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Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 02/2012, Volume 340, Issue 2, pp. 422 - 432
Phospho-nonsteroidal anti-inflammatory drugs (phospho-NSAIDs) are novel NSAID derivatives with improved anticancer activity and reduced side effects in... 
Organophosphates - metabolism | Indomethacin - analogs & derivatives | Naproxen - analogs & derivatives | Humans | Naproxen - pharmacology | Phenylglyoxal - analogs & derivatives | Indomethacin - metabolism | Valproic Acid - analogs & derivatives | Anti-Inflammatory Agents, Non-Steroidal - blood | Naproxen - metabolism | Organophosphorus Compounds - metabolism | Valproic Acid - pharmacology | Ibuprofen - analogs & derivatives | Aspirin - metabolism | Nitrophenols - therapeutic use | Organophosphorus Compounds - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Aspirin - pharmacology | Carboxylesterase - antagonists & inhibitors | Valproic Acid - metabolism | Cell Survival - drug effects | Organophosphates - blood | Enzyme Inhibitors - pharmacology | Organophosphorus Compounds - therapeutic use | Stomach Neoplasms - drug therapy | Ibuprofen - metabolism | Indomethacin - pharmacology | Aspirin - analogs & derivatives | Mice, Nude | Carboxylesterase - genetics | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Kinetics | Organophosphates - therapeutic use | Stomach Neoplasms - pathology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Sulindac - metabolism | Transfection | Nitrophenols - pharmacology | HEK293 Cells | Inhibitory Concentration 50 | Female | Sulindac - blood | Carboxylic Ester Hydrolases - genetics | Carboxylic Ester Hydrolases - antagonists & inhibitors | Ibuprofen - pharmacology | Phenylglyoxal - pharmacology | Sulindac - therapeutic use | Carboxylesterase - metabolism | Hydrolysis | Organophosphates - pharmacology | Xenograft Model Antitumor Assays | Sulindac - analogs & derivatives | Drug Therapy, Combination - methods | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Drug Interactions - physiology | Organophosphorus Compounds - blood | Sulindac - pharmacology | Carboxylic Ester Hydrolases - metabolism | Index Medicus | Metabolism, Transport, and Pharmacogenomics
Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 09/2013, Volume 57, Issue 9, pp. 4172 - 4180
Journal Article
Journal Article
FEBS Journal, ISSN 1742-464X, 12/2015, Volume 282, Issue 24, pp. 4747 - 4765
Renal cell carcinoma ( RCC ) is resistant to traditional cancer therapies, and metastatic RCC (mRCC) is incurable. The shortcomings in current therapeutic... 
apoptosis | triptolide | renal cell carcinoma | TRAIL | death receptor | HEAT-SHOCK-PROTEIN-70 INHIBITS APOPTOSIS | DENDRITIC CELLS | (TRAIL)-INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTI-DR5 ANTIBODY THERAPY | HEAT-SHOCK PROTEINS | TUMOR-NECROSIS-FACTOR | APOPTOSIS-INDUCING LIGAND | IN-VIVO | NF-KAPPA-B | PANCREATIC-CANCER CELLS | Recombinant Proteins - therapeutic use | Neoplasm Transplantation | Antineoplastic Combined Chemotherapy Protocols - chemistry | Apoptosis - drug effects | Receptors, TNF-Related Apoptosis-Inducing Ligand - agonists | Humans | Organophosphates - therapeutic use | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Kidney Neoplasms - metabolism | Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Epoxy Compounds - pharmacology | TNF-Related Apoptosis-Inducing Ligand - pharmacology | TNF-Related Apoptosis-Inducing Ligand - agonists | Female | Antineoplastic Agents - pharmacology | Antineoplastic Agents, Phytogenic - therapeutic use | Carcinoma, Renal Cell - drug