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1. Full Text Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest
by Nielsen, Niklas and Wetterslev, Jørn and Cronberg, Tobias and Erlinge, David and Gasche, Yvan and Hassager, Christian and Horn, Janneke and Hovdenes, Jan and Kjaergaard, Jesper and Kuiper, Michael and Pellis, Tommaso and Stammet, Pascal and Wanscher, Michael and Wise, Matt P and Åneman, Anders and Al-Subaie, Nawaf and Boesgaard, Søren and Bro-Jeppesen, John and Brunetti, Iole and Bugge, Jan Frederik and Hingston, Christopher D and Juffermans, Nicole P and Koopmans, Matty and Køber, Lars and Langørgen, Jørund and Lilja, Gisela and Møller, Jacob Eifer and Rundgren, Malin and Rylander, Christian and Smid, Ondrej and Werer, Christophe and Winkel, Per and Friberg, Hans and TTM Trial Investigators
The New England Journal of Medicine, ISSN 0028-4793, 12/2013, Volume 369, Issue 23, pp. 2197 - 2206
In this trial, 950 patients who had been resuscitated from out-of-hospital cardiac arrest were randomly assigned to targeted temperature management at either... 
Cardiopulmonary Resuscitation - methods | Follow-Up Studies | Out-of-Hospital Cardiac Arrest - complications | Humans | Middle Aged | Kaplan-Meier Estimate | Male | Out-of-Hospital Cardiac Arrest - mortality | Models, Statistical | Body Temperature | Withholding Treatment | Out-of-Hospital Cardiac Arrest - therapy | Treatment Failure | Hypothermia, Induced | Adult | Female | Aged | Unconsciousness - etiology | Coma | Heart | Intervention | Intensive care | Mortality | Body temperature | Critical care | Rhythm | Patients | Cardiopulmonary resuscitation--CPR | Fever | Temperature effects | Anesthesia | Hypothermia
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2. Full Text Targeted Temperature Management at 33 degrees C versus 36 degrees C after Cardiac Arrest
by Nielsen, N and Wettersley, J and Cronberg, T and Erlinge, D and Gasche, Y and Hassager, C and Horn, J and Hovdenes, J and Kjaergaard, J and Kuiper, M and Pellis, T and Stammet, P and Wanscher, M and Wise, MP and Aneman, A and Al-Subaie, N and Boesgaard, S and Bro-Jeppesen, J and Brunetti, I and Bugge, JF and Hingston, CD and Juffermans, NP and Koopmans, M and Kober, L and Langorgen, J and Lilja, G and Moller, JE and Rundgren, M and Rylander, C and Smid, O and Werer, C and Winkel, P and Friberg, H and TTM Trial Investigators and Anestesiologi och intensivvård and Kardiologi and Lund University and Anesthesiology and Intensive Care and Neurologi, Lund and Cardiology and Lunds universitet and Neurology, Lund
NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 12/2013, Volume 369, Issue 23, pp. 2197 - 2206
BackgroundUnconscious survivors of out-of-hospital cardiac arrest have a high risk of death or poor neurologic function. Therapeutic hypothermia is recommended... 
SURVIVAL | MEDICINE, GENERAL & INTERNAL | THERAPEUTIC HYPOTHERMIA | INCREASE | OUTCOMES | CARDIOPULMONARY-RESUSCITATION | CARE | Kardiologi | Clinical Medicine | Neurologi | Neurology | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Medicin och hälsovetenskap | Anestesi och intensivvård | Anesthesiology and Intensive Care | Klinisk medicin
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3. Full Text Early Cardiopulmonary Resuscitation in Out-of-Hospital Cardiac Arrest
by Hasselqvist-Ax, Ingela and Riva, Gabriel and Herlitz, Johan and Rosenqvist, Mårten and Hollenberg, Jacob and Nordberg, Per and Ringh, Mattias and Jonsson, Martin and Axelsson, Christer and Lindqvist, Jonny and Karlsson, Thomas and Svensson, Leif and Akademin för vård, arbetsliv och välfärd and Högskolan i Borås
The New England Journal of Medicine, ISSN 0028-4793, 06/2015, Volume 372, Issue 24, pp. 2307 - 2315
This study examined whether training in cardiopulmonary resuscitation increases the frequency of bystander CPR and the rate of survival. CPR performed before... 
