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Pharmacological Research, ISSN 1043-6618, 12/2014, Volume 90, pp. 25 - 35
Journal Article
Circulation Research, ISSN 0009-7330, 10/2004, Volume 95, Issue 7, pp. 726 - 733
Altered gap junction coupling of cardiac myocytes during ischemia may contribute to development of lethal arrhythmias. The phosphoprotein connexin 43 (Cx43) is... 
Ischemia | Gap junctions | Glycolysis | Okadaic acid | Protein phosphatases | Connexin43 | Protein phosphorylation | AMP kinase | gap junctions | PROTEIN-KINASE-C | CARDIAC & CARDIOVASCULAR SYSTEMS | connexin43 | PHOSPHORYLATION | GAP JUNCTIONAL COMMUNICATION | glycolysis | CARDIAC MYOCYTES | ACTIN GENE | protein phosphorylation | okadaic acid | ischemia | IN-VITRO | INTERCELLULAR COMMUNICATION | PERIPHERAL VASCULAR DISEASE | JUN KINASE | protein phosphatases | RAT VENTRICULAR MYOCYTES | HEMATOLOGY | ADRENERGIC REGULATION | Okadaic Acid - pharmacology | Tetradecanoylphorbol Acetate - pharmacology | Maleimides - pharmacology | Recombinant Fusion Proteins - physiology | Myocardial Contraction - drug effects | Brefeldin A - pharmacology | Phenanthridines - pharmacology | Antimycin A - pharmacology | Aminoimidazole Carboxamide - pharmacology | Cell Hypoxia | Ribonucleotides - pharmacology | Alkaloids | Protein Processing, Post-Translational - drug effects | Adenosine Triphosphate - metabolism | Deoxyglucose - pharmacology | Tacrolimus - pharmacology | Indoles - pharmacology | Flavonoids - pharmacology | Potassium Cyanide - pharmacology | JNK Mitogen-Activated Protein Kinases - genetics | Phosphorylation - drug effects | Ouabain - pharmacology | Cells, Cultured - drug effects | Connexin 43 - metabolism | Rats | Imidazoles - pharmacology | Cycloheximide - pharmacology | Pyrroles - pharmacology | Animals | Myocytes, Cardiac - drug effects | Aminoimidazole Carboxamide - analogs & derivatives | Benzophenanthridines | JNK Mitogen-Activated Protein Kinases - physiology | Myocytes, Cardiac - metabolism | Cells, Cultured - metabolism | Pyridines - pharmacology | Carbazoles - pharmacology | Staurosporine - pharmacology | Index Medicus
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2004, Volume 24, Issue 26, pp. 5922 - 5930
We used a model system in which dopaminergic (DA) neurons from embryonic rat mesencephalon undergo spontaneous and selective degeneration as they develop in... 
Excitability | GDNF | Sodium | Channel | Trophic | Dopaminergic | TYROSINE-HYDROXYLASE | POTASSIUM CHANNELS | NEUROTROPHIC FACTOR | channel | trophic | NEUROSCIENCES | sodium | CYCLIC-AMP | excitability | CALCIUM-CHANNELS | SIGNALING PATHWAY | MEMBRANE-PROPERTIES | CENTRAL-NERVOUS-SYSTEM | dopaminergic | SMALL-CONDUCTANCE | PARKINSONS-DISEASE | Mesencephalon - cytology | Sodium-Potassium-Exchanging ATPase - physiology | Rats, Wistar | Apoptosis - drug effects | gamma-Aminobutyric Acid - metabolism | Cells, Cultured - cytology | Neurons - cytology | Sodium Channels - physiology | Apamin - pharmacology | Nerve Growth Factors - pharmacology | Neuroprotective Agents - pharmacology | Glial Cell Line-Derived Neurotrophic Factor | Ion Transport - drug effects | Neurons - metabolism | Aspirin - pharmacology | Tetrodotoxin - pharmacology | Neurons - drug effects | Dopamine - metabolism | Ouabain - pharmacology | Potassium Channel Blockers - pharmacology | Sodium - pharmacology | Cells, Cultured - drug effects | Nerve Tissue Proteins - physiology | Nifedipine - pharmacology | Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors | Biological Transport, Active - drug effects | Rats | Sodium Channel Blockers - pharmacology | Sodium Channels - drug effects | Calcium Channel Blockers - pharmacology | Nerve Tissue Proteins - drug effects | Veratridine - pharmacology | Scorpion Venoms - pharmacology | Animals | Calcium Channels, T-Type - drug effects | Serotonin - metabolism | Calcium Channel Agonists - pharmacology | Cells, Cultured - metabolism | Potassium Channels, Calcium-Activated - antagonists & inhibitors | Ion Channel Gating | Sodium - physiology | Index Medicus | Tetrodotoxin | Neuroprotective Agents | Veratridine | Mesencephalon | Neurons and Cognition | Ouabain | Calcium Channel Agonists | Calcium Channels, T-Type | Potassium Channels, Calcium-Activated | Life Sciences | Biological Transport, Active | Sodium-Potassium-Exchanging ATPase | Ion Transport | Potassium Channel Blockers | gamma-Aminobutyric Acid | Aspirin | Apamin | Dopamine | Serotonin | Neurons | Sodium Channels | Cells, Cultured | Nerve Tissue Proteins | Nifedipine | Scorpion Venoms | Calcium Channel Blockers | Nerve Growth Factors | Sodium Channel Blockers | Apoptosis
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 06/2017, Volume 232, Issue 6, pp. 1489 - 1500
Studies were conducted to examine the insulin response in ocular nonpigmented ciliary epithelium. Insulin elicited a pronounced short term increase in... 
DIABETES-MELLITUS | SKELETAL-MUSCLE | OPEN-ANGLE GLAUCOMA | PHYSIOLOGY | ALPHA-SUBUNIT | PORCINE LENS EPITHELIUM | AQUEOUS-HUMOR FLOW | NA+/K+-ATPASE | GENE-EXPRESSION | INTRAOCULAR-PRESSURE | PLASMA-MEMBRANE | CELL BIOLOGY | Nitriles - pharmacology | Heterocyclic Compounds, 3-Ring - pharmacology | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Ciliary Body - metabolism | Time Factors | src-Family Kinases - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Rubidium - metabolism | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Ouabain - pharmacology | Epithelium - drug effects | Insulin - pharmacology | Butadienes - pharmacology | Pigmentation - drug effects | Epithelium - metabolism | Morpholines - pharmacology | Imidazoles - pharmacology | Pyrimidines - pharmacology | Enzyme Activation - drug effects | Sodium-Potassium-Exchanging ATPase - metabolism | Insulin - metabolism | Animals | Signal Transduction - drug effects | Models, Biological | Ciliary Body - drug effects | Pyridines - pharmacology | Sus scrofa | Epithelium | Insulin | Adenosine triphosphatase | Ouabain | Secretion | Change detection | Extracellular signal-regulated kinase | AKT protein | Activation | Exposure | Rubidium | Src protein | Tissues | Na+/K+-exchanging ATPase | 1-Phosphatidylinositol 3-kinase | Hydrolysis | Signal transduction | Inhibitors | Pathways | Potassium | Activation analysis | Index Medicus
Journal Article
The Journal of Sexual Medicine, ISSN 1743-6095, 05/2008, Volume 5, Issue 5, pp. 1114 - 1125
In addition to nitric oxide (NO), it is thought that an endothelium-derived hyperpolarizing factor (EDHF) plays an important role in the relaxation of penile... 
