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1. Full Text Ternary toxicological interactions of insecticides, herbicides, and a heavy metal on the earthworm Eisenia fetida
by Wang, Qiang and Wang, Yanhua and Chen, Chen and Qian, Yongzhong and Zhao, Xueping
Journal of Hazardous Materials, ISSN 0304-3894, 03/2015, Volume 284, pp. 233 - 240
The combined toxicities of five insecticides (chlorpyrifos, avermectin, imidacloprid, λ-cyhalothrin, and phoxim), two herbicides (atrazine and butachlor), and... 
Combination index | Insecticide | Eisenia fetida | Acute mixture toxicity | Herbicide | Heavy metal | JOINT ALGAL TOXICITY | MIXTURE TOXICITY | ORGANOPHOSPHATE INSECTICIDES | AQUATIC ENVIRONMENT | ATRAZINE | ENVIRONMENTAL SCIENCES | ENGINEERING, CIVIL | CAENORHABDITIS-ELEGANS | BINARY-MIXTURES | ENGINEERING, ENVIRONMENTAL | CHEMICALS | DAPHNIA-MAGNA | PERFLUOROOCTANE SULFONIC-ACID | Nitriles - toxicity | Pyrethrins - toxicity | Cadmium - toxicity | Nitro Compounds - toxicity | Soil Pollutants - chemistry | Cadmium - pharmacology | Neonicotinoids | Herbicides - toxicity | Soil Pollutants - analysis | Animals | Organothiophosphorus Compounds - toxicity | Atrazine - toxicity | Ivermectin - toxicity | Acetanilides - toxicity | Oligochaeta - drug effects | Chlorpyrifos - toxicity | Ivermectin - analogs & derivatives | Toxicity Tests - methods | Imidazoles - toxicity | Metals, Heavy - chemistry | Insecticides - toxicity | Herbicides | Insecticides | Index Medicus | Additives | Toxicity | Interactive | Mathematical models | Imidacloprid | Heavy metals
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2. Full Text Chronic toxicity of clothianidin, imidacloprid, chlorpyrifos, and dimethoate to Apis mellifera L. larvae reared in vitro
by Dai, Pingli and Jack, Cameron J and Mortensen, Ashley N and Bustamante, Tomas A and Bloomquist, Jeffrey R and Ellis, James D
Pest Management Science, ISSN 1526-498X, 01/2019, Volume 75, Issue 1, pp. 29 - 36
This paper tests the effects of chronic exposure to two neonicotinoids (clothianidin and imidacloprid) and two organophosphates (chlorpyrifos and dimethoate)... 
Apis mellifera | dimethoate | clothianidin | larvae | chlorpyrifos | imidacloprid | HONEY | AGRONOMY | POLLEN | RISK | ENTOMOLOGY | BEES | PESTICIDES | POLLINATORS | NEONICOTINOID INSECTICIDES | EXPOSURE | LEARNING PERFORMANCES | Nitro Compounds - toxicity | Bees - growth & development | Neonicotinoids - toxicity | Dimethoate - toxicity | Thiazoles - toxicity | Toxicity Tests, Chronic | Animals | Larva - drug effects | Larva - growth & development | Guanidines - toxicity | Bees - drug effects | Chlorpyrifos - toxicity | In Vitro Techniques | Insecticides - toxicity | Organophosphates - toxicity | Chemical industry | Herbicides | Pesticides industry | Honeybee | Enzyme inhibitors | Analysis | Information management | Bees | Chlorpyrifos | Larvae | Nectar | Solvents | Chronic toxicity | Toxicity | Pesticides | Insecticides | Survival | Weight | Organophosphates | Chronic exposure | Organic chemistry | Honey | Diet | Pollen | Imidacloprid | Dimethoate | Pesticide toxicity | Acetone | Acute toxicity | Index Medicus
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3. Full Text Toxic effects of pesticide mixtures at a molecular level: Their relevance to human health
by Hernández, Antonio F and Parrón, Tesifón and Tsatsakis, Aristidis M and Requena, Mar and Alarcón, Raquel and López-Guarnido, Olga
Toxicology, ISSN 0300-483X, 2012, Volume 307, pp. 136 - 145
Highlights ► Toxic effects of pesticide mixtures can be independent, dose addition or interaction. ► Metabolic interactions involve inhibition or induction of... 
