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International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2012, Volume 82, Issue 1, pp. 291 - 298
Purpose To update the Memorial Sloan-Kettering Cancer Center’s experience with intensity-modulated radiotherapy (IMRT) in the treatment of oropharyngeal cancer... 
Radiology | Hematology, Oncology and Palliative Medicine | Head-and-neck cancer | Dysphagia | IMRT | Xerostomia | Oropharyngeal cancer | HEAD | SPARING RADIOTHERAPY | NECK-CANCER | RADIATION-THERAPY | SALIVARY-GLAND FUNCTION | IMPACT | ONCOLOGY | SQUAMOUS-CELL CARCINOMA | QUALITY-OF-LIFE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Pharyngeal Neoplasms - radiotherapy | Follow-Up Studies | Humans | Middle Aged | Oropharyngeal Neoplasms - mortality | Palate, Soft | Male | Oropharyngeal Neoplasms - pathology | Pharyngeal Neoplasms - drug therapy | Tongue Neoplasms - drug therapy | Incidence | New York City | Palatal Neoplasms - mortality | Treatment Failure | Aged, 80 and over | Adult | Female | Xerostomia - epidemiology | Tongue Neoplasms - radiotherapy | Radiotherapy Dosage | Tongue Neoplasms - mortality | Tonsillar Neoplasms - pathology | Oropharyngeal Neoplasms - drug therapy | Palatal Neoplasms - radiotherapy | Deglutition Disorders - epidemiology | Palatal Neoplasms - pathology | Oropharyngeal Neoplasms - radiotherapy | Cancer Care Facilities | Tonsillar Neoplasms - mortality | Tongue Neoplasms - pathology | Pharyngeal Neoplasms - mortality | Analysis of Variance | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Tonsillar Neoplasms - radiotherapy | Tonsillar Neoplasms - drug therapy | Pharyngeal Neoplasms - pathology | Aged | Palatal Neoplasms - drug therapy | Neoplasm Staging | Radiotherapy, Intensity-Modulated | Care and treatment | Throat cancer | Radiotherapy | Nuclear radiation | Cancer | PATIENTS | NEOPLASMS | FAILURES | METASTASES | PLATINUM | RADIATION DOSES | LYMPHATIC SYSTEM | CHEMOTHERAPY | PLANNING | PHARYNX | TONGUE | WOMEN | MEN | RADIOLOGY AND NUCLEAR MEDICINE | NECK | RADIOTHERAPY
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2016, Volume 96, Issue 5, pp. 967 - 975
Abstract Purpose To assess the impact of radiation treatment time (RTT) in head and neck cancers on overall survival (OS) in the era of chemoradiation.... 
Radiology | Hematology, Oncology and Palliative Medicine | ONCOLOGY | CONCURRENT CHEMOTHERAPY | LARYNGEAL-CANCER | THERAPY ONCOLOGY GROUP | SQUAMOUS-CELL CARCINOMA | RANDOMIZED-TRIAL | STANDARD FRACTIONATION | LOCALLY ADVANCED HEAD | 1ST REPORT | PROLONGATION | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Radiotherapy - mortality | Humans | Oropharyngeal Neoplasms - mortality | Chemoradiotherapy - mortality | Hypopharyngeal Neoplasms - mortality | Tongue Neoplasms - drug therapy | Time Factors | Laryngeal Neoplasms - drug therapy | Tongue Neoplasms - radiotherapy | Tongue Neoplasms - mortality | Chemoradiotherapy - methods | Oropharyngeal Neoplasms - drug therapy | Head and Neck Neoplasms - drug therapy | Kaplan-Meier Estimate | Oropharyngeal Neoplasms - radiotherapy | Chi-Square Distribution | Tonsillar Neoplasms - mortality | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Analysis of Variance | Laryngeal Neoplasms - mortality | Tonsillar Neoplasms - radiotherapy | Survival Analysis | Tonsillar Neoplasms - drug therapy | Head and Neck Neoplasms - mortality | Hypopharyngeal Neoplasms - drug therapy | Care and treatment | Cancer patients | Radiotherapy | Patient outcomes | Radiation | Cancer | HEAD | PATIENTS | SURVIVAL TIME | NEOPLASMS | RADIOLOGY AND NUCLEAR MEDICINE | NECK | LYMPHATIC SYSTEM | CHEMOTHERAPY | Head and Neck Cancer | Treatment time | National Cancer Database | Squamous Cell
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2010, Volume 76, Issue 5, pp. 1360 - 1368
Purpose The aim of this study was to investigate prospectively the weekly volume changes in the target volumes and organs at risk and the resulting dosimetric... 
