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Bone, ISSN 8756-3282, 2003, Volume 33, Issue 6, pp. 889 - 898
Distraction osteogenesis is a unique and effective way to treat limb length inequality resulting from congenital and posttraumatic skeletal defects. However,... 
Angiogenesis | Extracellular matrix | Bone morphogenetic protein | Distraction osteogenesis | mRNA expression | angiogenesis | STABILITY | RECEPTOR | ANGIOPOIETIN-2 | MODEL | bone morphogenetic protein | distraction osteogenesis | CARTILAGE | VASCULARIZATION | GROWTH | ENDOCRINOLOGY & METABOLISM | BONE | DIFFERENTIATION | LIGAND | extracellular matrix | Immunohistochemistry | Receptor, Fibroblast Growth Factor, Type 4 | Sialoglycoproteins - genetics | Femur - pathology | Oligonucleotide Array Sequence Analysis | Osteocalcin - genetics | Male | Gene Expression Profiling | RNA, Messenger - metabolism | Vascular Endothelial Growth Factor A - genetics | Hypoxia-Inducible Factor 1, alpha Subunit | Osteogenesis, Distraction | Fibroblast Growth Factor 2 - analysis | Angiogenesis Inducing Agents - metabolism | Receptors, Fibroblast Growth Factor - genetics | Fracture Healing - physiology | Collagen - genetics | Femur - surgery | Neuropilins - genetics | Receptors, Vascular Endothelial Growth Factor - genetics | Bone Morphogenetic Proteins - genetics | Cytokines - genetics | Transforming Growth Factor beta2 | Osteogenesis - genetics | von Willebrand Factor - analysis | Gene Expression | Femur - metabolism | Neovascularization, Physiologic - genetics | RNA, Messenger - genetics | Osteopontin | Rats | Vascular Endothelial Growth Factor A - analysis | Transcription Factors - genetics | Rats, Sprague-Dawley | Receptors, TIE - genetics | Carrier Proteins - genetics | Animals | Transforming Growth Factor beta - genetics | Fibroblast Growth Factor 2 - genetics | Vascular Endothelial Growth Factors - genetics | Fracture Healing - genetics | Angiopoietins - genetics | Index Medicus
Journal Article
Archives of Oral Biology, ISSN 0003-9969, 2013, Volume 58, Issue 8, pp. 912 - 929
Abstract Objective An analysis of the genes involved in both osteoporosis and modifications of the jawbone, through text mining, using a web search tool, of... 
Advanced Basic Science | Dentistry | Bone resorption | Osteoporosis | Mandible | Bone remodelling | Genomics | Bone repair | Maxilla | Computational biology | BONE-MINERAL DENSITY | HUMAN OSTEOBLASTS | TOMOGRAPHIC FOLLOW-UP | SECONDARY HYPERPARATHYROIDISM | FACTOR-I | DENTISTRY, ORAL SURGERY & MEDICINE | CELL-CYCLE | HUMAN T-LYMPHOCYTES | EXPRESSION | ALVEOLAR RIDGE AUGMENTATION | GENOME-WIDE ASSOCIATION | Osteopontin - genetics | Bone Regeneration - genetics | Bone Morphogenetic Protein 7 - genetics | Genes, jun - genetics | Humans | Data Mining | Insulin-Like Growth Factor I - genetics | Interleukin-1beta - genetics | NF-kappa B p50 Subunit - genetics | Vascular Endothelial Growth Factor A - genetics | Collagen Type I - genetics | Bone Resorption - genetics | Jaw Diseases - genetics | Matrix Metalloproteinase 9 - genetics | Osteoporosis - genetics | Multigene Family - genetics | Bone Morphogenetic Protein 2 - genetics | Interleukin-6 - genetics | Computational Biology | Transforming Growth Factor beta1 - genetics | beta Catenin - genetics | RANK Ligand - genetics | Intercellular Adhesion Molecule-1 - genetics | Interleukin-10 - genetics | Bone Remodeling - genetics | Core Binding Factor Alpha 1 Subunit - genetics | Medical colleges | Analysis | Genes | Online searching | Genetic research | Internet/Web search services | Database searching | Data mining | Index Medicus
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 12/2010, Volume 191, Issue 7, pp. 1271 - 1283
Runx2 is indispensable for osteoblast lineage commitment and early differentiation but also blocks osteoblast maturation, thereby causing bone loss in Runx2... 