Acetylcholine | CNP | Human Penile Arteries | EDHF | Endothelium | endothelium | CA2+-ACTIVATED K+ CHANNELS | INDUCED VASODILATION | human penile arteries | NONADRENERGIC NONCHOLINERGIC NEUROTRANSMISSION | MEDIATED RELAXATION | SMOOTH-MUSCLE | CORPUS CAVERNOSUM | ENDOTHELIUM-DEPENDENT RELAXATIONS | NITRIC-OXIDE | UROLOGY & NEPHROLOGY | acetylcholine | ERECTILE DYSFUNCTION | GUANYLYL CYCLASE-B | Natriuretic Agents - pharmacology | Humans | Middle Aged | Male | Apamin - pharmacology | Large-Conductance Calcium-Activated Potassium Channel alpha Subunits - drug effects | Arteries - physiology | Charybdotoxin - pharmacology | Natriuretic Peptide, C-Type - drug effects | Vascular Resistance - drug effects | Adult | Natriuretic Peptide, C-Type - pharmacology | Penis - blood supply | Muscle, Smooth, Vascular - physiology | Ouabain - pharmacology | Membrane Potentials - drug effects | Vasodilator Agents - pharmacology | Acetylcholine - pharmacology | Chlorides - pharmacology | Enzyme Inhibitors - pharmacology | Large-Conductance Calcium-Activated Potassium Channel alpha Subunits - metabolism | Arteries - drug effects | Membrane Potentials - physiology | Indomethacin - pharmacology | Barium Compounds - pharmacology | Cyclooxygenase Inhibitors - pharmacology | Peptides - pharmacology | Neurotoxins - pharmacology | Nitroarginine - pharmacology | Natriuretic Peptide, C-Type - metabolism | Adolescent | Blood vessels | Endothelium-derived relaxing factors | Dilatation | Arteries | Natriuretic peptides | Index Medicus
Journal Article
Life Sciences, ISSN 0024-3205, 10/2012, Volume 91, Issue 11-12, pp. 402 - 408
Journal Article
Hypertension, ISSN 0194-911X, 03/2006, Volume 47, Issue 3, Part 2 Suppl, pp. 596 - 602
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2015, Volume 35, Issue 35, pp. 12172 - 12187
Spreading depolarizations (SDs) are waves of sustained neuronal and glial depolarization that propagate massive disruptions of ion gradients through the brain.... 
Two-photon microscopy | Neuronal swelling | Cl-cotransporters | Cotransporters | Spreading depression | Dendritic beading | INTRACELLULAR CHLORIDE | MONOCARBOXYLATE TRANSPORTER | DEPRESSION-LIKE DEPOLARIZATION | BRAIN CORTEX | cotransporters | ANOXIC DEPOLARIZATION | BLOOD-FLOW | NEUROSCIENCES | spreading depression | neuronal swelling | IN-VIVO | two-photon microscopy | EXTRACELLULAR PH CHANGES | dendritic beading | RAT HIPPOCAMPAL SLICES | CEREBRAL-ISCHEMIA | Chlorates - pharmacology | Pyramidal Cells - metabolism | CA1 Region, Hippocampal - cytology | Sodium Potassium Chloride Symporter Inhibitors - pharmacology | Male | Cortical Spreading Depression - physiology | Adenosine Triphosphate - pharmacology | Excitatory Postsynaptic Potentials - physiology | Dendrites - physiology | Female | Pyramidal Cells - drug effects | Receptors, Chemokine - genetics | Thiazolidines - pharmacology | Ouabain - pharmacology | Pyramidal Cells - cytology | Dendrites - metabolism | CA1 Region, Hippocampal - physiology | 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid - pharmacology | Receptors, Chemokine - metabolism | Mice, Transgenic | Symporters - metabolism | Cortical Spreading Depression - drug effects | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | Symporters - genetics | Mice | Furosemide - pharmacology | In Vitro Techniques | CX3C Chemokine Receptor 1 | Index Medicus
Journal Article
Neuropharmacology, ISSN 0028-3908, 10/2013, Volume 73, pp. 327 - 336
Journal Article
The Journal of Physiology, ISSN 0022-3751, 05/2004, Volume 556, Issue 3, pp. 875 - 886
A role for myoendothelial gap junctions (MEGJs) has been proposed in the action of the vasodilator endothelium-derived hyperpolarizing factor (EDHF). EDHF... 
