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The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 03/2017, Volume 102, Issue 3, pp. 810 - 821
We found serum lipid profiles changed in women with PCOS. Obesity and compensatory hyperinsulinemia promoted the metabolism of arachidonic acid and other PUFAs, whereas androgen had an inhibitory effect. Abstract Context... 
POLYCYSTIC-OVARY-SYNDROME | IONIZATION-MASS-SPECTROMETRY | RISK-FACTORS | TESTOSTERONE | BIOLOGICAL SAMPLES | ENDOCRINOLOGY & METABOLISM | IMPAIRED GLUCOSE-TOLERANCE | NONALCOHOLIC STEATOHEPATITIS | FAT-CELL LIPOLYSIS | OLDER CHINESE | OBESE WOMEN | Arachidonic Acid - metabolism | Gas Chromatography-Mass Spectrometry | Linoleic Acid - metabolism | Humans | Dehydroepiandrosterone Sulfate - metabolism | Case-Control Studies | Young Adult | Testosterone - metabolism | Polycystic Ovary Syndrome - complications | Diet, High-Fat | Mass Spectrometry | Chromatography, Liquid | Adult | Female | Hyperandrogenism - metabolism | Fatty Acids - metabolism | Phosphatidylglycerols - metabolism | Disease Models, Animal | Hyperinsulinism - metabolism | Ceramides - metabolism | Hyperinsulinism - complications | Polycystic Ovary Syndrome - metabolism | Cholesterol, HDL - metabolism | Obesity - complications | Eicosapentaenoic Acid - metabolism | Rats | Sex Hormone-Binding Globulin - metabolism | Lipid Metabolism | Fatty Acids, Unsaturated - metabolism | Rats, Sprague-Dawley | Obesity - metabolism | Triglycerides - metabolism | Hyperandrogenism - complications | Insulin - metabolism | Animals | Cholesterol, LDL - metabolism | Phosphatidic Acids - metabolism | Androgens - metabolism | Blood Glucose - metabolism | Docosahexaenoic Acids - metabolism | Polycystic ovary syndrome | Obesity | Hyperinsulinemia | Lecithin | Polyunsaturated fatty acids | Lipids | Mass spectroscopy | Liquid chromatography | Phospholipids | Metabolism | Arachidonic acid | Insulin | Fatty acids | Patients | Chromatography | Biological activity | Subgroups | Gas chromatography | Androgens | Molecular modelling | Metabolites | Lipid metabolism | Mass spectrometry | Metabolic disorders
Journal Article
Best Practice & Research: Clinical Obstetrics & Gynaecology, ISSN 1521-6934, 2016, Volume 37, pp. 66 - 79
Women with polycystic ovarian syndrome (PCOS) present with several endometrial abnormalities possibly explaining some of the adverse endometrium-related... 
Obstetrics and Gynecology | endometrium | endometrial cancer | PCOS | pregnancy complications | inflammation | hyperinsulinemia | MENSTRUAL-CYCLE | ESTROGEN-RECEPTORS | TROPHOBLAST INVASION | OBSTETRICS & GYNECOLOGY | BREAST-CANCER | PLASMA TESTOSTERONE | ANDROGEN RECEPTOR EXPRESSION | IN-VITRO | INSULIN-RECEPTOR | SPONTANEOUS-ABORTION | FACTOR-BINDING PROTEIN-1 | Glucose Transport Proteins, Facilitative - metabolism | Polycystic Ovary Syndrome - epidemiology | Pre-Eclampsia - epidemiology | Receptors, Estrogen - metabolism | Killer Cells, Natural | Homeodomain Proteins - metabolism | Humans | Receptors, Androgen - metabolism | Endometrial Neoplasms - metabolism | Hypertension, Pregnancy-Induced - metabolism | Integrin alphaVbeta3 - metabolism | Antigens, CD - metabolism | Receptors, Progesterone - metabolism | Abortion, Spontaneous - epidemiology | Abortion, Spontaneous - metabolism | Female | Chemokine CCL2 - metabolism | Pre-Eclampsia - metabolism | Pregnancy Complications - metabolism | Interleukin-6 - metabolism | Endometrium - metabolism | Nuclear Receptor Coactivators - metabolism | Polycystic Ovary Syndrome - metabolism | Premature Birth - metabolism | Endometrial Neoplasms - epidemiology | Premature Birth - epidemiology | Embryo Implantation | Obesity - metabolism | Pregnancy | Insulin-Like Growth Factor Binding Protein 1 - metabolism | Obesity - epidemiology | Hypertension, Pregnancy-Induced - epidemiology | Receptor, Insulin - metabolism | Pregnancy Complications - epidemiology | Glucose metabolism | Endometrial cancer | Stein-Leventhal syndrome | Physiological aspects | Progesterone | Integrins | Protein binding
Journal Article
European Journal of Endocrinology, ISSN 0804-4643, 10/2014, Volume 171, Issue 4, pp. P1 - P29
Polycystic ovary syndrome (PCOS) is the most common ovarian disorder associated with androgen excess in women, which justifies the growing interest of... 
