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Journal Article
Journal Article
Journal Article
Science, ISSN 0036-8075, 7/2012, Volume 337, Issue 6091, pp. 199 - 204
Influenza A virus (IAV) infection leads to variable and imperfectly understood pathogenicity. We report that segment 3 of the virus contains a second open... 
Proteins | Messenger RNA | RNA | Lungs | RESEARCH ARTICLES | Viruses | Infections | Open reading frames | Gene expression | Codons | Genetic mutation | SYSTEM | PA SUBUNIT | ENDONUCLEASE | MULTIDISCIPLINARY SCIENCES | SIGNALS | DEGRADATION | INFECTION | SUPPRESSION | BINDING | CELL-DEATH | Humans | Influenza A virus - genetics | RNA Replicase - metabolism | Reassortant Viruses - genetics | RNA, Messenger - metabolism | Viral Proteins - metabolism | Orthomyxoviridae Infections - genetics | Base Sequence | Repressor Proteins - metabolism | Amino Acid Sequence | RNA Replicase - genetics | Viral Proteins - chemistry | Orthomyxoviridae Infections - pathology | Repressor Proteins - genetics | Viral Proteins - genetics | Proteome | Influenza A virus - metabolism | Viral Nonstructural Proteins - metabolism | Mice | Mice, Inbred BALB C | Mutation | Orthomyxoviridae Infections - virology | Open Reading Frames | Molecular Sequence Data | Influenza A Virus, H1N1 Subtype - growth & development | Lung - virology | Viral Nonstructural Proteins - chemistry | Codon | Frameshifting, Ribosomal | RNA, Viral - genetics | HEK293 Cells | Conserved Sequence | Female | Protein Interaction Domains and Motifs | RNA, Viral - metabolism | Influenza A Virus, H1N1 Subtype - genetics | Viral Proteins - biosynthesis | Cell Line | Genome, Viral | Lung - pathology | Repressor Proteins - chemistry | RNA, Messenger - genetics | Gene Expression Regulation | Viral Nonstructural Proteins - genetics | Influenza A Virus, H1N1 Subtype - pathogenicity | Animals | Virus Replication | RNA Replicase - chemistry | Orthomyxoviridae Infections - immunology | Pathology | Genetic aspects | Research | Influenza | Influenza research | Pathogenesis | Virology | Ribonucleic acids | Genes | Molecular interactions | Segments | Genomes | Constraining
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2009, Volume 206, Issue 1, pp. 79 - 87
Influenza virus infection is recognized by the innate immune system through Toll like receptor (TLR) 7 and retinoic acid inducible gene I. These two... 
MEDICINE, RESEARCH & EXPERIMENTAL | STRANDED-RNA | DYING CELLS | HUMAN MACROPHAGES | INTERLEUKIN-1-BETA | INFECTION | IMMUNOLOGY | A-VIRUS | CASPASE-1 ACTIVATION | CRYOPYRIN/NALP3 | T-CELLS | NALP3 INFLAMMASOME | CD8-Positive T-Lymphocytes - cytology | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Receptors, Interleukin-1 - genetics | Immunity, Innate - genetics | Cell Movement - genetics | Orthomyxoviridae - immunology | Orthomyxoviridae Infections - genetics | CD4-Positive T-Lymphocytes - immunology | Cell Movement - immunology | Lung - virology | Interleukin-1beta - metabolism | Apoptosis Regulatory Proteins - genetics | Lung - metabolism | Dendritic Cells - virology | Dendritic Cells - metabolism | Macrophages, Alveolar - immunology | Macrophages, Alveolar - virology | Antibody Formation - immunology | Immunity, Cellular - genetics | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | Mice, Knockout | Carrier Proteins - genetics | Immunity, Cellular - immunology | Immunity, Innate - immunology | Immunoglobulin Isotypes - blood | Animals | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Survival Analysis | Nasal Lavage Fluid - immunology | Immunoglobulin Isotypes - immunology | Mice | Macrophages, Alveolar - metabolism | CD8-Positive T-Lymphocytes - immunology | Orthomyxoviridae Infections - virology | Lung - immunology | Orthomyxoviridae Infections - immunology | Calcium-Binding Proteins - genetics | Multiprotein Complexes - immunology | Brief Definitive Reports
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2010, Volume 107, Issue 4, pp. 1512 - 1517
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 06/2014, Volume 111, Issue 25, pp. E2514 - E2523
Journal Article
Nature Immunology, ISSN 1529-2908, 06/2013, Volume 14, Issue 6, pp. 593 - 602
We found upregulation of expression of the microRNA miR-155 in primary effector and effector memory CD8(+) T cells, but low miR-155 expression in naive and... 
