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1983, 1, ISBN 0849357241, Volume 1, 207
Throughout the last three decades, a large amount of information on phosphonates has accumulated, but has not been compiled. At this time of the increasing... 
Acides phosphoniques | Phosphonic acids | Phosphonates | Effets physiologiques | Metabolism | Physiological effect | Métabolisme | Complementary & Alternative Medicine | Phosphonic acids-Metabolism | Phosphonic acids-Physiological effect | Phosphonates-Physiological effect | Phosphonates-Metabolism
Book
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 11/2017, Volume 114, Issue 47, pp. E10083 - E10091
EmrE is a small multidrug resistance transporter found in that confers resistance to toxic polyaromatic cations due to its proton-coupled antiport of these... 
Membrane protein | NMR | Coupled transport | Protein dynamics | Multidrug transport | MULTIDRUG TRANSPORTER | MULTIDISCIPLINARY SCIENCES | protein dynamics | ESCHERICHIA-COLI | ACTIVE-TRANSPORT | coupled transport | P-GLYCOPROTEIN | STATE ANALYSIS | CONFORMATIONAL-CHANGES | SUBSTRATE-BINDING | PROTON RELEASE | multidrug transport | DYNAMICS | membrane protein | RESIDUE | Protons | Antiporters - chemistry | Escherichia coli - drug effects | Proteolipids - metabolism | Substrate Specificity | Onium Compounds - metabolism | Phosphatidylcholines - metabolism | Organophosphorus Compounds - metabolism | Xenobiotics - chemistry | Xenobiotics - pharmacology | Thermodynamics | Biological Transport | Antiporters - genetics | Dicyclohexylcarbodiimide - toxicity | Escherichia coli - metabolism | Organophosphorus Compounds - pharmacology | Protein Interaction Domains and Motifs | Xenobiotics - metabolism | Binding Sites | Onium Compounds - chemistry | Phosphatidylglycerols - metabolism | Recombinant Proteins - metabolism | Gene Expression | Protein Structure, Secondary | Recombinant Proteins - chemistry | Antiporters - metabolism | Escherichia coli Proteins - metabolism | Organophosphorus Compounds - chemistry | Recombinant Proteins - genetics | Onium Compounds - pharmacology | Phosphatidylcholines - chemistry | Molecular Dynamics Simulation | Phosphatidylglycerols - chemistry | Escherichia coli - genetics | Escherichia coli Proteins - genetics | Protein Binding | Kinetics | Drug Resistance, Multiple, Bacterial - genetics | Escherichia coli Proteins - chemistry | Hydrogen-Ion Concentration | Proteolipids - chemistry | Physiological aspects | Carrier proteins | Observations | Protein-protein interactions | Biological Sciences | PNAS Plus
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 330, Issue 6000, pp. 70 - 74
Taxol (paclitaxel) is a potent anticancer drug first isolated from the Taxus brevifolia Pacific yew tree. Currently, cost-efficient production of Taxol and its... 
Enzymes | Cellular metabolism | Terpenoids | Chemical engineering | Bioreactors | Plasmids | REPORTS | Operons | Biosynthesis | Indoles | Streams | YEAST | CYTOCHROME-P450 | TAXADIENE | CELLS | MULTIDISCIPLINARY SCIENCES | CONSTRUCTION | BIOSYNTHETIC GENES | STEP | OXYGENASES | LYCOPENE PRODUCTION | TERPENOIDS | Metabolomics | NADPH-Ferrihemoprotein Reductase - genetics | Erythritol - analogs & derivatives | Cytochrome P-450 Enzyme System - metabolism | Taxoids - metabolism | Organophosphorus Compounds - metabolism | Recombinant Fusion Proteins - metabolism | Farnesyltranstransferase - metabolism | Escherichia coli K12 - metabolism | Hemiterpenes - metabolism | Indoles - metabolism | Terpenes - metabolism | Erythritol - metabolism | Isomerases - genetics | Diterpenes - metabolism | NADPH-Ferrihemoprotein Reductase - metabolism | Paclitaxel - biosynthesis | Oxidation-Reduction | Fermentation | Taxus - enzymology | Metabolic Networks and Pathways - genetics | Genetic Engineering | Sugar Phosphates - metabolism | Farnesyltranstransferase - genetics | Cytochrome P-450 Enzyme System - genetics | Isomerases - metabolism | Escherichia coli K12 - genetics | Alkenes - metabolism | Escherichia coli K12 - enzymology | Physiological aspects | Research | Health aspects | Escherichia coli | Biological transport | Biochemistry | Pharmacology | E coli
Journal Article
Biochemical journal, ISSN 1470-8728, 2006, Volume 400, Issue 1, pp. 199 - 208
Lipophilic monocations can pass through phospholipid bilayers and accumulate in negatively-charged compartments such as the mitochondrial matrix, driven by the... 