Radiology | Hematology, Oncology and Palliative Medicine | Head and neck cancer | Volume changes | Chemo-IMRT | Dosimetric changes | SYSTEM | DELINEATION | IMRT | ONCOLOGY | GUIDELINES | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Prospective Studies | Humans | Oropharyngeal Neoplasms - diagnostic imaging | Spinal Cord - radiation effects | Laryngeal Neoplasms - diagnostic imaging | Oropharyngeal Neoplasms - pathology | Cisplatin - administration & dosage | Laryngeal Neoplasms - pathology | Nasopharyngeal Neoplasms - pathology | Nasopharyngeal Neoplasms - radiotherapy | Fluorouracil - administration & dosage | Time Factors | Laryngeal Neoplasms - drug therapy | Nasopharyngeal Neoplasms - drug therapy | Brain Stem - radiation effects | Radiotherapy Dosage | Nasopharyngeal Neoplasms - diagnostic imaging | Oropharyngeal Neoplasms - drug therapy | Parotid Gland - diagnostic imaging | Head and Neck Neoplasms - diagnostic imaging | Radiotherapy, Intensity-Modulated - methods | Head and Neck Neoplasms - drug therapy | Oropharyngeal Neoplasms - radiotherapy | Tumor Burden | Head and Neck Neoplasms - pathology | Radiography | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Parotid Gland - radiation effects | Hypopharyngeal Neoplasms - pathology | Combined Modality Therapy - methods | Hypopharyngeal Neoplasms - drug therapy | Hypopharyngeal Neoplasms - diagnostic imaging | Care and treatment | Chemotherapy | Oncology, Experimental | Radiation | Research | Radiotherapy | Cancer | TOMOGRAPHY | HEAD | DIAGNOSTIC TECHNIQUES | NEOPLASMS | RADIATION DOSES | MEDICINE | COMPUTERIZED TOMOGRAPHY | CHEMOTHERAPY | NUCLEAR MEDICINE | CAT SCANNING | DISEASES | THERAPY | DOSES | RADIOLOGY AND NUCLEAR MEDICINE | NECK | BODY | COMBINED THERAPY | RADIOLOGY
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2013, Volume 87, Issue 5, pp. 1078 - 1085
Purpose To compare the temporal lymph node (LN) regression and regional control (RC) after primary chemoradiation therapy/radiation therapy in human... 
Radiology | Hematology, Oncology and Palliative Medicine | METASTASIS | ONCOLOGY | DISSECTION | OROPHARYNGEAL CANCER | LYMPH-NODES | SQUAMOUS-CELL CARCINOMA | CHEMORADIATION | CHEMORADIOTHERAPY | HUMAN-PAPILLOMAVIRUS | RADIOTHERAPY | ONCOLOGY GROUP | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - surgery | Multivariate Analysis | Head and Neck Neoplasms - virology | Lymph Nodes - pathology | Hypopharyngeal Neoplasms - virology | Humans | Middle Aged | Male | Oropharyngeal Neoplasms - pathology | Laryngeal Neoplasms - pathology | Lymph Nodes - radiation effects | Aged, 80 and over | Laryngeal Neoplasms - drug therapy | Adult | Female | Papillomavirus Infections - virology | Remission Induction - methods | Oropharyngeal Neoplasms - drug therapy | Laryngeal Neoplasms - surgery | Head and Neck Neoplasms - drug therapy | Organ Size | Oropharyngeal Neoplasms - radiotherapy | Treatment Outcome | Lymph Nodes - virology | Oropharyngeal Neoplasms - virology | Head and Neck Neoplasms - pathology | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Oropharyngeal Neoplasms - surgery | Hypopharyngeal Neoplasms - pathology | Aged | Combined Modality Therapy - methods | Hypopharyngeal Neoplasms - drug therapy | Neoplasm Staging | Head and Neck Neoplasms - surgery | Cohort Studies | Laryngeal Neoplasms - virology | Neck Dissection | Sects | Care and treatment | Radiotherapy | Nuclear radiation | Papillomavirus infections | Cancer | HEAD | MULTIVARIATE ANALYSIS | NEOPLASMS | LYMPH NODES | POSITRON COMPUTED TOMOGRAPHY | CHARGES | RADIOLOGY AND NUCLEAR MEDICINE | NECK | LARYNX | HAZARDS
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 01/2018, Volume 110, Issue 1, pp. 109 - 120
Background: Cancer-associated fibroblasts (CAFs) are tumor-promoting and correlate with poor survival in many cancers, which has led to their emergence as... 
