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Journal Article
Journal Article
Nature, ISSN 0028-0836, 03/2017, Volume 543, Issue 7645, pp. 385 - 390
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 08/2018, Volume 20, Issue 8, pp. 1817 - 1828
Type 2 diabetes mellitus is now a worldwide health problem with increasing prevalence. Mounting efforts have been made to treat, prevent and predict this... 
lipocalin 2 | osteocalcin | bone | diabetes | energy metabolism | OSTEOCALCIN GAMMA-CARBOXYLATION | FATTY LIVER-DISEASE | RECEPTOR-DEFICIENT MICE | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | MORPHOGENETIC PROTEIN-7 | CIRCULATING SCLEROSTIN LEVELS | ENERGY-METABOLISM | POSTMENOPAUSAL WOMEN | RESORPTION MARKER CTX | Prediabetic State - metabolism | Recombinant Proteins - therapeutic use | RANK Ligand - metabolism | Hypoglycemic Agents - metabolism | Humans | Secretagogues - metabolism | Osteocalcin - genetics | Osteocalcin - pharmacology | Appetite Depressants - therapeutic use | Prediabetic State - drug therapy | Neuropeptide Y - metabolism | RANK Ligand - pharmacology | Osteocalcin - therapeutic use | Bone and Bones - metabolism | Lipocalin-2 - genetics | RANK Ligand - therapeutic use | Lipocalin-2 - therapeutic use | Hypoglycemic Agents - therapeutic use | Osteoclasts - pathology | Appetite Depressants - pharmacology | Neuropeptide Y - therapeutic use | Diabetes Mellitus, Type 2 - prevention & control | Prediabetic State - prevention & control | Appetite Regulation - drug effects | Hypoglycemic Agents - pharmacology | Models, Biological | Diabetes Mellitus, Type 2 - pathology | Secretagogues - pharmacology | Energy Metabolism - drug effects | Bone and Bones - pathology | Neuropeptide Y - genetics | Appetite Depressants - metabolism | Diabetes Mellitus, Type 2 - metabolism | Bone and Bones - drug effects | Secretagogues - therapeutic use | Prediabetic State - pathology | Insulin Secretion - drug effects | Lipocalin-2 - pharmacology | Recombinant Proteins - metabolism | Osteocalcin - metabolism | Osteoblasts - drug effects | Neuropeptide Y - pharmacology | Recombinant Proteins - pharmacology | Osteoclasts - metabolism | RANK Ligand - genetics | Osteoblasts - pathology | Animals | Lipocalin-2 - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Osteoblasts - metabolism | Osteoclasts - drug effects | Prevention | Neuropeptide Y | Glucose metabolism | Medical research | Physiological aspects | Medicine, Experimental | Chronic diseases | Bone morphogenetic proteins | Diabetes | Glucose | Fatty acids | Dextrose | Appetite | Osteocalcin | Adipose tissue | Secretion | Diabetes mellitus | Homeostasis | Energy expenditure | Osteocytes | SOST protein | Hypothalamus | Metabolism | Insulin | Bone resorption | Skeleton | Bone matrix | Diabetes mellitus (non-insulin dependent) | Bone morphogenetic protein 7
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2017, Volume 19, Issue 10, pp. 1274 - 1285
Metastatic cancer is a systemic disease, and metastasis determinants might elicit completely different effects in various target organs. Here we show that... 
CELLS | INVASION | WNT/BETA-CATENIN | PATHWAY | GENES | DICKKOPF-1 | INDUCTION | BETA-CATENIN | CARCINOMA | FAMILY | CELL BIOLOGY | Humans | Lung Neoplasms - metabolism | Transforming Growth Factor beta1 - metabolism | Bone Neoplasms - secondary | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Molecular Targeted Therapy | Neutrophil Infiltration | Bone Neoplasms - metabolism | Breast Neoplasms - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Transfection | Lung Neoplasms - secondary | RNA Interference | Time Factors | Female | Antineoplastic Agents - pharmacology | Bone Neoplasms - genetics | Neuropeptides - genetics | Neutrophils - metabolism | Calcium Signaling | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Latent TGF-beta Binding Proteins - metabolism | Neutrophils - pathology | Lung Neoplasms - genetics | Macrophages - pathology | Mice, Inbred C57BL | Intercellular Signaling Peptides and Proteins - genetics | Neuropeptides - metabolism | Mice, SCID | Breast Neoplasms - drug therapy | Cell Movement - drug effects | Osteoblasts - pathology | Macrophages - metabolism | Animals | Breast Neoplasms - genetics | Wnt Signaling Pathway - drug effects | Lung Neoplasms - prevention & control | Bone Neoplasms - prevention & control | Breast Neoplasms - pathology | Cyclooxygenase 2 - metabolism | Mice, Inbred NOD | Mice, Inbred BALB C | HeLa Cells | Osteoblasts - metabolism | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Wnt protein | Secretion | Lung cancer | Organs | Rac1 protein | JNK protein | Breast cancer | Metastasis | Macrophages | Osteoblasts | Metastases | Recruitment | Calcium signalling | Biomedical materials | Bone cancer | Lungs | Breast | Biocompatibility | Bone | Dkk1 protein | Organotropism | Cancer | Tumors | Ca2+/calmodulin-dependent protein kinase II
Journal Article
Critical Reviews in Eukaryotic Gene Expression, ISSN 1045-4403, 2012, Volume 22, Issue 1, pp. 61 - 86
Journal Article
Kidney International, ISSN 0085-2538, 07/2016, Volume 90, Issue 1, pp. 77 - 89
Bone loss and increased fractures are common complications in chronic kidney disease. Because Wnt pathway activation is essential for normal bone... 