SURVIVAL | SWEDEN | COUNCIL GUIDELINES | POPULATION | RATES | MEDICINE, GENERAL & INTERNAL | BASIC LIFE-SUPPORT | AUTOMATED EXTERNAL DEFIBRILLATORS | UPDATE | AMERICAN-HEART-ASSOCIATION | CARE | Telephone | Time-to-Treatment | Out-of-Hospital Cardiac Arrest - complications | Humans | Middle Aged | Male | Out-of-Hospital Cardiac Arrest - mortality | Survival Rate | Sweden - epidemiology | Cardiopulmonary Resuscitation | Out-of-Hospital Cardiac Arrest - therapy | Propensity Score | Telemedicine | Aged, 80 and over | Adult | Female | Aged | Emergency Medical Services | Usage | Care and treatment | Emergency service | Hospitals | Cardiac arrest | CPR (First aid) | Management | Patients | Heart rate | Fibrillation | Heart attacks | Emergency medical care | Ventricle | Cardiopulmonary resuscitation--CPR | Survival | Medical and Health Sciences | Människan i vården | Medicin och hälsovetenskap
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4. Full Text Mechanical Chest Compressions and Simultaneous Defibrillation vs Conventional Cardiopulmonary Resuscitation in Out-of-Hospital Cardiac Arrest: The LINC Randomized Trial
by Rubertsson, Sten and Lindgren, Erik and Smekal, David and Östlund, Ollie and Silfverstolpe, Johan and Lichtveld, Robert A and Boomars, Rene and Ahlstedt, Björn and Skoog, Gunnar and Kastberg, Robert and Halliwell, David and Box, Martyn and Herlitz, Johan and Karlsten, Rolf and Medicinska fakulteten and Anestesiologi och intensivvård and Medicinska och farmaceutiska vetenskapsområdet and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Uppsala universitet and Institutionen för kirurgiska vetenskaper and Uppsala kliniska forskningscentrum (UCR)
JAMA, ISSN 0098-7484, 01/2014, Volume 311, Issue 1, pp. 53 - 61
IMPORTANCE A strategy using mechanical chest compressions might improve the poor outcome in out-of-hospital cardiac arrest, but such a strategy has not been... 
SURVIVAL | MEDICINE, GENERAL & INTERNAL | QUALITY | VENTRICULAR-FIBRILLATION | DEVICE | LUCAS | PERFUSION-PRESSURE | BLOOD-FLOW | Cardiopulmonary Resuscitation - methods | Out-of-Hospital Cardiac Arrest - complications | Humans | Middle Aged | Electric Countershock | Male | Out-of-Hospital Cardiac Arrest - physiopathology | Young Adult | Out-of-Hospital Cardiac Arrest - therapy | Adolescent | Survival Analysis | Aged, 80 and over | Adult | Female | Aged | Emergency Medical Services | Practice Guidelines as Topic | CPR (First aid) | Research | Comparative analysis | Electric countershock | Health aspects | Patient outcomes | Medical research | Survival analysis | Heart attacks | Cardiopulmonary resuscitation--CPR | Medical and Health Sciences | Medicin och hälsovetenskap
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5. Full Text Infectious complications in out-of-hospital cardiac arrest patients in the therapeutic hypothermia era
by Mongardon, Nicolas and Perbet, Sébastien and Lemiale, Virginie and Dumas, Florence and Poupet, Hélène and Charpentier, Julien and Péne, Frédéric and Chiche, Jean-Daniel and Mira, Jean-Paul and Cariou, Alain
Critical Care Medicine, ISSN 0090-3493, 06/2011, Volume 39, Issue 6, pp. 1359 - 1364
OBJECTIVES:Infectious complications are frequently reported in critically ill patients, especially after cardiac arrest. Recent and widespread use of... 
