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Journal of molecular and cellular cardiology, ISSN 0022-2828, 2016, Volume 91, pp. 228 - 237
Journal Article
Digestive and Liver Disease, ISSN 1590-8658, 2015, Volume 48, Issue 3, pp. 223 - 230
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 10/2017, Volume 12, Issue 10, p. e0186444
.... Our previous studies revealed that the novel neuropeptide Pth4, synthesized by hypothalamic cells, was involved in bone metabolism via phosphate regulation in adult zebrafish... 
PATHWAYS | OSTEOBLAST DIFFERENTIATION | METABOLISM | PHOSPHATE HOMEOSTASIS | BONE-FORMATION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | PARATHYROID-HORMONE | MODEL | FGF23 | PHEX | Calcinosis - genetics | Bone and Bones - pathology | Neurons - pathology | Hypothalamus - growth & development | Xenopus Proteins - genetics | Laser Therapy | Pyrophosphatases - genetics | Green Fluorescent Proteins - genetics | Osteonectin - genetics | Gene Expression Regulation, Developmental | Bone and Bones - metabolism | PHEX Phosphate Regulating Neutral Endopeptidase - genetics | Neurons - metabolism | Genes, Reporter | Osteogenesis - genetics | Calcification, Physiologic - genetics | Green Fluorescent Proteins - metabolism | PHEX Phosphate Regulating Neutral Endopeptidase - metabolism | Bone Density | Signal Transduction | Animals, Genetically Modified | Zebrafish Proteins - metabolism | Parathyroid Hormone-Related Protein - genetics | Osteonectin - metabolism | Zebrafish | Transcription Factors - genetics | Parathyroid Hormone-Related Protein - metabolism | Pyrophosphatases - metabolism | Transcription Factors - metabolism | Osteoblasts - pathology | Hypothalamus - injuries | Phosphates - metabolism | Animals | Hypothalamus - metabolism | Larva | Embryo, Nonmammalian | Sp7 Transcription Factor | Xenopus Proteins - metabolism | Zebrafish Proteins - genetics | Calcinosis - pathology | Osteoblasts - metabolism | Growth | Zebra fish | Physiological aspects | Bones | Genetic aspects | Research | Gene expression | Bioengineering | Phosphates | Larvae | Transcription | Transgenic | Homeostasis | Hypothalamus | Confocal | Cartilage | Biomedical materials | Mineralization | Rodents | Osteonectin | Biocompatibility | Neurons | Laser ablation | Bone turnover | Metabolism | Embryos | Ablation | Craniofacial growth | Osteoblastogenesis
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 149, Issue 7, pp. 1932 - 1943.e9
Background & Aims A hallmark of pancreatic ductal adenocarcinoma (PDAC) is the presence of a dense desmoplastic reaction (stroma) that impedes drug delivery to... 
Gastroenterology and Hepatology | Tumor Microenvironment | Stroma | Pancreatic Cancer | Drug Delivery | DUCTAL ADENOCARCINOMA | STELLATE CELLS | RECEPTOR | SRC KINASE | MASS-SPECTROMETRY | INHIBITION | GROWTH | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | CARCINOMA | PROGRESSION | Receptors, Transforming Growth Factor beta - genetics | Pancreatic Neoplasms - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Stromal Cells - pathology | Humans | Carcinoma, Pancreatic Ductal - metabolism | Drug Resistance, Neoplasm | Pyrimidines - metabolism | Carcinoma, Pancreatic Ductal - genetics | Gene Knockdown Techniques | Time Factors | Carcinoma, Pancreatic Ductal - mortality | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | STAT3 Transcription Factor - genetics | Antineoplastic Combined Chemotherapy Protocols - metabolism | Pancreatic Neoplasms - pathology | Osteonectin - metabolism | Mice, Transgenic | Pyrimidines - pharmacology | Tumor Burden | Signal Transduction - drug effects | Mice, Nude | Cell Line, Tumor | Deoxycytidine - analogs & derivatives | Phosphorylation | Deoxycytidine - pharmacology | Molecular Targeted Therapy | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Pancreatic Neoplasms - drug therapy | Deoxycytidine - metabolism | Transfection | Stromal Cells - drug effects | Pancreatic Neoplasms - mortality | STAT3 Transcription Factor - metabolism | Pyrazoles - pharmacology | Mice, Inbred C57BL | Stromal Cells - metabolism | Protein-Serine-Threonine Kinases - genetics | Pancreatic Neoplasms - genetics | Pyrazoles - metabolism | Transcription Factors - genetics | Carcinoma, Pancreatic Ductal - pathology | Xenograft Model Antitumor Assays | Carcinoma, Pancreatic Ductal - drug therapy | Collagen - metabolism | Animals | Neoplasm Staging | STAT3 Transcription Factor - antagonists & inhibitors | Drugs | Drug delivery systems | Pancreatic cancer | Genetic transcription | Drug therapy | Health aspects | Biomedical engineering | Vehicles
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2010, Volume 285, Issue 11, pp. 8196 - 8206
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 8, p. e104638
The fate of hypertrophic chondrocytes during endochondral ossification remains controversial. It has long been thought that the calcified cartilage is invaded... 
