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Nature medicine, ISSN 1546-170X, 10/2014, Volume 20, Issue 11, pp. 1279 - 1288
The WNT16 locus is a major determinant of cortical bone thickness and nonvertebral fracture risk in humans. The disability, mortality and costs caused by... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Osteocytes - drug effects | Humans | Wnt Proteins - deficiency | RNA, Messenger - metabolism | Wnt Proteins - metabolism | Cell Lineage - drug effects | Fractures, Bone - genetics | Cell Differentiation - genetics | RANK Ligand - pharmacology | Wnt Proteins - genetics | Skull - pathology | Gene Deletion | Organ Size - genetics | Osteogenesis - genetics | Cell Line | Osteoclasts - pathology | Disease Susceptibility | Osteocytes - metabolism | Mice, Inbred C57BL | Osteoblasts - drug effects | Osteogenesis - drug effects | RNA, Messenger - genetics | Cells, Cultured | Signal Transduction - genetics | Osteoclasts - metabolism | Fractures, Bone - metabolism | Aging - pathology | Gene Expression Regulation - drug effects | Osteoblasts - pathology | Organ Size - drug effects | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Osteocytes - pathology | Fractures, Bone - pathology | Osteoprotegerin - metabolism | Osteoblasts - metabolism | Fractures, Bone - prevention & control | Osteoclasts - drug effects | Physiological aspects | Fractures | Research | Wnt proteins | Analysis | Osteoclasts (Biology) | Osteoporosis | Signal transduction | Bones | Glycoproteins | Porosity | Index Medicus | Clinical Medicine | Endokrinologi och diabetes | Klinisk medicin | Endocrinology and Diabetes
Journal Article
Journal of bone and mineral research, ISSN 0884-0431, 09/2012, Volume 27, Issue 9, pp. 1936 - 1950
Like bone mass, bone quality is specified in development, actively maintained postnatally, and disrupted by disease. The roles of osteoblasts, osteoclasts, and... 
MATRIX METALLOPROTEINASE–13 | OSTEOCYTE | REMODELING | FRACTURE RESISTANCE | BONE QUALITY | OSTEOCYTE PERILACUNAR REMODELING | BONE MATRIX | MATRIX METALLOPROTEINASE-13 | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Bone Matrix - metabolism | Lactation | Bone Matrix - diagnostic imaging | Osteocytes - enzymology | X-Ray Microtomography | Tibia - pathology | Matrix Metalloproteinase 13 - deficiency | Fractures, Bone - enzymology | Female | Fractures, Bone - diagnostic imaging | Tibia - physiopathology | Tibia - enzymology | Bone Resorption - physiopathology | Osteoclasts - pathology | Tibia - diagnostic imaging | Organ Size | Osteoclasts - metabolism | Bone Matrix - pathology | Matrix Metalloproteinase 13 - metabolism | Protein Transport | Bone Resorption - diagnostic imaging | Collagen - metabolism | Osteoblasts - pathology | Biomechanical Phenomena | Animals | Calcification, Physiologic | Bone Resorption - pathology | Fractures, Bone - physiopathology | Osteocytes - pathology | Fractures, Bone - pathology | Mice | Osteoblasts - metabolism | Bone Remodeling | Osteogenesis | Biological products | Fractures | Phosphatases | Collagen | Analysis | Stem cells | Bones | Health aspects | Density | Index Medicus | Bone remodelling | Mechanical properties | Osteocytes | SOST protein | Matrix metalloproteinase | Collagenase 3 | Osteoblasts | Diaphysis | Bone histomorphometry | Bone mass | Molecular modelling | Cross-linking | Extracellular matrix | Osteoclasts | Acid phosphatase (tartrate-resistant) | Bone loss | Bone matrix | matrix metalloproteinase-13 | remodeling | fracture resistance | bone matrix | osteocyte | bone quality | osteocyte perilacunar remodeling
Journal Article
Journal of bone and mineral research, ISSN 0884-0431, 08/2012, Volume 27, Issue 8, pp. 1757 - 1772
Chronic kidney disease–mineral bone disorder (CKD‐MBD) is defined by abnormalities in mineral and hormone metabolism, bone histomorphometric changes, and/or... 
RENAL OSTEODYSTROPHY | OSTEOCYTE | WNT/β‐CATENIN | WNT/β-CATENIN | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Bone and Bones - pathology | Chronic Kidney Disease-Mineral and Bone Disorder - pathology | Chronic Kidney Disease-Mineral and Bone Disorder - blood | Humans | Middle Aged | Chronic Kidney Disease-Mineral and Bone Disorder - physiopathology | Glycoproteins - metabolism | Cardiovascular Abnormalities - blood | Male | Chronic Kidney Disease-Mineral and Bone Disorder - metabolism | Gene Expression Profiling | Cardiovascular Abnormalities - pathology | Cardiovascular Abnormalities - physiopathology | Kidney Failure, Chronic - pathology | Bone and Bones - metabolism | Female | Kidney Failure, Chronic - physiopathology | Osteoclasts - pathology | Cardiovascular Abnormalities - complications | Osteocytes - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Mutation - genetics | Osteoclasts - metabolism | Disease Progression | Animals | Kidney Failure, Chronic - blood | Wnt Signaling Pathway - genetics | Biopsy | Calcification, Physiologic | Kidney Failure, Chronic - complications | Osteocytes - pathology | Mice | Bone Remodeling | NIMA-Related Kinases | Vascular Calcification | Index Medicus | Calcification (ectopic) | Renal function | Renal osteodystrophy | Wnt protein | Polycystic kidney | catenin | Osteocytes | Bone diseases | Minerals | Gene expression | Osteoprotegerin | Gene silencing | Signal transduction | NF- Kappa B protein | Osteoclasts | Kidney diseases | TRANCE protein | Age | Osteogenesis
Journal Article