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Clinical Genetics, ISSN 0009-9163, 10/2014, Volume 86, Issue 4, pp. 326 - 334
Journal Article
Cell Reports, ISSN 2211-1247, 07/2014, Volume 8, Issue 2, pp. 327 - 337
Although transcriptome analysis can uncover the molecular changes that occur during induced reprogramming, the functional requirements for a given factor... 
SOMATIC-CELLS | MIR-302 | BARRIER | HUMAN FIBROBLASTS | TARGETS | PLURIPOTENCY | GENERATION | INDUCTION | MICRORNAS | EXPRESSION | CELL BIOLOGY | Embryonic Stem Cells - metabolism | NF-E2 Transcription Factor, p45 Subunit - metabolism | Embryonic Stem Cells - cytology | Membrane Glycoproteins - metabolism | Protein Disulfide-Isomerases - metabolism | Homeodomain Proteins - metabolism | Transcriptome | Otx Transcription Factors - metabolism | Neoplasm Proteins - metabolism | Inositol 1,4,5-Trisphosphate Receptors - metabolism | Otx Transcription Factors - genetics | Tumor Suppressor Proteins - genetics | Trans-Activators - genetics | Induced Pluripotent Stem Cells - cytology | Neoplasm Proteins - genetics | Cellular Reprogramming - genetics | Induced Pluripotent Stem Cells - metabolism | NF-E2 Transcription Factor, p45 Subunit - genetics | Hepatocyte Nuclear Factor 4 - metabolism | Tumor Suppressor Proteins - metabolism | Chromosomal Proteins, Non-Histone - metabolism | Signal Transduction | Epidermal Growth Factor - genetics | Cells, Cultured | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Suppressor of Cytokine Signaling Proteins - genetics | Epidermal Growth Factor - metabolism | Hepatocyte Nuclear Factor 4 - genetics | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Chromosomal Proteins, Non-Histone - genetics | Membrane Glycoproteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Protein Disulfide-Isomerases - genetics | Transcription Factors, TFII - genetics | Animals | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Transcription Factors, TFII - metabolism | Trans-Activators - metabolism | Mice | Suppressor of Cytokine Signaling Proteins - metabolism | Genome | Inositol 1,4,5-Trisphosphate Receptors - genetics | Index Medicus
Journal Article
Development, ISSN 0950-1991, 11/2003, Volume 130, Issue 21, pp. 5155 - 5167
Several eye-field transcription factors (EFTFs) are expressed in the anterior region of the vertebrate neural plate and are essential for eye formation. The... 
Noggin | Optx2 | Xenopus laevis | Eye field specification | Pax6 | Rx1 | ET | Lhx2 | Tll | Neural patterning | Six3 | Transcription factor cocktails | Ectopic eye formation | Otx2 | Genetic network | ANTERIOR NEUROECTODERM | ECTOPIC EYES | noggin | CELL-PROLIFERATION | DEVELOPMENTAL BIOLOGY | genetic network | neural patterning | eye field specification | ectopic eye formation | RETINAL DEVELOPMENT | transcription factor cocktails | BRAIN-DEVELOPMENT | XENOPUS HOMOLOG | T-BOX GENES | SINE OCULIS GENE | DROSOPHILA | HOMEOBOX GENE | Drosophila melanogaster - embryology | Xenopus Proteins - genetics | Xenopus laevis - anatomy & histology | Homeodomain Proteins - metabolism | Humans | Otx Transcription Factors | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | DNA-Binding Proteins - metabolism | Morphogenesis | Eye - embryology | In Situ Hybridization | Gene Expression Regulation, Developmental | Body Patterning | Trans-Activators - genetics | Xenopus laevis - genetics | Eye Proteins - genetics | Drosophila melanogaster - anatomy & histology | Repressor Proteins - metabolism | Carrier Proteins | Eye - metabolism | Xenopus laevis - embryology | Paired Box Transcription Factors | Repressor Proteins - genetics | PAX6 Transcription Factor | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Animals | Proteins - metabolism | Eye Proteins - metabolism | Xenopus laevis - metabolism | LIM-Homeodomain Proteins | Trans-Activators - metabolism | Xenopus Proteins - metabolism | Drosophila Proteins - genetics | Index Medicus
Journal Article
Journal Article
Development, ISSN 0950-1991, 03/2010, Volume 137, Issue 5, pp. 725 - 734
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1761, Volume 289, Issue 18, pp. 12908 - 12921
Journal Article
Genes and Development, ISSN 0890-9369, 10/2015, Volume 29, Issue 20, pp. 2108 - 2122
Journal Article
Scientific Reports, ISSN 2045-2322, 07/2015, Volume 5, Issue 1, pp. 12622 - 12622
Degeneration of midbrain dopaminergic (DA) neurons is a key pathological event of Parkinson's disease (PD). Limited adult dopaminergic neurogenesis has led to... 