Osteomyelitis | Phenotypes | Antibodies | Bones | Mice | Repression | Bone marrow cells | Osteoblasts | Zinc | Mesenchymal stem cells | CLEIDOCRANIAL DYSPLASIA | CELLS | OSTEOBLAST DIFFERENTIATION | TGF-BETA | OSTEOCALCIN GENE | HOMEODOMAIN PROTEINS | CBFA1 | PARATHYROID-HORMONE | EXPRESSION | TRANSGENIC MICE | CELL BIOLOGY | Osteopontin - genetics | Bone and Bones - pathology | Transcription, Genetic - drug effects | Osteogenesis - physiology | Fractures, Spontaneous - genetics | Gene Expression - genetics | Protein Interaction Domains and Motifs - physiology | Bone Development - physiology | Cell Count | Alkaline Phosphatase - metabolism | Osteocalcin - genetics | Bone Remodeling - physiology | Core Binding Factor Alpha 1 Subunit - antagonists & inhibitors | Core Binding Factor Alpha 1 Subunit - metabolism | DNA-Binding Proteins - metabolism | Cell Differentiation - genetics | Mesenchymal Stromal Cells - cytology | Bone and Bones - metabolism | Osteoprotegerin - genetics | Osteoblasts - cytology | Response Elements - physiology | Animals, Newborn | Calcification, Physiologic - genetics | Histone Deacetylases - genetics | Extracellular Matrix Proteins - genetics | Rats | Histone Deacetylases - metabolism | Mice, Transgenic | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mice, Inbred Strains | Bone Diseases, Metabolic - metabolism | RANK Ligand - genetics | Animals | Sp7 Transcription Factor | Heterozygote | Histone Deacetylase Inhibitors - pharmacology | Zinc Fingers - physiology | Bone Diseases, Metabolic - genetics | Transcription, Genetic - genetics | Bone and Bones - abnormalities | Bone and Bones - embryology | Osteoblasts - metabolism | Core Binding Factor Alpha 1 Subunit - genetics | Protein Binding - physiology | Proteins | Enzymes | Transcription factors | Research | Properties | Density | Cell division | Maturation | Transgenic animals | Rodents | Index Medicus
Journal Article
Journal of Endodontics, ISSN 0099-2399, 2016, Volume 42, Issue 5, pp. 752 - 759
Abstract Introduction This study determined the gene expression profiles of the human coronal pulp (CP) and apical pulp complex (APC) with the aim of... 
Endocrinology & Metabolism | Dentistry | Apical pulp complex | human immature teeth | immunohistochemical staining | coronal pulp | complementary DNA microarray | Immunohistochemistry | Osteopontin - genetics | Synaptic Transmission - genetics | Humans | Real-Time Polymerase Chain Reaction - methods | Child, Preschool | Calbindin 1 - genetics | Male | Odontogenesis - genetics | Tooth Apex - growth & development | Gene Expression Profiling | Tooth Apex - anatomy & histology | Neurogenesis - genetics | Young Adult | Dental Pulp - diagnostic imaging | Hedgehog Proteins - genetics | Female | Receptors, Chemokine - genetics | Child | Republic of Korea | Microarray Analysis - methods | Tooth Apex - cytology | Cell Adhesion - genetics | Gene Expression | RNA - analysis | Extracellular Matrix Proteins - genetics | Dental Pulp - cytology | Phosphoproteins - genetics | Transcription Factors - genetics | Tooth Calcification - genetics | Homeodomain Proteins - genetics | Tooth Apex - diagnostic imaging | Laminin - genetics | Receptors, GABA-A - genetics | Adolescent | Dental Pulp - anatomy & histology | Collagen Type XII - genetics | CX3C Chemokine Receptor 1 | Dental Pulp - growth & development | Calcium-Binding Proteins - genetics | Genetic research | Medical colleges | Comparative analysis | Gene expression | Developmental biology | Genes
Journal Article
Journal Article
Clinical Oral Investigations, ISSN 1432-6981, 3/2013, Volume 17, Issue 2, pp. 405 - 410
The application of an enamel matrix derivative (EMD) for regenerative periodontal surgery has been shown to promote formation of new cementum, periodontal... 