CELL LUNG-CANCER | PHASE-II TRIAL | OXIDATIVE STRESS | ONCOLOGY | NAB-PACLITAXEL | ACTIVATION PROTEIN | DEPENDENT INVASION | PANCREATIC-CANCER | MONOCLONAL-ANTIBODY | DIFFERENTIATION | STROMAL CELLS | Lung Neoplasms - drug therapy | Up-Regulation | Pyrazoles - therapeutic use | Reactive Oxygen Species - metabolism | Cell Count | Humans | Middle Aged | Male | Oropharyngeal Neoplasms - pathology | Head and Neck Neoplasms - chemistry | RNA Interference | Cancer-Associated Fibroblasts - chemistry | Aged, 80 and over | NADPH Oxidases - genetics | Adenocarcinoma - chemistry | Esophageal Neoplasms - chemistry | Lung Neoplasms - chemistry | NADPH Oxidases - antagonists & inhibitors | Head and Neck Neoplasms - drug therapy | Carcinoma, Squamous Cell - chemistry | Survival Rate | Adenocarcinoma - drug therapy | Disease Progression | Phenotype | Carcinoma, Squamous Cell - drug therapy | Head and Neck Neoplasms - genetics | Mice | Neoplasm Transplantation | Carcinoma, Non-Small-Cell Lung - chemistry | Carcinoma, Squamous Cell - genetics | Colorectal Neoplasms - chemistry | Cell Transdifferentiation - genetics | Myofibroblasts - chemistry | Actins - analysis | Cell Transdifferentiation - drug effects | Adult | Female | Adenocarcinoma - genetics | Cancer-Associated Fibroblasts - physiology | Pyridines - therapeutic use | Lung Neoplasms - genetics | Myofibroblasts - pathology | Carcinoma, Non-Small-Cell Lung - genetics | NADPH Oxidases - analysis | Mouth Neoplasms - chemistry | NADPH Oxidase 4 | Cancer-Associated Fibroblasts - pathology | Animals | Esophageal Neoplasms - genetics | Mouth Neoplasms - pathology | Oropharyngeal Neoplasms - chemistry | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Colorectal Neoplasms - pathology | Esophageal Neoplasms - drug therapy
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2013, Volume 87, Issue 5, pp. 1086 - 1093
Purpose To assess the dosimetric benefit, treatment outcome, and toxicity of high-dose and extended-field intensity modulated radiation therapy (IMRT) in... 