Emergency | Potentiation | Addition | Antagonism | Pesticide interactions | Synergism | HUMAN CYTOCHROME-P450 | SYNERGISTIC TOXICITY | PYRIDOSTIGMINE BROMIDE | MALATHION | PHARMACOLOGY & PHARMACY | HUMAN LIVER | TOXICOLOGY | INDUCED DELAYED POLYNEUROPATHY | RISK-ASSESSMENT | INSECTICIDES | EXPOSURE | RURAL-POPULATION | Hydrocarbons, Chlorinated - toxicity | Humans | Herbicides - toxicity | Pesticides - antagonists & inhibitors | Triazines - toxicity | Endocrine Disruptors - toxicity | Drug Synergism | Drug Interactions | Pesticides - toxicity | Imidazoles - toxicity | Organophosphate Poisoning - etiology | Carbaryl - toxicity | Carbamates - toxicity | Pesticides - pharmacology | Index Medicus
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4. Full Text Joint acute toxicity of the herbicide butachlor and three insecticides to the terrestrial earthworm, Eisenia fetida
by Wang, Yanhua and Cang, Tao and Yu, Ruixian and Wu, Shenggan and Liu, Xinju and Chen, Chen and Wang, Qiang and Cai, Leiming
Environmental Science and Pollution Research, ISSN 0944-1344, 6/2016, Volume 23, Issue 12, pp. 11766 - 11776
The herbicide butachlor and three insecticides phoxim, chlorpyrifos, and lambda-cyhalotrhin are widely used pesticides with different modes of action. As most... 
Environment, general | Environmental Health | Ecotoxicology | Pesticide | Ecotoxicity | Combined toxicity | Environment | Waste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution | Soil organism | Environmental Chemistry | Atmospheric Protection/Air Quality Control/Air Pollution | SOUTH-AFRICA | FRANKLINIELLA-OCCIDENTALIS PERGANDE | ATRAZINE | PESTICIDES | ENVIRONMENTAL SCIENCES | BINARY-MIXTURES | CHLORPYRIFOS | SOIL INVERTEBRATES | CHIRONOMUS-TENTANS DIPTERA | ORGANOPHOSPHATE | RISK-ASSESSMENT | Nitriles - toxicity | Pyrethrins - toxicity | Herbicides - toxicity | Toxicity Tests, Acute | Soil Pollutants - toxicity | Animals | Drug Interactions | Organothiophosphorus Compounds - toxicity | Pesticides - toxicity | Acetanilides - toxicity | Oligochaeta - drug effects | Soil - chemistry | Chlorpyrifos - toxicity | Insecticides - toxicity | Toxicity Tests | Insecticides | Enzyme inhibitors | Studies | Herbicides | Environmental science | Toxicity | Worms | Soil contamination | Index Medicus
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5. Full Text Priority and emerging flame retardants in rivers: Occurrence in water and sediment, Daphnia magna toxicity and risk assessment
by Cristale, Joyce and García Vázquez, Alejandro and Barata, Carlos and Lacorte, Silvia
Environment International, ISSN 0160-4120, 09/2013, Volume 59, pp. 232 - 243
The occurrence, partitioning and risk of eight polybrominated diphenyl ethers (PBDEs), nine new brominated (NBFRs) and ten organophosphorus flame retardants... 