epidemiology | infection | therapeutic hypothermia | outcome | out-of-hospital cardiac arrest | EUROPEAN-RESUSCITATION-COUNCIL | AMERICAN-HEART-ASSOCIATION | MODERATE HYPOTHERMIA | CARDIOPULMONARY-RESUSCITATION | INTERNATIONAL LIAISON COMMITTEE | TASK-FORCE | INTENSIVE-CARE-UNIT | SURVIVORS | PROMISING TREATMENT MODALITY | STROKE FOUNDATION | CRITICAL CARE MEDICINE | Length of Stay | Out-of-Hospital Cardiac Arrest - complications | Humans | Middle Aged | Male | Out-of-Hospital Cardiac Arrest - mortality | Infection - microbiology | Incidence | Out-of-Hospital Cardiac Arrest - therapy | Infection - epidemiology | Hypothermia, Induced | Critical Care | Female | Aged | Retrospective Studies | Resuscitation | Cohort Studies
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6. Full Text Neurologic Function and Health-Related Quality of Life in Patients Following Targeted Temperature Management at 33°C vs 36°C After Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial
by Cronberg, Tobias and Lilja, Gisela and Horn, Janneke and Kjaergaard, Jesper and Wise, Matt P and Pellis, Tommaso and Hovdenes, Jan and Gasche, Yvan and Åneman, Anders and Stammet, Pascal and Erlinge, David and Friberg, Hans and Hassager, Christian and Kuiper, Michael and Wanscher, Michael and Bosch, Frank and Cranshaw, Julius and Kleger, Gian-Reto and Persson, Stefan and Undén, Johan and Walden, Andrew and Winkel, Per and Wetterslev, Jørn and Nielsen, Niklas and TTM Trial Investigators and Anestesiologi och intensivvård and Kardiologi and Lund University and Anesthesiology and Intensive Care and Neurologi, Lund and Cardiology and Lunds universitet and Neurology, Lund and Anaesthesiology and Intensive Care Medicine
JAMA Neurology, ISSN 2168-6149, 06/2015, Volume 72, Issue 6, pp. 634 - 641
IMPORTANCE: Brain injury affects neurologic function and quality of life in survivors after cardiac arrest. OBJECTIVE: To compare the effects of 2 target... 
Single-Blind Method | Outcome Assessment (Health Care) | Out-of-Hospital Cardiac Arrest - complications | Humans | Middle Aged | Male | Body Temperature - physiology | Out-of-Hospital Cardiac Arrest - therapy | Cognition Disorders - etiology | Hypothermia, Induced | Quality of Life | Female | Aged | Neurologi | Clinical Medicine | Neurology | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
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7. Full Text Return to work in out-of-hospital cardiac arrest survivors: A nationwide register-based follow-up study
by Kragholm, Kristian and Wissenberg, Mads and Mortensen, Rikke Normark and Fonager, Kirsten and Jensen, Svend Eggert and Rajan, Shahzleen and Lippert, Freddy Knudsen and Christensen, Erika Frischknecht and Hansen, Poul Anders and Lang-Jensen, Torsten and Hendriksen, Ole Mazur and Kober, Lars and Gislason, Gunnar and Torp-Pedersen, Christian and Rasmussen, Bodil Steen
Circulation, ISSN 0009-7322, 2015, Volume 131, Issue 19, pp. 1682 - 1690
Background-Data on long-term function of out-of-hospital cardiac arrest survivors are sparse. We examined return to work as a proxy of preserved function... 
