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Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2017, Volume 198, Issue 11, pp. 4383 - 4393
The absent in melanoma 2 (AIM2) inflammasome plays an important role in many viral and bacterial infections, but very little is known about its role in... 
ACTIVATION | REPLICATION | ALVEOLAR EPITHELIAL-CELLS | DNA | MACROPHAGES | A VIRUS-INFECTION | II CELLS | NLRP3 INFLAMMASOME | IMMUNOLOGY | RESPIRATORY-DISTRESS-SYNDROME | INNATE IMMUNITY | RNA, Small Interfering - genetics | Orthomyxoviridae Infections - physiopathology | Humans | Caspase 1 - immunology | Interleukin-1beta - genetics | DNA-Binding Proteins - deficiency | Lung Injury - virology | Influenza, Human - mortality | Influenza A virus - immunology | Influenza, Human - physiopathology | Macrophages, Alveolar - immunology | Adaptive Immunity | Macrophages, Alveolar - virology | DNA-Binding Proteins - physiology | Interleukin-1beta - immunology | DNA-Binding Proteins - genetics | Viral Load - immunology | Mice, Knockout | Lung Injury - physiopathology | Animals | Orthomyxoviridae Infections - mortality | Caspase 1 - genetics | Caspase 1 - secretion | Inflammasomes - immunology | Mice | Lung Injury - immunology | Orthomyxoviridae Infections - virology | Orthomyxoviridae Infections - immunology | Influenza, Human - immunology | Transcription | Viruses | Infections | Macrophages | Caspase-1 | Rodents | Bacteria | Alveoli | Injuries | Immune system | RNA viruses | Immune response | Bacterial infections | Mortality | Melanoma | Caspase | Inflammation | siRNA | IL-1β | Ribonucleic acid--RNA | Morbidity | Lungs | Influenza | In vivo methods and tests | Infectious Disease and Host Response
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2016, Volume 113, Issue 3, pp. E368 - E377
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 01/2013, Volume 187, Issue 1, pp. 65 - 77
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 2/2006, Volume 193, Issue 3, pp. 387 - 395
Journal Article
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 05/2010, Volume 11, Issue 5, pp. 404 - 410
Influenza virus, a negative-stranded RNA virus that causes severe illness in humans and animals, stimulates the inflammasome through the Nod-like receptor... 
A VIRUS | STRANDED-RNA | PROTEIN | CASPASE-1 | IMMUNE-RESPONSES | INNATE | RIG-I | INFECTION | IMMUNOLOGY | NALP3 INFLAMMASOME | CYTOPLASMIC DNA | Membrane Glycoproteins - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Golgi Apparatus - drug effects | Ion Channels - genetics | Protein Transport - drug effects | Hydrogen-Ion Concentration - drug effects | Viral Matrix Proteins - metabolism | Cytokines - genetics | Carrier Proteins - immunology | Toll-Like Receptor 7 - metabolism | Macrophages - pathology | Monensin - pharmacology | Mice, Knockout | Macrophages - metabolism | Genetic Engineering | Mice | Viral Matrix Proteins - immunology | Orthomyxoviridae - physiology | Ion Channels - immunology | Protons | Viral Matrix Proteins - genetics | Orthomyxoviridae Infections - physiopathology | Dendritic Cells - pathology | Oncogene Proteins, Viral - pharmacology | Golgi Apparatus - virology | Macrophages - virology | Potassium Chloride - pharmacology | Toll-Like Receptor 7 - immunology | Dendritic Cells - drug effects | Membrane Glycoproteins - immunology | Dendritic Cells - virology | Dendritic Cells - metabolism | Macrophages - immunology | Toll-Like Receptor 7 - genetics | Cytokines - metabolism | Mice, Inbred C57BL | Cells, Cultured | Membrane Glycoproteins - genetics | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Ion Channels - metabolism | Virus Replication | Golgi Apparatus - metabolism | Macrophages - drug effects | Orthomyxoviridae - pathogenicity | Orthomyxoviridae Infections - immunology | Sequence Deletion - genetics | Influenza viruses | Receptors | Viral proteins | Physiological aspects | Viruses | Ion channels | Research | Health aspects
Journal Article