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Neurotoxicology, ISSN 0161-813X, 2007, Volume 28, Issue 6, pp. 1208 - 1219
The present study elucidates a possible mechanism by which chronic organophosphate exposure (dichlorvos 6 mg/kg bw, s.c. for 12 weeks) causes neuronal... 
Mitochondrial oxidative stress | Dichlorvos | Mitochondria electron transport chain | Cytochrome c release | Calcium homeostasis | Apoptosis | NERVOUS-SYSTEM | mitochondrial oxidative stress | mitochondria electron transport chain | apoptosis | calcium homeostasis | NEUROSCIENCES | dichlorvos | DAMAGE | PESTICIDES | TRANSPORT | CHLORPYRIFOS | GLUTATHIONE | DNA | ORGANOPHOSPHATE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | TISSUES | cytochrome c release | SUPEROXIDE-DISMUTASE | Mitochondria - enzymology | Reactive Oxygen Species - metabolism | Rats, Wistar | Apoptosis - drug effects | Calcium - metabolism | DNA, Mitochondrial - drug effects | Glutathione - metabolism | Caspase 3 - metabolism | Brain - enzymology | Male | Protein Carbonylation - drug effects | Electron Transport Complex I - metabolism | Nerve Degeneration - chemically induced | Nerve Degeneration - metabolism | Electron Transport Complex IV - metabolism | Brain - metabolism | Dose-Response Relationship, Drug | Time Factors | Lipid Peroxidation - drug effects | Neurons - metabolism | Neurons - drug effects | Deoxyguanosine - analogs & derivatives | Superoxide Dismutase - metabolism | DNA, Mitochondrial - metabolism | Cytochromes c - metabolism | Rats | Mitochondria - metabolism | Mitochondria - drug effects | Nerve Degeneration - pathology | Brain - drug effects | Dichlorvos - toxicity | Animals | Electron Transport Complex II - metabolism | Neurons - enzymology | Brain - pathology | Deoxyguanosine - metabolism | Enzyme Activation | Oxidative Stress - drug effects | Insecticides - toxicity | Energy Metabolism - drug effects | Index Medicus
Journal Article
Journal Article
Free Radical Research, ISSN 1071-5762, 04/2011, Volume 45, Issue 4, pp. 417 - 430
Journal Article
Environmental Toxicology and Pharmacology, ISSN 1382-6689, 09/2017, Volume 54, pp. 99 - 104
The current study was performed to investigate the ameliorating effect of dietary supplementation of 0.5 and 1% (SP) diet against the sub-acute toxicity of... 
Oxidative stress | Spirulina | Organophosphate | Nile tilapia | Antioxidant | Diazinon | ARTHROSPIRA-PLATENSIS | LIPID-PEROXIDATION | ANTIOXIDANT ENZYMES | SERUM | FRESH-WATER FISH | CYPRINUS-CARPIO | ALKALINE-PHOSPHATASE ACTIVITY | ENVIRONMENTAL SCIENCES | LIVER | PHARMACOLOGY & PHARMACY | TOXICOLOGY | CLARIAS-BATRACHUS | STRESS | Glutathione - metabolism | Alkaline Phosphatase - metabolism | Male | Creatinine - metabolism | Gills - drug effects | Kidney - metabolism | Liver - drug effects | Urea - metabolism | Superoxide Dismutase - metabolism | Malondialdehyde - metabolism | Kidney - drug effects | Uric Acid - metabolism | Diazinon - toxicity | Liver - metabolism | Gills - metabolism | Antioxidants - pharmacology | Aspartate Aminotransferases - metabolism | Cichlids - metabolism | Catalase - metabolism | Animals | Diet | Alanine Transaminase - metabolism | Oxidative Stress - drug effects | Insecticides - toxicity | Antioxidants | Urea | Phosphatases | Liver | Fishes | Dietary supplements | Albumin | Superoxide | Glucose | Uric acid | Dextrose | Blood proteins | Alkaline phosphatase | Toxicity | Transaminase | Lipid peroxidation | Insecticides | Superoxide dismutase | Impact analysis | Proteins | Catalase | Aspartate transaminase | Fish | Peroxidase | Supplementation | Damage | Glutathione | Peroxidation | Creatinine | Glutathione peroxidase | Alanine | Kidneys | Markers | Gills | Tilapia | Serum albumin | Malondialdehyde | Cholesterol | Studies | Oreochromis niloticus | Globulins | Spirulina platensis | Biomarkers | Alanine transaminase | Acute toxicity | Biochemical markers | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, pp. 21827 - 21827
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 12/2017, Volume 337, pp. 67 - 75
The prevalence of obesity is increasing at an alarming rate in the United States with 36.5% of adults being classified as obese. Compared to normal... 
