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Nature Genetics, ISSN 1061-4036, 04/2012, Volume 44, Issue 4, pp. 461 - 466
Journal Article
Oncogene, ISSN 0950-9232, 10/2011, Volume 30, Issue 41, pp. 4261 - 4274
In the presence of sustained DNA damage occurring in S-phase or G2, normal cells arrest before mitosis and eventually become senescent. The checkpoint kinases... 
cyclin B1 | ATM | Chk2 | G2-M checkpoint | cell cycle | GENOTOXIC STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOTIC CATASTROPHE | TRANSCRIPTIONAL REPRESSION | G CHECKPOINT | CELL BIOLOGY | GENOMIC INSTABILITY | RETINOBLASTOMA PROTEIN | ONCOLOGY | GENETICS & HEREDITY | P53-DEFICIENT CELLS | CELL-CYCLE EXIT | IONIZING-RADIATION | ATAXIA-TELANGIECTASIA | Protein Kinases - metabolism | G2 Phase Cell Cycle Checkpoints - physiology | Phosphorylation | Protein Kinases - genetics | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Immunoblotting | Male | Cyclin B1 - metabolism | Pyrones - pharmacology | Tumor Suppressor Protein p53 - genetics | Cell Cycle Proteins - antagonists & inhibitors | DNA-Binding Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | G2 Phase Cell Cycle Checkpoints - drug effects | RNA Interference | Tumor Suppressor Proteins - genetics | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Antineoplastic Agents - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Tumor Suppressor Proteins - metabolism | DNA-Binding Proteins - antagonists & inhibitors | HCT116 Cells | Cell Cycle Proteins - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Cyclin B1 - genetics | Morpholines - pharmacology | Signal Transduction - genetics | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Piperazines - pharmacology | G2 Phase Cell Cycle Checkpoints - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Checkpoint Kinase 2 | Bleomycin - pharmacology | Checkpoint Kinase 1 | Signal Transduction - physiology | DNA Damage | HeLa Cells | Cell division | Oxidative stress | Signal transduction | DNA damage | Cyclin-dependent kinases | Cell cycle | CHK2 protein | Epithelial cells | Mitosis | CHK1 protein | G2 phase | Genotoxicity | Osteosarcoma cells | p53 protein | Cyclin-dependent kinase | Chemotherapy | Fibroblasts | Cancer
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, p. e95843
Osteosarcoma is the most common malignancy of bone, and occurs most frequently in children and adolescents. Currently, the most reliable technique for... 
TRANSCRIPTION FACTOR RUNX2 | OSTEOBLAST DIFFERENTIATION | PROGNOSTIC-FACTORS | MULTIDISCIPLINARY SCIENCES | PROTEIN EXPRESSION | COPY NUMBER | GENE-EXPRESSION | TUMOR-SUPPRESSOR | HIGH-GRADE OSTEOSARCOMA | CELL-CYCLE KINASES | CHROMOSOMAL INSTABILITY | Osteosarcoma - drug therapy | RNA-Binding Proteins - genetics | Proto-Oncogene Proteins c-mdm2 - genetics | Gene Regulatory Networks - genetics | Cyclin-Dependent Kinase 4 - genetics | Humans | Gene Expression Profiling - methods | Male | RecQ Helicases - genetics | Treatment Outcome | Drug Therapy - methods | Genetic Markers - genetics | Neoadjuvant Therapy - methods | Adolescent | Cell Cycle Proteins - genetics | Female | Osteosarcoma - genetics | Child | Core Binding Factor Alpha 1 Subunit - genetics | Gene Expression Regulation, Neoplastic - genetics | Pediatrics | Prognosis | RNA | Osteosarcoma | Analysis | Adjuvant treatment | Tumor proteins | Biological markers | Gene expression | Genetic screening | Cancer | Adolescence | Transcription factors | Transcription | Laboratories | p53 Protein | Genes | Bar codes | AKT protein | Biology | Malignancy | Myc protein | Bone surgery | Cyclin-dependent kinase 4 | Necrosis | Cyclin-dependent kinase | DNA helicase | Cell cycle | Gangrene | Biocompatibility | Tumorigenesis | Bioindicators | Children | Adolescents | Deoxyribonucleic acid--DNA | Cbfa-1 protein | MDM2 protein | Patients | 1-Phosphatidylinositol 3-kinase | Medicine | Signaling | Bone cancer | Chemotherapy | Hospitals | MicroRNAs | Biomarkers | Bone | PTEN protein | Tumors | Apoptosis | Deoxyribonucleic acid | DNA
Journal Article
Oncogene, ISSN 0950-9232, 2018, Volume 38, Issue 14, pp. 2627 - 2644
Yes-associated protein 1 (YAP1) exerts significant effects in various malignancies. However, the oncogenic role of YAP1 remains controversial, and the... 