DEFINED FACTORS | FUNCTIONAL-NEURONS | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | RESTRICTED PROGENITORS | SELF-RENEWAL | DIFFERENTIATION | FATE | MIDBRAIN | PARKINSONS-DISEASE | NEURON DEVELOPMENT | Hepatocyte Nuclear Factor 3-beta - genetics | LIM-Homeodomain Proteins - metabolism | Otx Transcription Factors - metabolism | Male | MPTP Poisoning - therapy | Neural Stem Cells - cytology | Dopaminergic Neurons - cytology | SOXB1 Transcription Factors - metabolism | POU Domain Factors - genetics | SOXB1 Transcription Factors - genetics | Otx Transcription Factors - genetics | Dopaminergic Neurons - metabolism | Nestin - genetics | Serine Endopeptidases - genetics | Cell Differentiation | Induced Pluripotent Stem Cells - cytology | Real-Time Polymerase Chain Reaction | Action Potentials - drug effects | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | POU Domain Factors - metabolism | Hepatocyte Nuclear Factor 3-beta - metabolism | Induced Pluripotent Stem Cells - transplantation | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | Doxorubicin - toxicity | Nerve Tissue Proteins - metabolism | Nestin - metabolism | Transcription Factors - metabolism | Cell Lineage | LIM-Homeodomain Proteins - genetics | Patch-Clamp Techniques | Animals | Cell Proliferation - drug effects | Fibroblasts - cytology | Mice | Proto-Oncogene Proteins c-myc - genetics | Serine Endopeptidases - metabolism | Neural Stem Cells - metabolism | Dopamine | Parkinson's disease | Mesencephalon | Neurodegenerative diseases | Transplantation | Motor task performance | Neurogenesis | Neurodegeneration | Rodents | Neostriatum | Fibroblasts | Neural stem cells | Otx2 protein | MPTP | Movement disorders | Dopamine receptors | Index Medicus
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2011, Volume 31, Issue 46, pp. 16792 - 16807
Journal Article
CELL, ISSN 0092-8674, 11/2003, Volume 115, Issue 5, pp. 615 - 627
In chordates, formation of neural tissue from ectodermal cells requires an induction. The molecular nature of the inducer remains controversial in vertebrates.... 
NERVOUS-SYSTEM | NOTOCHORD | CHORDATE CIONA-INTESTINALIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | XENOPUS EMBRYOS | FIBROBLAST-GROWTH-FACTOR | INDUCTION | SPECIFICATION | HOMEOBOX GENE | CELL FATE | EXPRESSION | CELL BIOLOGY | Embryo, Nonmammalian - cytology | Homeodomain Proteins - metabolism | Nervous System - metabolism | Embryo, Nonmammalian - metabolism | Fibroblast Growth Factors - genetics | Embryo, Nonmammalian - embryology | Otx Transcription Factors | Ciona intestinalis - cytology | DNA-Binding Proteins - metabolism | Models, Animal | Nervous System - embryology | Proto-Oncogene Proteins c-ets | Ciona intestinalis - embryology | Proto-Oncogene Proteins - metabolism | Nervous System - cytology | Embryonic Induction - physiology | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | Binding Sites - genetics | Fibroblast Growth Factors - deficiency | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Transcription Factors - metabolism | Ciona intestinalis - metabolism | Animals | Biomarkers | Erythroid-Specific DNA-Binding Factors | Proto-Oncogene Protein c-ets-1 | Fibroblast Growth Factor 9 | Embryology | Research | Developmental neurology | Genetic transcription | Chordata | Analysis | GATA protein | Ets protein | Otx gene | Index Medicus | Life Sciences | Development Biology
Journal Article