OBSTRUCTIVE SLEEP-APNEA | ENDOCRINOLOGY & METABOLISM | SYMPATHETIC-NERVE ACTIVITY | FOLLICLE-STIMULATING-HORMONE | IMPAIRED GLUCOSE-TOLERANCE | QUALITY-OF-LIFE | TANDEM MASS-SPECTROMETRY | ANTI-MULLERIAN-HORMONE | ANDROGEN RECEPTOR GENE | LOW-DOSE FLUTAMIDE | TYPE-2 DIABETES-MELLITUS | Body Composition | Glucose Intolerance - metabolism | Polycystic Ovary Syndrome - etiology | Cardiovascular Diseases - prevention & control | Humans | Polycystic Ovary Syndrome - diagnosis | Testosterone - metabolism | Polycystic Ovary Syndrome - complications | Glucose Intolerance - etiology | Ultrasonography | Infertility, Female - etiology | Female | Obesity - etiology | Polycystic Ovary Syndrome - psychology | Concept Formation | Ovary - metabolism | Bariatric Surgery | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - etiology | Gonadal Steroid Hormones - metabolism | Ovary - pathology | Polycystic Ovary Syndrome - metabolism | Cardiovascular Diseases - metabolism | Risk Reduction Behavior | Obesity - complications | Insulin Resistance | Biomarkers - blood | Infertility, Female - metabolism | Obesity - metabolism | Polycystic Ovary Syndrome - therapy | Phenotype | Obesity - therapy | Ovary - diagnostic imaging | Glucose - metabolism | Quality of Life | Androgens - metabolism | Lipid Peroxidation | Infertility, Female - therapy
Journal Article
Developmental cell, ISSN 1534-5807, 2015, Volume 33, Issue 1, pp. 36 - 46
Organ wasting, related to changes in nutrition and metabolic activity of cells and tissues, is observed under conditions of starvation and in the context... 
HYPERTROPHY | PROTEIN | GENE | RNA | MECHANISM | PATHWAY | GROWTH | STEM-CELL PROLIFERATION | INFECTION | DEVELOPMENTAL BIOLOGY | DROSOPHILA | CELL BIOLOGY | Metabolomics | Wasting Syndrome - metabolism | Oligonucleotide Array Sequence Analysis | Male | Muscle, Skeletal - metabolism | Gene Expression Profiling | Stem Cells - cytology | Drosophila Proteins - metabolism | Muscle, Skeletal - cytology | Ovary - cytology | Stem Cells - metabolism | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Fat Body - cytology | Hyperglycemia - pathology | Trans-Activators - genetics | Female | Nuclear Proteins - genetics | Fat Body - metabolism | Insulin Secretion | Real-Time Polymerase Chain Reaction | Ovary - metabolism | Biomarkers - metabolism | RNA, Messenger - genetics | Cells, Cultured | Hemolymph - metabolism | Nuclear Proteins - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Animals, Genetically Modified - metabolism | Blotting, Western | Gastrointestinal Tract - metabolism | Hyperglycemia - metabolism | Insulin - metabolism | Animals | Animals, Genetically Modified - growth & development | Animals, Genetically Modified - genetics | Insulin - chemistry | Drosophila melanogaster - growth & development | Trans-Activators - metabolism | Gastrointestinal Tract - cytology | Drosophila Proteins - genetics | Insulin-Like Growth Factor I - antagonists & inhibitors | Insulin-Like Growth Factor I - metabolism | Wasting Syndrome - pathology | Enzymes | Starvation | Analysis | Stem cells | Physiological aspects | Development and progression | Cellular signal transduction | Ovarian cancer | Medical colleges | Resveratrol
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 10, p. e48643
... and Neuroscience, Albert Einstein College of Medicine, New York, New York, United States of America Jens C. Bruning Affiliation: Department of Mouse Genetics and Metabolism... 