Heart arrest | Epidemiology | Cardiopulmonary resuscitation | STROKE | epidemiology | cardiopulmonary resuscitation | CARDIAC & CARDIOVASCULAR SYSTEMS | THERAPEUTIC HYPOTHERMIA | TRANSFER PAYMENTS | JAPAN | PERIPHERAL VASCULAR DISEASE | heart arrest | HEALTH-STATUS | LIFE | RESUSCITATION | Out-of-Hospital Cardiac Arrest - epidemiology | Follow-Up Studies | Out-of-Hospital Cardiac Arrest - complications | Humans | Middle Aged | Risk Factors | Survivors - statistics & numerical data | Proportional Hazards Models | Male | Hypoxia, Brain - etiology | Return to Work | Socioeconomic Factors | Salaries and Fringe Benefits | Young Adult | Adolescent | Denmark - epidemiology | Adult | Female | Registries | Aged | Hypoxia, Brain - epidemiology
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8. Full Text Neuron-Specific Enolase as a Predictor of Death or Poor Neurological Outcome After Out-of-Hospital Cardiac Arrest and Targeted Temperature Management at 33°C and 36°C
by Stammet, Pascal, MD and Collignon, Olivier, PhD and Hassager, Christian, MD, DMSc and Wise, Matthew P., MD, DPhil and Hovdenes, Jan, MD, PhD and Åneman, Anders, MD, PhD and Horn, Janneke, MD, PhD and Devaux, Yvan, PhD and Erlinge, David, MD, PhD and Kjaergaard, Jesper, MD, DMSc and Gasche, Yvan, MD and Wanscher, Michael, MD, PhD and Cronberg, Tobias, MD, PhD and Friberg, Hans, MD, PhD and Wetterslev, Jørn, MD, PhD and Pellis, Tommaso, MD and Kuiper, Michael, MD, PhD and Gilson, Georges, PhD and Nielsen, Niklas, MD, PhD and TTM-Trial Investigators and Anestesiologi och intensivvård and Kardiologi and Lund University and Anesthesiology and Intensive Care and Neurologi, Lund and Cardiology and Lunds universitet and Neurology, Lund
Journal of the American College of Cardiology, ISSN 0735-1097, 2015, Volume 65, Issue 19, pp. 2104 - 2114
Abstract Background Neuron-specific enolase (NSE) is a widely-used biomarker for prognostication of neurological outcome after cardiac arrest, but the... 
Cardiovascular | Internal Medicine | neuroprognostication | biomarker | cerebral performance | prognosis | Brain Ischemia - epidemiology | Temperature | Prognosis | Prospective Studies | Follow-Up Studies | Out-of-Hospital Cardiac Arrest - complications | Humans | Middle Aged | Europe - epidemiology | Male | Out-of-Hospital Cardiac Arrest - mortality | Treatment Outcome | Biomarkers - blood | Brain Ischemia - etiology | Incidence | Brain Ischemia - enzymology | Phosphopyruvate Hydratase - blood | Hypothermia, Induced - methods | Female | Out-of-Hospital Cardiac Arrest - enzymology | Anesthesia | Neurons | Analysis | Cardiac arrest | Confidence intervals | Heart attacks | Statistical analysis | Laboratories | Mortality | Brain damage | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
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9. Full Text Association of bystander and first-responder intervention with survival after out-of-hospital cardiac arrest in North Carolina, 2010-2013
by Hansen, Carolina Malta and Kragholm, Kristian and Pearson, David A and Tyson, Clark and Monk, Lisa and Myers, Brent and Nelson, Darrell and Dupre, Matthew E and Fosbøl, Emil L and Jollis, James G and Strauss, Benjamin and Anderson, Monique L and McNally, Bryan and Granger, Christopher B
JAMA - Journal of the American Medical Association, ISSN 0098-7484, 07/2015, Volume 314, Issue 3, pp. 255 - 264
IMPORTANCE Out-of-hospital cardiac arrest is associated with low survival, but early cardiopulmonary resuscitation (CPR) and defibrillation can improve... 