Radiology | Hematology, Oncology and Palliative Medicine | HEAD | NASOPHARYNGEAL CARCINOMA | PROGNOSTIC-FACTORS | ONCOLOGY | NASAL-TYPE | ARC THERAPY | TOXICITY | EXPERIENCE | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | NECK CANCER | CHEMOTHERAPY | Organs at Risk - radiation effects | Pharyngeal Neoplasms - radiotherapy | Humans | Middle Aged | Male | Oropharyngeal Neoplasms - pathology | Pharyngeal Neoplasms - drug therapy | Nasopharyngeal Neoplasms - pathology | Young Adult | Child | Radiotherapy Planning, Computer-Assisted | Lymphatic Irradiation - methods | Radiotherapy, Intensity-Modulated - mortality | Radiotherapy Dosage | Nasopharyngeal Neoplasms - diagnostic imaging | Nose Neoplasms - pathology | Oropharyngeal Neoplasms - drug therapy | Radiotherapy, Intensity-Modulated - methods | Oropharyngeal Neoplasms - radiotherapy | Pharyngeal Neoplasms - diagnostic imaging | Pharyngeal Neoplasms - mortality | Radiography | Lymphoma, Extranodal NK-T-Cell - pathology | Parotid Gland - radiation effects | Adolescent | Organs at Risk - diagnostic imaging | Lymphoma, Extranodal NK-T-Cell - mortality | Pharyngeal Neoplasms - pathology | Xerostomia - etiology | Nasopharyngeal Neoplasms - mortality | Oropharyngeal Neoplasms - diagnostic imaging | Oropharyngeal Neoplasms - mortality | Radiotherapy, Intensity-Modulated - adverse effects | Organ Sparing Treatments - methods | Nasopharyngeal Neoplasms - radiotherapy | Lymphoma, Extranodal NK-T-Cell - drug therapy | Lymphoma, Extranodal NK-T-Cell - radiotherapy | Nose Neoplasms - radiotherapy | Adult | Female | Lymphatic Irradiation - adverse effects | Retrospective Studies | Nasopharyngeal Neoplasms - drug therapy | Neck | Parotid Gland - diagnostic imaging | Neoplasm Invasiveness | Treatment Outcome | Xerostomia - prevention & control | Disease-Free Survival | Lymphoma, Extranodal NK-T-Cell - diagnostic imaging | Care and treatment | Lymphomas | Radiotherapy | Nuclear radiation | Patient outcomes | Index Medicus | LYMPHOMAS | GLANDS | LYMPH NODES | RADIOLOGY AND NUCLEAR MEDICINE | RADIATION DOSES | GY RANGE 10-100 | PLANNING
Journal Article
Science, ISSN 0036-8075, 8/2011, Volume 333, Issue 6046, pp. 1154 - 1157
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2013, Volume 14, Issue 8, pp. 697 - 710
Summary Background Previous trials have shown that anti-EGFR monoclonal antibodies can improve clinical outcomes of patients with recurrent or metastatic... 
Hematology, Oncology and Palliative Medicine | SURVIVAL | P16 | ONCOLOGY | COLORECTAL-CANCER | OROPHARYNGEAL CANCER | HUMAN-PAPILLOMAVIRUS | P16(INK4A) | SUBSET | III TRIAL | COOPERATIVE-ONCOLOGY-GROUP | PLUS FLUOROURACIL | Immunohistochemistry | South America | Head and Neck Neoplasms - virology | Prospective Studies | Carcinoma, Squamous Cell - virology | Humans | Middle Aged | Neoplasm Recurrence, Local - virology | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Neoplasm Recurrence, Local - drug therapy | Male | North America | Cisplatin - administration & dosage | Neoplasm Recurrence, Local - pathology | Head and Neck Neoplasms - chemistry | Neoplasm Metastasis | Carcinoma, Squamous Cell - mortality | Cyclin-Dependent Kinase Inhibitor p16 - analysis | Fluorouracil - administration & dosage | Time Factors | Female | Retrospective Studies | Biomarkers, Tumor - analysis | Europe | Head and Neck Neoplasms - drug therapy | Kaplan-Meier Estimate | Proportional Hazards Models | Carcinoma, Squamous Cell - chemistry | Treatment Outcome | Papillomaviridae - isolation & purification | Neoplasm Recurrence, Local - chemistry | Head and Neck Neoplasms - pathology | Disease-Free Survival | Carcinoma, Squamous Cell - drug therapy | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Asia | Biopsy | Carcinoma, Squamous Cell - secondary | Aged | Head and Neck Neoplasms - mortality | Care and treatment | Relapse | Carcinoma | Monoclonal antibodies | Product development | Metastasis | Cisplatin | Cancer | Diseases | Index Medicus
Journal Article
Laryngoscope, ISSN 0023-852X, 09/2009, Volume 119, Issue 9, pp. 1709 - 1719
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2014, Volume 89, Issue 4, pp. 846 - 853
Background We report the first clinical experience and toxicity of multifield optimization (MFO) intensity modulated proton therapy (IMPT) for patients with... 
