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UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, ISSN 1306-133X, 2018, Volume 28, Issue 4, pp. 261 - 264
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 08/2019, pp. 1 - 2
The five articles in this multi-author review in CMLS provide examples of multi-functionality of proteins belonging to several families. Distinct structural... 
Proteins | Overexpression | Functionals | Therapeutic applications | Protein families
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 09/2018, Volume 66, Issue 36, pp. 9446 - 9455
Ginsenosides attract great attention for their bioactivities. However, their contents are low, and many UDP-glycosyltransferases (UGTs) that play crucial roles... 
site-directed mutagenesis | ginsenoside | overexpression | UGTs | biosynthesis
Journal Article
11/2012
Systematic genomic studies in the budding yeast S. cerevisiae have greatly increased our capacity to conduct functional profiling of the eukaryotic genome. I... 
0369 | genetics | kinases | overexpression | genomics | 0307 | barcode | yeast
Dissertation
International journal of molecular sciences, ISSN 1422-0067, 05/2019, Volume 20, Issue 9, p. 2228
Ubiquitination is one of the main post-translational modification of proteins. It plays key roles in a broad range of cellular functions, including protein... 
GTEx | GEPIA | UALCAN | overexpression | UBE2C | cancer | TCGA
Journal Article
Medicine (United States), ISSN 0025-7974, 12/2017, Volume 96, Issue 52
Journal Article
Acta Horticulturae Sinica, ISSN 0513-353X, 08/2018, Volume 45, Issue 8, pp. 1523 - 1534
Journal Article
Oncogene, ISSN 0950-9232, 05/2011, Volume 30, Issue 18, pp. 2087 - 2097
  P16 Ink4a is a protein involved in regulation of the cell cycle. Currently, p16 Ink4a is considered a tumor suppressor protein because of its physiological... 
senescence | cancer | overexpression | p16 | high grade | Proteins | Gene expression | Cell cycle | Cancer
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 11/2012, Volume 423, Issue 4, pp. 648 - 659
BL21(DE3) is widely used to overexpress proteins. In this overexpression host, the gene encoding the target protein is located on a plasmid and is under... 
membrane protein biogenesis | membrane protein functional/structural studies | T7 RNA polymerase‐based overexpression | membrane protein production | optimization of protein expression | T7 RNA polymerase-based overexpression | SYSTEM | BIOCHEMISTRY & MOLECULAR BIOLOGY | 17 RNA polymerase-based overexpression | HOSTS | COUPLED-RECEPTORS | BACTERIOPHAGE-T7 | ENHANCE | GENES | PURIFICATION | EXPRESSION | RNA-POLYMERASE | Recombinant Fusion Proteins - biosynthesis | Promoter Regions, Genetic | Gene Expression | Bacteriophage T7 - genetics | Membrane Proteins - genetics | Viral Proteins - genetics | DNA-Directed RNA Polymerases - genetics | N-Acetylmuramoyl-L-alanine Amidase - genetics | Viral Proteins - metabolism | Membrane Proteins - biosynthesis | Escherichia coli - genetics | Escherichia coli - metabolism | Recombinant Fusion Proteins - genetics | Membrane Proteins - metabolism | DNA-Directed RNA Polymerases - metabolism | Gene Expression Regulation, Bacterial | RNA | Genes | Escherichia coli | Fluorescence | Biosynthesis | RNA polymerases | Lysozyme | Membrane proteins | Protein binding | Index Medicus | Side effects | Plasmids | Rhamnose | Cytoplasmic membranes | Chromosomes | DNA-directed RNA polymerase | Promoters | Structure-function relationships | Biological Sciences | Naturvetenskap | Biokemi och molekylärbiologi | Biologiska vetenskaper | Biochemistry and Molecular Biology | Natural Sciences
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2018, Volume 36, Issue 6, pp. 536 - 542
PurposeDetection of specific molecular alterations in tumors guides the selection of effective targeted treatment of patients with several types of cancer.... 
CELL LUNG-CANCER | TRIAL | OVEREXPRESSION | AMPLIFICATION | GENE | ONCOLOGY | THYROID-CARCINOMA | HER2 EXPRESSION | BRAF V600E MUTATION | METASTATIC COLORECTAL-CANCER | VEMURAFENIB
Journal Article
Blood, ISSN 0006-4971, 06/2010, Volume 115, Issue 25, pp. 5202 - 5213
Aurora-A is a mitotic kinase that regulates mitotic spindle formation and segregation. In multiple myeloma (MM), high Aurora-A gene expression has been... 
OVEREXPRESSION | ACTIVATION | PROTEIN-KINASE | BONE-MARROW | TARGETS | AGENTS | G2 CHECKPOINT | HEMATOLOGY | CANCER | EVENT
Journal Article
TRANSLATIONAL ONCOLOGY, ISSN 1936-5233, 04/2018, Volume 11, Issue 2, pp. 358 - 365
Class III ss-tubulin (TUBB3) overexpression in ovarian cancer (OC) associates with poor prognosis. We investigated whether TUBB3 overexpression elicited... 
BETA-TUBULIN | OVEREXPRESSION | ONCOLOGY | RESISTANCE
Journal Article
Cardiovascular Research, ISSN 0008-6363, 02/2019, Volume 115, Issue 2, pp. 258 - 260
Journal Article
Bone, ISSN 8756-3282, 10/2015, Volume 79, pp. 150 - 161
Patients suffering from the rare hereditary disease hypophosphatasia (HPP), which is based on mutations in the ALPL gene, tend to develop central nervous... 
Cellular processes | Overexpression | MAP2 | Transgenic | Hypophosphatasia
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2018, Volume 46, Issue D1, pp. D380 - D386
Abstract Transcription factors (TFs) are major trans-acting factors in transcriptional regulation. Therefore, elucidating TF-target interactions is a key step... 
CELL LUNG-CANCER | OVEREXPRESSION | PROLIFERATION | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | Database Issue
Journal Article
Molecular cancer research : MCR, ISSN 1541-7786, 05/2019, Volume 17, Issue 7, pp. 1429 - 1434
Napabucasin is an NQO1-bioactivatable small molecule hypothesized to affect multiple oncogenic pathways. In a prespecified, retrospective analysis of the... 
OVEREXPRESSION | OXIDOREDUCTASE 1 NQO1 | ONCOLOGY | CANCER | EXPRESSION | CELL BIOLOGY
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 01/2014, Volume 55, Issue 1, pp. 23 - 29
Women with human epidermal growth factor receptor 2 (HER2)positive breast cancer are candidates for treatment with the antiHER2 antibody trastuzumab.... 
OVEREXPRESSION | LOCALIZATION | AMPLIFICATION | TRASTUZUMAB | breast cancer | ANTIBODY | HER2 | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Cu-64-labeled trastuzumab
Journal Article
Molecular Human Reproduction, ISSN 1360-9947, 11/2018, Volume 24, Issue 11, pp. 556 - 563
STUDY QUESTION: Can the mediator complex subunit 12 (MED12) mutation and high mobility group AT-hook 2 (HMGA2) overexpression co-occurrence be explained by the... 
microRNA | Uterine leiomyomas | HMGA2 overexpression | MED12 mutation | MIGRATION | PATHWAYS | CELL-PROLIFERATION | LET-7 | DEVELOPMENTAL BIOLOGY | CANCER | OBSTETRICS & GYNECOLOGY | PATHOGENESIS | OVEREXPRESSION | INVASION | REPRODUCTIVE BIOLOGY | GENE | GROWTH
Journal Article
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