Natural bone mineral | Gene array | Dentistry | Emdogain | Bone grafting materials | EMD | Enamel matrix proteins | GUIDED TISSUE REGENERATION | EXPRESSION PROFILES | PERIODONTAL-LIGAMENT CELLS | MOLECULES | CONTROLLED CLINICAL-TRIAL | IN-VITRO | DENTISTRY, ORAL SURGERY & MEDICINE | BOVINE-DERIVED XENOGRAFT | INTRABONY DEFECTS | OUTCOMES | PROTEINS | Osteopontin - genetics | Transforming Growth Factors - genetics | Cell Adhesion Molecules - genetics | Cell Proliferation | Oligonucleotide Array Sequence Analysis | Humans | Cell Differentiation - genetics | Minerals - therapeutic use | Osteonectin - genetics | Collagen - genetics | Cell Culture Techniques | Cadherins - genetics | Bone Morphogenetic Proteins - genetics | Cytokines - genetics | Osteogenesis - genetics | Calcification, Physiologic - genetics | Alkaline Phosphatase - genetics | Extracellular Matrix Proteins - genetics | Osteoblasts - physiology | Gene Expression Profiling - methods | Smad Proteins - genetics | Transcription Factors - genetics | Bone Matrix - physiology | Somatomedins - genetics | Integrin-Binding Sialoprotein - genetics | Vascular Endothelial Growth Factors - genetics | Dental Enamel Proteins - therapeutic use | DNA microarrays | Endothelial growth factors | Collagen | Analysis | Genes | Physiological aspects | Bone morphogenetic proteins | Genetic transcription
Journal Article
International Journal of Oral & Maxillofacial Surgery, ISSN 0901-5027, 2011, Volume 40, Issue 6, pp. 605 - 611
Abstract Bisphosphonate induced osteonecrosis of the jaw (BONJ) is a complication in patients taking bisphosphonate (BP) that affects their quality of life and... 
Surgery | Osteonecrosis of the jaw (ONJ) | Bisphosphonates | Genetic polymorphisms | Multiple myeloma | Pharmacogenomics | MULTIPLE-MYELOMA | SURGERY | CELLS | RESORPTION | BONE-MINERAL DENSITY | OSTEOPONTIN | DENTISTRY, ORAL SURGERY & MEDICINE | BINDING | Osteopontin - genetics | Cytochrome P-450 CYP2C8 | Gene Frequency - genetics | Injections, Intravenous | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Aryl Hydrocarbon Hydroxylases - genetics | Imidazoles - administration & dosage | Male | Jaw Diseases - chemically induced | Osteonecrosis - genetics | Multiple Myeloma - drug therapy | Collagen Type I - genetics | Time Factors | Jaw Diseases - genetics | Osteoprotegerin - genetics | Adult | Female | Diphosphonates - adverse effects | Bone Density Conservation Agents - adverse effects | Imidazoles - adverse effects | Risk Factors | Diphosphonates - administration & dosage | Bone Density Conservation Agents - administration & dosage | Matrix Metalloproteinase 2 - genetics | Receptor Activator of Nuclear Factor-kappa B - genetics | Polymorphism, Single Nucleotide - genetics | Polymorphism, Genetic - genetics | Aged | Osteonecrosis - chemically induced | Cohort Studies | Smoking | Phosphonates | Genetic research | Physiological aspects | Bones | Genetic aspects | Risk factors | Necrosis | Index Medicus | Dentistry
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 08/2009, Volume 87, Issue 8, pp. 803 - 813
Lipocalin-2 (LCN2) is a novel adipokine with potential roles in obesity, insulin resistance, and inflammation. The aim of the present work was to evaluate the... 
Obesity | Inflammation | Visceral adipose tissue | Gene expression | Lipocalin-2 | SERUM RETINOL-BINDING-PROTEIN-4 | MEDICINE, RESEARCH & EXPERIMENTAL | GASTRIC BYPASS | METABOLIC SYNDROME | IRON | GELATINASE-ASSOCIATED LIPOCALIN | OSTEOPONTIN | INSULIN-RESISTANCE | GENETICS & HEREDITY | GENE-EXPRESSION | TYPE-2 DIABETES-MELLITUS | ADIPOCYTE | Osteopontin - genetics | Tumor Necrosis Factor-alpha - metabolism | Humans | Tumor Necrosis Factor-alpha - genetics | Male | Osteopontin - metabolism | Acute-Phase Proteins - genetics | Antigens, CD - genetics | Obesity - genetics | Antigens, CD - metabolism | Matrix Metalloproteinase 9 - metabolism | Lipocalins - blood | Lipocalins - genetics | Matrix Metalloproteinase 9 - genetics | Adult | Female | Matrix Metalloproteinase 9 - blood | Lipocalins - metabolism | Proto-Oncogene Proteins - metabolism | Acute-Phase Proteins - metabolism | Matrix Metalloproteinase 2 - metabolism | RNA, Messenger - genetics | Gene Expression Regulation | Obesity - physiopathology | Proto-Oncogene Proteins - genetics | Intra-Abdominal Fat - metabolism | Antigens, Differentiation, Myelomonocytic - genetics | Obesity - metabolism | Matrix Metalloproteinase 2 - blood | Matrix Metalloproteinase 2 - genetics | Antigens, Differentiation, Myelomonocytic - metabolism | Protein Binding | Proto-Oncogene Proteins - blood | Adipose tissues | Care and treatment | Physiological aspects | Genetic aspects | Research | Index Medicus
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 03/2009, Volume 15, Issue 5, pp. 1755 - 1761
Purpose: Brain metastases affect 25% of patients with non–small cell lung cancer (NSCLC). We hypothesized that the expression of genes in primary NSCLC tumors... 