D. magna toxicity | River | Organophosphate flame retardant | New brominated flame retardants | PBDE | Risk assessment | PHARMACEUTICALS | ENVIRONMENTAL OCCURRENCE | CHINA | MIXTURE TOXICITY | POLYBROMINATED DIPHENYL ETHERS | DECABROMODIPHENYL ETHANE | ENVIRONMENTAL SCIENCES | TREATMENT PLANTS | SURFACE WATERS | ORGANOPHOSPHATE ESTERS | PLASTICIZERS | Flame Retardants - analysis | Environmental Monitoring | Risk Assessment | Humans | Bromobenzenes - toxicity | Halogenated Diphenyl Ethers - analysis | Water Pollutants, Chemical - analysis | Bromobenzenes - analysis | Halogenated Diphenyl Ethers - toxicity | Daphnia - drug effects | Flame Retardants - toxicity | Animals | Water Pollutants, Chemical - toxicity | Rivers - chemistry | Geologic Sediments - chemistry | Biological Assay | Organophosphorus Compounds - analysis | Organophosphorus Compounds - toxicity | Water | Rivers | Fireproofing agents | Sediments (Geology) | Index Medicus | Partitioning | Toxicity | Flame retardants | Risk | Mathematical models | Ethers | Sediments
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6. Full Text The combined toxicity assessment of carp (Cyprinus carpio) acetylcholinesterase activity by binary mixtures of chlorpyrifos and four other insecticides
by Chen, Chen and Wang, Yanhua and Zhao, Xueping and Wang, Qiang and Qian, Yongzhong
Ecotoxicology, ISSN 0963-9292, 3/2014, Volume 23, Issue 2, pp. 221 - 228
Mixtures of organophosphate (OP) and carbamate (CB) insecticides are commonly detected in freshwater habitats. These insecticides inhibit the activity of... 
Environment, general | Ecotoxicology | Isobole | Concentration addition | Carbamates | Combined toxicity | Environment | Ecology | Cyprinus carpio | Environmental Management | Organophosphates | JOINT ALGAL TOXICITY | CHOLINESTERASE | ORGANOPHOSPHORUS | PESTICIDES | ENVIRONMENTAL SCIENCES | INHIBITION | DAPHNIA-MAGNA | ECOLOGY | TOXICOLOGY | ACTING CHEMICALS | RISK-ASSESSMENT | MULTIPLE CHEMICAL-MIXTURES | Pesticide Synergists - toxicity | Carps - metabolism | Animals | Cholinesterase Inhibitors - toxicity | Triazoles - toxicity | Organothiophosphates - toxicity | Chlorpyrifos - toxicity | Toxicity Tests - methods | Insecticides - toxicity | Malathion - toxicity | Acetylcholinesterase - metabolism | Carbamates - toxicity | Insecticides | Enzyme inhibitors | Animal behavior | Analysis | Index Medicus | Chlorpyrifos | Carp | Toxicity | Pesticides | Mathematical models | Inhibition | Binary mixtures
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7. Full Text Urban and agricultural sources of pyrethroid insecticides to the sacramento-san joaquin delta of California
by Weston, Donald P and Lydy, Michael J
Environmental Science and Technology, ISSN 0013-936X, 03/2010, Volume 44, Issue 5, pp. 1833 - 1840
While studies have documented the presence of pyrethroid insecticides at acutely toxic concentrations in sediments, little quantitative data on sources exist.... 
AQUATIC TOXICITY | ENVIRONMENTAL SCIENCES | ENGINEERING, ENVIRONMENTAL | FENVALERATE | ORGANOPHOSPHATE | SEDIMENT TOXICITY | RIVER | IDENTIFICATION EVALUATION TOOLS | RISK-ASSESSMENT | BIOAVAILABILITY | PESTICIDES | WATER | Pyrethrins - toxicity | Humans | Agriculture - methods | California | Rivers | Urban Population | Geologic Sediments | Rain | Animals | Water Pollutants, Chemical - toxicity | Pesticides - toxicity | Seasons | Insecticides - toxicity | Organophosphates - toxicity | Amphipoda - drug effects | Water treatment plants | Toxicity | Runoff | Pesticides | Insecticides | Agriculture | Sediments | Index Medicus
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8. Full Text Examining impacts of current‐use pesticides in Southern Ontario using in situ exposures of the amphipod Hyalella azteca
by Bartlett, Adrienne J and Struger, John and Grapentine, Lee C and Palace, Vince P
Environmental Toxicology and Chemistry, ISSN 0730-7268, 05/2016, Volume 35, Issue 5, pp. 1224 - 1238
In situ exposures with Hyalella azteca were used to assess impacts of current-use pesticides in Southern Ontario, Canada. Exposures were conducted over 2... 
