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1. Full Text Molecular evolution and functional characterization of Drosophila insulin-like peptides
by Grönke, Sebastian and Clarke, David-Francis and Broughton, Susan and Andrews, T. Daniel and Partridge, Linda
PLoS Genetics, ISSN 1553-7390, 02/2010, Volume 6, Issue 2, p. e1000857
Multicellular animals match costly activities, such as growth and reproduction, to the environment through nutrient-sensing pathways. The insulin/IGF signaling... 
LIFE-SPAN EXTENSION | SYSTEM | CELLS | CAENORHABDITIS-ELEGANS | GROWTH | GENETICS & HEREDITY | GENETIC REDUNDANCY | RECEPTOR | DIETARY RESTRICTION | EXPRESSION | FLIES | Drosophila - drug effects | Longevity - drug effects | Genetic Loci - genetics | Body Weight - drug effects | Phylogeny | Drosophila Proteins - metabolism | Xenobiotics - pharmacology | Time Factors | Fertility - drug effects | Stress, Physiological - drug effects | Energy Metabolism - genetics | Drosophila - genetics | Stress, Physiological - genetics | Gene Expression Regulation, Developmental - drug effects | Wolbachia - metabolism | Drug Resistance - drug effects | Mutation - genetics | Drosophila - microbiology | Ovum - cytology | Ovum - drug effects | Animals | Diet | Survival Analysis | Drosophila - growth & development | Drosophila Proteins - genetics | Energy Metabolism - drug effects | Evolution, Molecular | Evolutionary biology | Molecular genetics | Drosophila | Amino acids | Genetic aspects | Research | Properties | Peptide hormones | Genetics | Insects | Peptides | Genes | Genomics
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2. Full Text Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells
by Barrios, Florencia and Filipponi, Doria and Pellegrini, Manuela and Paronetto, Maria Paola and Di Siena, Sara and Geremia, Raffaele and Rossi, Pellegrino and De Felici, Massimo and Jannini, Emmanuele A and Dolci, Susanna
Journal of Cell Science, ISSN 0021-9533, 03/2010, Volume 123, Issue 6, pp. 871 - 880
In the mouse, three genes that are homologous to the Drosophila Nanos (Nos) gene have been identified. Deletion of one of these genes, Nanos2, results in male... 
NANOS2 | Taf7l | FGF9 | Spermatogenesis | Meiosis | Gata2 | RA | RNA | INITIATION | SPERMATOGONIAL STEM-CELLS | BINDING PROTEIN TIAR | MICE LACKING | TRANSLATIONAL CONTROL | CELL BIOLOGY | GENE | DIFFERENTIATION | PROMOTES | Testis - metabolism | Germ Cells - drug effects | Fetus - metabolism | Male | RNA-Binding Proteins | Spermatozoa - metabolism | RNA, Messenger - metabolism | Testis - drug effects | Meiosis - drug effects | Protein Binding - drug effects | Female | Germ Cells - cytology | Germ Cells - metabolism | Tretinoin - pharmacology | Animals, Newborn | Testis - cytology | RNA, Messenger - genetics | Gene Expression Regulation, Developmental - drug effects | Ribonucleoproteins - metabolism | Down-Regulation - drug effects | Spermatozoa - drug effects | Fibroblast Growth Factor 9 - pharmacology | Fetus - cytology | Fetus - drug effects | Ovum - cytology | Ovum - drug effects | Up-Regulation - drug effects | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Polyribosomes - metabolism | Mice | Spermatozoa - cytology | Polyribosomes - drug effects | Ovum - metabolism
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3. Full Text Copper Oxide and Zinc Oxide Nanomaterials Act as Inhibitors of Multidrug Resistance Transport in Sea Urchin Embryos: Their Role as Chemosensitizers
by Wu, Bing and Torres-Duarte, Cristina and Cole, Bryan J and Cherr, Gary N
Environmental Science & Technology, ISSN 0013-936X, 05/2015, Volume 49, Issue 9, pp. 5760 - 5770
The ability of engineered nanomaterials (NMs) to act as inhibitors of ATP-binding cassette (ABC) efflux transporters in embryos of white sea urchin (Lytechinus... 
