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Journal of Clinical Oncology, ISSN 0732-183X, 08/2017, Volume 35, Issue 22, pp. 2490 - 2498
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2018, Volume 379, Issue 21, pp. 2027 - 2039
In a randomized trial involving patients with ALK -rearranged lung cancer, brigatinib was associated with longer progression-free survival and more activity... 
MEDICINE, GENERAL & INTERNAL | CERITINIB | EML4-ALK FUSION GENE | RESISTANCE | OPEN-LABEL | KINASE INHIBITOR | SINGLE-ARM | EGFR | CHEMOTHERAPY | Lung Neoplasms - drug therapy | Carcinoma, Non-Small-Cell Lung - chemistry | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Antineoplastic Agents - therapeutic use | Brain Neoplasms - secondary | Carcinoma, Non-Small-Cell Lung - secondary | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Organophosphorus Compounds - adverse effects | Crizotinib - therapeutic use | Lung Neoplasms - chemistry | Anaplastic Lymphoma Kinase - analysis | Kaplan-Meier Estimate | Organophosphorus Compounds - therapeutic use | Crizotinib - adverse effects | Pyrimidines - therapeutic use | Progression-Free Survival | Pyrimidines - adverse effects | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Anaplastic Lymphoma Kinase - antagonists & inhibitors | Crizotinib | Cancer patients | Safety and security measures | Development and progression | Dosage and administration | Comparative analysis | Lung cancer, Non-small cell | Drug therapy | Health aspects | Nuclear magnetic resonance--NMR | Medical imaging | Statistical analysis | Lung cancer | Metastasis | Radiation therapy | Lymphoma | Cancer therapies | Chemotherapy | Technical communication | Mutation | Protein-tyrosine kinase | Drug dosages | Pharmaceuticals | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 09/2012, Volume 53, Issue 5, pp. 1123 - 1138
Mitochondrial reactive oxygen species generation has been implicated in the pathophysiology of ischemia–reperfusion (I/R) injury; however, its exact role and... 
Antioxidants | Oxidative stress | Free radicals | Ischemia–reperfusion | Reactive oxygen and nitrogen species | APOPTOSIS | ISCHEMIA/REPERFUSION INJURY | SUPEROXIDE | PEROXYNITRITE | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIVER ISCHEMIA | HMGB1 RELEASE | CELL-DEATH | Ischemia-reperfusion | IN-VIVO | ENDOCRINOLOGY & METABOLISM | NITRIC-OXIDE | Reactive Oxygen Species - metabolism | Mitochondria, Liver - metabolism | Reperfusion Injury - drug therapy | Male | Ubiquinone - pharmacology | Dose-Response Relationship, Drug | Cyclic N-Oxides - therapeutic use | Inflammation - metabolism | Cyclic N-Oxides - pharmacology | Inflammation - drug therapy | Organophosphorus Compounds - pharmacology | Ubiquinone - therapeutic use | Reperfusion Injury - metabolism | Mice, Inbred C57BL | Ubiquinone - analogs & derivatives | Organophosphorus Compounds - therapeutic use | Antioxidants - pharmacology | Mitochondria, Liver - drug effects | Antioxidants - therapeutic use | Animals | Reperfusion Injury - physiopathology | Liver Diseases - drug therapy | Mice | Liver Diseases - physiopathology | Oxidative Stress - drug effects | Liver Diseases - metabolism | Medical colleges | Liver diseases | Analysis | Alcoholism | Inflammation | Mitochondrial DNA | Health aspects | Free radicals (Chemistry) | Cells | Index Medicus | ischemia-reperfusion | antioxidants | reactive oxygen and nitrogen species | oxidative stress
Journal Article