X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (6169) 6169
Publication (524) 524
Newsletter (142) 142
Book Chapter (23) 23
Streaming Video (20) 20
Book Review (13) 13
Conference Proceeding (8) 8
Dissertation (4) 4
Magazine Article (3) 3
Newspaper Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (3998) 3998
osteosarcoma (3641) 3641
index medicus (2649) 2649
biochemistry & molecular biology (2133) 2133
animals (2031) 2031
osteosarcoma - pathology (1773) 1773
cell line, tumor (1742) 1742
cancer (1383) 1383
osteosarcoma - metabolism (1335) 1335
cell biology (1301) 1301
apoptosis (1228) 1228
oncology (1151) 1151
expression (1105) 1105
bone neoplasms - pathology (1069) 1069
mice (1018) 1018
tumor cells, cultured (991) 991
osteosarcoma - genetics (981) 981
female (980) 980
male (893) 893
bone cancer (892) 892
metastasis (784) 784
tumors (711) 711
bone neoplasms - metabolism (688) 688
cell proliferation (674) 674
osteosarcoma - drug therapy (654) 654
osteosarcoma cells (651) 651
gene expression (633) 633
proteins (629) 629
rats (621) 621
chemotherapy (611) 611
analysis (604) 604
bone neoplasms - genetics (600) 600
biocompatibility (548) 548
research (526) 526
proliferation (525) 525
cell line (505) 505
growth (497) 497
gene expression regulation, neoplastic (464) 464
cells (462) 462
signal transduction (444) 444
biomedical materials (437) 437
biochemistry (430) 430
adult (427) 427
molecular sequence data (427) 427
cell cycle (422) 422
apoptosis - drug effects (421) 421
transfection (417) 417
bone neoplasms - drug therapy (410) 410
in-vitro (405) 405
biophysics (401) 401
research article (396) 396
activation (391) 391
cell proliferation - drug effects (386) 386
adolescent (369) 369
genetics & heredity (362) 362
base sequence (359) 359
differentiation (355) 355
prognosis (348) 348
osteoblasts - metabolism (346) 346
phosphorylation (333) 333
invasion (331) 331
antineoplastic agents - pharmacology (327) 327
inhibition (327) 327
protein (327) 327
cells, cultured (318) 318
pharmacology & pharmacy (314) 314
child (307) 307
article (305) 305
middle aged (305) 305
genetic aspects (300) 300
down-regulation (294) 294
health aspects (294) 294
immunohistochemistry (294) 294
cell growth (290) 290
amino acid sequence (285) 285
mice, nude (282) 282
kinases (280) 280
bone (278) 278
genes (275) 275
medicine (273) 273
metastases (270) 270
cell survival - drug effects (266) 266
micrornas - genetics (265) 265
cancer research (264) 264
gene-expression (261) 261
development and progression (259) 259
rna, messenger - genetics (259) 259
osteosarcoma - chemistry (258) 258
multidisciplinary sciences (257) 257
breast-cancer (254) 254
care and treatment (254) 254
blotting, western (248) 248
rna (247) 247
osteoblasts - drug effects (245) 245
osteoblasts (244) 244
endocrinology & metabolism (241) 241
kinetics (240) 240
life sciences (238) 238
dose-response relationship, drug (237) 237
biomedicine (232) 232
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (6291) 6291
Japanese (34) 34
Chinese (25) 25
Russian (9) 9
German (8) 8
French (7) 7
Polish (3) 3
Czech (1) 1
Hungarian (1) 1
Italian (1) 1
Korean (1) 1
Portuguese (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of the American Chemical Society, ISSN 0002-7863, 02/2015, Volume 137, Issue 5, pp. 2056 - 2066
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 2014, Volume 57, Issue 16, pp. 6930 - 6948
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 01/2018, Volume 140, Issue 4, pp. 1438 - 1446
Journal Article
Cancer, ISSN 0008-543X, 10/2017, Volume 123, Issue 19, pp. 3807 - 3815
BACKGROUND Programmed death 1 (PD‐1) signaling in the tumor microenvironment dampens immune responses to cancer, and blocking this axis induces antitumor... 
