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The New England Journal of Medicine, ISSN 0028-4793, 02/2015, Volume 372, Issue 6, pp. 509 - 518
Preventing HIV-1 infection is a high global priority. This study assessed prevention strategies in young women in South Africa, Uganda, and Zimbabwe using oral... 
TRIALS | MEDICINE, GENERAL & INTERNAL | TRANSMISSION | ANTIRETROVIRAL PROPHYLAXIS | MICROBICIDE | PREVENTION | ADHERENCE | GEL | HIV Infections - prevention & control | Humans | Middle Aged | Drug Resistance, Viral | Administration, Intravaginal | Deoxycytidine - blood | Adenine - blood | Tenofovir | Young Adult | Adenine - adverse effects | Adult | Deoxycytidine - adverse effects | Female | Organophosphonates - blood | Surveys and Questionnaires | Anti-Retroviral Agents - blood | Drug Therapy, Combination | Emtricitabine | Adenine - analogs & derivatives | HIV Seropositivity | Administration, Oral | HIV-1 - drug effects | Deoxycytidine - administration & dosage | Anti-Retroviral Agents - adverse effects | Organophosphonates - adverse effects | Africa South of the Sahara | Adenine - administration & dosage | Pre-Exposure Prophylaxis | Organophosphonates - administration & dosage | Medication Adherence | Anti-Retroviral Agents - administration & dosage | Adolescent | HIV Infections - complications | Deoxycytidine - analogs & derivatives | Women | Care and treatment | HIV infection in women | Dosage and administration | HIV infection | Health aspects | Risk factors | Intervention | Creatinine | Antiretroviral drugs | Motivation | Human immunodeficiency virus--HIV | Prophylaxis | Vagina | Infections | Preventive medicine
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2010, Volume 363, Issue 27, pp. 2587 - 2599
In this study, 2499 HIV-seronegative men or transgender women who were at high risk for HIV acquisition were enrolled in a trial of daily emtricitabine plus... 
TRIAL | MEDICINE, GENERAL & INTERNAL | NONOCCUPATIONAL POSTEXPOSURE PROPHYLAXIS | LIMITED KNOWLEDGE | TRANSMISSION | HOMOSEXUAL-MEN | MALE CIRCUMCISION | RISK | INFECTION | MACAQUES | TENOFOVIR | HIV Antibodies - blood | HIV Infections - prevention & control | Follow-Up Studies | Nausea - chemically induced | HIV Infections - epidemiology | Humans | Middle Aged | Drug Resistance, Viral | Male | RNA, Viral - blood | Deoxycytidine - blood | Incidence | Adenine - blood | Tenofovir | Young Adult | Deoxycytidine - therapeutic use | Adenine - adverse effects | Homosexuality, Male | Adenine - therapeutic use | HIV Infections - diagnosis | Adult | Anti-HIV Agents - therapeutic use | Deoxycytidine - adverse effects | Organophosphonates - blood | Anti-HIV Agents - blood | Drug Therapy, Combination | Emtricitabine | Adenine - analogs & derivatives | Transsexualism | Organophosphonates - therapeutic use | Administration, Oral | Anti-HIV Agents - adverse effects | Kaplan-Meier Estimate | Organophosphonates - adverse effects | HIV - isolation & purification | HIV Seropositivity - diagnosis | Adolescent | HIV - genetics | Patient Compliance | Deoxycytidine - analogs & derivatives | Usage | Transgender people | Diagnosis | Drug therapy | Health aspects | HIV infection | Mens health | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Alcohol use
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. e55013
Background: Oral and vaginal preparations of tenofovir as pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) infection have demonstrated... 
NUCLEOSIDE | LAMIVUDINE | CELLS | ACTIVATION | PREEXPOSURE | METABOLISM | DIPHOSPHATE | MULTIDISCIPLINARY SCIENCES | DISOPROXIL FUMARATE | DILUTION ASSESSMENT | IMMUNODEFICIENCY-VIRUS ACTIVITY | Anti-HIV Agents - pharmacology | HIV Infections - prevention & control | Phosphorylation | Tablets | Vagina - drug effects | Humans | Middle Aged | Phosphorous Acids - administration & dosage | Anti-HIV Agents - administration & dosage | Phosphorous Acids - adverse effects | Tenofovir | Young Adult | Adenine - adverse effects | Phosphorous Acids - pharmacokinetics | Adult | Female | Vaginal Creams, Foams, and Jellies | Vagina - cytology | Adenine - analogs & derivatives | Administration, Oral | Anti-HIV Agents - adverse effects | Rectum - metabolism | Organophosphonates - adverse effects | Adenine - pharmacology | Adenine - pharmacokinetics | Adenine - administration & dosage | Organophosphonates - pharmacokinetics | Cross-Over Studies | Organophosphonates - administration & dosage | Organophosphonates - pharmacology | Phosphorous Acids - pharmacology | Anti-HIV Agents - pharmacokinetics | Adolescent | Vagina - virology | Vagina - metabolism | Infection | Clinical trials | HIV (Viruses) | Health aspects | Laboratories | Prophylaxis | Viruses | Infections | Drug development | Mens health | Randomization | Acquired immune deficiency syndrome--AIDS | Compartments | Human immunodeficiency virus--HIV | Drug dosages | Public health | Dosing | Antiretroviral drugs | Effectiveness | Vagina | Pharmacology | Metabolism | Medicine | Studies | Womens health | Collaboration | Rectum | Pharmacokinetics | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article
Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5996, pp. 1168 - 1174
The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed the effectiveness and safety of a 1% vaginal gel formulation of... 
Human sexual behavior | HIV infections | Antiinfectives | Gels | HIV | RESEARCH ARTICLES | Placebos | Experimentation | AIDS | Infections | Condoms | VAGINAL GEL | INDIVIDUALS | SOUTH-AFRICA | PROPHYLAXIS | IN-VITRO | TRANSMISSION | MULTIDISCIPLINARY SCIENCES | CLINICAL-TRIALS | MALE CIRCUMCISION | RANDOMIZED CONTROLLED-TRIAL | CHALLENGES | HIV Infections - prevention & control | Anti-Infective Agents, Local - therapeutic use | Urban Population - statistics & numerical data | HIV Infections - epidemiology | Humans | Anti-Infective Agents, Local - adverse effects | Drug Resistance, Viral | Administration, Intravaginal | Viral Load | Incidence | Anti-HIV Agents - administration & dosage | Tenofovir | Young Adult | Adenine - adverse effects | HIV-1 - physiology | Adenine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Female | Vaginal Creams, Foams, and Jellies | Rural Population - statistics & numerical data | Sexual Behavior | Adenine - analogs & derivatives | Double-Blind Method | Organophosphonates - therapeutic use | HIV-1 - drug effects | Anti-HIV Agents - adverse effects | South Africa - epidemiology | Organophosphonates - adverse effects | Adenine - administration & dosage | Pregnancy | Organophosphonates - administration & dosage | Anti-Infective Agents, Local - administration & dosage | Adolescent | Patient Compliance | Pregnancy Outcome | Prevention | Anti-infective agents | Research | HIV infection
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2008, Volume 359, Issue 23, pp. 2442 - 2455
Journal Article