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Biochemical and biophysical research communications, ISSN 0006-291X, 09/2017, Volume 490, Issue 4, pp. 1274 - 1281
Enhanced turnover of subchondral trabecular bone is a hallmark of rheumatoid arthritis (RA) and it results from an imbalance between bone resorption and bone... 
Autoimmunity | Phosphotransferases (Alcohol Group Acceptor) - immunology | Temporomandibular Joint - pathology | rac1 GTP-Binding Protein - immunology | Mice, Inbred MRL lpr | Arthritis, Rheumatoid - drug therapy | Bone Resorption - genetics | Bone Marrow Cells - immunology | fas Receptor - genetics | Cell Differentiation | Mitogen-Activated Protein Kinases - immunology | Disease Models, Animal | NF-kappa B - antagonists & inhibitors | Osteoclasts - pathology | Macrophages - pathology | Signal Transduction | Bone Marrow Cells - pathology | Bone Resorption - immunology | Temporomandibular Joint - drug effects | Arthritis, Rheumatoid - genetics | Sphingosine - analogs & derivatives | Proto-Oncogene Proteins c-akt - immunology | Bone Resorption - pathology | Temporomandibular Joint - immunology | Mitogen-Activated Protein Kinases - genetics | Mice | Neuropeptides - immunology | NF-kappa B - immunology | Osteogenesis - immunology | Lysophospholipids - immunology | Proto-Oncogene Proteins c-akt - genetics | RANK Ligand - immunology | fas Receptor - immunology | Osteoclasts - immunology | Receptors, Lysosphingolipid - genetics | Bone Marrow Cells - drug effects | Female | Neuropeptides - genetics | Macrophages - immunology | Osteogenesis - drug effects | Gene Expression Regulation | Phosphotransferases (Alcohol Group Acceptor) - genetics | Sphingosine - immunology | Arthritis, Rheumatoid - pathology | Peptides - pharmacology | Bone Resorption - prevention & control | RANK Ligand - genetics | Receptors, Lysosphingolipid - immunology | Animals | NF-kappa B - genetics | Macrophages - drug effects | Primary Cell Culture | Arthritis, Rheumatoid - immunology | Osteoclasts - drug effects | rac1 GTP-Binding Protein - genetics
Journal Article
Nature Reviews Rheumatology, ISSN 1759-4790, 02/2015, Volume 11, Issue 2, pp. 74 - 76
Even though activation of immunity is associated with bone destruction, new mechanisms have been described in 2014 through which immunology-associated pathways... 
IMMUNE | RHEUMATOLOGY | Bone Remodeling - immunology | Animals | Humans | Bone Resorption - immunology | Scleroderma, Systemic - immunology | Neovascularization, Physiologic - immunology | Osteogenesis - immunology | T-Lymphocytes, Regulatory - immunology
Journal Article
by Chao, YH and Wu, HP and Wu, KH and Tsai, YG and Peng, CT and Lin, KC and Chao, WR and Lee, MS and Fu, YC
PLOS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, p. e110338
Sepsis remains an important cause of death worldwide, and vigorous immune responses during sepsis could be beneficial for bacterial clearance but at the price... 