checkpoint | neuroblastoma | tumor‐infiltrating lymphocytes | programmed death 1/programmed death 1 ligand (PD‐1/PD‐L1) blockade | immunotherapy | pediatric cancer | tumor-infiltrating lymphocytes | programmed death 1/programmed death 1 ligand (PD-1/PD-L1) blockade | ONCOLOGY-GROUP | PD-L1 EXPRESSION | INFILTRATING LYMPHOCYTES | WILMS-TUMOR | UNTREATED MELANOMA | LUNG-CANCER | ONCOLOGY | NEUROECTODERMAL TUMOR | ADULT GLIOBLASTOMA | T-CELLS | CLINICAL-SIGNIFICANCE | Immunohistochemistry | Bone Neoplasms - mortality | Tissue Array Analysis | Humans | Sarcoma, Ewing - pathology | Rhabdomyosarcoma - pathology | Neuroblastoma - mortality | Osteosarcoma - chemistry | Macrophages | Bone Neoplasms - pathology | Burkitt Lymphoma - pathology | Neoplasms - chemistry | Lymphocytes, Tumor-Infiltrating | Burkitt Lymphoma - immunology | Neuroblastoma - immunology | Bone Neoplasms - chemistry | Glioblastoma - chemistry | Child | Neuroblastoma - pathology | Rhabdomyosarcoma - immunology | Sarcoma, Ewing - chemistry | Neuroblastoma - chemistry | Neoplasms - mortality | Bone Neoplasms - immunology | Burkitt Lymphoma - chemistry | Sarcoma, Ewing - immunology | Osteosarcoma - immunology | Glioblastoma - immunology | Neoplasms - immunology | Glioblastoma - pathology | Neoplasm Proteins - analysis | B7-H1 Antigen - analysis | Rhabdomyosarcoma - chemistry | Neoplasms - pathology | Osteosarcoma - pathology | Chemotherapy | Usage | Care and treatment | Diagnosis | Research | Gene expression | Cancer in children | Cancer | Pediatrics | Parkinson's disease | PD-1 protein | Glioblastoma | Neuroblastoma | Tissues | Anticancer properties | Metastases | Lymphocytes | Children | Movement disorders | Immune system | Immune response | Neurodegenerative diseases | Tumor cells | Mortality | Patients | Survival | Glioblastoma multiforme | Lymphoma | Burkitt's lymphoma | PD-L1 protein | Biomarkers | Ligands | Death | Antitumor activity | Infiltration | Lymphomas | Diagnostic systems | Tumors | Apoptosis
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 07/2019, Volume 20, Issue 13, p. 3312
Methotrexate (MTX) is a folic acid antagonist used as an effective drug to treat various kinds of cancers. However, MTX has limited use in cancer chemotherapy... 
MICROSPHERES | DRUG-DELIVERY | DOSE METHOTREXATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR | methotrexate | lymphatic delivery | RELEASE | FORMULATION | CANCER | CHEMISTRY, MULTIDISCIPLINARY | PLGA-BASED NANOPARTICLES | PLGA | nanoparticles | ORAL BIOAVAILABILITY | SYSTEMS | Methotrexate - pharmacology | Cell Survival - drug effects | Polyvinyl Alcohol - chemistry | Nanoparticles - chemistry | Humans | Nanoparticles - ultrastructure | Polylactic Acid-Polyglycolic Acid Copolymer - chemistry | Spectroscopy, Fourier Transform Infrared | Methotrexate - blood | Drug Delivery Systems | Lymphatic Vessels - drug effects | Particle Size | Reference Standards | X-Ray Diffraction | Water - chemistry | Cell Line, Tumor | Drug Liberation | Lymph Nodes - drug effects | Methotrexate - administration & dosage | Polymers - chemistry | Cell Death - drug effects | Oils - chemistry | Methotrexate - chemistry | Infrared spectroscopy | Fourier transforms | Drug delivery systems | Particle size | Intravenous administration | Toxicity | Lung cancer | Leukemia | X-ray diffraction | Spectroscopic analysis | Selectivity | Drug resistance | Infrared analysis | Inflammatory diseases | Folic acid | Nanoparticles | Biomedical materials | Efficiency | Osteosarcoma | Spectrum analysis | Biocompatibility | Dihydrofolate reductase | Methotrexate | Drug dosages | Hepatotoxicity | Formulations | Lymphatic system | Multidrug resistance | Pharmacology | Breast cancer | Bioavailability | Permeability | Chemical compounds | Organic chemistry | Acids | Thermal analysis | Solid tumors | Pharmacokinetics | Cancer | Ulcerative colitis | Tumors
Journal Article
Journal Article
Journal Article
Journal Article
Molecules, ISSN 1420-3049, 09/2013, Volume 18, Issue 9, pp. 10580 - 10598
Journal Article
Journal Article