SMOOTH-MUSCLE | PHYSIOLOGY | MESENTERIC-ARTERIES | POTASSIUM CHANNELS | ENDOTHELIUM-DEPENDENT HYPERPOLARIZATION | HYPERTENSIVE RATS | GUINEA-PIG | CONNEXIN EXPRESSION | CORONARY-ARTERIES | SMALL-CONDUCTANCE | EDHF-TYPE RELAXATIONS | Catalase - pharmacology | Endothelium, Vascular - cytology | Immunohistochemistry | Rats, Inbred WKY | Male | Peptide Fragments - pharmacology | Apamin - pharmacology | Endothelium, Vascular - physiology | 8,11,14-Eicosatrienoic Acid - analogs & derivatives | Phenylephrine - pharmacology | Arteries - physiology | Charybdotoxin - pharmacology | Vasodilation - physiology | 8,11,14-Eicosatrienoic Acid - pharmacology | Connexins - pharmacology | Myocytes, Smooth Muscle - drug effects | Hydroxocobalamin - pharmacology | Ouabain - pharmacology | Connexins - chemistry | Pyrazoles - pharmacology | Membrane Potentials - drug effects | NG-Nitroarginine Methyl Ester - pharmacology | Acetylcholine - pharmacology | Biological Factors - physiology | Myocytes, Smooth Muscle - physiology | Rats | Arteries - drug effects | Barium - pharmacology | Femoral Artery - drug effects | Microscopy, Electron | Indomethacin - pharmacology | Connexin 26 | Gap Junctions - ultrastructure | Patch-Clamp Techniques | Animals | Gap Junctions - physiology | Models, Biological | Femoral Artery - physiology | Vasodilation - drug effects | In Vitro Techniques | Index Medicus | Research Papers
Journal Article
Circulation, ISSN 0009-7322, 01/2005, Volume 111, Issue 2, pp. 198 - 203
Background - The large-conductance Ca2+- activated K+ (BKCa) channel in the cardiac inner mitochondrial membrane (mitoK(Ca) channel) has been shown to protect... 
Cyclic AMP-dependent protein kinases | Mitochondria | Potassium channels, calcium-activated | Myocytes | SENSITIVE POTASSIUM CHANNELS | CARDIAC & CARDIOVASCULAR SYSTEMS | cyclic AMP-dependent protein kinases | mitochondria | MEMBRANE | DEATH | METABOLIC INHIBITION | CA2+ OVERLOAD | DIAZOXIDE | myocytes | HEART | DEPOLARIZATION | PATHWAY | potassium channels, calcium-activated | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Potassium - metabolism | Fluorescent Dyes - pharmacokinetics | Heterocyclic Compounds, 3-Ring | Carbocyanines - pharmacokinetics | Hydroxy Acids - pharmacology | Diazoxide - pharmacology | Mitochondria, Heart - metabolism | Tetradecanoylphorbol Acetate - pharmacology | Mitochondria, Heart - drug effects | Heart Ventricles | Cell Death | Indoles - pharmacology | Ion Transport - drug effects | Ouabain - pharmacology | Membrane Potentials - drug effects | Potassium Channels, Calcium-Activated - physiology | Second Messenger Systems - drug effects | Guinea Pigs | Colforsin - pharmacology | Decanoic Acids - pharmacology | 8-Bromo Cyclic Adenosine Monophosphate - pharmacology | Benzimidazoles - pharmacokinetics | Membrane Potentials - physiology | Cyclic AMP-Dependent Protein Kinases - physiology | Animals | Myocytes, Cardiac - drug effects | Myocytes, Cardiac - physiology | Potassium Channels, Calcium-Activated - drug effects | Benzimidazoles - pharmacology | Second Messenger Systems - physiology | Intracellular Membranes - drug effects | Ion Transport - physiology | Intracellular Membranes - metabolism | Index Medicus | Abridged Index Medicus
Journal Article