APOPTOSIS | RAT | ENDOCHONDRAL BONE-FORMATION | MULTIDISCIPLINARY SCIENCES | OSTEOBLASTS | OSSIFICATION | CHICK | CULTURE | PERICHONDRIUM | CARTILAGE | TRANSDIFFERENTIATION | Rabbits | Osteogenesis - physiology | Bone and Bones - physiology | Collagen Type I - metabolism | Osteocalcin - metabolism | Growth Plate - physiology | Caspase 3 - metabolism | Cell Proliferation - physiology | Osteonectin - metabolism | Male | Cartilage - metabolism | Growth Plate - metabolism | Hypertrophy - metabolism | Hypertrophy - physiopathology | Capillaries - physiology | Chondrogenesis - physiology | Neovascularization, Physiologic - physiology | Animals | Chondrocytes - physiology | Bone and Bones - metabolism | Cartilage - physiology | Capillaries - metabolism | Cell Differentiation - physiology | Chondrocytes - metabolism | Growth | Collagen | Collagen (type I) | Ulna | Phosphatase | Caspase-3 | Ossification | Proteins | Cartilage | Growth plate | Pore size | Bone growth | Rodents | Proliferating cell nuclear antigen | Osteonectin | Bone marrow | Biocompatibility | Bone matrix | Bone (endochondral) | Elongation | University graduates | Medical research | Osteocalcin | Cloning | Cell division | Blood vessels | Caspase | Orthopedics | Chondrocytes | Calcification | Extrusion | Porosity | Laboratory animals | Osteogenesis | Apoptosis
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2011, Volume 108, Issue 32, pp. E440 - E449
Astrocytes regulate synaptic connectivity in the CNS through secreted signals. Here we identified two astrocyte-secreted proteins, hevin and SPARC, as... 
Extracellular matrix | Synaptic cleft 1 | Matricellular protein | Osteonectin | SPARC-Like | osteonectin | SC1 | synaptic cleft 1 | RAT | EXTRACELLULAR-MATRIX GLYCOPROTEIN | INTEGRIN | MULTIDISCIPLINARY SCIENCES | RECEPTOR | matricellular protein | CELL-SURVIVAL | SUPERIOR COLLICULUS | SPARC-Like 1 | EXPRESSION | extracellular matrix | SUPERFICIAL LAYERS | BRAIN | Central Nervous System - ultrastructure | Central Nervous System - metabolism | Extracellular Matrix Proteins - deficiency | Humans | Superior Colliculi - ultrastructure | Calcium-Binding Proteins - antagonists & inhibitors | Culture Media, Conditioned - pharmacology | Retinal Ganglion Cells - metabolism | Retinal Ganglion Cells - cytology | Osteonectin - deficiency | Synapses - metabolism | HEK293 Cells | Neurogenesis - drug effects | Extracellular Matrix Proteins - metabolism | Astrocytes - cytology | Calcium-Binding Proteins - chemistry | Calcium-Binding Proteins - metabolism | Protein Structure, Tertiary | Astrocytes - drug effects | Retinal Ganglion Cells - ultrastructure | Synapses - drug effects | Extracellular Matrix Proteins - chemistry | Superior Colliculi - metabolism | Extracellular Matrix Proteins - antagonists & inhibitors | Superior Colliculi - drug effects | Osteonectin - metabolism | Rats | Calcium-Binding Proteins - deficiency | Synapses - ultrastructure | Osteonectin - chemistry | Rats, Sprague-Dawley | Astrocytes - ultrastructure | Animals | Central Nervous System - cytology | Superior Colliculi - cytology | Mice | Retinal Ganglion Cells - drug effects | Astrocytes - secretion | Biological Sciences | PNAS Plus
Journal Article
Colloids and surfaces, B, Biointerfaces, ISSN 0927-7765, 2017, Volume 149, pp. 233 - 242
Growth of human bone marrow mesenchymal stem cells in a hybrid organic/inorganic scaffold fabricated by Direct Laser Writing. [Display omitted] •Direct Laser... 
rhBMP-2 | Bone tissue engineering | Two-photon polymerization | Osteogenic differentiation | Hybrid 3D scaffolds | MATERIALS SCIENCE, BIOMATERIALS | OSTEOBLASTIC DIFFERENTIATION | CHEMISTRY, PHYSICAL | TITANIUM | BMP-2 | MESENCHYMAL STEM-CELLS | IN-VITRO | BIOPHYSICS | COATINGS | SURFACES | Bone Morphogenetic Protein 2 - pharmacology | Humans | Alkaline Phosphatase - metabolism | Osteocalcin - genetics | Extracellular Matrix - metabolism | Core Binding Factor Alpha 1 Subunit - metabolism | Tissue Scaffolds | Mesenchymal Stromal Cells - cytology | Osteonectin - genetics | Lasers | Bone Morphogenetic Protein 2 - metabolism | Bone Marrow Cells - drug effects | Collagen - genetics | Osteogenesis - genetics | Tissue Engineering | Recombinant Proteins - metabolism | Bone Morphogenetic Protein 2 - genetics | Mesenchymal Stromal Cells - drug effects | Alkaline Phosphatase - genetics | Bone Marrow Cells - cytology | Osteocalcin - metabolism | Extracellular Matrix - drug effects | Immobilized Proteins - genetics | Osteogenesis - drug effects | Gene Expression Regulation | Mesenchymal Stromal Cells - metabolism | Osteonectin - metabolism | Recombinant Proteins - genetics | Recombinant Proteins - pharmacology | Collagen - metabolism | Adsorption | Cell Differentiation - drug effects | Immobilized Proteins - pharmacology | Immobilized Proteins - metabolism | Cell Proliferation - drug effects | Primary Cell Culture | Bone Marrow Cells - metabolism | Core Binding Factor Alpha 1 Subunit - genetics | Medical colleges | Bone morphogenetic proteins | Stem cells | Proteins | Biomedical materials | Biocompatibility | Bones | Nanostructure | Gene expression | Scaffolds | Recombinant
Journal Article