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1. Full Text Two-step transplantation with adipose tissue-derived stem cells increases follicle survival by enhancing vascularization in xenografted frozen-thawed human ovarian tissue
by Manavella, D D and Cacciottola, L and Pommé, S and Desmet, C M and Jordan, B F and Donnez, J and Amorim, C A and Dolmans, M M
Human Reproduction, ISSN 0268-1161, 06/2018, Volume 33, Issue 6, pp. 1107 - 1116
Abstract STUDY QUESTION Do adipose tissue-derived stem cells (ASCs) enhance vascularization and follicle survival in xenografted ovarian tissue using a... 
vascularization | ovarian tissue transplantation | EPR oximetry | adipose tissue-derived stem cells | xenografting | NUDE-MICE | FERTILITY PRESERVATION | ANGIOGENESIS | GRAFTS | adipose tissue | PRIMORDIAL FOLLICLES | derived stem cells | CHILDHOOD | OBSTETRICS & GYNECOLOGY | MESENCHYMAL STROMAL CELLS | CORTEX TRANSPLANTATION | REPRODUCTIVE BIOLOGY | ELECTRON-PARAMAGNETIC-RESONANCE | NEOVASCULARIZATION | Prospective Studies | Ovary - blood supply | Humans | Adipose Tissue - cytology | Mice, SCID | Ovary - cytology | Mesenchymal Stem Cell Transplantation - methods | Neovascularization, Physiologic - physiology | Animals | Ovarian Follicle - physiology | Female | Mice | Ovarian Follicle - transplantation | Ovary - transplantation | Ovarian Follicle - cytology | Disease Models, Animal
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2. Full Text Correlation of circular RNA abundance with proliferation - Exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues
by Bachmayr-Heyda, Anna and Reiner, Agnes T and Auer, Katharina and Sukhbaatar, Nyamdelger and Aust, Stefanie and Bachleitner-Hofmann, Thomas and Mesteri, Ildiko and Grunt, Thomas W and Zeillinger, Robert and Pils, Dietmar
Scientific Reports, ISSN 2045-2322, 2015, Volume 5, Issue 1, p. 8057
Circular RNAs are a recently (re-) discovered abundant RNA species with presumed function as miRNA sponges, thus part of the competing endogenous RNA network.... 
ALIGNMENT | INHIBITOR | MULTIDISCIPLINARY SCIENCES | PULMONARY-FIBROSIS | Caco-2 Cells | Cell Line | Intestinal Mucosa - metabolism | Cell Proliferation | Epithelial Cells - metabolism | Colorectal Neoplasms - genetics | Humans | Middle Aged | Ovarian Neoplasms - pathology | Male | HT29 Cells | Ovarian Neoplasms - genetics | Lung Diseases - genetics | Sequence Analysis, RNA | Aged, 80 and over | Adult | Female | Aged | Lung Diseases - pathology | Colorectal Neoplasms - pathology | Epithelial Cells - cytology | Real-Time Polymerase Chain Reaction | Exoribonucleases - metabolism | RNA - metabolism | Epithelial cells | Lung cancer | Lung diseases | Colorectal carcinoma | Mucosa | MiRNA | Colorectal cancer | Tumor cell lines | Ribonucleic acid--RNA | Ovarian cancer | Isoforms | Fibrosis | Circular RNA | Colon | Tumors
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3. Full Text Extracellular matrix remodeling: The common denominator in connective tissue diseases possibilities for evaluation and current understanding of the matrix as more than a passive architecture, but a key player in tissue failure
by Karsdal, Morten A and Nielsen, Mette J and Sand, Jannie M and Henriksen, Kim and Genovese, Federica and Bay-Jensen, Anne-Christine and Smith, Victoria and Adamkewicz, Joanne I and Christiansen, Claus and Leeming, Diana J
Assay and Drug Development Technologies, ISSN 1540-658X, 03/2013, Volume 11, Issue 2, pp. 70 - 92
Increased attention is paid to the structural components of tissues. These components are mostly collagens and various proteoglycans. Emerging evidence... 