Chlorpyrifos | Organophosphate | Endocannabinoid | Acetylcholinesterase | Carboxylesterase | High-fat diet | TRIACYLGLYCEROL HYDROLASE | PARAOXONASE-1 RESPONSE | NATIONAL-HEALTH | PERSISTENT ORGANIC POLLUTANTS | RAT-LIVER MICROSOMES | NONDIABETIC ADULTS | SERUM CONCENTRATIONS | DECREASES BLOOD-LIPIDS | INSULIN-RESISTANCE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | HEPATIC STEATOSIS | Endocannabinoids - metabolism | Activation, Metabolic | Cholinesterase Inhibitors - toxicity | Liver - enzymology | Male | Obesity - blood | Chlorpyrifos - metabolism | Monoacylglycerol Lipases - metabolism | Arachidonic Acids - metabolism | Cholinesterase Inhibitors - metabolism | Liver - drug effects | Diet, High-Fat | Erythrocytes - enzymology | Hepatocytes - drug effects | Disease Models, Animal | Amidohydrolases - metabolism | Mice, Inbred C57BL | Cells, Cultured | Glycerides - metabolism | Polyunsaturated Alkamides - metabolism | Rats, Sprague-Dawley | GPI-Linked Proteins - metabolism | Erythrocytes - drug effects | Obesity - metabolism | Hydrolysis | Phenotype | Animals | Insecticides - metabolism | Chlorpyrifos - toxicity | Obesity - enzymology | Insecticides - toxicity | Acetylcholinesterase - metabolism | Carboxylic Ester Hydrolases - metabolism | Hepatocytes - enzymology | Obesity | Enzyme inhibitors | Analysis | Insecticides | Mice | Xenobiotics | Fatty acids | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, pp. e0149613 - e0149613
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 10/2015, Volume 288, Issue 1, pp. 114 - 120
Parathion, a widely used organophosphate insecticide, is considered a high priority chemical threat. Parathion toxicity is dependent on its metabolism by the... 
Parathion | Redox cycling | Menadione | Cytochrome P450 system | Cytochrome P450 reductase | ACTIVATION | MECHANISMS | ACUTE TOXICITY | DELETION | GESTATIONAL EXPOSURE | CHLORPYRIFOS | LIVER | PURIFICATION | REDUCTASE | PHARMACOLOGY & PHARMACY | P450 | TOXICOLOGY | Activation, Metabolic | Organophosphate Poisoning - enzymology | Cholinesterase Inhibitors - toxicity | Liver - enzymology | Parathion - toxicity | Humans | Rats, Long-Evans | Cytochrome P-450 Enzyme System - metabolism | Cytochrome P-450 Enzyme Inhibitors - metabolism | Parathion - metabolism | Dose-Response Relationship, Drug | Paraoxon - toxicity | Cholinesterase Inhibitors - metabolism | Liver - drug effects | Paraoxon - metabolism | Time Factors | Microsomes, Liver - drug effects | Female | Microsomes, Liver - enzymology | NADP - metabolism | Cytoprotection | Disease Models, Animal | Recombinant Proteins - metabolism | Oxidation-Reduction | Organophosphate Poisoning - prevention & control | GPI-Linked Proteins - metabolism | Vitamin K 3 - pharmacology | Vitamin K 3 - metabolism | Cytochrome P-450 Enzyme Inhibitors - pharmacology | Animals | Insecticides - metabolism | Organophosphate Poisoning - etiology | Insecticides - toxicity | Acetylcholinesterase - metabolism | Sulfites | Metabolites | Cytochrome P-450 | Physiological aspects | Insecticides | Poisoning | Vitamins | Phosphates | Liver | Acetylcholine | Index Medicus | CHOLINESTERASE | METABOLITES | ACETYLCHOLINE | RATS | SYMPTOMS | TOXICITY | 60 APPLIED LIFE SCIENCES | PARATHION | CYTOCHROMES | INHIBITION | METABOLISM | MICROSOMES | PHOSPHATES | VITAMINS | RECEPTORS | BRAIN | OXIDOREDUCTASES | redox cycling | cytochrome P450 reductase | parathion | menadione | cytochrome P450 system
Journal Article