SURVIVAL | COTRANSPLANTATION | BACTERIAL CLEARANCE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | MECHANISMS | GENERATION | STROMAL CELLS | IMMUNOMODULATION | TRANSPLANTATION | REDUCE | Antigens, CD - immunology | Rats, Wistar | Coculture Techniques | Humans | Adipocytes - cytology | Male | Antigens, CD - genetics | T-Lymphocytes, Regulatory - pathology | Mesenchymal Stromal Cells - immunology | T-Lymphocytes, Regulatory - immunology | Mesenchymal Stromal Cells - cytology | Sepsis - pathology | Bone Marrow Cells - immunology | Tumor Necrosis Factor-alpha - immunology | Cell Differentiation | Osteoblasts - cytology | Adipocytes - immunology | Disease Models, Animal | Fetal Blood - immunology | Gene Expression | Sepsis - immunology | Bone Marrow Cells - cytology | Immunomodulation | Tumor Necrosis Factor-alpha - secretion | Osteoblasts - immunology | Rats | Fetal Blood - cytology | Interleukin-6 - secretion | Sepsis - genetics | Animals | Sepsis - therapy | Interleukin-6 - immunology | Lymphocyte Count | Mesenchymal Stem Cell Transplantation | Infection | Inflammation | Cytokines | T cells | Comparative analysis | Stem cells | Health sciences | Pediatrics | Transplants & implants | Mesenchyme | Interleukin | Immune clearance | Leukocytes (mononuclear) | Lymphocytes T | Interleukin 6 | Biomedical materials | Lymphocytes | Animal tissues | Bone marrow | Peripheral blood mononuclear cells | CD25 antigen | Biocompatibility | Immune system | Adipogenesis | Immune response | Immunoregulation | Cecum | CD3 antigen | Tumor necrosis factor-α | CD4 antigen | Medicine | Serum levels | Immunosuppression | Hospitals | Antibiotics | Blood circulation | Skin & tissue grafts | Sepsis | Umbilical cord | Surface markers | Osteogenesis
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 05/2016, Volume 310, Issue 9, pp. E762 - E773
ApoE-null (ApoE-KO) mice fed a high-fat diet (HFD) develop atherosclerosis, due in part to activation of vascular inflammation by oxidized low-density... 
Osteoporosis | Osteoclasts | Wnt signaling | Inflammation | Bone remodeling | Osteoblasts | Atherosclerosis - genetics | Cell Count | Tumor Necrosis Factor-alpha - genetics | Wnt Signaling Pathway - immunology | Bone Diseases, Metabolic - pathology | Monocytes - immunology | Femur - diagnostic imaging | Interleukin-1beta - genetics | Osteoclasts - cytology | Wnt Proteins - metabolism | X-Ray Microtomography | Cancellous Bone - immunology | Cancellous Bone - diagnostic imaging | Immunomagnetic Separation | Bone and Bones - metabolism | Diet, High-Fat | Tumor Necrosis Factor-alpha - immunology | Spine - immunology | Lipoproteins, LDL - metabolism | Atherosclerosis - pathology | Atherosclerosis - immunology | Interleukin-6 - genetics | Femur - metabolism | Femur - immunology | Reverse Transcriptase Polymerase Chain Reaction | Absorptiometry, Photon | Blotting, Western | Mice, Knockout | Aorta - pathology | Wnt Proteins - immunology | Cortical Bone - drug effects | Interleukin-6 - immunology | Mice | Bone Diseases, Metabolic - genetics | Bone and Bones - pathology | Femur - pathology | Cancellous Bone - metabolism | Spine - metabolism | Cortical Bone - pathology | Flow Cytometry | Wnt Proteins - genetics | Cortical Bone - immunology | Bone and Bones - diagnostic imaging | Cancellous Bone - pathology | Female | Osteoblasts - cytology | Spine - pathology | Macrophages - immunology | Arachidonate 12-Lipoxygenase - genetics | Bone Density | Bone Diseases, Metabolic - diagnostic imaging | Bone Diseases, Metabolic - immunology | Interleukin-1beta - immunology | Cortical Bone - metabolism | Spine - diagnostic imaging | Animals | Arachidonate 15-Lipoxygenase - genetics | Wnt Signaling Pathway - genetics | Apolipoproteins E - genetics | Bone and Bones - immunology | Porosity | Osteogenesis | Medical research | Atherosclerosis | Physiological aspects | Medicine, Experimental | Skeleton | Research | Wnt proteins | Health aspects | inflammation | osteoclasts | bone remodeling | osteoblasts | osteoporosis
Journal Article
Immunological Reviews, ISSN 0105-2896, 01/2010, Volume 233, Issue 1, pp. 301 - 312
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2016, Volume 11, Issue 6, p. e0156708
Severe Staphylococcus aureus (S. aureus) infections pose an immense threat to population health and constitute a great burden for the health care worldwide.... 