DIABETES-MELLITUS | POMC NEURONS | VISCERAL FAT | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | IMPAIRED GLUCOSE-TOLERANCE | NECROSIS-FACTOR-ALPHA | KAPPA-B | FAT DISTRIBUTION | THECA-INTERSTITIAL CELLS | ADIPOSE-TISSUE | Liver - pathology | Polycystic Ovary Syndrome - blood | Receptors, Leptin - genetics | Humans | Male | Tomography, X-Ray Computed | Interleukin-1beta - genetics | Interleukin-1beta - blood | Adipose Tissue - metabolism | Inflammation - metabolism | Interleukin-1beta - metabolism | Interleukin-6 - blood | Receptor, Insulin - genetics | Female | Interleukin-6 - metabolism | Disease Models, Animal | Ovary - metabolism | Gene Expression | Ovary - pathology | Ovulation - genetics | Polycystic Ovary Syndrome - metabolism | Interleukin-6 - genetics | Liver - metabolism | Adipose Tissue - pathology | Reverse Transcriptase Polymerase Chain Reaction | Adipocytes - pathology | Mice, Knockout | Pregnancy | Magnetic Resonance Imaging | Animals | Adipocytes - metabolism | Polycystic Ovary Syndrome - genetics | Inflammation - genetics | Receptor, Insulin - metabolism | Mice | Receptors, Leptin - metabolism | Blood Glucose - metabolism | Hypertrophy | Adipose tissues | Type 2 diabetes | Cytokines | RNA | Liver | Inflammation | B cells | Research | Insulin | Stein-Leventhal syndrome | Analysis | Leptin | Physiological aspects | Insulin resistance | Intermedin | Diabetes therapy | Adipose tissue | Body fat | Pathogenesis | Systematic review | Proopiomelanocortin | Estrus cycle | Glucose | Macrophages | Body composition | Receptors | Hyperglycemia | Computed tomography | Body composition (biology) | Insulin receptors | Etiology | Obesity | Polycystic ovary syndrome | Estrus | Therapeutic applications | Diabetes mellitus | Health risks | Gene expression | Ovulation | Infiltration
Journal Article
American journal of physiology: endocrinology and metabolism, ISSN 1522-1555, 2019, Volume 316, Issue 1, pp. E16 - E33
...)B-lipoprotein and insulin-glucose metabolism, and endocrine-reproductive indices in a PCOS-prone MetS rodent... 
lipid and insulin metabolism | flutamide | metformin | PCOS | POLYCYSTIC-OVARY-SYNDROME | INTIMA-MEDIA THICKNESS | PHYSIOLOGY | OBESE WOMEN | GLUCOSE-HOMEOSTASIS | ENDOCRINOLOGY & METABOLISM | CARDIOVASCULAR-DISEASE | RECEPTOR GENE | PARTICLE-SIZE | YOUNG-WOMEN | CAG REPEAT POLYMORPHISM | HYPOCALORIC DIET | Apolipoproteins B - metabolism | Cardiovascular Diseases | Intestinal Mucosa - metabolism | Apolipoprotein B-48 - metabolism | Metabolic Syndrome - metabolism | Risk | Mitogen-Activated Protein Kinase 1 - drug effects | Apolipoproteins B - drug effects | Apolipoprotein B-100 - metabolism | Ovarian Follicle - drug effects | Liver - drug effects | Female | Ovary - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Disease Models, Animal | Follicular Phase | Polycystic Ovary Syndrome - metabolism | Liver - metabolism | Metformin - pharmacology | Insulin Resistance | Androgen Antagonists - pharmacology | Rats | Flutamide - pharmacology | Hypoglycemic Agents - pharmacology | Triglycerides - metabolism | Blood Glucose - drug effects | Estrogen Receptor alpha - drug effects | Insulin - metabolism | Animals | Estrogen Receptor alpha - genetics | Receptor, Insulin - drug effects | Receptor, Insulin - metabolism | Apolipoprotein B-100 - drug effects | Apolipoprotein B-48 - drug effects | Blood Glucose - metabolism | RNA, Messenger | Mitogen-Activated Protein Kinase 1 - metabolism | Proto-Oncogene Proteins c-akt - drug effects | Drugs | Estrogens | Estrogen | Dyslipidemia | Estrogen receptors | Lipids | Effects | Glucose | Risk factors | Glucose metabolism | Signal transduction | Pathways | Intestine | Rodents | Lipid metabolism | Diabetes mellitus (non-insulin dependent) | Polycystic ovary syndrome | Secretion | Diabetes mellitus | AKT2 protein | Health risks | Triglycerides | Risk analysis | Gene expression | Apolipoproteins | Metabolism | Insulin | Glucose tolerance | Intolerance | Signaling | Androgens | Flutamide | Hypertriglyceridemia | Metformin | Cardiovascular diseases | Metabolic disorders
Journal Article
Fish Physiology and Biochemistry, ISSN 0920-1742, 9/2011, Volume 37, Issue 3, pp. 619 - 647
The molecular mechanisms controlling sex determination and differentiation in zebrafish (Danio rerio) are largely unknown. A genome-wide analysis may provide... 
