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PLoS pathogens, ISSN 1553-7374, 2013, Volume 9, Issue 11, p. e1003773
.... They can be induced by viral infection, are secreted and bind to specific receptors on the same or neighbouring cells to activate the expression of hundreds of IFN stimulated genes (ISGs... 
CELLS | DEFENSE | VIRUS-INFECTION | DISTINCT | RIG-I | MICROBIOLOGY | IRF-7 | ANTIVIRAL RESPONSE | VIROLOGY | GENE | SIGNALING PATHWAY | ADAPTER PROTEIN | PARASITOLOGY | Epithelial Cells - metabolism | Influenza A virus - genetics | Respiratory Mucosa - virology | Interferon Regulatory Factor-7 - genetics | Interferon Type I - immunology | Interferon Regulatory Factor-3 - genetics | Interleukins - metabolism | Orthomyxoviridae Infections - genetics | Respiratory Mucosa - pathology | Interleukins - genetics | Interleukins - immunology | Respiratory Mucosa - immunology | Adaptor Proteins, Signal Transducing - immunology | Interferon Type I - metabolism | Influenza A virus - immunology | Membrane Proteins - metabolism | Interferon Regulatory Factor-3 - immunology | Nerve Tissue Proteins - immunology | Membrane Proteins - genetics | Orthomyxoviridae Infections - metabolism | Epithelial Cells - pathology | Membrane Proteins - immunology | Interferon Regulatory Factor-7 - immunology | Interferon Regulatory Factor-7 - metabolism | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Influenza A virus - metabolism | Epithelial Cells - immunology | Epithelial Cells - virology | Adaptor Proteins, Signal Transducing - genetics | Interferon Regulatory Factor-3 - metabolism | Interferon Type I - genetics | Mice | Respiratory Mucosa - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Orthomyxoviridae Infections - immunology | Epithelial cells | Influenza | Physiological aspects | Host-parasite relationships | Interferon | Genetic aspects | Genetic transcription | Research | Health aspects | Airway (Medicine) | Interleukins/metabolism | Nerve Tissue Proteins/immunology | Orthomyxoviridae Infections/genetics | Orthomyxoviridae Infections/metabolism | Membrane Proteins/genetics | Adaptor Proteins, Signal Transducing/genetics | Interferon Regulatory Factor-7/genetics | Interleukins/immunology | Membrane Proteins/immunology | Life Sciences | Orthomyxoviridae Infections/immunology | Influenza A virus/genetics | Nerve Tissue Proteins/metabolism | Respiratory Mucosa/immunology | Immunology | Interferon Type I/immunology | Epithelial Cells/immunology | Epithelial Cells/virology | Interferon Regulatory Factor-7/immunology | Epithelial Cells/metabolism | Interferon Regulatory Factor-3/immunology | Respiratory Mucosa/pathology | Influenza A virus/immunology | Interleukins/genetics | Interferon Regulatory Factor-3/genetics | Influenza A virus/metabolism | Adaptor Proteins, Signal Transducing/metabolism | Epithelial Cells/pathology | Adaptor Proteins, Signal Transducing/immunology | Interferon Type I/genetics | Interferon Regulatory Factor-3/metabolism | Membrane Proteins/metabolism | Nerve Tissue Proteins/genetics | Interferon Regulatory Factor-7/metabolism | Interferon Type I/metabolism | Respiratory Mucosa/metabolism | Respiratory Mucosa/virology | Cytokines | Genes | Rodents | Genomics | Genomes | Kinases | Experiments | Viral infections
Journal Article
PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 9, p. e0184976
Respiratory tract infections such as flu cause severe morbidity and mortality and are among the leading causes of death in children and adults worldwide... 
