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osteogenic protein-1 (282) 282
animals (267) 267
humans (224) 224
index medicus (161) 161
bone morphogenetic protein 7 (158) 158
bone morphogenetic proteins (158) 158
orthopedics (140) 140
male (103) 103
human osteogenic protein-1 (89) 89
differentiation (85) 85
bone morphogenetic proteins - pharmacology (84) 84
bone morphogenetic protein (79) 79
rats (78) 78
surgery (78) 78
cell biology (71) 71
expression (71) 71
female (70) 70
in-vitro (69) 69
op-1 (61) 61
bone morphogenetic protein-7 (55) 55
transforming growth factor beta (52) 52
bone morphogenetic proteins - therapeutic use (51) 51
cells, cultured (51) 51
regeneration (51) 51
transforming growth factor beta - pharmacology (51) 51
bmp-7 (49) 49
mice (49) 49
middle aged (47) 47
engineering, biomedical (46) 46
endocrinology & metabolism (45) 45
tissue engineering (45) 45
aged (44) 44
biochemistry & molecular biology (44) 44
collagen (43) 43
adult (42) 42
growth-factor-beta (42) 42
cartilage (41) 41
analysis (40) 40
proteins (40) 40
bone morphogenetic proteins - administration & dosage (39) 39
defects (39) 39
growth factors (39) 39
human articular chondrocytes (39) 39
bone morphogenetic protein-2 (37) 37
materials science, biomaterials (37) 37
rats, sprague-dawley (36) 36
bone morphogenetic proteins - metabolism (35) 35
radiography (35) 35
bone morphogenetic protein 2 (34) 34
cells (34) 34
dentistry, oral surgery & medicine (34) 34
mesenchymal stem-cells (34) 34
osteogenesis - drug effects (34) 34
disease models, animal (32) 32
growth (32) 32
repair (32) 32
osteoarthritis (31) 31
rabbits (31) 31
fracture healing - drug effects (30) 30
gene expression (30) 30
immunohistochemistry (30) 30
recombinant proteins - pharmacology (30) 30
bmp (29) 29
bone morphogenetic proteins - physiology (29) 29
cell differentiation - drug effects (29) 29
in-vivo (29) 29
bone morphogenetic proteins - genetics (28) 28
gene-expression (28) 28
stem cells (28) 28
bone regeneration (27) 27
clinical neurology (27) 27
fractures (27) 27
bone morphogenetic protein 7 - pharmacology (26) 26
bone transplantation (26) 26
chondrocytes - metabolism (26) 26
extracellular-matrix (26) 26
tgf-beta (26) 26
bone (25) 25
dentistry (25) 25
fracture healing (25) 25
model (25) 25
osteogenesis (25) 25
proliferation (25) 25
time factors (25) 25
treatment outcome (25) 25
alkaline phosphatase - metabolism (24) 24
bone regeneration - drug effects (24) 24
medicine & public health (24) 24
stem-cells (24) 24
cartilage, articular - metabolism (23) 23
factor-beta superfamily (23) 23
messenger-rna (23) 23
osteogenesis - physiology (23) 23
biomedical materials (22) 22
osteogenic protein (22) 22
rheumatology (22) 22
transplantation, autologous (22) 22
bone morphogenetic protein 7 - therapeutic use (21) 21
bone transplantation - methods (21) 21
dose-response relationship, drug (21) 21
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Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 2002, Volume 1588, Issue 2, pp. 126 - 134
Journal Article
Journal Article
HSS Journal, ISSN 1556-3316, 2/2013, Volume 9, Issue 1, pp. 90 - 95
Proximal tibiofibular joint (PTFJ) instability is rare, but when encountered can be difficult to manage. Previously reported forms of treatment, including cast... 
OP-1 | knee | Surgical Orthopedics | Medicine & Public Health | Sports Medicine | osteogenic protein-1 | Orthopedics | Rheumatology | Anesthesiology | Imaging / Radiology | PTFJ | proximal tibiofibular joint | Case Report
Journal Article
Journal of Clinical and Diagnostic Research, ISSN 2249-782X, 08/2013, Volume 7, Issue 8, pp. 1565 - 1567
Age and oxidative stress have been implicated as the main causes of the cartilage damage in osteoarthritis (OA). The osteogenic protein-1(OP-1), a member of... 
Antioxidants | Osteogenic protein-1 | Cartilage metabolic markers | Original
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 2002, Volume 87, Issue 3, pp. 292 - 304
The effects of Osteogenic Protein‐1 (OP‐1, BMP‐7) on the differentiation of the pluripotent mesenchymal cell line, C2C12, were examined. OP‐1 at 50 ng/ml... 
