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Annals of the Rheumatic Diseases, ISSN 0003-4967, 11/2018, Volume 77, Issue 11, pp. 1636 - 1643
ObjectivesRecent studies indicate that glucose metabolism is altered in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS). Hexokinases (HKs)... 
autoimmune diseases | fibroblasts | inflammation | rheumatoid arthritis | CELLS | STIMULATING FACTOR PRODUCTION | CYTOKINES | DISEASES | CHRONIC INFLAMMATORY ARTHRITIS | ALPHA | RHEUMATOLOGY | EXPRESSION | Synoviocytes - physiology | RNA, Small Interfering - genetics | Arthritis, Experimental - genetics | Synovial Membrane - enzymology | Humans | Gene Expression Regulation | Arthritis, Rheumatoid - enzymology | Mice, Transgenic | Synoviocytes - enzymology | Cell Movement - physiology | Osteoarthritis - genetics | Arthritis, Rheumatoid - pathology | Synovitis - pathology | Arthritis, Experimental - pathology | Osteoarthritis - enzymology | Arthritis, Rheumatoid - genetics | Animals | Synovitis - enzymology | Inflammation Mediators - metabolism | Arthritis, Experimental - enzymology | Osteoarthritis - pathology | Hexokinase - genetics | Hexokinase - metabolism | Knee | Immunohistochemistry | Collagen (type I) | Cell adhesion & migration | Cartilage | Glucose metabolism | Genotype & phenotype | Granulocytes | Fibroblasts | Tumor necrosis factor-TNF | Phenotypes | Cytokines | Rheumatology | Inflammation | siRNA | Metabolism | Gene expression | Synoviocytes | Hexokinase | Rheumatoid arthritis | Glycolysis | Hypoxia | TNF inhibitors | Lactic acid | Osteoarthritis | Cell migration | Cancer | Hypertrophy | Cartilage diseases | Index Medicus
Journal Article
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 08/2010, Volume 69, Issue 8, pp. 1502 - 1510
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 11/2007, Volume 22, Issue 11, pp. 1700 - 1710
We report three novel inhibitors of the physiological pyrophosphatase activity of alkaline phosphatase and show that these compounds are capable of reducing... 
chemical library screening | docking | computer modeling | pyrophosphatase | druggable target | vascular calcification | Vascular calcification | Docking | Druggable target | Chemical library screening | Pyrophosphatase | Computer modeling | MATRIX VESICLES | CALCIFIABLE VESICLES | INFANTILE ARTERIAL CALCIFICATION | OSTEOPONTIN | INORGANIC PYROPHOSPHATE | MINERALIZATION | ENDOCRINOLOGY & METABOLISM | MICE | BETA-GLYCEROPHOSPHATE | ANK | LEVAMISOLE | Triazoles - chemistry | Humans | Imidazoles - chemistry | Pyrophosphatases - genetics | Imidazoles - pharmacokinetics | Osteoarthritis - enzymology | Enzyme Inhibitors - pharmacokinetics | Mice, Mutant Strains | Enzyme Inhibitors - chemistry | Triazines - chemistry | Triazoles - pharmacokinetics | Aortic Diseases - enzymology | Myocytes, Smooth Muscle - drug effects | Binding Sites | Muscle, Smooth, Vascular - drug effects | Triazines - pharmacology | Myocytes, Smooth Muscle - enzymology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | Phosphoric Diester Hydrolases - genetics | Calcinosis - enzymology | Muscle, Smooth, Vascular - cytology | Triazoles - pharmacology | Alkaline Phosphatase - antagonists & inhibitors | Animals | Mice | Calcinosis - pathology | Muscle, Smooth, Vascular - enzymology | Triazines - pharmacokinetics | Index Medicus
Journal Article
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 04/2017, Volume 21, Issue 4, pp. 781 - 790
To probe the role of protein arginine methyltransferase 5 ( PRMT 5) in regulating inflammation, cell proliferation, migration and invasion of fibroblast‐like... 
migration | protein arginine methyltransferases 5 | inflammation | rheumatoid arthritis | fibroblast‐like synoviocytes | fibroblast-like synoviocytes | MEDICINE, RESEARCH & EXPERIMENTAL | PRMT5 | METHYLATION | TISSUE | CELL BIOLOGY | GROWTH | SUPPRESSES | MUTATIONS | EXPRESSION | KINASES | Inflammation - pathology | Fibroblasts - enzymology | Humans | Protein-Arginine N-Methyltransferases - antagonists & inhibitors | NF-kappa B - metabolism | Synoviocytes - enzymology | Synoviocytes - drug effects | Osteoarthritis - enzymology | Inflammation - complications | I-kappa B Kinase - metabolism | Inflammation Mediators - metabolism | Osteoarthritis - pathology | Proto-Oncogene Proteins c-akt - metabolism | Arthritis, Rheumatoid - enzymology | Up-Regulation - genetics | Enzyme Activation - drug effects | Fibroblasts - pathology | Arthritis, Rheumatoid - pathology | Protein-Arginine N-Methyltransferases - metabolism | Up-Regulation - drug effects | Cell Movement - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Fibroblasts - drug effects | Synoviocytes - pathology | Cell Proliferation - drug effects | Inflammation - enzymology | Rheumatoid factor | Methyltransferases | Arginine | Inflammation | Gene expression | Osteoarthritis | Enzyme-linked immunosorbent assay | Proteins | Fibroblasts | Cell growth | Kinases | Rheumatoid arthritis | Cell proliferation | Phosphorylation | Boyden chamber | Lung cancer | AKT protein | Arthritis | Joint surgery | Signal transduction | Biomedical materials | Inhibition | Enzymes | Excretion | RNA-mediated interference | Protein arginine methyltransferase | siRNA | Synoviocytes | Polymerase chain reaction | Studies | Tumor necrosis factor | Immunofluorescence | Cell migration | Index Medicus | Original
Journal Article
Rheumatology (Oxford, England), ISSN 1462-0324, 12/2014, Volume 53, Issue 12, pp. 2270 - 2279
Journal Article
Journal of Biomechanics, ISSN 0021-9290, 2015, Volume 48, Issue 8, pp. 1461 - 1468
Journal Article