RHEUMATOID-ARTHRITIS | OSTEOMYELITIS | ACTIVATION | CYTOKINES | PORPHYROMONAS-GINGIVALIS | MULTIDISCIPLINARY SCIENCES | SEPTIC ARTHRITIS | DIFFERENTIATION | INDUCTION | NF-KAPPA-B | EXPRESSION | Toll-Like Receptor 2 - genetics | Staphylococcal Infections - pathology | RNA, Messenger - metabolism | Osteogenesis - immunology | Bone Resorption - microbiology | RANK Ligand - immunology | Toll-Like Receptor 2 - deficiency | Osteoclasts - immunology | Gene Expression Regulation, Developmental | Bone Marrow Cells - immunology | Osteoprotegerin - genetics | Staphylococcal Infections - microbiology | Macrophages - immunology | Macrophages - microbiology | Osteoclasts - microbiology | Osteogenesis - genetics | Animals, Newborn | Signal Transduction | Staphylococcal Infections - immunology | Mice, Inbred C57BL | RNA, Messenger - genetics | Osteoblasts - immunology | Osteoprotegerin - immunology | Prostaglandins - biosynthesis | Bone Resorption - immunology | Staphylococcus aureus - pathogenicity | Mice, Knockout | RANK Ligand - genetics | Animals | Parietal Bone - microbiology | Parietal Bone - immunology | Bone Resorption - pathology | Bone Marrow Cells - microbiology | Toll-Like Receptor 2 - immunology | Staphylococcus aureus - immunology | Mice | Osteoblasts - microbiology | Primary Cell Culture | Parietal Bone - growth & development | Health care | Neonates | Prostheses | Destruction | Stimulation | Arthritis | Macrophages | Osteoblasts | Osteoprotegerin | Proteins | Bone resorption | Bone (parietal) | Osteoporosis | Receptors | Microorganisms | Biomedical materials | Prostaglandins | Bone growth | Toll-like receptors | Bone marrow | Biocompatibility | Bone loss | TRANCE protein | Immune system | NF-κB protein | Bacterial infections | Cytokines | Internal medicine | Health risks | Staphylococcus infections | Gene expression | Joint diseases | Morbidity | Medicine | Osteoclastogenesis | Signaling | TLR2 protein | Rheumatoid arthritis | Ligands | Osteoclasts | Parietal bone | Apoptosis | Clinical Medicine | Odontologi | Dentistry | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 09/2016, Volume 39, Issue 4, pp. 1347 - 1359
Background/Aims: Osteomyelitis is defined as an inflammation of the bones and bone marrow. The inflammatory microenvironment attenuates the osteogenic... 
Original Paper | Human bone mesenchymal stem cells | lncRNA microarray | SpA | Osteogenic differentiation | NONHSAT009968 | PHYSIOLOGY | OSTEOBLAST DIFFERENTIATION | INFLAMMATORY RESPONSES | CELL BIOLOGY | SIGNALING PATHWAY | GROWTH | UP-REGULATION | EXPRESSION | Mesenchymal Stem Cells - immunology | Osteopontin - genetics | RNA, Small Interfering - genetics | Interleukin-1alpha - immunology | Lentivirus - immunology | Oligonucleotide Array Sequence Analysis | Humans | Tumor Necrosis Factor-alpha - genetics | Bone and Bones - drug effects | RNA, Long Noncoding - immunology | Collagen Type I - genetics | RNA, Small Interfering - immunology | Mesenchymal Stem Cells - cytology | Mesenchymal Stem Cells - drug effects | Tumor Necrosis Factor-alpha - immunology | Lentivirus - genetics | Cell Differentiation | Interleukin-1alpha - genetics | Osteoblasts - cytology | Alkaline Phosphatase - immunology | Osteogenesis - genetics | Bone and Bones - cytology | Staphylococcal Protein A - pharmacology | Alkaline Phosphatase - genetics | Genetic Vectors - chemistry | Interleukin-6 - genetics | Signal Transduction | Osteoblasts - drug effects | Osteogenesis - drug effects | Cells, Cultured | Gene Expression Regulation | Osteoblasts - immunology | Core Binding Factor Alpha 1 Subunit - immunology | Genetic Vectors - metabolism | Inflammation | RNA, Long Noncoding - genetics | Collagen Type I - immunology | Osteopontin - immunology | Interleukin-6 - immunology | Bone and Bones - immunology | RNA, Long Noncoding - antagonists & inhibitors | Core Binding Factor Alpha 1 Subunit - genetics
Journal Article