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Nature cell biology, ISSN 1476-4679, 07/2018, Volume 20, Issue 8, pp. 954 - 965
.... 3Genome Integrity, Immunity and Cancer Unit, Department of Immunology, Department of Genomes and Genetics, Institut Pasteur, Paris, France. 4Division of Oncogenomics... 
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Osteosarcoma - drug therapy | Mad2 Proteins - metabolism | Humans | Multiprotein Complexes | Ovarian Neoplasms - pathology | Bone Neoplasms - pathology | DNA Breaks, Double-Stranded | Bone Neoplasms - metabolism | Breast Neoplasms - metabolism | Dose-Response Relationship, Drug | Ovarian Neoplasms - genetics | Telomere-Binding Proteins - genetics | DNA End-Joining Repair | HEK293 Cells | Female | Bone Neoplasms - genetics | Ovarian Neoplasms - metabolism | Bone Neoplasms - drug therapy | BRCA1 Protein - deficiency | Telomere-Binding Proteins - metabolism | Ovarian Neoplasms - drug therapy | Osteosarcoma - metabolism | DNA-Binding Proteins | Tumor Suppressor p53-Binding Protein 1 - metabolism | Recombinational DNA Repair | Tumor Suppressor p53-Binding Protein 1 - genetics | Cisplatin - pharmacology | Breast Neoplasms - drug therapy | Proteins - genetics | Xenograft Model Antitumor Assays | BRCA1 Protein - genetics | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Breast Neoplasms - genetics | Proteins - metabolism | Breast Neoplasms - pathology | Mad2 Proteins - genetics | Cell Line, Tumor | Mice | Osteosarcoma - genetics | Cell Cycle Proteins | Osteosarcoma - pathology | Care and treatment | DNA | Cancer cells | Breast cancer | Genetic aspects | Research | Gene expression | Single-stranded DNA | DNA damage | Homologous recombination | Poly(ADP-ribose) | Homology | Genomes | Inactivation | Proteins | Ribose | Null cells | Deoxyribonucleic acid--DNA | BRCA2 protein | CRISPR | Deactivation | BRCA1 protein | Poly(ADP-ribose) polymerase | Adenosine diphosphate | Oligosaccharides | Double-strand break repair | Screens | Cisplatin | Inhibitors | Prostate | Viability | Tumors | Index Medicus | Telomere-Binding Proteins / metabolism | Osteosarcoma / genetics | Telomere-Binding Proteins / genetics | BRCA1 Protein / genetics | Cellular Biology | Genetics | Proteins / genetics | Osteosarcoma / drug therapy | Ovarian Neoplasms / genetics | Mad2 Proteins / genetics | Proteins / metabolism | Breast Neoplasms / drug therapy | Breast Neoplasms / metabolism | Tumor Suppressor p53-Binding Protein 1 / genetics | BRCA1 Protein / deficiency | Ovarian Neoplasms / metabolism | Mad2 Proteins / metabolism | Breast Neoplasms / pathology | Bone Neoplasms / genetics | Ovarian Neoplasms / pathology | Bone Neoplasms / pathology | Life Sciences | Bone Neoplasms / drug therapy | Ovarian Neoplasms / drug therapy | Osteosarcoma / metabolism | Biochemistry, Molecular Biology | Breast Neoplasms / genetics | Drug Resistance, Neoplasm / genetics | Osteosarcoma / pathology | Bone Neoplasms / metabolism | Poly(ADP-ribose) Polymerase Inhibitors / pharmacology | Cisplatin / pharmacology | Molecular biology | Tumor Suppressor p53-Binding Protein 1 / metabolism | Cancer
Journal Article
Oncogene, ISSN 0950-9232, 10/2011, Volume 30, Issue 41, pp. 4261 - 4274
In the presence of sustained DNA damage occurring in S-phase or G2, normal cells arrest before mitosis and eventually become senescent. The checkpoint kinases... 
