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European Journal of Endocrinology, ISSN 0804-4643, 06/2017, Volume 176, Issue 6, pp. 685 - 693
Objective, design and methods: Roux-en-Y gastric bypass (RYGB) has proved successful in attaining sustained weight loss but may lead to metabolic bone disease.... 
MINERAL DENSITY | METABOLISM | DISTAL RADIUS | MICROARCHITECTURE | ENDOCRINOLOGY & METABOLISM | WEIGHT-LOSS | BARIATRIC SURGERY | MORBID-OBESITY | QUANTITATIVE COMPUTED-TOMOGRAPHY | POSTMENOPAUSAL WOMEN | FRACTURE RISK | Postoperative Complications - etiology | Obesity, Morbid - surgery | Humans | Leptin - metabolism | Middle Aged | Postoperative Complications - metabolism | Male | Tomography, X-Ray Computed | Luteinizing Hormone - metabolism | Osteoporosis - etiology | Peptides - metabolism | Osteoporosis - metabolism | Parathyroid Hormone - metabolism | Osteoporosis - diagnostic imaging | Adiponectin - metabolism | Adult | Female | Follicle Stimulating Hormone - metabolism | Peptide Fragments - metabolism | Bone Density | Bone Diseases, Metabolic - diagnostic imaging | Collagen Type I - metabolism | Lumbar Vertebrae - diagnostic imaging | Bone Diseases, Metabolic - etiology | Tibia - diagnostic imaging | Gastric Bypass - adverse effects | Procollagen - metabolism | Absorptiometry, Photon | Bone Diseases, Metabolic - metabolism | Hip Joint - diagnostic imaging | Insulin - metabolism | Weight Loss | Vitamin D - analogs & derivatives | Vitamin D - metabolism | Bone Remodeling | Longitudinal Studies | Postoperative Complications - diagnostic imaging | Radius - diagnostic imaging | Dual energy X-ray absorptiometry | Radius | Spine | Body weight | Gastric bypass | Body weight loss | Bone turnover | Metabolism | Bone surgery | Insulin | Hip | Osteoporosis | Bone mass | Fractures | Computed tomography | Tibia | Leptin | Bone mineral density | Gastrointestinal surgery | Bone loss | Bone strength | Index Medicus
Journal Article
Aging Cell, ISSN 1474-9718, 08/2015, Volume 14, Issue 4, pp. 644 - 658
The healthspan of mice is enhanced by killing senescent cells using a transgenic suicide gene. Achieving the same using small molecules would have a tremendous... 
dasatinib | plasminogen‐activated inhibitor | dependence receptors | quercetin | ephrins | 3K delta | p21 | Dasatinib | Dependence receptors | Ephrins | Plasminogen-activated inhibitor | Quercetin | PI3K delta | P21 | ENDOTHELIAL DYSFUNCTION | PLASMINOGEN-ACTIVATOR INHIBITOR-1 | EXPRESSION PROFILES | plasminogen-activated inhibitor | CELLULAR SENESCENCE | CANCER-THERAPY | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | LUNG-CANCER | SET ENRICHMENT ANALYSIS | GENE-EXPRESSION | IONIZING-RADIATION | TUMOR-GROWTH | Carotid Arteries - drug effects | Endonucleases - genetics | Plasminogen Activator Inhibitor 2 - genetics | Transcriptome | Gene Expression Profiling | Adipocytes - drug effects | Aging - genetics | Osteoporosis - metabolism | Ephrins - metabolism | Plasminogen Activator Inhibitor 2 - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Osteoporosis - genetics | Intervertebral Disc - pathology | Fibroblasts - metabolism | Endothelial Cells - metabolism | Intervertebral Disc - chemistry | Fibroblasts - pathology | Mesenchymal Stem Cells - pathology | Mice, Knockout | Dasatinib - pharmacology | Osteoporosis - pathology | Ephrins - genetics | Fibroblasts - drug effects | Mice | Endothelial Cells - pathology | bcl-X Protein - metabolism | Aging - metabolism | Aging - drug effects | bcl-X Protein - genetics | Cellular Senescence - drug effects | Phosphatidylinositol 3-Kinases - metabolism | Endonucleases - metabolism | DNA-Binding Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Mesenchymal Stem Cells - drug effects | Mesenchymal Stem Cells - metabolism | Heart - physiopathology | Cellular Senescence - genetics | Osteoporosis - prevention & control | DNA-Binding Proteins - genetics | Adipocytes - pathology | Aging - pathology | Phosphatidylinositol 3-Kinases - genetics | Animals | Quercetin - pharmacology | Adipocytes - metabolism | Heart - drug effects | Carotid Arteries - pathology | Intervertebral Disc - drug effects | Drug Combinations | Endothelial Cells - drug effects | Index Medicus | Original
Journal Article
1990, Progress in basic and clinical pharmacology, ISBN 3805551460, Volume 4, viii, 187
Book
Journal Article
American Journal of Gastroenterology, ISSN 0002-9270, 02/2015, Volume 110, Issue 2, pp. 336 - 345
Journal Article
Cardiovascular Research, ISSN 0008-6363, 11/2011, Volume 92, Issue 2, pp. 296 - 306
Aims Omentin-1 (also known as intelectin-1) is a recently identified visceral adipose tissue-derived cytokine that is inversely related to obesity. Our... 
Omentin-1 | Bone | Receptor activator for nuclear factor κB ligand | Arterial calcification | Osteoprotegerin | CARDIAC & CARDIOVASCULAR SYSTEMS | HUMAN OSTEOBLASTS | BIOCHEMICAL MARKERS | MAPK SIGNALING PATHWAY | VISFATIN LEVELS | Receptor activator for nuclear factor kappa B ligand | MINERAL DENSITY | BODY-MASS INDEX | SMOOTH-MUSCLE-CELLS | OSTEOCLAST DIFFERENTIATION | SERUM ADIPONECTIN | ADIPOSE-TISSUE | Genetic Therapy | Osteoprotegerin - deficiency | Cell Proliferation | RANK Ligand - metabolism | Muscle, Smooth, Vascular - metabolism | Humans | Vascular Calcification - genetics | Tartrate-Resistant Acid Phosphatase | Lectins - metabolism | Vascular Calcification - metabolism | Acid Phosphatase - metabolism | Osteoporosis - metabolism | Time Factors | Isoenzymes - metabolism | Osteoprotegerin - genetics | Adiponectin - metabolism | Female | Osteoporosis - genetics | Cell Differentiation | Proto-Oncogene Proteins c-akt - metabolism | Cytokines - genetics | Myocytes, Smooth Muscle - metabolism | Phosphatidylinositol 3-Kinase - metabolism | Disease Models, Animal | Recombinant Proteins - metabolism | Bone Density | Cytokines - metabolism | Osteoporosis - prevention & control | Signal Transduction | Osteocalcin - metabolism | Down-Regulation | Mice, Inbred C57BL | Cells, Cultured | Vascular Calcification - prevention & control | GPI-Linked Proteins - metabolism | Mice, Knockout | Animals | Lectins - genetics | Mice | Osteoblasts - metabolism | GPI-Linked Proteins - genetics | Index Medicus
Journal Article
American Journal of Gastroenterology, ISSN 0002-9270, 01/2017, Volume 112, Issue 1, pp. 95 - 101
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2018, Volume 72, Issue 2, pp. 355 - 368.e4
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2005, Volume 280, Issue 22, pp. 21162 - 21168
Mutations in the Wnt co-receptor LRP5 alter bone mass in humans, but the mechanisms responsible for Wnts actions in bone are unclear. To investigate the role... 
