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Nature, ISSN 0028-0836, 08/2010, Volume 466, Issue 7308, pp. 829 - 834
The cellular constituents forming the haematopoietic stem cell (HSC) niche in the bone marrow are unclear, with studies implicating osteoblasts, endothelial... 
PROGENITOR CELLS | OSTEOBLAST | OSTEOPONTIN | MICROENVIRONMENT | MULTIDISCIPLINARY SCIENCES | SELF-RENEWAL | RECEPTOR | DIFFERENTIATION | NEURAL CREST | COOPERATION | EXPRESSION | Chondrocytes - cytology | Nestin | Multipotent Stem Cells - metabolism | Parathyroid Hormone - pharmacology | Cell Lineage - drug effects | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Multipotent Stem Cells - drug effects | Sympathetic Nervous System - physiology | Cell Division | Stromal Cells - drug effects | Osteoblasts - cytology | Hematopoietic Stem Cells - drug effects | Mesenchymal Stromal Cells - drug effects | Gene Expression Regulation - genetics | Osteoblasts - drug effects | Stromal Cells - metabolism | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Mice, Transgenic | Hematopoietic Stem Cells - metabolism | Stem Cell Niche - cytology | Nerve Tissue Proteins - metabolism | Granulocyte Colony-Stimulating Factor - pharmacology | Animals | Chemokine CXCL12 - metabolism | Cell Differentiation - drug effects | Multipotent Stem Cells - cytology | Hematopoietic Stem Cells - cytology | Stem Cell Niche - metabolism | Mice | Stem Cell Niche - drug effects | Osteoblasts - metabolism | Intermediate Filament Proteins - metabolism | Mesenchymal Stem Cell Transplantation | Stromal Cells - cytology | Cell Movement | Physiological aspects | Genetic aspects | Research | Bone marrow cells | Gene expression | Osteoblasts | Hematopoietic stem cells | Studies | Proteins | Bone marrow | Rodents | Stem cells | Index Medicus
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 04/2009, Volume 24, Issue 4, pp. 578 - 588
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 13, pp. 3467 - 3478
Abstract Titanium implants having enhanced osteogenic activity and antibacterial property are highly desirable for the prevention of implant associated... 
Advanced Basic Science | Dentistry | Antibacterial property | Osteogenic differentiation | Zinc | Mesenchymal stem cells | Titania nanotubes | ACTIVATION | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | OSSEOINTEGRATION | IMPLANTS | HYDROXYAPATITE | IN-VITRO | OSTEOBLAST FUNCTIONS | BONE | BACTERIAL ADHESION | EXPRESSION | L-Lactate Dehydrogenase - metabolism | Mesenchymal Stromal Cells - enzymology | Titanium - pharmacology | Alkaline Phosphatase - metabolism | Extracellular Matrix - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Microbial Sensitivity Tests | Nanotubes - chemistry | Mesenchymal Stromal Cells - cytology | Absorption | Mesenchymal Stromal Cells - ultrastructure | Surface Properties | Cell Death - drug effects | Bacterial Adhesion - drug effects | Nanotubes - ultrastructure | Mesenchymal Stromal Cells - drug effects | Calcification, Physiologic - drug effects | Extracellular Matrix - drug effects | Osteogenesis - drug effects | Rats | Cell Adhesion - drug effects | Rats, Sprague-Dawley | Cell Shape - drug effects | Animals | MAP Kinase Signaling System - drug effects | Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Zinc - pharmacology | Staphylococcus aureus - drug effects | Zinc compounds | Antibacterial agents | Nanotubes | Index Medicus | Surgical implants | Biomedical materials | Titanium | Biocompatibility | Nanostructure | Coatings | Titanium dioxide
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 8, pp. 3143 - 3148
The endocrine hormone fibroblast growth factor 21 (FGF21) is a powerful modulator of glucose and lipid metabolism and a promising drug for type 2 diabetes.... 
Bone resorption | Bone formation | Bone marrow | Bones | Osteoclasts | Fibroblast growth factors | Gene expression regulation | Adipocytes | Type 2 diabetes mellitus | Osteoblasts | Osteoblast | Adipocyte | Nuclear receptor | Bone metabolism | Thiazolidinediones | thiazolidinediones | FIBROBLAST-GROWTH-FACTOR-21 | MULTIDISCIPLINARY SCIENCES | ALPHA | osteoblast | ADIPOGENESIS | INSULIN SENSITIVITY | OSTEOCLAST | bone metabolism | METABOLISM | adipocyte | nuclear receptor | PPAR-GAMMA | MICE | ROSIGLITAZONE | FGF21 | Bone and Bones - pathology | RANK Ligand - metabolism | Adipogenesis - drug effects | Humans | PPAR gamma - metabolism | Bone and Bones - drug effects | Fibroblast Growth Factors - metabolism | Fibroblast Growth Factors - administration & dosage | Bone and Bones - metabolism | Bone Resorption - metabolism | Thiazolidinediones - pharmacology | Bone Marrow - drug effects | Osteoblasts - drug effects | Osteogenesis - drug effects | Drug Resistance - drug effects | Fibroblast Growth Factors - pharmacology | Mice, Knockout | Osteoblasts - pathology | Organ Size - drug effects | Animals | Bone Marrow - pathology | Bone Resorption - pathology | Mice | Osteoprotegerin - metabolism | Osteoblasts - metabolism | Drugs | Fibroblast growth factor | Energy metabolism | Mesenchyme | Diabetes mellitus | Homeostasis | Bone turnover | Hormones | Glucose metabolism | Side effects | Bone mass | Osteoblastogenesis | adipogenesis | Stem cells | rosiglitazone | Lipid metabolism | Peroxisome proliferator-activated receptors | Bone loss | Index Medicus | Biological Sciences
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 07/2011, Volume 26, Issue 7, pp. 1517 - 1532
Journal Article
Biomaterials, ISSN 0142-9612, 2008, Volume 30, Issue 6, pp. 1015 - 1025
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2011, Volume 6, Issue 10, pp. e25900 - e25900
Sclerostin is a product of mature osteocytes embedded in mineralised bone and is a negative regulator of bone mass and osteoblast differentiation. While... 