non–small cell lung cancer | biomarkers | brain metastasis | PROPHYLACTIC CRANIAL IRRADIATION | BREAST-CANCER | SURVIVAL | OSTEOPONTIN | MITOTIC CHECKPOINT GENES | ONCOLOGY | MESSENGER-RNA EXPRESSION | ACUTE LYMPHOBLASTIC-LEUKEMIA | CENTRAL-NERVOUS-SYSTEM | N-CADHERIN | MOLECULAR ANALYSIS | Prognosis | Cadherins - metabolism | Antigens, Nuclear - metabolism | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | Male | Gene Expression Profiling | RNA, Messenger - metabolism | Antigens, CD - genetics | Immunoenzyme Techniques | Antigens, CD - metabolism | Carcinoma, Squamous Cell - diagnosis | Brain Neoplasms - secondary | Lung Neoplasms - secondary | Biomarkers, Tumor - metabolism | Kinesin - genetics | Female | Adenocarcinoma - genetics | Cadherins - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Brain Neoplasms - diagnosis | RNA, Messenger - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Brain Neoplasms - genetics | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Nerve Tissue Proteins - genetics | Adenocarcinoma - secondary | Kinesin - metabolism | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Adenocarcinoma - diagnosis | Antigens, Nuclear - genetics | Carcinoma, Squamous Cell - secondary | Biomarkers, Tumor - genetics | Lung Neoplasms - diagnosis | Index Medicus
Journal Article
Science, ISSN 0036-8075, 8/2013, Volume 341, Issue 6147, pp. 789 - 792
Journal Article
Stem Cell Research and Therapy, ISSN 1757-6512, 02/2017, Volume 8, Issue 1, pp. 39 - 39
Background: Magnesium is essential for numerous physiological functions. Magnesium exists mostly in bone and the amount is dynamically regulated by skeletal... 
Mesenchymal stromal cells | Magnesium transporter | SLC41A1 | Mineralization | Osteogenic differentiation | MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | MARROW | MATRIX GLA PROTEIN | PROLIFERATION | CELL BIOLOGY | IN-VITRO | EXTRACELLULAR MAGNESIUM | MOLECULAR-IDENTIFICATION | CALCIUM | CALCIFICATION | DIFFERENTIATION | Osteopontin - genetics | RNA, Small Interfering - genetics | Cation Transport Proteins - antagonists & inhibitors | Humans | Alkaline Phosphatase - metabolism | Osteocalcin - genetics | Male | Osteopontin - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Mesenchymal Stromal Cells - cytology | Collagen Type I - genetics | Protein Isoforms - metabolism | Cation Transport Proteins - metabolism | Bone Morphogenetic Protein 2 - metabolism | Bone Marrow Cells - drug effects | Cation Transport Proteins - genetics | Cell Differentiation | Ion Transport | Extracellular Matrix Proteins - metabolism | Osteogenesis - genetics | Wnt Signaling Pathway | Calcification, Physiologic - genetics | Calcium-Binding Proteins - metabolism | Bone Morphogenetic Protein 2 - genetics | Mesenchymal Stromal Cells - drug effects | Alkaline Phosphatase - genetics | Collagen Type I - metabolism | Calcification, Physiologic - drug effects | Bone Marrow Cells - cytology | Osteocalcin - metabolism | Extracellular Matrix Proteins - genetics | Osteogenesis - drug effects | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Mesenchymal Stromal Cells - metabolism | Magnesium - metabolism | Transcription Factors - genetics | Magnesium - pharmacology | Transcription Factors - metabolism | Animals | Sp7 Transcription Factor | Mice | Mice, Inbred BALB C | Bone Marrow Cells - metabolism | Protein Isoforms - antagonists & inhibitors | Calcium-Binding Proteins - genetics | Protein Isoforms - genetics | RNA, Small Interfering - metabolism | Growth | Analysis | Physiological aspects | Bone morphogenetic proteins | Bones | Genetic aspects | Research | Gene expression | Magnesium compounds | Density | Index Medicus
Journal Article