Mitochondria | Mitochondrial targeting | Lipophilic cations | Membrane potential | Membrane transport | Dications | OXIDATIVE STRESS | 1-METHYL-4-PHENYLPYRIDINIUM | dications | PHOSPHORYLATION | mitochondria | BIOMEMBRANE-PRODUCED ENERGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCTION | PLASMA-MEMBRANE | BIOENERGETICS | ANTIOXIDANT | lipophilic cations | membrane potential | membrane transport | ELECTRIC FORM | PROTEINS | mitochondrial targeting | Uncoupling Agents - pharmacology | Intracellular Membranes - physiology | Mitochondria, Liver - metabolism | Humans | Onium Compounds - metabolism | Organophosphorus Compounds - metabolism | Trityl Compounds - chemistry | Mitochondria, Liver - physiology | Rubidium Radioisotopes - metabolism | Lipids - chemistry | Tritium - metabolism | Adenosine Triphosphate - metabolism | Cations, Divalent - metabolism | Potassium Chloride - pharmacology | Rotenone - pharmacology | Biological Transport - drug effects | Onium Compounds - chemistry | Ionophores - pharmacology | Cations, Divalent - chemistry | Membrane Potentials - drug effects | Jurkat Cells | Rats | Organophosphorus Compounds - chemistry | Mitochondria - metabolism | Mitochondria - drug effects | Membrane Potentials - physiology | Mitochondria, Liver - drug effects | Terphenyl Compounds - metabolism | Terphenyl Compounds - chemistry | Algorithms | Animals | Biological Transport - physiology | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone - pharmacology | Intracellular Membranes - drug effects | Nigericin - pharmacology | Lipid Bilayers - metabolism | Mitochondria - physiology | Intracellular Membranes - metabolism | Trityl Compounds - metabolism | TPB, tetraphenyl borate anion | ACR, accumulation ratio | ΔΨ, mitochondrial membrane potential | FCS, foetal calf serum | BLM, bilayer planar phospholipid membrane | FCCP, carbonylcyanide-p-trifluoromethoxyphenylhydrazone | PCnP, bistriphenylphosphonium cation linked by an n carbon methylene bridge | TPP, triphenylphosphonium cation | TPMP, methyltriphenylphosphonium cation
Journal Article
Journal of inorganic biochemistry, ISSN 0162-0134, 2019, Volume 198, p. 110750
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 10/2013, Volume 110, Issue 43, pp. 17273 - 17277
Journal Article
Archives of toxicology, ISSN 1432-0738, 2015, Volume 90, Issue 11, pp. 2711 - 2724
... with structurally different organophosphorus compounds in vitro Moshe Goldsmith 2 · Simone Eckstein 1 · Yacov Ashani 2 · Per Greisen Jr. 3 · Haim Leader 4 · Joel L. Sussman 5... 
Biomedicine, general | Bioscavenger | Biomedicine | Environmental Health | Phosphotriesterase | Occupational Medicine/Industrial Medicine | Organophosphate hydrolase | Mutant | Detoxification | Organophosphorus compounds | Pharmacology/Toxicology | HYDROLASES | PROTECTION | RESOLUTION | TOXICITY | ZINC | NERVE AGENTS | EVOLUTION | TOXICOLOGY | Inactivation, Metabolic | Stereoisomerism | Escherichia coli - drug effects | Substrate Specificity | Peptide Library | Organophosphorus Compounds - metabolism | Recombinant Fusion Proteins - metabolism | Pseudomonas - enzymology | Escherichia coli - metabolism | Protein Engineering | Clone Cells | Molecular Structure | Escherichia coli - growth & development | Pesticides - metabolism | Nerve Agents - chemistry | Biocatalysis | Nerve Agents - metabolism | Phosphoric Triester Hydrolases - genetics | Bacterial Proteins - genetics | Computational Biology | Organophosphorus Compounds - chemistry | Directed Molecular Evolution | Nerve Agents - toxicity | High-Throughput Screening Assays | Pesticides - toxicity | Pesticides - chemistry | Bacterial Proteins - metabolism | Phosphoric Triester Hydrolases - metabolism | Molecular Docking Simulation | Mutation | Amino Acid Substitution | Enzymes | Nerve gas | War use | Enantiomers | Gases, Asphyxiating and poisonous | Pesticides
Journal Article