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PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e38386
Statins are widely prescribed for reducing LDL-cholesterol (C) and risk for cardiovascular disease (CVD), but there is considerable variation in therapeutic... 
KIDNEY-DISEASE | ALLOPURINOL | XANTHINE-OXIDASE | THERAPY | CHOLESTEROL | METABOLISM | MULTIDISCIPLINARY SCIENCES | PHARMACOGENOMICS | EXPRESSION | STATINS | GLOBAL BIOCHEMICAL APPROACH | Metabolomics | Simvastatin - therapeutic use | Gas Chromatography-Mass Spectrometry | Ornithine - blood | Xanthine - blood | Humans | alpha-Tocopherol - blood | Male | Simvastatin - pharmacology | Biomarkers, Pharmacological - blood | Succinic Acid - blood | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Stearic Acids - blood | Cystine - blood | Adult | Amino Acids, Essential - blood | Cholesterol, LDL - blood | Female | Fructose - blood | Nitric Oxide Synthase - blood | Citrulline - blood | Lauric Acids - blood | Pharmacogenetics | Low density lipoproteins | Simvastatin | Amino acids | Fructose | Cardiovascular agents | Antilipemic agents | Purines | Urea | Metabolites | Blood cholesterol | Nitric oxide | Analysis | Tocopherols | Cardiovascular diseases | Health aspects | Saturated fatty acids | Drugs | Lipoproteins (low density) | Lauric acid | Heart surgery | Genomics | Metadata | Cardiovascular disease | Cystine | Spectrometry | Microbiota | Ischemia | Arginine | Hydroxyvaleric acid | Stearic acid | Lipid metabolism | Bioinformatics | Statins | Discriminant analysis | Health risks | Pharmacology | Exposure | Citrulline | Xanthine | Metabolism | Cholesterol | Nitric-oxide synthase | Substrates | Intermediates | Studies | Gas chromatography | Lysine | Succinic acid | Biomarkers | Gastrointestinal surgery | Diabetes | Tocopherol | Ornithine
Journal Article
Brain Research, ISSN 0006-8993, 10/2016, Volume 1648, Issue Pt A, pp. 232 - 242
The blood–brain barrier (BBB) is a biological firewall that carefully regulates the cerebral microenvironment by acting as a physical, metabolic and transport... 
Guanosine triphosphatases (GTPases) | Cationic amino acid transporter 1 | Nitric oxide | Cerebral microvasculature | LEG SKELETAL-MUSCLE | OXIDATIVE STRESS | NITRIC-OXIDE SYNTHASE | ALZHEIMERS-DISEASE | CEREBROSPINAL-FLUID | NEUROSCIENCES | ENDOTHELIAL-CELL LINE | FREE AMINO-ACIDS | ISCHEMIC-STROKE | DRUG TRANSPORT | JUNCTION PROTEINS | Cell Line | Cell Survival - drug effects | Reactive Oxygen Species - metabolism | Humans | Enzyme Inhibitors - pharmacology | Ornithine - pharmacology | Ornithine - analogs & derivatives | Cationic Amino Acid Transporter 1 - metabolism | Permeability | Arginine - analogs & derivatives | Blood-Brain Barrier - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Arginine - pharmacology | Sucrose - metabolism | In Vitro Techniques | Nitric Oxide - metabolism | Arginine - metabolism | Interferon-gamma - pharmacology | Dextran | Arginine | Analysis | Endothelium | Interferon | G proteins | Index Medicus | CAT-1, cationic amino acid transporter 1 | TNF-α, tumour necrosis factor alpha | OCT, organic cation transporter | GTPases, guanosine triphosphatases | NOS, nitric oxide synthase | OSPC, octanol-saline partition coefficient | LAT, large neutral amino acid transporters | BBB, blood-brain barrier | CAA, cationic amino acids | IFN-γ, interferon gamma | DDAH, NG, NG-dimethylarginine dimethylaminohydrolase | MATE1, multidrug and toxin exclusion protein 1 | PRMTs, protein-arginine methyltransferases | ADMA, asymmetric dimethylarginine | NO, nitric oxide | Research Report | L-NIO, N-iminoethyl-L-ornithine | ROS, reactive oxygen species
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, p. e0125206
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e66823
Diabetes mellitus (DM) is a worldwide disease characterized by metabolic disturbances, frequently associated with high risk of atherosclerosis and renal and... 
OXIDATIVE STRESS | LIPID-PEROXIDATION | AMINO-ACID-TRANSPORT | SHEEP ERYTHROCYTES | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | RELAXING FACTOR | NITRIC-OXIDE | SICKLE-CELL-DISEASE | ARGINASE ACTIVITY | BLOOD-CELLS | Ornithine - blood | Oxidative Stress | Humans | Middle Aged | Carbon Isotopes | Hyperglycemia - complications | Male | Diabetes Mellitus, Type 2 - metabolism | Urea - blood | Case-Control Studies | Malondialdehyde - blood | Hyperglycemia - pathology | Nitrites - blood | Adult | Female | Citrulline - blood | Diabetes Mellitus, Type 2 - complications | Hemolysis | Endothelial Cells - metabolism | Hemoglobins - metabolism | Glycosylation | Hyperglycemia - metabolism | Diabetes Mellitus, Type 2 - blood | Hyperglycemia - blood | Metabolic Networks and Pathways | Models, Biological | Erythrocytes - metabolism | Aged | Diabetes Mellitus, Type 2 - pathology | Blood Glucose - metabolism | Nitric Oxide - metabolism | Arginine - metabolism | Type 2 diabetes | Urea | Hyperglycemia | Arginine | Metabolites | Blood sugar | Nitric oxide | Atherosclerosis | Physiological aspects | Diabetes therapy | Oxidative stress | Pathogenesis | Nitrites | Erythrocytes | Amino acids | Nervous system | Arginase | Polyamines | Blood | Red blood cells | Nitrogen metabolism | Rodents | Redox properties | Sickle cell disease | Hypertension | Damage assessment | Kidneys | Diabetes mellitus | Blood cells | Byproducts | Citrulline | Metabolism | Patients | Nitric-oxide synthase | Malondialdehyde | Endothelium | Serum levels | Hepatocytes | Arteriosclerosis | Catabolism | Diabetes | Ornithine | Kidney transplantation
Journal Article
European Journal of Applied Physiology, ISSN 1439-6319, 9/2010, Volume 110, Issue 2, pp. 341 - 351
Journal Article
Brain, Behavior, and Immunity, ISSN 0889-1591, 2015, Volume 52, Issue oct 26, pp. 153 - 160
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2009, Volume 29, Issue 9, pp. 1383 - 1391
Journal Article