cyclin B1 | ATM | Chk2 | G2-M checkpoint | cell cycle | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Protein Kinases - metabolism | G2 Phase Cell Cycle Checkpoints - physiology | Phosphorylation | Protein Kinases - genetics | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Immunoblotting | Male | Cyclin B1 - metabolism | Pyrones - pharmacology | Tumor Suppressor Protein p53 - genetics | Cell Cycle Proteins - antagonists & inhibitors | DNA-Binding Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | G2 Phase Cell Cycle Checkpoints - drug effects | RNA Interference | Tumor Suppressor Proteins - genetics | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Antineoplastic Agents - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Tumor Suppressor Proteins - metabolism | DNA-Binding Proteins - antagonists & inhibitors | HCT116 Cells | Cell Cycle Proteins - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Cyclin B1 - genetics | Morpholines - pharmacology | Signal Transduction - genetics | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Piperazines - pharmacology | G2 Phase Cell Cycle Checkpoints - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Checkpoint Kinase 2 | Bleomycin - pharmacology | Checkpoint Kinase 1 | Signal Transduction - physiology | DNA Damage | HeLa Cells | Cell division | Oxidative stress | Signal transduction | DNA damage | Cyclin-dependent kinases | Cell cycle | CHK2 protein | Epithelial cells | Mitosis | CHK1 protein | G2 phase | Genotoxicity | Osteosarcoma cells | p53 protein | Cyclin-dependent kinase | Chemotherapy | Fibroblasts | Cancer | Index Medicus | Life Sciences | Biochemistry, Molecular Biology
Journal Article
Nature medicine, ISSN 1546-170X, 01/2018, Volume 24, Issue 2, pp. 176 - 185
Journal Article
by Sampson, Joshua N and Wheeler, William A and Yeager, Meredith and Panagiotou, Orestis and Wang, Zhaoming and Berndt, Sonja I and Lan, Qing and Abnet, Christian C and Amundadottir, Laufey T and Figueroa, Jonine D and Landi, Maria Teresa and Mirabello, Lisa and Savage, Sharon A and Taylor, Philip R and Vivo, Immaculata De and McGlynn, Katherine A and Purdue, Mark P and Rajaraman, Preetha and Adami, Hans-Olov and Ahlbom, Anders and Albanes, Demetrius and Amary, Maria Fernanda and An, She-Juan and Andersson, Ulrika and Aniole, Gerald and Anulis, Irene L and Angelucci, Emanuele and Ansell, Stephen M and Arici, Cecilia and Armstrong, Bruce K and Arslan, Alan A and Austin, Melissa A and Baris, Dalsu and Barkauskas, Donald A and Bassig, Bryan A and Becker, Nikolaus and Benavente, Yolanda and Benhamou, Simone and Berg, Christine and Van Den Berg, David and Bernstein, Leslie and Bertrand, Kimberly A and Birmann, Brenda M and Black, Amanda and Boeing, Heiner and Boffetta, Paolo and Boutron-Ruault, Marie-Christine and Bracci, Paige M and Brinton, Louise and Brooks-Wilson, Angela R and Bueno-de-Mesquita, H Bas and Burdett, Laurie and Buring, Julie and Butler, Mary Ann and Cai, Qiuyin and Cancel-Tassin, Geraldine and Canzian, Federico and Carrato, Alfredo and Carreon, Tania and Carta, Angela and Chan, John K C and Chang, Ellen T and Chang, Gee-Chen and Chang, I-Shou and Chang, Jiang and Chang-Claude, Jenny and Chen, Chien-Jen and Chen, Chih-Yi and Chen, Chu and Chen, Chung-Hsing and Chen, Constance and Chen, Hongyan and Chen, Kexin and Chen, Kuan-Yu and Chen, Kun-Chieh and Chen, Ying and Chen, Ying-Hsiang and Chen, Yi-Song and Chen, Yuh-Min and Chien, Li-Hsin and Chirlaque, María-Dolores and Choi, Jin Eun and Choi, Yi Young and Chow, Wong-Ho and Chung, Charles C and Clavel, Jacqueline and Clavel-Chapelon, Françoise and Cocco, Pierluigi and Colt, Joanne S and Comperat, Eva and Conde, Lucia and Connors, Joseph M and Conti, David and Cortessis, Victoria K and Cotterchio, Michelle and Cozen, Wendy and Crouch, Simon and Crous-Bou, Marta and Cussenot, Olivier and Davis, Faith G and ...
JNCI : Journal of the National Cancer Institute, ISSN 0027-8874, 12/2015, Volume 107, Issue 12, pp. djv279 - djv279
Journal Article
Bone (New York, N.Y.), ISSN 8756-3282, 09/2017, Volume 102, pp. 69 - 79
Journal Article
Nature genetics, ISSN 1546-1718, 05/2015, Volume 47, Issue 6, pp. 615 - 624
Journal Article