YAP1 | METASTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | OSTEOSARCOMA DEVELOPMENT | CELL-PROLIFERATION | EXPRESSION PROFILES | CELL BIOLOGY | ONCOGENE | LONG NONCODING RNA | ONCOLOGY | POOR-PROGNOSIS | GENETICS & HEREDITY | TUMOR-GROWTH | PROGRESSION | Colorectal Neoplasms - genetics | Epithelial-Mesenchymal Transition - physiology | Humans | Middle Aged | Male | Epithelial-Mesenchymal Transition - genetics | Cell Movement - genetics | Neovascularization, Pathologic - pathology | Young Adult | Neoplasm Invasiveness - pathology | HEK293 Cells | Aged, 80 and over | Adult | Female | Gene Expression Regulation, Neoplastic - genetics | Caco-2 Cells | Cell Line | Cell Proliferation - genetics | HCT116 Cells | RNA, Long Noncoding - genetics | Phosphoproteins - genetics | HT29 Cells | Adaptor Proteins, Signal Transducing - genetics | Adolescent | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Aged | MicroRNAs - genetics | Transcription, Genetic - genetics | Colorectal Neoplasms - pathology | Neoplasm Invasiveness - genetics | MicroRNA | Reorganization and restructuring | Patient outcomes | Colorectal cancer | Cancer cells | Development and progression | Genetic aspects | Diagnosis | Research | Cell proliferation | Chromatin | Immunoprecipitation | Mesenchyme | Therapeutic applications | Colorectal carcinoma | Cytotoxicity | Lymphocytes T | Ribonucleic acid--RNA | Metastases | Yes-associated protein | β-catenin | Angiogenesis | Colon cancer | Transfection | Bioinformatics | Cell migration | Index Medicus | siRNAs
Journal Article
by Sampson, Joshua N and Wheeler, William A and Yeager, Meredith and Panagiotou, Orestis and Wang, Zhaoming and Berndt, Sonja I and Lan, Qing and Abnet, Christian C and Amundadottir, Laufey T and Figueroa, Jonine D and Landi, Maria Teresa and Mirabello, Lisa and Savage, Sharon A and Taylor, Philip R and Vivo, Immaculata De and McGlynn, Katherine A and Purdue, Mark P and Rajaraman, Preetha and Adami, Hans-Olov and Ahlbom, Anders and Albanes, Demetrius and Amary, Maria Fernanda and An, She-Juan and Andersson, Ulrika and Aniole, Gerald and Anulis, Irene L and Angelucci, Emanuele and Ansell, Stephen M and Arici, Cecilia and Armstrong, Bruce K and Arslan, Alan A and Austin, Melissa A and Baris, Dalsu and Barkauskas, Donald A and Bassig, Bryan A and Becker, Nikolaus and Benavente, Yolanda and Benhamou, Simone and Berg, Christine and Van Den Berg, David and Bernstein, Leslie and Bertrand, Kimberly A and Birmann, Brenda M and Black, Amanda and Boeing, Heiner and Boffetta, Paolo and Boutron-Ruault, Marie-Christine and Bracci, Paige M and Brinton, Louise and Brooks-Wilson, Angela R and Bueno-de-Mesquita, H Bas and Burdett, Laurie and Buring, Julie and Butler, Mary Ann and Cai, Qiuyin and Cancel-Tassin, Geraldine and Canzian, Federico and Carrato, Alfredo and Carreon, Tania and Carta, Angela and Chan, John K C and Chang, Ellen T and Chang, Gee-Chen and Chang, I-Shou and Chang, Jiang and Chang-Claude, Jenny and Chen, Chien-Jen and Chen, Chih-Yi and Chen, Chu and Chen, Chung-Hsing and Chen, Constance and Chen, Hongyan and Chen, Kexin and Chen, Kuan-Yu and Chen, Kun-Chieh and Chen, Ying and Chen, Ying-Hsiang and Chen, Yi-Song and Chen, Yuh-Min and Chien, Li-Hsin and Chirlaque, María-Dolores and Choi, Jin Eun and Choi, Yi Young and Chow, Wong-Ho and Chung, Charles C and Clavel, Jacqueline and Clavel-Chapelon, Françoise and Cocco, Pierluigi and Colt, Joanne S and Comperat, Eva and Conde, Lucia and Connors, Joseph M and Conti, David and Cortessis, Victoria K and Cotterchio, Michelle and Cozen, Wendy and Crouch, Simon and Crous-Bou, Marta and Cussenot, Olivier and Davis, Faith G and ...
Journal of the National Cancer Institute, ISSN 0027-8874, 12/2015, Volume 107, Issue 12, p. djv279
Journal Article
Journal Article
Tumor Biology, ISSN 1010-4283, 03/2015, Volume 36, Issue 3, pp. 1477 - 1486
Journal Article