BONE MORPHOGENETIC PROTEIN | IN-VIVO | BMP ANTAGONIST | BIOLOGY | HUMAN PRIMARY OSTEOBLASTS | RECEPTOR ACTIVATOR | MECHANICAL STIMULATION | PARATHYROID-HORMONE | CELL-DIFFERENTIATION | VAN-BUCHEM-DISEASE | KAPPA-B LIGAND | Osteocytes - drug effects | RANK Ligand - metabolism | Apoptosis - drug effects | Humans | Tartrate-Resistant Acid Phosphatase | Osteoclasts - cytology | Cell Differentiation - genetics | Acid Phosphatase - metabolism | Isoenzymes - metabolism | Adult | Osteoblasts - cytology | Bone Morphogenetic Proteins - pharmacology | Osteogenesis - genetics | Cell Survival - drug effects | Calcification, Physiologic - drug effects | Osteocytes - metabolism | Osteoblasts - drug effects | Osteocytes - cytology | Osteogenesis - drug effects | Cells, Cultured | Genetic Markers | Recombinant Proteins - pharmacology | Osteoclasts - metabolism | Gene Expression Regulation - drug effects | RANK Ligand - genetics | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Mice | Osteoblasts - metabolism | Osteoclasts - drug effects | Bones | RNA | Gene expression | Density | Genes | Homeostasis | Osteocytes | Leukocytes (mononuclear) | SOST protein | Biology | Kinases | Osteoprotegerin | Monoculture | Ethics | Genotype & phenotype | Splenocytes | Peripheral blood mononuclear cells | Tumor necrosis factor-TNF | Biocompatibility | TRANCE protein | Discipline | Recombinant | Cytokines | Caspase | Cultures | Bone mass | Osteoblastogenesis | Low density lipoprotein receptors | Osteoclasts | Acid phosphatase (tartrate-resistant) | Bone | Apoptosis | Index Medicus | Biomedical materials
Journal Article
Nature Medicine, ISSN 1078-8956, 07/2012, Volume 18, Issue 7, pp. 1095 - 1101
Insulin-like growth factor 1 (IGF-1), the most abundant growth factor in the bone matrix, maintains bone mass in adulthood. We now report that IGF-1 released... 
MEDICINE, RESEARCH & EXPERIMENTAL | LIFE-SPAN | PHYSIOLOGY | RESORPTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | OSTEOPOROSIS | CELL BIOLOGY | INSULIN-RECEPTOR | OSTEOBLAST PROGENITORS | RELEVANCE | FRACTURES | POSTMENOPAUSAL WOMEN | GROWTH-FACTOR-I | Bone Matrix - metabolism | Immunohistochemistry | Mesenchymal Stromal Cells - enzymology | Bone and Bones - pathology | Receptor, IGF Type 1 - metabolism | Insulin-Like Growth Factor I - pharmacology | Femur - pathology | TOR Serine-Threonine Kinases - metabolism | Cell Count | Humans | Aging - drug effects | Insulin-Like Growth Factor Binding Protein 3 - pharmacology | Phosphatidylinositol 3-Kinases - metabolism | Femur - diagnostic imaging | Insulin Receptor Substrate Proteins - metabolism | X-Ray Microtomography | Bone and Bones - drug effects | Insulin-Like Growth Factor Binding Protein 3 - metabolism | Bone Matrix - drug effects | Bone and Bones - metabolism | Insulin-Like Growth Factor I - administration & dosage | Bone Resorption - metabolism | Insulin-Like Growth Factor Binding Protein 3 - administration & dosage | Receptor, IGF Type 1 - deficiency | Proto-Oncogene Proteins c-akt - metabolism | Femur - growth & development | Mesenchymal Stromal Cells - drug effects | Bone Resorption - blood | Osteoblasts - enzymology | Osteoblasts - drug effects | Osteogenesis - drug effects | Rats | Enzyme Activation - drug effects | Mice, Knockout | Bone Resorption - diagnostic imaging | Osteoblasts - pathology | Organ Size - drug effects | Animals | Cell Differentiation - drug effects | Bone Resorption - pathology | Mice | Mesenchymal Stromal Cells - pathology | Insulin-Like Growth Factor I - metabolism | Aging - metabolism | Physiological aspects | Research | Insulin-like growth factor 1 | Protein kinases | Stem cells | Bone marrow | Insulin-like growth factors | Index Medicus
Journal Article