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Cancer Research, ISSN 0008-5472, 05/2010, Volume 70, Issue 9, pp. 3494 - 3504
The tropism of breast cancer cells for bone and their tendency to induce an osteolytic phenotype are a result of interactions between breast cancer cells and... 
LYSYL OXIDASE | LUNG-CANCER | TGF-BETA | COLLAGENASE-3 MMP-13 | METASTASIS | HORMONE-RELATED PROTEIN | ONCOLOGY | GENE-EXPRESSION | MATRIX-METALLOPROTEINASE-9 | HUMAN BREAST-CANCER | SQUAMOUS-CELL CARCINOMAS | Bone and Bones - pathology | Up-Regulation | Adenocarcinoma - pathology | Osteoprotegerin - biosynthesis | Bone Neoplasms - secondary | Gene Expression Profiling | Mammary Neoplasms, Experimental - metabolism | Matrix Metalloproteinase 13 - biosynthesis | Bone Neoplasms - metabolism | RNA, Messenger - biosynthesis | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 9 - genetics | Bone and Bones - metabolism | Mammary Neoplasms, Experimental - pathology | Female | Mammary Neoplasms, Experimental - enzymology | Osteolysis - pathology | Matrix Metalloproteinase 9 - biosynthesis | Osteoclasts - pathology | Bone Neoplasms - enzymology | Signal Transduction | Osteolysis - genetics | Matrix Metalloproteinase 13 - genetics | RNA, Messenger - genetics | Adenocarcinoma - enzymology | Bone and Bones - enzymology | RANK Ligand - biosynthesis | Osteolysis - metabolism | Matrix Metalloproteinase 13 - metabolism | Animals | Osteolysis - enzymology | Cell Line, Tumor | Matrix Metalloproteinase Inhibitors | Mice | Mice, Inbred BALB C | Osteoclasts - enzymology | Enzyme Activation | Transforming Growth Factor beta - metabolism | Index Medicus
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2014, Volume 443, Issue 3, pp. 944 - 949
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 03/2018, Volume 233, Issue 3, pp. 2398 - 2408
Inactivation of GSK‐3β enhances bone mass through both increased osteoblast differentiation and suppressed osteoclastogenesis in an animal model for mechanical... 
bone implant | mechanical instability | Wnt signaling | GSK‐3β | osteolysis | GSK-3β | CELLS | ACTIVATION | PHYSIOLOGY | RESORPTION | BONE MORPHOGENETIC PROTEIN-2 | WNT16 | RAT MODEL | CELL BIOLOGY | IN-VIVO | FRACTURES | FLUID PRESSURE | GSK-3 beta | EXPRESSION | RANK Ligand - metabolism | Tartrate-Resistant Acid Phosphatase - blood | Alkaline Phosphatase - metabolism | Male | RNA, Messenger - metabolism | Core Binding Factor Alpha 1 Subunit - metabolism | Bone Plates | Tibia - pathology | Collagen Type I - genetics | Prosthesis Failure | Time Factors | Osteolysis - prevention & control | Osteolysis - pathology | Disease Models, Animal | Bone Morphogenetic Protein 2 - genetics | Tibia - enzymology | Osteoclasts - pathology | Alkaline Phosphatase - genetics | Prosthesis Implantation - instrumentation | Rats, Sprague-Dawley | beta Catenin - metabolism | Osteolysis - enzymology | Osteoprotegerin - metabolism | Bone Morphogenetic Protein 2 - metabolism | Osteoprotegerin - genetics | Collagen Type I - metabolism | Osteoblasts - enzymology | Osteolysis - genetics | Osteoblasts - drug effects | Osteogenesis - drug effects | RNA, Messenger - genetics | Gene Expression Regulation | Glycogen Synthase Kinase 3 beta - antagonists & inhibitors | Transcription Factors - genetics | Tibia - drug effects | Glycogen Synthase Kinase 3 beta - metabolism | Tibia - surgery | beta Catenin - genetics | RANK Ligand - genetics | Transcription Factors - metabolism | Osteoblasts - pathology | Animals | Wnt Signaling Pathway - drug effects | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Osteoclasts - enzymology | Protein Kinase Inhibitors - pharmacology | Core Binding Factor Alpha 1 Subunit - genetics | Osteoclasts - drug effects | Mechanical instability | Osteolysis | Bone implant | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | bone implant; GSK-3 beta; mechanical instability; osteolysis; Wnt signaling | Farmakologi och toxikologi | Pharmacology and Toxicology
Journal Article
Human Pathology, ISSN 0046-8177, 2010, Volume 41, Issue 9, pp. 1320 - 1329
Journal Article
Science Translational Medicine, ISSN 1946-6234, 08/2016, Volume 8, Issue 353, pp. 353ra113 - 353ra113
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 12/2007, Volume 22, Issue 12, pp. 1933 - 1942
Journal Article
Cancer Investigation, ISSN 0735-7907, 2009, Volume 27, Issue 4, pp. 435 - 442
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2013, Volume 288, Issue 47, pp. 33634 - 33641
Phospholipase C γ2 (PLCγ2) is a critical regulator of innate immune cells and osteoclasts (OCs) during inflammatory arthritis. Both the catalytic domain and... 
Inflammation - chemically induced | Inflammation - pathology | RANK Ligand - metabolism | Bone Marrow Cells - enzymology | I-kappa B Proteins - metabolism | Phosphoproteins - metabolism | I-kappa B Proteins - genetics | Osteolysis - drug therapy | Phosphorylation - genetics | Inflammation - drug therapy | Phospholipase C gamma - genetics | Phosphorylation - drug effects | Receptor Activator of Nuclear Factor-kappa B - metabolism | Osteolysis - pathology | NF-KappaB Inhibitor alpha | Osteoclasts - pathology | Phospholipase C gamma - metabolism | Lipopolysaccharides - toxicity | Osteolysis - genetics | Proto-Oncogene Proteins c-jun - genetics | NFATC Transcription Factors - metabolism | Bone Marrow Cells - pathology | Proto-Oncogene Proteins c-fos - metabolism | Signal Transduction - genetics | Phosphoproteins - genetics | src Homology Domains | RANK Ligand - genetics | Animals | Signal Transduction - drug effects | Osteolysis - enzymology | Proto-Oncogene Proteins c-jun - metabolism | Receptor Activator of Nuclear Factor-kappa B - genetics | Inflammation - genetics | Proto-Oncogene Proteins c-fos - genetics | Mice | Osteoclasts - enzymology | Phospholipase C gamma - antagonists & inhibitors | Inflammation - enzymology | NFATC Transcription Factors - genetics | Signaling | Signal Transduction | Bone Erosion | Cell Differentiation | Osteoclast | RANK | Bone | Gab2 | Osteolysis | Phospholipase C | PLC gamma 2
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2003, Volume 100, Issue 12, pp. 7247 - 7252
Journal Article
Journal Article