BACTERIA | EFFICACY | VIRUS INFECTION | MULTIDISCIPLINARY SCIENCES | FERMENTED DAIRY PRODUCT | PROBIOTICS | MICROBIOTA | INNATE LYMPHOID-CELLS | DURATION | CONSUMPTION | CASEI DN-114 001 | Orthomyxoviridae Infections - prevention & control | Probiotics - administration & dosage | Orthomyxoviridae Infections - microbiology | Respiratory Tract Infections - prevention & control | Colony Count, Microbial | Orthomyxoviridae - immunology | Respiratory Tract Infections - microbiology | Immunity, Cellular - immunology | Animals | Respiratory Tract Infections - immunology | Female | Mice | Mice, Inbred BALB C | Lactobacillus paracasei - physiology | Orthomyxoviridae Infections - immunology | Probiotics | Care and treatment | Immune response | Influenza | Physiological aspects | Development and progression | Research | Lactobacillus | Laboratories | Immune clearance | Homeostasis | Infections | Genomes | Multivariate analysis | Immunity | Modulators | Accumulation | Respiratory tract | Intestine | Bacteria | Respiratory tract diseases | Children | Bioinformatics | Myeloid cells | Bacterial infections | Immunomodulation | Lactobacilli | Peptidoglycans | Inflammation | Gene expression | Morbidity | Feeding | Lungs | Adults | Methods | Viral infections | Immunity, Cellular/immunology | Respiratory Tract Infections/immunology | Orthomyxoviridae Infections/prevention & control | Probiotics/administration & dosage | Respiratory Tract Infections/prevention & control | Orthomyxoviridae/immunology | Life Sciences | Orthomyxoviridae Infections/immunology | Human health and pathology | Infectious diseases | Respiratory Tract Infections/microbiology | Food and Nutrition | Orthomyxoviridae Infections/microbiology | Lactobacillus paracasei/physiology
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 9/2009, Volume 325, Issue 5945, pp. 1265 - 1269
The magnitude of antigen-specific CD8⁺T cell responses is not fixed but correlates with the severity of infection... 
T lymphocytes | Pathogens | Antigens | Bar codes | T lymphoid precursor cells | Reports | Infections | Dosage | Immunity | T cell antigen receptors | Daughter cells | Ovalbumin/immunology | Epitopes/immunology | Molecular Sequence Data | Listeriosis/drug therapy | Adoptive Transfer | Genes, T-Cell Receptor beta | Antigens/immunology | CD8-Positive T-Lymphocytes/immunology | Orthomyxoviridae Infections/immunology | Vaccinia/immunology | Antigens, Viral/immunology | Receptors, Antigen, T-Cell, alpha-beta/chemistry | Virus Diseases/immunology | Influenza A virus/immunology | Lymphocyte Activation | Mice, Inbred C57BL | Mice, Transgenic | Spleen/immunology | Ampicillin/therapeutic use | Animals | Genes, T-Cell Receptor alpha | Lymphocyte Count | Dendritic Cells/immunology | Mice | Antigens, Bacterial/immunology | Anti-Bacterial Agents/therapeutic use | REPERTOIRE | MAGNITUDE | AFFINITY | BINDING | MULTIDISCIPLINARY SCIENCES | Listeriosis - drug therapy | Spleen - immunology | Ovalbumin - immunology | Dendritic Cells - immunology | Receptors, Antigen, T-Cell, alpha-beta - chemistry | Antigens, Bacterial - immunology | Receptors, Antigen, T-Cell, alpha-beta - immunology | Epitopes - immunology | Anti-Bacterial Agents - therapeutic use | Listeriosis - immunology | Influenza A virus - immunology | Ampicillin - therapeutic use | Virus Diseases - immunology | Antigens, Viral - immunology | Vaccinia - immunology | Antigens - immunology | CD8-Positive T-Lymphocytes - immunology | Orthomyxoviridae Infections - immunology | Cellular biology | Lymphocytes | Immune system
Journal Article
The Journal of experimental medicine, ISSN 0022-1007, 06/2010, Volume 207, Issue 6, pp. 1235 - 46
Journal Article
Journal of virology, ISSN 0022-538X, 2013, Volume 87, Issue 12, pp. 6911 - 6924
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2014, Volume 211, Issue 12, pp. 2397 - 2410
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2014, Volume 193, Issue 10, pp. 5108 - 5117
.... Lung Ag-specific CD8(+) T cells (T-CD8) are impaired during acute viral lower respiratory infection by the inhibitory receptor programmed death-1 (PD-1... 