UNITED-STATES | MEDICINE, GENERAL & INTERNAL | PUBLIC-ACCESS DEFIBRILLATION | ASSISTED CARDIOPULMONARY-RESUSCITATION | COMMUNITY | IMPLEMENTATION | AUTOMATED EXTERNAL DEFIBRILLATORS | MULTIPLE IMPUTATION | FULLY CONDITIONAL SPECIFICATION | AMERICAN-HEART-ASSOCIATION | LAY RESCUERS | North Carolina | Cardiopulmonary Resuscitation - education | Out-of-Hospital Cardiac Arrest - complications | Humans | Middle Aged | Male | Out-of-Hospital Cardiac Arrest - mortality | Electric Countershock - trends | Young Adult | Out-of-Hospital Cardiac Arrest - therapy | Emergency Responders | Defibrillators | Cardiopulmonary Resuscitation - trends | Survival Analysis | Adult | Female | Aged | Odds Ratio | Emergency Medical Services | Care and treatment | Usage | Cardiac output | Cardiac resuscitation | Analysis | Cardiac arrest | Survival analysis | Hospitalization | Heart attacks | Cardiology | Cardiopulmonary resuscitation--CPR | Clinical outcomes
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10. Full Text Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial
by Kirkegaard, Hans and Søreide, Eldar and de Haas, Inge and Pettilä, Ville and Taccone, Fabio Silvio and Arus, Urmet and Storm, Christian and Hassager, Christian and Nielsen, Jørgen Feldbæk and Sørensen, Christina Ankjær and Ilkjær, Susanne and Jeppesen, Anni Nørgaard and Grejs, Anders Morten and Duez, Christophe Henri Valdemar and Hjort, Jakob and Larsen, Alf Inge and Toome, Valdo and Tiainen, Marjaana and Hästbacka, Johanna and Laitio, Timo and Skrifvars, Markus B
JAMA, ISSN 0098-7484, 07/2017, Volume 318, Issue 4, pp. 341 - 350
IMPORTANCE: International resuscitation guidelines recommend targeted temperature management (TTM) at 33°C to 36°C in unconscious patients with out-of-hospital... 
MEDICINE, GENERAL & INTERNAL | ADMISSION | THERAPEUTIC HYPOTHERMIA | CARDIOPULMONARY | MILD HYPOTHERMIA | PROTOCOL | COMATOSE SURVIVORS | INDUCTION | DURATION | CARE | RESUSCITATION | Hypothermia, Induced - adverse effects | Cardiopulmonary Resuscitation - methods | Out-of-Hospital Cardiac Arrest - complications | Humans | Middle Aged | Male | Out-of-Hospital Cardiac Arrest - mortality | Body Temperature | Out-of-Hospital Cardiac Arrest - therapy | Time Factors | Female | Aged | Brain Diseases - etiology | Unconsciousness - etiology | Clinical trials | Outcome and process assessment (Health Care) | Care and treatment | Usage | Analysis | Cardiac arrest | Heart | Intensive care | Temperature | Statistical analysis | Body temperature | Mortality | Management | Patients | Clinical outcomes | Neurology | Intensive care units | Randomization | Morality | Hospitals | Temperature effects | Design standards | Adults | Heart diseases | Resuscitation | Caring for the Critically Ill Patient | Original Investigation | Research
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11. Full Text A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest
by Perkins, Gavin D and Ji, Chen and Deakin, Charles D and Quinn, Tom and Nolan, Jerry P and Scomparin, Charlotte and Regan, Scott and Long, John and Slowther, Anne and Pocock, Helen and Black, John J.M and Moore, Fionna and Fothergill, Rachael T and Rees, Nigel and O’Shea, Lyndsey and Docherty, Mark and Gunson, Imogen and Han, Kyee and Charlton, Karl and Finn, Judith and Petrou, Stavros and Stallard, Nigel and Gates, Simon and Lall, Ranjit and PARAMEDIC2 Collaborators
The New England Journal of Medicine, ISSN 0028-4793, 08/2018, Volume 379, Issue 8, pp. 711 - 721
In a randomized trial involving 8014 patients with out-of-hospital cardiac arrest, the use of epinephrine resulted in a significantly higher rate of 30-day... 