GLYCATION END-PRODUCT | HUMAN ARTICULAR-CARTILAGE | MULTIPLE EPIPHYSEAL DYSPLASIA | KERATAN SULFATE PROTEOGLYCAN | SYSTEMIC-LUPUS-ERYTHEMATOSUS | HEPATIC STELLATE CELLS | POSTTRANSLATIONAL PROTEIN MODIFICATIONS | BIOCHEMICAL RESEARCH METHODS | PHARMACOLOGY & PHARMACY | IDIOPATHIC PULMONARY-FIBROSIS | EPITHELIAL OVARIAN-CANCER | SINGLE-BASE MUTATION | Animals | Models, Biological | Connective Tissue Diseases - pathology | Humans | Extracellular Matrix - metabolism | Elastic Modulus | Protein Processing, Post-Translational | Connective Tissue Diseases - metabolism | Extracellular Matrix - pathology | Extracellular Matrix Proteins - metabolism
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4. Full Text Transplantation of ovarian tissue
by Donnez, Jacques, MD, PhD and Dolmans, Marie-Madeleine, MD, PhD
Best Practice & Research: Clinical Obstetrics & Gynaecology, ISSN 1521-6934, 2014, Volume 28, Issue 8, pp. 1188 - 1197
Since the first live birth after orthotopic transplantation of frozen–thawed ovarian tissue, >40 babies have been born. It is time to consider fertility... 
Obstetrics and Gynecology | complications | pregnancy outcome | ovarian transplantation | FERTILITY PRESERVATION | BONE-MARROW-TRANSPLANTATION | LIVE BIRTH | AUTOLOGOUS TRANSPLANTATION | CRYOPRESERVATION | RESTORATION | CANCER | MONOZYGOTIC TWINS | PREGNANCY | OBSTETRICS & GYNECOLOGY | YOUNG PATIENT | Pregnancy | Humans | Female | Fertility Preservation - methods | Ovarian Follicle - transplantation | Ovary - transplantation | Pregnancy Outcome | Pregnancy Rate | Infertility, Female - therapy
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5. Full Text Ninety-five orthotopic transplantations in 74 women of ovarian tissue after cytotoxic treatment in a fertility preservation network: tissue activity, pregnancy and delivery rates
by Van der Ven, H and Liebenthron, J and Beckmann, M and Toth, B and Korell, M and Krüssel, J and Frambach, T and Kupka, M and Hohl, M.K and Winkler-Crepaz, K and Seitz, S and Dogan, A and Griesinger, G and Häberlin, F and Henes, M and Schwab, R and Sütterlin, M and von Wolff, M and Dittrich, R and FertiPROTEKT Network and FertiPROTEKT network
Human Reproduction, ISSN 0268-1161, 09/2016, Volume 31, Issue 9, pp. 2031 - 2041
Abstract STUDY QUESTION What is the success rate in terms of ovarian activity (menstrual cycles) as well as pregnancy and delivery rates 1 year after... 
Ovary | Chemotherapy | Fertility preservation | Ovarian tissue | Delivery rate | Pregnancy rate | Transplantation | Radiotherapy | Peritoneum | peritoneum | TRANSPORTATION | pregnancy rate | 1ST LIVE BIRTH | CRYOPRESERVATION | RESTORATION | chemotherapy | CANCER | OBSTETRICS & GYNECOLOGY | ovary | REPRODUCTIVE BIOLOGY | delivery rate | transplantation | radiotherapy | LYMPHOMA | fertility preservation | ovarian tissue | AGE | Pregnancy | Follow-Up Studies | Primary Ovarian Insufficiency - surgery | Humans | Adult | Female | Fertility Preservation - methods | Ovary - transplantation | Retrospective Studies | Cryopreservation - methods | Pregnancy Outcome | Pregnancy Rate
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6. Full Text A Mutation in fat2 Uncouples Tissue Elongation from Global Tissue Rotation
by Aurich, Franziska and Dahmann, Christian
Cell Reports, ISSN 2211-1247, 03/2016, Volume 14, Issue 11, pp. 2503 - 2510
Global tissue rotation was proposed as a morphogenetic mechanism controlling tissue elongation. In ovaries, global tissue rotation of egg chambers coincides... 
EGG CHAMBER ELONGATION | MATRIX | MORPHOGENESIS | MISSHAPEN | REVOLUTIONS | LAMININ | OVARIAN FOLLICLES | ACTIN BUNDLES | DROSOPHILA FOLLICULAR EPITHELIUM | PLANAR POLARITY | CELL BIOLOGY | Collagen Type IV - metabolism | Immunohistochemistry | Cell Polarity | Cadherins - metabolism | Actins - metabolism | Drosophila Proteins - metabolism | Time-Lapse Imaging | Ovum - cytology | Animals | Mutagenesis | Female | Drosophila - metabolism | Drosophila Proteins - genetics | Mutation | Cadherins - genetics | Drosophila - genetics | Ovary - metabolism | Ovum - metabolism
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7. Full Text Optimal vitrification protocol for mouse ovarian tissue cryopreservation: effect of cryoprotective agents and in vitro culture on vitrified–warmed ovarian tissue survival
by Youm, Hye Won and Lee, Jung Ryeol and Lee, Jaewang and Jee, Byung Chul and Suh, Chang Suk and Kim, Seok Hyun
Human Reproduction, ISSN 0268-1161, 4/2014, Volume 29, Issue 4, pp. 720 - 730
STUDY QUESTION What is the optimal vitrification protocol according to the cryoprotective agent (CPA) for ovarian tissue (OT) cryopreservation? SUMMARY ANSWER... 
