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European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 10/2018, Volume 45, Issue 11, pp. 1873 - 1883
Journal Article
British Journal of Haematology, ISSN 0007-1048, 11/2014, Volume 167, Issue 3, pp. 366 - 375
Summary Dickkopf‐1 (DKK1), expressed by myeloma cells, suppresses osteoblast function and plays a key role in bone disease in multiple myeloma. BHQ880, a human... 
BHQ880 | multiple myeloma | Phase I | skeletal‐related event | Multiple myeloma | Skeletal-related event | BONE-DISEASE | DICKKOPF-1 | skeletal-related event | DKK1 | IN-VITRO | SERUM CONCENTRATIONS | OSTEOBLASTS | GROWTH | DOUBLE-BLIND | RECEPTOR-RELATED PROTEIN-5 | STEM-CELL TRANSPLANTATION | HEMATOLOGY | Recurrence | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Imidazoles - administration & dosage | Antibodies, Monoclonal - therapeutic use | Male | Neoplasm Proteins - antagonists & inhibitors | Osteolysis - etiology | Molecular Targeted Therapy | Osteolysis - drug therapy | Multiple Myeloma - drug therapy | Hypertension - chemically induced | Diphosphonates - therapeutic use | Female | Imidazoles - therapeutic use | Drug Therapy, Combination | Diphosphonates - adverse effects | Anabolic Agents - therapeutic use | Bone Density Conservation Agents - adverse effects | Multiple Myeloma - complications | Imidazoles - adverse effects | Anabolic Agents - adverse effects | Bone Resorption - drug therapy | Antibodies, Monoclonal - pharmacokinetics | Bone Density Conservation Agents - therapeutic use | Fractures, Spontaneous - etiology | Diphosphonates - administration & dosage | Spinal Cord Compression - etiology | Bone Density Conservation Agents - administration & dosage | Bone Resorption - prevention & control | Maximum Tolerated Dose | Osteolysis - blood | Anabolic Agents - administration & dosage | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Anabolic Agents - pharmacokinetics | Intercellular Signaling Peptides and Proteins - immunology | Medical research | Care and treatment | Relapse | Immunoglobulin G | Medicine, Experimental | Bones | Density | Diseases | Index Medicus
Journal Article
Small, ISSN 1613-6810, 05/2015, Volume 11, Issue 17, pp. 2080 - 2086
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 02/2013, Volume 28, Issue 2, pp. 333 - 340
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2016, Volume 113, Issue 32, pp. E4601 - E4609
Journal Article
British Journal of Haematology, ISSN 0007-1048, 07/2017, Volume 178, Issue 1, pp. 61 - 71
Journal Article
Journal Article
Strahlentherapie und Onkologie, ISSN 0179-7158, 2/2011, Volume 187, Issue 2, pp. 140 - 143
Journal Article