Radiology | Hematology, Oncology and Palliative Medicine | SYSTEM | PHOTON | ONCOLOGY | RADIOTHERAPY | PARANASAL SINUS | CANCER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | RADIATION-THERAPY | Uncertainty | Follow-Up Studies | Humans | Middle Aged | Proton Therapy - adverse effects | Male | Carcinoma, Squamous Cell - radiotherapy | Chemoradiotherapy | Radiotherapy, Intensity-Modulated - adverse effects | Tongue Neoplasms - drug therapy | Nasopharyngeal Neoplasms - radiotherapy | Adult | Female | Radiotherapy Setup Errors | Nasopharyngeal Neoplasms - drug therapy | Radiotherapy Planning, Computer-Assisted | Tongue Neoplasms - radiotherapy | Radiotherapy Dosage | Carcinoma, Adenoid Cystic - drug therapy | Oropharyngeal Neoplasms - drug therapy | Radiotherapy, Intensity-Modulated - methods | Head and Neck Neoplasms - drug therapy | Oropharyngeal Neoplasms - radiotherapy | Stomatitis - etiology | Quality Assurance, Health Care | Head and Neck Neoplasms - radiotherapy | Pilot Projects | Carcinoma, Squamous Cell - drug therapy | Aged | Carcinoma, Adenoid Cystic - radiotherapy | Proton Therapy - methods | Xerostomia - etiology | Head and neck tumors | Sects | Care and treatment | Nuclear radiation | Index Medicus | HEAD | MEV RANGE 10-100 | PATIENTS | CLINICAL TRIALS | PROTON BEAMS | SKULL | TOXICITY | MEV RANGE 100-1000 | PLANNING | CARCINOMAS | RADIOLOGY AND NUCLEAR MEDICINE | OPTIMIZATION | NECK
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 79, Issue 2, pp. 429 - 435
Purpose Volumetric modulated arc therapy (RapidArc, Varian Medical Systems) permits the delivery of highly conformal dose distributions. We studied planning... 
Radiology | Hematology, Oncology and Palliative Medicine | Head-and-neck cancer | Locally advanced disease | Volumetric modulated arc therapy | RapidArc | Dose distribution | DYSPHAGIA | IMRT | OROPHARYNGEAL CARCINOMA | VOLUME RESPONSE ANALYSIS | PAROTID-GLAND FUNCTION | MODULATED RADIATION-THERAPY | DELINEATION | ARC | IMPACT | ONCOLOGY | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Radiotherapy Dosage | Organs at Risk - radiation effects | Oropharyngeal Neoplasms - drug therapy | Radiotherapy Planning, Computer-Assisted - methods | Humans | Radiotherapy, Intensity-Modulated - methods | Head and Neck Neoplasms - drug therapy | Oropharyngeal Neoplasms - radiotherapy | Antineoplastic Agents - therapeutic use | Oropharyngeal Neoplasms - pathology | Tumor Burden | Head and Neck Neoplasms - pathology | Laryngeal Neoplasms - pathology | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - pathology | Laryngeal Neoplasms - drug therapy | Combined Modality Therapy - methods | Hypopharyngeal Neoplasms - drug therapy | Phantoms, Imaging | Film Dosimetry | Care and treatment | Cancer patients | Cancer | HEAD | RADIATION DOSE DISTRIBUTIONS | DISEASES | THERAPY | NEOPLASMS | RADIOLOGY AND NUCLEAR MEDICINE | NECK | MEDICINE | BODY | COMBINED THERAPY | DELIVERY | PLANNING
Journal Article