Transplantation | Fertility preservation | In vitro culture | Ovarian tissue | Vitrification | Follicle Stimulating Hormone - metabolism | Cell Proliferation | Ovary - physiology | Mice, Inbred Strains | Ovary - cytology | Cryopreservation - methods | Cryoprotective Agents - pharmacology | Animals | Female | Ovary - drug effects | Mice | Apoptosis | Index Medicus
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8. Full Text Ovarian tissue freezing: Current status
by Donnez, Jacques and Dolmans, Marie-Madeleine
Current Opinion in Obstetrics and Gynecology, ISSN 1040-872X, 06/2015, Volume 27, Issue 3, pp. 222 - 230
Purpose of review This article aims to carefully evaluate a number of critical points related to ovarian tissue freezing and presents factual data in terms of... 
reimplantation | ovary | ovarian tissue cryopreservation | freezing | FERTILITY PRESERVATION | BONE-MARROW-TRANSPLANTATION | BILATERAL OOPHORECTOMY | OBSTETRICS & GYNECOLOGY | BREAST-CANCER | IN-VITRO | CANCER-PATIENTS | VITRO MATURED OOCYTES | ANTRAL FOLLICLES | MALIGNANT-CELLS | BENIGN DISEASE | Reproductive Techniques | Neoplasms - complications | Neoplasms - therapy | Antineoplastic Agents - adverse effects | Humans | Fertilization in Vitro - methods | Female | Fertility Preservation - methods | Neoplasms - physiopathology | Tissue Transplantation - methods | Cryopreservation - methods
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9. Full Text Translational research aiming to improve survival of ovarian tissue transplants using adipose tissue‐derived stem cells
by Dolmans, Marie‐Madeleine and Cacciottola, Luciana and Amorim, Christiani A and Manavella, Diego
Acta Obstetricia et Gynecologica Scandinavica, ISSN 0001-6349, 05/2019, Volume 98, Issue 5, pp. 665 - 671
There is now sufficient evidence to support the feasibility and efficacy of ovarian tissue (OT) cryopreservation and transplantation for both fertility... 
hypoxia | apoptosis | adipose tissue‐derived stem cells | ovarian tissue transplantation | follicle survival | CRITERIA | FERTILITY PRESERVATION | ANGIOGENESIS | adipose tissue-derived stem cells | OBSTETRICS & GYNECOLOGY | PO2 | OXIMETRY | THERAPY | ELECTRON-PARAMAGNETIC-RESONANCE | CORTEX | FOLLICLES | STROMAL CELLS | Adipose tissues | Stem cell research | Fibrin | Transplantation | Analysis | Stem cells
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10. Full Text Live birth after autograft of ovarian tissue cryopreserved during childhood
by Demeestere, Isabelle and Simon, Philippe and Dedeken, Laurence and Moffa, Federica and Tsépélidis, Sophie and Brachet, Cecile and Delbaere, Anne and Devreker, Fabienne and Ferster, Alina
Human Reproduction, ISSN 0268-1161, 09/2015, Volume 30, Issue 9, pp. 2107 - 2109
Ovarian insufficiency is a major long-term adverse event, following the administration of a myeloablative conditioning regimen, and occurring in >80% of... 
fertility preservation | ovarian tissue cryopreservation | childhood | live birth | transplantation | ADOLESCENCE | INDUCTION | PUBERTY | DECLINE | OBSTETRICS & GYNECOLOGY | REPRODUCTIVE BIOLOGY | FOLLICLES | OOCYTES | AGE | Myeloablative Agonists - adverse effects | Humans | Live Birth | Transplantation, Autologous | Autografts - transplantation | Fertility Preservation - methods | Primary Ovarian Insufficiency - chemically induced | Pregnancy | Anemia, Sickle Cell - therapy | Cryopreservation | Adolescent | Adult | Female | Ovary - transplantation
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11. Full Text Xenotransplantation of cryopreserved human ovarian tissue—a systematic review of MII oocyte maturation and discussion of it as a realistic option for restoring fertility after cancer treatment
by Dittrich, Ralf, Ph.D and Lotz, Laura, M.D and Fehm, Tanja, M.D and Krüssel, Jan, M.D and von Wolff, Michael, M.D and Toth, Bettina, M.D and van der Ven, Hans, Ph.D and Schüring, Andreas N., M.D and Würfel, Wolfgang, M.D and Hoffmann, Inge and Beckmann, Matthias W., M.D
Fertility and Sterility, ISSN 0015-0282, 2015, Volume 103, Issue 6, pp. 1557 - 1565
Objective To systematically review the reporting of MII (MII) oocyte development after xenotransplantation of human ovarian tissue. Design Systematic review in... 