Life Sciences | Testis | Animal Physiology | Ovary | Animal Biochemistry | Sex differentiation | Zoology | Proteomics | Freshwater & Marine Ecology | Zebrafish | Animal Anatomy / Morphology / Histology | Multidimensional protein identification technology (MudPIT) | PHYSIOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | WD40 REPEAT PROTEIN | ENDOPLASMIC-RETICULUM STRESS | PRIMORDIAL GERM-CELLS | LASER-CAPTURE MICRODISSECTION | MIGRATION-INHIBITORY FACTOR | TO-AUTOINTEGRATION FACTOR | FISHERIES | MESSENGER-RNA | SEX DETERMINATION | GENE-EXPRESSION | GROWTH-FACTOR-I | Egg Proteins - metabolism | Phosphorylation | Testis - metabolism | Cyclin-Dependent Kinases - metabolism | Membrane Glycoproteins - metabolism | Male | RNA - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Cell Cycle Proteins - genetics | Female | Septins - metabolism | Cyclin-Dependent Kinases - genetics | Cytokines - genetics | Ovary - metabolism | RNA - metabolism | Dyneins - metabolism | Zona Pellucida Glycoproteins | Septins - genetics | Vitellogenins - metabolism | Cytokines - metabolism | Cell Cycle Proteins - metabolism | Intercellular Signaling Peptides and Proteins - genetics | Gene Expression Regulation - physiology | Receptors, Cell Surface - metabolism | Vitellogenins - genetics | DNA - metabolism | Sex Characteristics | Membrane Glycoproteins - genetics | DNA - genetics | Animals | Zebrafish - metabolism | SOX Transcription Factors - metabolism | SOX Transcription Factors - genetics | Signal Transduction - physiology | Dyneins - genetics | Egg Proteins - genetics | Apoptosis | Receptors, Cell Surface - genetics | Proteins | Anopheles | Messenger RNA | Analysis | Genomics | Index Medicus
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 03/2017, Volume 102, Issue 3, pp. 840 - 848
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 3, p. e59825
... substrate availability and metabolism in a mouse model of familial Alzheimer's (3xTgAD). Results of these analyses indicated that ovarian hormones deprivation by ovariectomy (OVX... 
POSITRON-EMISSION-TOMOGRAPHY | HORMONE-THERAPY | MULTIDISCIPLINARY SCIENCES | BRAIN GLUCOSE-METABOLISM | AEROBIC GLYCOLYSIS | IN-VIVO | A-BETA | HEXOKINASE-ACTIVITY | AMYLOID-BETA-PROTEIN | RAT-BRAIN | ENERGY-METABOLISM | L-Lactate Dehydrogenase - metabolism | Body Weight | Positron-Emission Tomography | X-Ray Microtomography | Isoenzymes - metabolism | Amyloid beta-Peptides - metabolism | Female | Neurons - metabolism | Estrogens - metabolism | Skin Temperature | Disease Models, Animal | Ovary - metabolism | Estradiol - metabolism | Ovariectomy | Gene Expression Regulation | Mice, Transgenic | Mitochondria - metabolism | Hippocampus - metabolism | Animals | Lactates - metabolism | Brain - pathology | Glucose - metabolism | Glycolysis | Mice | Alzheimer Disease - genetics | Brain | Glucose metabolism | Neurons | Physiological aspects | Genetic engineering | Genetic aspects | Glucose | Gene expression | Estradiol | Alzheimer's disease | Dextrose | Cytochrome | Energy metabolism | Estrogens | Ketone bodies | Hormones | Proteins | Mitochondria | Bioenergetics | Aging | Availability | Glucose transporter | Preservation | Neurodegenerative diseases | Metabolism | Glucose transport | Substrates | Neurology | Sex hormones | Pharmacy | Transporter | Neuroimaging | Neurosciences | Senescence | 17β-Estradiol | Kinases | Energy resources | Rodents | Pharmaceutical sciences | Deprivation | Medical imaging | Ketones | Transgenic mice | CoA transferase | Pharmacology | Fuel technology | Hexokinase | Lactic acid | Respiration | Laboratory animals | Alzheimers disease | Alternative fuels
Journal Article