SURVIVAL | MEDICINE, GENERAL & INTERNAL | 2015 INTERNATIONAL CONSENSUS | LIFE-SUPPORT | ADMISSION | CARDIOVASCULAR CARE SCIENCE | RESUSCITATION COUNCIL GUIDELINES | DEFIBRILLATION | OUTCOMES | CARDIOPULMONARY-RESUSCITATION | ADRENALINE | Sympathomimetics - therapeutic use | Cardiopulmonary Resuscitation - methods | Double-Blind Method | Hospital Mortality | Time-to-Treatment | Out-of-Hospital Cardiac Arrest - complications | Humans | Middle Aged | Electric Countershock | Male | Out-of-Hospital Cardiac Arrest - mortality | Survival Rate | United Kingdom | Combined Modality Therapy | Out-of-Hospital Cardiac Arrest - drug therapy | Out-of-Hospital Cardiac Arrest - therapy | Epinephrine - therapeutic use | Nervous System Diseases - etiology | Female | Aged | Emergency Medical Services | Epinephrine | Treatment outcome | Usage | Safety and security measures | Cardiac patients | Analysis | Cardiac arrest | Forecasts and trends | Health aspects | Medical research | Intensive care | Councils | Consent | Medical prognosis | Clinical trials | Patients | Cardiopulmonary resuscitation--CPR | Survival | Drug dosages | Paramedics
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12. Full Text Coronary Artery Disease in Patients With Out-of-Hospital Refractory Ventricular Fibrillation Cardiac Arrest
by Yannopoulos, Demetris and Bartos, Jason A and Raveendran, Ganesh and Conterato, Marc and Frascone, Ralph J and Trembley, Alexander and John, Ranjit and Connett, John and Benditt, David G and Lurie, Keith G and Wilson, Robert F and Aufderheide, Tom P
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2017, Volume 70, Issue 9, pp. 1109 - 1117
The prevalence of coronary artery disease (CAD) among patients with refractory out-of-hospital (OH) ventricular fibrillation (VF)/ventricular tachycardia (VT)... 
emergent cardiac care | cardiopulmonary resuscitation | sudden cardiac death | SURVIVAL | INDUCED HYPOTHERMIA | CARDIAC & CARDIOVASCULAR SYSTEMS | TICAGRELOR | IMPEDANCE THRESHOLD DEVICE | CARDIOPULMONARY-RESUSCITATION | LIFE-SUPPORT | CLOPIDOGREL | OUTCOMES | INTERVENTION | INSIGHTS | United States - epidemiology | Cardiopulmonary Resuscitation - methods | Coronary Artery Disease - surgery | Coronary Artery Disease - etiology | Survival Rate - trends | Out-of-Hospital Cardiac Arrest - complications | Humans | Middle Aged | Ventricular Fibrillation - mortality | Male | Out-of-Hospital Cardiac Arrest - mortality | Hospital Mortality - trends | Young Adult | Out-of-Hospital Cardiac Arrest - therapy | Percutaneous Coronary Intervention - methods | Ventricular Fibrillation - complications | Adolescent | Adult | Female | Aged | Coronary Artery Disease - epidemiology | Retrospective Studies | Transluminal angioplasty | Heart | Care and treatment | Emergency medicine | Abnormalities | Cardiac arrest | Diagnostic imaging | Coronary heart disease | Muscle contraction | Tachycardia | Analysis | Cardiac patients | Cardiology | Emergency medical services | Intervention | Cardiac arrhythmia | Surgical implants | Angiography | Terminal illnesses | Critical care | Cardiovascular disease | Cardiopulmonary resuscitation--CPR | Ventricular fibrillation | Habitability | Reperfusion | Fibrillation | Implants | Lesions | Stents | Heart diseases | Resuscitation | Nursing homes | Automation | Medical imaging | Catheterization | Coronary artery | Coronary artery disease | Patients | Survival | Coronary vessels | Intubation | Ventricle | Acute coronary syndromes | Circulation
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