Internal Medicine | Obstetrics and Gynecology | Fertility preservation | ovarian tissue xenotransplantation | ovarian tissue cryopreservation | IMMUNODEFICIENT MICE | SCID MICE | FIBRIN SCAFFOLD | ARTIFICIAL OVARY | CELL CONTAMINATION | PRIMORDIAL FOLLICLES | PRESERVE FERTILITY | OBSTETRICS & GYNECOLOGY | REPRODUCTIVE BIOLOGY | FOLLICULAR DEVELOPMENT | ANTRAL FOLLICLES | PARKINSONS-DISEASE | Oocytes - growth & development | Cell Survival | Humans | Cells, Cultured | Transplantation, Heterologous | Fertility Preservation - methods | Mice, SCID | Oocytes - transplantation | Neoplasms - complications | Oocytes - cytology | Oogenesis | Neoplasms - therapy | Animals | Cryopreservation | Female | Mice | Neoplasms - pathology | Oocyte Retrieval - methods | Transplantation of organs, tissues, etc | Care and treatment | Cancer
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12. Full Text Expression Quantitative Trait loci (QTL) in tumor adjacent normal breast tissue and breast tumor tissue
by Quiroz-Zaârate, Alejandro and Harshfield, Benjamin J and Hu, Rong and Knoblauch, Nick and Beck, Andrew H and Hankinson, Susan E and Carey, Vincent and Tamimi, Rulla M and Hunter, David J and Quackenbush, John and Hazra, Aditi
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, p. e0170181
We investigate 71 single nucleotide polymorphisms (SNPs) identified in meta-analytic studies of genome-wide association studies (GWAS) of breast cancer, the... 
CANCER RISK | ALLELES | VARIANTS | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | GENES | OVARIAN | ASSOCIATION | Genome-Wide Association Study | United States | Humans | Gene Expression Profiling | Breast - metabolism | Formaldehyde | Paraffin Embedding | Breast Neoplasms - genetics | Health Surveys | Nurses | Aged, 80 and over | Female | Aged | Polymorphism, Single Nucleotide | Tissue Fixation | Quantitative Trait Loci | Quantitative genetics | Development and progression | Breast cancer | Genetic aspects | Single nucleotide polymorphisms | Analysis | Health care | Genes | Genomes | Single-nucleotide polymorphism | Tissue analysis | Paraffin | Epidemiology | Medical schools | Pathways | Genetics | Bioinformatics | Public health | Medical personnel | Invasiveness | Chromosome 6 | Preventive medicine | Gene expression | Loci | Post-menopause | Quantitative trait loci | Studies | Hospitals | Womens health | Breast | Cancer | Tumors
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13. Full Text Tissue transglutaminase links TGF-Β, epithelial to mesenchymal transition and a stem cell phenotype in ovarian cancer
by Cao, L and Shao, M and Schilder, J and Guise, T and Mohammad, K.S and Matei, D
Oncogene, ISSN 0950-9232, 05/2012, Volume 31, Issue 20, pp. 2521 - 2534
Tissue transglutaminase (TG2), an enzyme involved in cell proliferation, differentiation and apoptosis is over-expressed in ovarian carcinomas, where it... 
epithelial to mesenchymal transition | TGF-β | cancer stem cells | metastasis | ovarian cancer | TG2 | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | E-CADHERIN | KAPPA-B | SANDWICH DOMAIN | CELL BIOLOGY | TGF-beta | GROWTH-FACTOR-BETA | ONCOLOGY | PATHWAY | METASTATIC BREAST-CANCER | GENETICS & HEREDITY | GENE-EXPRESSION | UP-REGULATION | CARCINOMA | Humans | Hyaluronan Receptors | Ovarian Neoplasms - pathology | Transglutaminases - genetics | Epithelial-Mesenchymal Transition - genetics | Proto-Oncogene Proteins c-kit | Ovarian Neoplasms - enzymology | Neoplasm Metastasis | Transforming Growth Factor beta - genetics | Neoplastic Stem Cells - metabolism | Transglutaminases - metabolism | Cell Line, Tumor | Neoplastic Stem Cells - pathology | Female | Enzyme Activation | GTP-Binding Proteins | Transforming Growth Factor beta - metabolism | Cell proliferation | Smad protein | Cytokines | Mesenchyme | Ovarian carcinoma | Transcription | Transforming growth factor | Transforming growth factor- beta | Transglutaminase 2 |