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1. Full Text Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease
by Weekley, Claire M and Harris, Hugh H
Chemical Society reviews, ISSN 0306-0012, 11/2013, Volume 42, Issue 23, pp. 887 - 8894
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Selenocysteine - metabolism | Selenomethionine - metabolism | Reactive Oxygen Species - metabolism | Humans | Neoplasms - prevention & control | Selenium Compounds - metabolism | Clinical Trials as Topic | Histone Deacetylase Inhibitors - chemistry | Selenoproteins - metabolism | Selenomethionine - therapeutic use | Selenoproteins - chemistry | Cystine - metabolism | Cystine - therapeutic use | Sulfhydryl Compounds - chemistry | Selenocysteine - therapeutic use | Histone Deacetylase Inhibitors - metabolism | Selenocysteine - analogs & derivatives | Cystine - analogs & derivatives | Dietary Supplements | Selenium Compounds - therapeutic use | Organoselenium Compounds - metabolism | Organoselenium Compounds - therapeutic use | Index Medicus | Selenium compounds | Pathways | Medical services | Selenium | Biological | Metabolism | Chemical compounds | Speciation
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2. Full Text Synthesis and Evaluation of Multi-Target-Directed Ligands against Alzheimer’s Disease Based on the Fusion of Donepezil and Ebselen
by Luo, Zonghua and Sheng, Jianfei and Sun, Yang and Lu, Chuanjun and Yan, Jun and Liu, Anqiu and Luo, Hai-bin and Huang, Ling and Li, Xingshu
Journal of medicinal chemistry, ISSN 0022-2623, 11/2013, Volume 56, Issue 22, pp. 9089 - 9099
Cholinesterase Inhibitors - toxicity | Organoselenium Compounds - chemical synthesis | Humans | Azoles - metabolism | Cholinesterase Inhibitors - chemical synthesis | Toxicity Tests, Acute | Molecular Targeted Therapy | Organoselenium Compounds - pharmacology | Cholinesterase Inhibitors - metabolism | Piperidines - pharmacology | Thioredoxin-Disulfide Reductase - metabolism | Butyrylcholinesterase - metabolism | Azoles - toxicity | Glutathione Peroxidase - metabolism | Piperidines - toxicity | Chemistry Techniques, Synthetic | Protein Structure, Secondary | Piperidines - metabolism | Indans - metabolism | Alzheimer Disease - drug therapy | Electrophorus | Acetylcholinesterase - chemistry | Azoles - chemical synthesis | Azoles - pharmacology | Piperidines - chemical synthesis | Organoselenium Compounds - toxicity | Peptide Fragments - chemistry | Animals | Cholinesterase Inhibitors - pharmacology | Peroxynitrous Acid - metabolism | Indans - toxicity | Indans - chemical synthesis | Ligands | Mice | Molecular Docking Simulation | Amyloid beta-Peptides - chemistry | Kinetics | Acetylcholinesterase - metabolism | Organoselenium Compounds - metabolism | Protein Multimerization - drug effects | Indans - pharmacology | Index Medicus
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3. Full Text 4-Phenylselenyl-7-chloroquinoline, a new quinoline derivative containing selenium, has potential antinociceptive and anti-inflammatory actions
by Pinz, Mikaela and Reis, Angélica S and Duarte, Vanessa and da Rocha, Márcia J and Goldani, Bruna S and Alves, Diego and Savegnago, Lucielli and Luchese, Cristiane and Wilhelm, Ethel A
European journal of pharmacology, ISSN 0014-2999, 06/2016, Volume 780, pp. 122 - 128
Nociception | Quinoline | Myeloperoxidase | Inflammation | Mice | Selenium | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Analgesics - pharmacology | Analgesics - metabolism | Male | Anti-Inflammatory Agents - metabolism | Biphenyl Compounds - metabolism | Organoselenium Compounds - pharmacology | Quinolines - pharmacology | Anti-Inflammatory Agents - therapeutic use | Behavior, Animal - drug effects | Quinolines - toxicity | Benzothiazoles - metabolism | Organoselenium Compounds - therapeutic use | Analgesics - therapeutic use | Anti-Inflammatory Agents - pharmacology | Anti-Inflammatory Agents - toxicity | Picrates - metabolism | Edema - drug therapy | Analgesics - toxicity | Organoselenium Compounds - toxicity | Sulfonic Acids - metabolism | Quinolines - metabolism | Animals | Quinolines - therapeutic use | Organoselenium Compounds - metabolism | Peroxidase - metabolism | Meloxicam | Antioxidants | Acetic acid | Organic acids | Formaldehyde | Alkaloids | Anti-inflammatory drugs | Index Medicus
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4. Full Text Selenium compounds as therapeutic agents in cancer
by Fernandes, Aristi P and Gandin, Valentina
Biochimica et biophysica acta. General subjects, ISSN 0304-4165, 08/2015, Volume 1850, Issue 8, pp. 1642 - 1660
Cell death | Chemotherapeutics | Selenium | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Neoplasms - metabolism | Nanoparticles - chemistry | Apoptosis - drug effects | Humans | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - chemistry | Organoselenium Compounds - chemistry | Neoplasms - drug therapy | Oxidation-Reduction - drug effects | Selenium Compounds - chemistry | Molecular Structure | Nanoparticles - administration & dosage | Oxidative Stress - drug effects | Selenium Compounds - therapeutic use | Organoselenium Compounds - therapeutic use | Selenium compounds | Antioxidants | Chemotherapy | Health aspects | Cancer
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5. Full Text Antidepressant-like effect of a new selenium-containing compound is accompanied by a reduction of neuroinflammation and oxidative stress in lipopolysaccharide-challenged mice
by Casaril, Angela M and Domingues, Micaela and Fronza, Mariana and Vieira, Beatriz and Begnini, Karine and Lenardão, Eder J and Seixas, Fabiana K and Collares, Tiago and Nogueira, Cristina W and Savegnago, Lucielli
Journal of psychopharmacology (Oxford), ISSN 0269-8811, 9/2017, Volume 31, Issue 9, pp. 1263 - 1273
toxicity | depression | Organoselenium | neuroinflammation | oxidative stress | Neurosciences | Clinical Neurology | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Neurosciences & Neurology | Psychiatry | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Selenium - pharmacology | Interleukin-4 - metabolism | Depressive Disorder - drug therapy | Male | Hippocampus - drug effects | Depressive Disorder - metabolism | Depression - drug therapy | Hippocampus - metabolism | Depression - metabolism | Inflammation - metabolism | Animals | Prefrontal Cortex - drug effects | Inflammation - drug therapy | Interleukin-1beta - metabolism | Lipopolysaccharides - pharmacology | Prefrontal Cortex - metabolism | Behavior, Animal - drug effects | Antidepressive Agents - pharmacology | Brain-Derived Neurotrophic Factor - metabolism | Mice | Swimming | Oxidative Stress - drug effects | Interleukin-6 - metabolism | Oxidative stress | Analysis | Selenium | Selenium compounds | Brain | Mental disorders | Syngeneic grafts | Liver | Indole | Organoselenium compounds | Interleukin | Mental depression | Dehydration | Lipopolysaccharides | Interleukin 6 | Interleukin 4 | Antidepressants | Rodents | Indoles | Pretreatment | Creatinine | Alanine | Kidneys | Pharmacology | Inflammation | Prefrontal cortex | Chemical compounds | Alanine transaminase | Biomarkers | Aspartate aminotransferase | Index Medicus
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