therapy | Antibodies, Monoclonal - chemistry | Diterpenes - pharmacology | Epoxy Compounds - therapeutic use | Diterpenes - therapeutic use | Phenanthrenes - therapeutic use | Specific Pathogen-Free Organisms | Carcinoma, Renal Cell - pathology | Antibodies, Monoclonal - pharmacology | Recombinant Proteins - chemistry | Recombinant Proteins - pharmacology | Antineoplastic Agents - chemistry | TNF-Related Apoptosis-Inducing Ligand - therapeutic use | Drug Synergism | Organophosphates - pharmacology | Carcinoma, Renal Cell - metabolism | Phenanthrenes - pharmacology | Animals | Tumor Burden - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Survival Analysis | Cell Line, Tumor | Kidney Neoplasms - pathology | Mice | Mice, Inbred BALB C | Prodrugs - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacology | Kidney Neoplasms - drug therapy | Prodrugs - pharmacology | TNF-Related Apoptosis-Inducing Ligand - genetics | Heat shock proteins | Carcinoma, Renal cell | Rodents | Tumors | Apoptosis | Index Medicus
Journal Article
Journal Article
Annual review of pharmacology and toxicology, ISSN 0362-1642, 01/2019, Volume 59, Issue 1, pp. 341 - 360
Organophosphorus insecticide self-poisoning is a major global health problem, killing over 100,000 people annually. It is a complex multi-organ condition,... 
organophosphate | insecticide | highly hazardous pesticides | suicide | OXIME THERAPY | NERVE AGENT | N-ACETYLCYSTEINE | TOXICITY | BOLUS INJECTION | CARBAMATE PESTICIDE | PHARMACOLOGY & PHARMACY | AGENT-INDUCED SEIZURES | HUMAN LIVER | PRALIDOXIME | TOXICOLOGY | RESPIRATORY-FAILURE
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2010, Volume 30, Issue 21, pp. 7300 - 7309
Lysophosphatidic acid (LPA) is a membrane-derived lysophospholipid that can induce pleomorphic effects in neural progenitor cells (NPCs) from the cerebral... 
NEOCORTICAL VENTRICULAR ZONE | NEURONAL MIGRATION | PROGENITOR CELLS | NERVOUS-SYSTEM | NMDA RECEPTORS | PROTEIN-COUPLED RECEPTOR | EDG-FAMILY | DEVELOPING CEREBRAL-CORTEX | CA2+ TRANSIENTS | NEUROSCIENCES | MORPHOLOGICAL-CHANGES | Propionates - pharmacology | Calcium - metabolism | Embryo, Mammalian | Calcium Signaling - physiology | Gene Expression Regulation, Developmental - genetics | Neurons - cytology | RNA, Messenger - metabolism | Cerebral Cortex - cytology | Dose-Response Relationship, Drug | Intracellular Signaling Peptides and Proteins - deficiency | Neurogenesis - genetics | Membrane Proteins - deficiency | Membrane Proteins - physiology | Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology | Lysophospholipids - pharmacology | Neurons - physiology | Female | Neurogenesis - drug effects | Membrane Proteins - classification | Cadmium Chloride - pharmacology | Neurons - drug effects | Nickel - pharmacology | Pertussis Toxin - pharmacology | Glutamic Acid - pharmacology | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation, Developmental - drug effects | Intracellular Signaling Peptides and Proteins - classification | Mice, Knockout | Isoxazoles - pharmacology | Nerve Tissue Proteins - metabolism | Organophosphates - pharmacology | Pregnancy | Sphingosine - pharmacology | Extracellular Fluid - metabolism | Sphingosine - analogs & derivatives | Animals | Membrane Proteins - antagonists & inhibitors | Neurogenesis - physiology | Thapsigargin - pharmacology | Mice | Pyridines - pharmacology | Calcium Signaling - genetics | Intracellular Signaling Peptides and Proteins - physiology | Index Medicus
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 2017, Volume 72, Issue suppl_2, pp. ii48 - ii53
Journal Article