uremia | phosphate | chronic kidney disease | bone | hyperparathyroidism | FGF23 | Rats, Wistar | Decalcification, Pathologic - etiology | Humans | Glucuronidase - metabolism | Male | Uremia - metabolism | Parathyroid Hormone - blood | Renal Insufficiency, Chronic - complications | Wnt Proteins - metabolism | Core Binding Factor Alpha 1 Subunit - metabolism | Tibia - pathology | Renal Insufficiency, Chronic - metabolism | Calcium - blood | Fibroblast Growth Factors - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | beta Catenin - blood | Membrane Proteins - metabolism | Tibia - metabolism | Disease Models, Animal | Biomarkers - metabolism | Osteocalcin - metabolism | Osteoblasts - drug effects | Rats | Phosphorus, Dietary - adverse effects | Fibroblast Growth Factors - pharmacology | Biomarkers - blood | Uremia - complications | Animals | Wnt Signaling Pathway - drug effects | Cathepsin K - metabolism | Calcification, Physiologic | Phosphorus - blood | Phosphorus - metabolism | Cell Line, Tumor | Glucuronidase - pharmacology | Porosity | Osteoblasts - metabolism | Wnt Proteins - antagonists & inhibitors | Decalcification, Pathologic - metabolism | SCLEROSTIN | VASCULAR CALCIFICATION | MINERAL DENSITY | MASS | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | PARATHYROID-HORMONE | RENAL OSTEODYSTROPHY | POSTMENOPAUSAL WOMEN
Journal Article
Journal Article
Nature: international weekly journal of science, ISSN 0028-0836, 01/2014, Volume 506, Issue 7487, pp. 240 - 244
textabstractCells of the osteoblast lineage affect the homing and the number of long-term repopulating haematopoietic stem cells, haematopoietic stem cell... 
PROGENITOR CELLS | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | BONE-MARROW NICHE | NOTCH ACTIVATION | STEM-CELL NICHE | MYELOID-LEUKEMIA | MICE | DIFFERENTIATION | EXPRESSION | MYELODYSPLASTIC SYNDROMES | Osteoblasts - secretion | Receptors, Notch - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Hematopoietic Stem Cells - pathology | Anemia - pathology | Male | Cell Differentiation - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Membrane Proteins - deficiency | Anemia - genetics | Cell Nucleus - metabolism | Tumor Microenvironment - genetics | Cell Transformation, Neoplastic - genetics | Serrate-Jagged Proteins | Base Sequence | Female | Membrane Proteins - metabolism | Intercellular Signaling Peptides and Proteins - deficiency | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Myelodysplastic Syndromes - metabolism | Signal Transduction | Leukemia, Myeloid, Acute - pathology | Membrane Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Calcium-Binding Proteins - deficiency | Hematopoietic Stem Cells - metabolism | Mutation - genetics | beta Catenin - metabolism | beta Catenin - genetics | Anemia - metabolism | Cell Lineage | Osteoblasts - pathology | Animals | Chromosome Aberrations | Myeloid Cells - metabolism | Ligands | Mice | Myelodysplastic Syndromes - genetics | Myeloid Cells - pathology | Cell Transformation, Neoplastic - pathology | Myelodysplastic Syndromes - pathology | Osteoblasts - metabolism | Calcium-Binding Proteins - genetics | Leukemia, Myeloid, Acute - genetics
Journal Article