PROTECTIVE IMMUNITY | HUMAN METAPNEUMOVIRUS INFECTION | FUSION PROTEIN | FUNCTIONAL IMPAIRMENT | INHIBITORY RECEPTORS | INFLUENZA-VIRUS | IMMUNOLOGY | CHRONIC VIRAL-INFECTION | SYNCYTIAL VIRUS | RAT SIGMODON-HISPIDUS | TRACT INFECTIONS | Antigens, CD - immunology | CD8-Positive T-Lymphocytes - pathology | Humans | Paramyxoviridae Infections - genetics | Antigens, CD - genetics | Respiratory Tract Infections - genetics | Viral Load | Orthomyxoviridae - immunology | Orthomyxoviridae Infections - genetics | Lung - virology | Paramyxoviridae Infections - virology | B-Lymphocytes - pathology | Receptors, Immunologic - immunology | Respiratory Tract Infections - virology | Respiratory Tract Infections - pathology | Metapneumovirus - immunology | Lung - pathology | Signal Transduction | Orthomyxoviridae Infections - pathology | Gene Expression Regulation | Signaling Lymphocytic Activation Molecule Family | Cell Degranulation - immunology | Viral Vaccines - administration & dosage | Paramyxoviridae Infections - immunology | Animals | B-Lymphocytes - immunology | Immune Evasion | Virus Replication | CD8-Positive T-Lymphocytes - virology | Respiratory Tract Infections - immunology | Lymphocyte Count | Mice | Paramyxoviridae Infections - prevention & control | Programmed Cell Death 1 Receptor - immunology | CD8-Positive T-Lymphocytes - immunology | Receptors, Immunologic - genetics | Orthomyxoviridae Infections - virology | Programmed Cell Death 1 Receptor - genetics | Viral Vaccines - immunology | Lung - immunology | Orthomyxoviridae Infections - immunology
Journal Article
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2011, Volume 333, Issue 6044, pp. 843 - 850
.... Here, we report the isolation and characterization of a human monoclonal antibody CR8020 with broad neutralizing activity against most group 2 viruses, including H3N2 and H7N7, which cause severe human infection... 
Influenza A virus | RESEARCH ARTICLES | Vaccination | Cardiopulmonary resuscitation | Antibodies | Viruses | Orthomyxoviridae | Infections | Epitopes | H3N2 subtype influenza A virus | Crystal structure | FUSION | HEMAGGLUTININ | RECOGNITION | AVIAN INFLUENZA | SUBTYPES | MULTIDISCIPLINARY SCIENCES | PH | VACCINATION | MONOCLONAL-ANTIBODIES | PEPTIDE | SEASON | Orthomyxoviridae Infections - prevention & control | Antibody Specificity | Humans | Molecular Sequence Data | Antigens, Viral - genetics | Crystallography, X-Ray | Neutralization Tests | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Epitopes - immunology | Antibodies, Neutralizing - immunology | Conserved Sequence | Influenza A Virus, H7N7 Subtype - immunology | Influenza A virus - immunology | Influenza, Human - therapy | Antibodies, Monoclonal - immunology | Amino Acid Sequence | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Models, Molecular | Antigens, Viral - chemistry | Antibodies, Monoclonal - isolation & purification | Influenza A Virus, H3N2 Subtype - immunology | Antibodies, Viral - isolation & purification | Antibodies, Neutralizing - isolation & purification | Antigens, Viral - immunology | Animals | Influenza Vaccines - immunology | Antibodies, Viral - immunology | Protein Conformation | Mice | Influenza A Virus, H7N7 Subtype - genetics | Mutation | Binding Sites, Antibody | Influenza, Human - prevention & control | Orthomyxoviridae Infections - immunology | Influenza, Human - immunology | Influenza viruses | Influenza vaccines | Crystals | Monoclonal antibodies | Physiological aspects | Research | Properties | Structure | Vaccines | Influenza | Public health | Virology | fusion | peptide | avian influenza | hemagglutinin | recognition | monoclonal-antibodies | season | vaccination | subtypes
Journal Article