IFN | MEMORY | CLONAL EXPANSION | STAT3 | PROLIFERATION | INFECTION | DIFFERENTIATION | IMMUNOLOGY | MODULATION | CUTTING EDGE | LYMPHOCYTES | Oligonucleotide Array Sequence Analysis | Suppressor of Cytokine Signaling 1 Protein | Immunoblotting | MicroRNAs - metabolism | Gene Expression Profiling | Interferon Regulatory Factor-7 - genetics | Interferons - immunology | Orthomyxoviridae - immunology | Orthomyxoviridae Infections - genetics | Signal Transduction - immunology | STAT1 Transcription Factor - metabolism | Flow Cytometry | RNA Interference | CD8-Positive T-Lymphocytes - metabolism | Gene Regulatory Networks - immunology | Immunologic Memory - genetics | Immunologic Memory - immunology | Gene Regulatory Networks - genetics | Interferons - pharmacology | Suppressor of Cytokine Signaling Proteins - immunology | Mice, Inbred C57BL | Suppressor of Cytokine Signaling Proteins - genetics | Interferon Regulatory Factor-7 - immunology | Signal Transduction - genetics | MicroRNAs - immunology | Reverse Transcriptase Polymerase Chain Reaction | STAT1 Transcription Factor - genetics | Interferon Regulatory Factor-7 - metabolism | STAT1 Transcription Factor - immunology | Mice, Knockout | Animals | Interferons - metabolism | Cell Proliferation - drug effects | Mice | MicroRNAs - genetics | Suppressor of Cytokine Signaling Proteins - metabolism | CD8-Positive T-Lymphocytes - immunology | Orthomyxoviridae Infections - virology | Orthomyxoviridae Infections - immunology
Journal Article
Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 566 - 579
Cigarette smoking is a major risk factor for chronic obstructive pulmonary disease and is presumed to be central to the altered responsiveness to... 
IL-1-LIKE CYTOKINE IL-33 | OBSTRUCTIVE PULMONARY-DISEASE | NK CELLS | IMMUNE-RESPONSES | EFFECTOR FUNCTION | MAST-CELLS | AIRWAY INFLAMMATION | MICE | INFLUENZA-VIRUS | IMMUNOLOGY | T-CELLS | Interleukin-1 Receptor-Like 1 Protein | Respiratory Mucosa - drug effects | Humans | Receptors, Interleukin - deficiency | Killer Cells, Natural - pathology | Pulmonary Disease, Chronic Obstructive - pathology | Orthomyxoviridae Infections - genetics | Respiratory Mucosa - pathology | Interleukins - genetics | Lymphocytes - immunology | Interleukins - immunology | Respiratory Mucosa - immunology | Killer Cells, Natural - immunology | Female | Influenza A virus - immunology | Macrophages - immunology | Pulmonary Disease, Chronic Obstructive - genetics | Lung - pathology | Immunity, Innate - drug effects | Macrophages - pathology | Receptors, Interleukin - immunology | Signal Transduction | Interleukin-33 | Smoke - adverse effects | Orthomyxoviridae Infections - pathology | Gene Expression Regulation | Mice, Transgenic | Receptors, Interleukin - genetics | Lymphocytes - pathology | Animals | Weight Loss | Lung - drug effects | Lymphocytes - drug effects | Interleukins - deficiency | Tobacco - chemistry | Orthomyxoviridae Infections - etiology | Pulmonary Disease, Chronic Obstructive - immunology | Lung - immunology | Orthomyxoviridae Infections - immunology | Virus diseases | Autoimmunity | Lung diseases, Obstructive | Interleukins | Inflammation | Health aspects | Smoking | Disease | Cytokines | Mortality | Infections | Cigarettes | Experiments | Proteins | Influenza | Gangrene | Tumor necrosis factor-TNF | Chronic obstructive pulmonary disease | Viral infections | Basic Medicine | Immunologi inom det medicinska området | Medical and Health Sciences | Medicin och hälsovetenskap | Immunology in the medical area | Medicinska och farmaceutiska grundvetenskaper
Journal Article