BMP receptor expression | osteogenic protein‐1 | C2C12 | bone morphogenetic protein‐7 | osteoblastic cell differentiation | gene expression | BMP expression | Osteogenic protein-1 | Osteoblastic cell differentiation | Bone morphogenetic protein-7 | Gene expression | SIGNALING PATHWAYS | BONE MORPHOGENETIC PROTEIN-2 | MESSENGER-RNA EXPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRIMARY CULTURES | CELL BIOLOGY | I RECEPTORS | bone morphogenetic protein-7 | osteogenic protein-1 | GENE-EXPRESSION | EXTRACELLULAR-MATRIX | FACTOR-BETA SUPERFAMILY | TERMINAL DIFFERENTIATION | GROWTH-FACTOR BETA-1 | Gene Expression - drug effects | Integrin-Binding Sialoprotein | Microscopy, Phase-Contrast | Humans | Alkaline Phosphatase - metabolism | Mesoderm - drug effects | Mesoderm - cytology | Muscle Fibers, Skeletal - drug effects | Proto-Oncogene Proteins - biosynthesis | RNA, Messenger - biosynthesis | Sialoglycoproteins - biosynthesis | Core Binding Factor Alpha 2 Subunit | Bone Morphogenetic Proteins - biosynthesis | Osteoblasts - cytology | Bone Morphogenetic Proteins - genetics | Bone Morphogenetic Proteins - pharmacology | Transforming Growth Factor beta | Cell Line | Osteocalcin - biosynthesis | Neoplasm Proteins - biosynthesis | Osteoblasts - drug effects | Transcription Factors - biosynthesis | Recombinant Proteins - genetics | Recombinant Proteins - pharmacology | Collagen Type I - biosynthesis | Animals | Cell Differentiation - drug effects | Receptors, Growth Factor - biosynthesis | Bone Morphogenetic Protein Receptors | Mice | Osteoblasts - metabolism | DNA-Binding Proteins - biosynthesis | Bone Morphogenetic Protein 7
Journal Article
International Journal of Spine Surgery, ISSN 2211-4599, 2016, Volume 10, Issue 2016, p. 33
A narrative review of literature. This manuscript intends to provide a review of clinically relevant bone substitutes and bone expanders for spinal surgery in... 
I-factor | Spine fusion | Allografts | Autologous growth factors | Îtricalcium phosphate (ß-tcp) | Demineralized bone matrix (dbm) | Hydroxyapatite | Synthetic peptides | Ceramics | Rhbmp-2 | Bone substitutes | Osteogenic protein-1 (op-1)
Journal Article
Food Chemistry, ISSN 0308-8146, 2009, Volume 116, Issue 4, pp. 990 - 994
Journal Article
Journal Article
Journal Article
Journal Article
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, ISSN 1617-7959, 08/2008, Volume 7, Issue 4, pp. 263 - 276
Cartilage growth may involve alterations in the balance between the swelling tendency of proteoglycans and the restraining function of the collagen network.... 
LONG-TERM CULTURE | FACTOR-BETA | PROTEOGLYCAN SYNTHESIS | BIOPHYSICS | BOVINE ARTICULAR-CARTILAGE | ENGINEERING, BIOMEDICAL | AGE-RELATED-CHANGES | FEMORAL-HEAD CARTILAGE | TENSILE PROPERTIES | OSTEOGENIC PROTEIN-1 OP-1 | MANDIBULAR CONDYLAR CARTILAGE | MECHANICAL-PROPERTIES | Cartilage | Networks | Proteoglycans | Collagens | Mathematical models | Serums | Metabolism | Integrity
Journal Article
Biochemical Journal, ISSN 0264-6021, 04/2006, Volume 395, Issue 1, pp. 1 - 19
The six members of the insulin-like growth factor-binding protein family (IGFBP-1-6) are important components of the IGF (insulin-like growth factor) axis. In... 
Insulin-like growth factor-I (IGF-I) | Extracellular matrix (ECM) | Insulin-like growth factor-binding protein 5 (IGFBP-5) | Glycosaminoglycan | Mammary gland | Proteolysis | insulin-like growth factor-binding protein 5 (IGFBP-5) | BIOCHEMISTRY & MOLECULAR BIOLOGY | FACTOR (IGF)-BINDING PROTEIN-5 | ADULT-RAT SERUM | LOW-MOLECULAR-WEIGHT | FACTOR BINDING-PROTEIN-5 GENE | BREAST-CANCER CELLS | extracellular matrix (ECM) | insulin-like growth factor-I (IGF-I) | SMOOTH-MUSCLE-CELLS | mammary gland | ACID-LABILE SUBUNIT | glycosaminoglycan | FACTOR-I RECEPTOR | proteolysis | C-TERMINAL FRAGMENTS | MAMMARY EPITHELIAL-CELLS | Neoplasms - metabolism | Insulin-Like Growth Factor Binding Protein 5 - chemistry | Animals | Extracellular Matrix - metabolism | Protein Binding | Insulin-Like Growth Factor Binding Protein 5 - metabolism | Protein Processing, Post-Translational | Insulin-Like Growth Factor Binding Protein 5 - genetics | Somatomedins - metabolism | IGF-IIR, IGF-II receptor | ECM, extracellular matrix | PGE2, prostaglandin E2 | RT, reverse transcription | Review | IRS, IR substrate | OE2, oestradiol | tPA, tissue plasminogen activator | PAI-1, plasminogen activator inhibitor-1 | TSP-1, thrombospondin-1 | ERK1 | pSMC, porcine smooth-muscle cell | IGFBP, IGF-binding protein | NBP-4, N-terminus of IGFBP-4 (residues 3–82) | OP-1, osteogenic protein-1 | IGF, insulin-like growth factor | RA, retinoic acid | enhancer-binding protein | IR, insulin receptor | FHL-2, four-and-a-half LIM domain 2 | VN, vitronectin | 2, extracellular-signal-regulated protein kinase 1 | EBP, CCAAT | OPN, osteopontin | GAG, glycosaminoglycan | GH, growth hormone | RASSF1C, isoform C of the Ras association family 1 protein group | ADAM, adisintegrin and metalloprotease | ER, oestrogen receptor | AP-2, activator protein 2 | IGF-IR, IGF-I receptor | CAT, chloramphenicol acetyltransferase | CBP-4, C-terminus of insulin-like growth factor-binding protein 4 (residues 151–232) | SPR, surface plasmon resonance | MAPK, mitogen-activated protein kinase | PAPP, pregnancy-associated plasma protease
Journal Article