Acetylcholinesterase inhibitors | Hyalella azteca | Organophosphate insecticides | Pesticides | In situ exposures | Diazinon - toxicity | Herbicides - toxicity | 2-Methyl-4-chlorophenoxyacetic Acid - analogs & derivatives | Amphipoda - enzymology | Animals | Atrazine - toxicity | Pesticides - toxicity | Acetamides - toxicity | Chlorpyrifos - toxicity | 2-Methyl-4-chlorophenoxyacetic Acid - toxicity | Seasons | 2,4-Dichlorophenoxyacetic Acid - toxicity | Insecticides - toxicity | Ontario | Acetylcholinesterase - metabolism | Amphipoda - drug effects | Azinphosmethyl - toxicity | Insecticides | Enzyme inhibitors | Analysis | Atrazine | Crustaceans | Water pollution | Toxicity | Aquatic ecosystems | Index Medicus
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9. Full Text Effects of endosulfan, thiamethoxam, and indoxacarb in combination with atrazine on multi-biomarkers in Gammarus kischineffensis
by Demirci, Özlem and Güven, Kemal and Asma, Dilek and Öğüt, Serdal and Uğurlu, Pelin
Ecotoxicology and Environmental Safety, ISSN 0147-6513, 01/2018, Volume 147, pp. 749 - 758
Studies addressing the toxicity of pesticides towards non-target organisms focus on the median lethal concentration and biochemical response of individual... 
Endosulfan | Thiamethoxam | Pesticide mixture | Indoxacarb | Gammarus kischineffensis | Atrazine | ANTIOXIDANT RESPONSES | INTEGRATED ASSESSMENT | ENVIRONMENTAL RISK-ASSESSMENT | ORGANOPHOSPHATE INSECTICIDES | GLUTATHIONE S-TRANSFERASES | JOINT TOXICITY | PESTICIDES | CARASSIUS-AURATUS | ENVIRONMENTAL SCIENCES | CHIRONOMUS-TENTANS | TOXICOLOGY | WATER | Nitro Compounds - toxicity | Biomarkers - analysis | Environmental Monitoring - methods | Neonicotinoids - toxicity | Herbicides - toxicity | Toxicity Tests, Acute | Lethal Dose 50 | Soil Pollutants - toxicity | Dose-Response Relationship, Drug | Drug Synergism | Oxazines - toxicity | Thiazoles - toxicity | Amphipoda - enzymology | Animals | Time Factors | Atrazine - toxicity | Endosulfan - toxicity | Oxidative Stress - drug effects | Insecticides - toxicity | Amphipoda - drug effects | Insecticides | Superoxide | Biological markers | Glutathione transferase | Analysis | Index Medicus
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10. Full Text Toxicity of new generation flame retardants to Daphnia magna
by Waaijers, Susanne L and Hartmann, Julia and Soeter, A. Marieke and Helmus, Rick and Kools, Stefan A.E and de Voogt, Pim and Admiraal, Wim and Parsons, John R and Kraak, Michiel H.S
Science of the Total Environment, ISSN 0048-9697, 10/2013, Volume 463-464, pp. 1042 - 1048
There is a tendency to substitute frequently used, but relatively hazardous brominated flame retardants (BFRs) with halogen-free flame retardants (HFFRs).... 