MOUSE DEVELOPMENT | GASTRULATION | PROGRESSIVE DEVELOPMENT | LRP5 GENE | OSTEOPOROSIS-PSEUDOGLIOMA SYNDROME | APC GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUTATION | RECEPTOR-RELATED PROTEIN-5 | OSTEOBLAST PROLIFERATION | MICE | Immunohistochemistry | Adenomatous Polyposis Coli Protein - physiology | Receptor Activator of Nuclear Factor-kappa B | Membrane Glycoproteins - metabolism | Glycoproteins - metabolism | Male | RANK Ligand | Tomography, X-Ray Computed | Wnt Proteins | Genes, APC | Intercellular Signaling Peptides and Proteins - physiology | Osteoprotegerin | Trans-Activators - physiology | Time Factors | Bone and Bones - metabolism | Cytoskeletal Proteins - metabolism | Female | Cell Differentiation | Cytoskeletal Proteins - physiology | Adenomatous Polyposis Coli Protein - genetics | Animals, Newborn | Receptors, Tumor Necrosis Factor - metabolism | Green Fluorescent Proteins - metabolism | Enzyme-Linked Immunosorbent Assay | Signal Transduction | beta Catenin | Femur - metabolism | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Genotype | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | Osteoclasts - metabolism | Bone Diseases, Metabolic - metabolism | Animals | Carrier Proteins - metabolism | Sex Factors | Trans-Activators - metabolism | Mice | Bone Diseases, Metabolic - genetics | Mutation | Osteoblasts - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e92368 - e92368
The gut microbiota (GM) modulates the hosts metabolism and immune system. Probiotic bacteria are defined as live microorganisms which when administered in... 
C-REACTIVE PROTEIN | TRABECULAR BONE | WOMEN | MINERAL DENSITY | IMMUNE-SYSTEM | MULTIDISCIPLINARY SCIENCES | ESTROGEN-RECEPTOR-ALPHA | OSTEOPROTEGERIN LIGAND | REGULATORY T-CELLS | GUT MICROBIOTA | TNF-ALPHA | Bone and Bones - pathology | Ovariectomy - adverse effects | T-Lymphocytes, Regulatory - metabolism | RANK Ligand - metabolism | Body Weight - drug effects | Bone and Bones - drug effects | Lactobacillus - drug effects | Bone Marrow - metabolism | Bone and Bones - metabolism | Inflammation Mediators - metabolism | Female | Minerals - metabolism | Bone Marrow - drug effects | Bone Resorption - etiology | Bone Resorption - blood | Cytokines - metabolism | Mice, Inbred C57BL | Bone Resorption - drug therapy | Biomarkers - blood | Probiotics - pharmacology | Lactobacillus - metabolism | Bone Resorption - prevention & control | Organ Size - drug effects | T-Lymphocytes, Regulatory - drug effects | Animals | Bone Marrow - pathology | Probiotics - therapeutic use | Mice | Osteoprotegerin - metabolism | Transforming Growth Factor beta - metabolism | Probiotics | Ovariectomy | Microbiota (Symbiotic organisms) | Physiological aspects | Bones | T cells | Density | Drinking water | Calcium | Lymphocytes T | Genomes | Arthritis | Immune status | Osteoprotegerin | Bone resorption | Osteoporosis | Microorganisms | Biomedical materials | Microbiota | Lymphocytes | Bone marrow | Bacteria | Tumor necrosis factor-TNF | Biocompatibility | Bone density | Bone loss | Bone (cortical) | Bone composition | Food | Immune system | Calcium (urinary) | Excretion | Gnotobiotics | Cytokines | Nutrition | Immunoregulation | Rheumatology | Inflammation | Tumor necrosis factor-α | IL-1β | Metabolism | Gene expression | Bone mineral content | Medicine | Serum levels | Osteoclastogenesis | Bone mass | Antibiotics | Womens health | Ligands | Bone | Index Medicus | Endokrinologi och diabetes | Endocrinology and Diabetes
Journal Article