISSN 0017-5749, 09/2017, Volume 66, Issue 9, pp. 1611 - 1622
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Picolines - administration & dosage | Bisacodyl - administration & dosage | Organometallic Compounds - adverse effects | Azabicyclo Compounds - administration & dosage | Defecation - drug effects | Humans | Gastrointestinal Agents - administration & dosage | Benzofurans - administration & dosage | Treatment Outcome | Bisacodyl - adverse effects | Constipation - physiopathology | Drug Monitoring - methods | Benzofurans - adverse effects | Picolines - adverse effects | Randomized Controlled Trials as Topic | Citrates - administration & dosage | Constipation - diagnosis | Constipation - drug therapy | Gastrointestinal Agents - adverse effects | Citrates - adverse effects | Chronic Disease | Azabicyclo Compounds - adverse effects | Organometallic Compounds - administration & dosage | Causes of | Usage | Research | Drug therapy | Constipation | Patient outcomes | Drugs | Polyethylene | Clinical trials | Systematic review | Data processing | Meta-analysis | Sodium | Polyethylene glycol | Intestine | Gastroenterology | Irritable bowel syndrome | Electrolytes | Laxatives | Bayesian analysis | Index Medicus | Abridged Index Medicus
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8. Full Text Targeted alpha-radionuclide therapy of functionally critically located gliomas with 213Bi-DOTA-[Thi8,Met(O2)11]-substance P: a pilot trial
by Cordier, D and Forrer, F and Bruchertseifer, F and Morgenstern, A and Apostolidis, C and Good, S and Müller-Brand, J and Mäcke, H and Reubi, J C and Merlo, A
European journal of nuclear medicine and molecular imaging, ISSN 1619-7070, 7/2010, Volume 37, Issue 7, pp. 1335 - 1344
Medicine & Public Health | Glioma | Substance P | Targeted therapy | Orthopedics | Oncology | Nuclear Medicine | Cardiology | Imaging / Radiology | 213 Bi | Heterocyclic Compounds, 1-Ring - pharmacokinetics | Organometallic Compounds - adverse effects | Humans | Middle Aged | Organometallic Compounds - pharmacokinetics | Treatment Outcome | Substance P - therapeutic use | Alpha Particles - therapeutic use | Glioma - radiotherapy | Substance P - adverse effects | Feasibility Studies | Glioma - metabolism | Heterocyclic Compounds, 1-Ring - administration & dosage | Injections | Pilot Projects | Heterocyclic Compounds, 1-Ring - adverse effects | Heterocyclic Compounds, 1-Ring - therapeutic use | Organometallic Compounds - therapeutic use | Adult | Substance P - analogs & derivatives | Substance P - pharmacokinetics | Organometallic Compounds - administration & dosage | Substance P - administration & dosage | Brain | Radiation therapy | Tumors | Index Medicus
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9. Full Text The mitochondrial apoptotic pathway is induced by Cu(II) antineoplastic compounds (Casiopeínas®) in SK-N-SH neuroblastoma cells after short exposure times
by García-Ramos, Juan Carlos and García-Ramos, Juan Carlos and Gutiérrez, Anllely Grizett and Gutiérrez, Anllely Grizett and Vázquez-Aguirre, Adriana and Vázquez-Aguirre, Adriana and Toledano-Magaña, Yanis and Toledano-Magaña, Yanis and Alonso-Sáenz, Ana Luisa and Alonso-Sáenz, Ana Luisa and Gómez-Vidales, Virginia and Gómez-Vidales, Virginia and Flores-Alamo, Marcos and Flores-Alamo, Marcos and Mejía, Carmen and Mejía, Carmen and Ruiz-Azuara, Lena and Ruiz-Azuara, Lena
Biometals, ISSN 0966-0844, 2/2017, Volume 30, Issue 1, pp. 43 - 58
Life Sciences | Biochemistry, general | Reactive oxygen species | Neuroblastome SK-N-SH | Microbiology | Casiopeínas | Antitumour copper(II) compounds | Lymphocytes cytotoxicity | Plant Physiology | Pharmacology/Toxicology | Medicine/Public Health, general | Cell Biology | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Reactive Oxygen Species - metabolism | Oxidation-Reduction | Apoptosis - drug effects | Humans | Antineoplastic Agents - administration & dosage | Mitochondria - drug effects | Mitochondria - pathology | Antineoplastic Agents - chemistry | Membrane Potential, Mitochondrial - drug effects | Cisplatin - administration & dosage | Cisplatin - chemistry | Copper - chemistry | Neuroblastoma - drug therapy | Cell Line, Tumor | Organometallic Compounds - chemistry | Neuroblastoma - pathology | Organometallic Compounds - administration & dosage | Oxidative stress | Mitochondria | Copper | Apoptosis | Tumors | Index Medicus | Molecular structure | Pathways | Antiproliferatives | Sulfur | Coordination compounds | Paediatrics | Glutathione
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