Halogen-free flame retardants | Toxicity | PBT properties | Brominated flame retardants | Daphnia magna | ENVIRONMENTAL SCIENCES | METALS | ACIDIFICATION | POLYBROMINATED DIPHENYL ETHERS | Daphnia - drug effects | Flame Retardants - toxicity | Animals | Water Pollutants, Chemical - toxicity | Antimony - toxicity | Benzhydryl Compounds - toxicity | Phenols - toxicity | Polybrominated Biphenyls - toxicity | Toxicity Tests, Acute - methods | Organophosphates - toxicity | Hydrogen-Ion Concentration | Phosphates | Bisphenol-A | Fireproofing agents | Antimony oxide | Index Medicus
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11. Full Text Reversal of Tabun Toxicity Enabled by a Triazole‐Annulated Oxime Library—Reactivators of Acetylcholinesterase
by Kovarik, Zrinka and Kalisiak, Jarosław and Hrvat, Nikolina Maček and Katalinić, Maja and Zorbaz, Tamara and Žunec, Suzana and Green, Carol and Radić, Zoran and Fokin, Valery V and Sharpless, K. Barry and Taylor, Palmer
Chemistry – A European Journal, ISSN 0947-6539, 03/2019, Volume 25, Issue 16, pp. 4100 - 4114
Acetylcholinesterase (AChE), an enzyme that degrades the neurotransmitter acetylcholine, when covalently inhibited by organophosphorus compounds (OPs), such as... 
acetylcholinesterase | nerve agents | organophosphate antidotes | heterocycles | biochemistry | PYRIDINIUM | CLICK CHEMISTRY | ORGANOPHOSPHATES | CRYSTAL-STRUCTURES | CHEMISTRY, MULTIDISCIPLINARY | OBIDOXIME | IN-VITRO EVALUATION | NERVE-AGENT | CHOLINESTERASES | Enzymes | Nerve gas | War use | Triazoles | Analysis | Gases, Asphyxiating and poisonous | Nitriles | Acetylcholine | Oximes | Tabun | Antidotes | Toxicity | Pesticides | Prophylaxis | Pyridinium | Activation | Exposure | Acetylcholinesterase | Biocompatibility | Organophosphorus compounds | Inhibition | Nerve agents | Alkynes | Biological & chemical weapons
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12. Full Text Diphenyl Phosphate-Induced Toxicity during Embryonic Development
by Mitchell, Constance A and Reddam, Aalekhya and Dasgupta, Subham and Zhang, Sharon and Stapleton, Heather M and Volz, David C
Environmental Science and Technology, ISSN 0013-936X, 2019, Volume 53, Issue 7, pp. 3908 - 3916
Diphenyl phosphate (DPHP) is an aryl phosphate ester (APE) used as an industrial catalyst and chemical additive and is the primary metabolite of flame... 
ZEBRAFISH EMBRYOGENESIS | ENVIRONMENTAL SCIENCES | ASSOCIATIONS | DISRUPTION | METABOLISM | ENGINEERING, ENVIRONMENTAL | TRIPHENYL PHOSPHATE | ORGANOPHOSPHATE FLAME RETARDANTS | CARDIOTOXICITY | POTENTIAL ROLE | EXPRESSION | EXPOSURE | Heart | Phosphates | Toxicity | Flame retardants | mRNA | Biosynthesis | Gene sequencing | Human populations | Embryogenesis | Mitochondria | Aromatic compounds | Mannitol | Heme | Hemoglobin | Phosphate esters | Pretreatment | Edema | Apes | Fire retardant chemicals | Fire retardants | Zebrafish | Exposure | Metabolism | Embryonic growth stage | Organic chemistry
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13. Full Text Role of oxidative stress in organophosphate insecticide toxicity – Short review
by Lukaszewicz-Hussain, Anna
Pesticide Biochemistry and Physiology, ISSN 0048-3575, 2010, Volume 98, Issue 2, pp. 145 - 150
The objective of this paper is to present a short review of the state of knowledge regarding oxidative stress and its role in toxicity of organophosphate... 
Organophosphate | Oxidative stress | Toxicity | EXPERIMENTAL RATS | PHYSIOLOGY | LIPID-PEROXIDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | LANGERHANS ISLETS | ANTIOXIDANT ENZYMES | N-ACETYLCYSTEINE | ENTOMOLOGY | FREE-RADICALS | ACETYLCHOLINESTERASE INHIBITION | CHOLINESTERASE ACTIVITY | INTERMEDIATE SYNDROME | PARKINSONS-DISEASE | Antioxidants | Insecticides | Hyperglycemia | Poisoning | Analysis
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