ENVIRONMENTAL SCIENCES | ENGINEERING, ENVIRONMENTAL | ZNO NANOPARTICLES | MULTIXENOBIOTIC RESISTANCE | INTRACELLULAR PH | DAPHNIA-MAGNA | TOXICITY | ACCUMULATION | GLYCOPROTEIN | CUO | CALCEIN-AM | EXPOSURE | Vinblastine - toxicity | Reactive Oxygen Species - metabolism | Cross-Linking Reagents - pharmacology | Drug Resistance, Multiple - drug effects | Fluoresceins - metabolism | Cleavage Stage, Ovum - drug effects | Embryo, Nonmammalian - metabolism | Solubility | Zinc Oxide - toxicity | Sea Urchins - embryology | Sea Urchins - drug effects | Membrane Potential, Mitochondrial - drug effects | Embryo, Nonmammalian - drug effects | Animals | Fertilization - drug effects | Intracellular Space - metabolism | Copper - metabolism | Biological Transport - drug effects | Oxidative Stress - drug effects | Copper - toxicity | Nanostructures - toxicity | Index Medicus
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4. Full Text MAPK/ERK activity is required for the successful progression of mitosis in sea urchin embryos
by Mulner-Lorillon, Odile and Chassé, Héloïse and Morales, Julia and Bellé, Robert and Cormier, Patrick
Developmental Biology, ISSN 0012-1606, 01/2017, Volume 421, Issue 2, pp. 194 - 203
Using sea urchin embryos, we demonstrate that the MEK/MAPK/ERK cascade is essential for the proper progression of the cell cycle. Activation of a limited... 
Cell cycle checkpoint | Embryonic cell division | MAPK/ERK pathway | ACTIVATION | FERTILIZATION | MAP KINASE | STARFISH EGGS | DEVELOPMENTAL BIOLOGY | PROTEIN-KINASES | DNA-REPLICATION | OOCYTE MATURATION | PATHWAY | CALCIUM | CELL-CYCLE | Chromatin - metabolism | Embryo, Nonmammalian - cytology | Nitriles - pharmacology | DNA Replication - drug effects | Sea Urchins - embryology | Sea Urchins - drug effects | Embryo, Nonmammalian - drug effects | CDC2 Protein Kinase - metabolism | Microtubules - metabolism | Microtubules - drug effects | Fertilization - drug effects | Phosphorylation - drug effects | Butadienes - pharmacology | Sea Urchins - cytology | Enzyme Activation - drug effects | Cell Division - drug effects | Biological Evolution | Ovum - cytology | Ovum - drug effects | Animals | Carrier Proteins - metabolism | Embryo, Nonmammalian - enzymology | MAP Kinase Signaling System - drug effects | Mitosis - drug effects | Cyclin B - metabolism | Protein Biosynthesis - drug effects | Embryonic development | Protein biosynthesis | DNA replication | Chromatin | Analysis | Life Sciences | Development Biology
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5. Full Text Assessing the Effects of Aedes aegypti kdr Mutations on Pyrethroid Resistance and Its Fitness Cost
by Brito, Luiz Paulo and Linss, Jutta G. B and Lima-Camara, Tamara N and Belinato, Thiago A and Peixoto, Alexandre A and Lima, José Bento P and Valle, Denise and Martins, Ademir J
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e60878
Pyrethroids are the most used insecticide class worldwide. They target the voltage gated sodium channel (Na-V), inducing the knockdown effect. In Aedes... 
DIPTERA | SODIUM-CHANNEL GENE | INSECTICIDE RESISTANCE | MULTIDISCIPLINARY SCIENCES | FRENCH-WEST-INDIES | RIO-DE-JANEIRO | LIFE-HISTORY | POPULATIONS | CULICIDAE | ANOPHELES-GAMBIAE | MOSQUITO CULEX-PIPIENS | Pyrethrins | Longevity - drug effects | Motor Activity - drug effects | Insecticides | Male | Fertility - genetics | Larva - drug effects | Larva - growth & development | Fertility - drug effects | Female | Pupa - growth & development | Insemination - drug effects | Aedes - physiology | Voltage-Gated Sodium Channels - genetics | Gene Frequency | Circadian Rhythm - genetics | Pupa - drug effects | Aedes - drug effects | Longevity - genetics | Aedes - genetics | Ovum - drug effects | Drug Resistance - genetics | Homozygote | Motor Activity - genetics | Animals | Mutation | Circadian Rhythm - drug effects | Insemination - genetics | Aedes - growth & development | Animal Feed | Economic aspects | Enzymes | Genetic aspects | Gene mutations | Analysis | Vector-borne diseases | Larvae | Disease | Laboratories | Dengue | Parents | Pyrethroids | Aquatic insects | Population genetics | Eggs | Tropical diseases | Mosquitoes | Insecticide resistance | Sodium | Gene frequency | Alleles | Sodium channels (voltage-gated) | Adults | Females | Larval development | Locomotor activity | Fitness
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6. Full Text In utero bisphenol A exposure disrupts germ cell nest breakdown and reduces fertility with age in the mouse
by Wang, Wei and Hafner, Katlyn S and Flaws, Jodi A
Toxicology and Applied Pharmacology, ISSN 0041-008X, 04/2014, Volume 276, Issue 2, pp. 157 - 164
Bisphenol A (BPA) is a known reproductive toxicant in rodents. However, the effects of BPA exposure on early ovarian development and the consequences of such... 
Follicle | Ovary | Bisphenol A | Germ cell nest breakdown | Fertility | Apoptosis | PRENATAL EXPOSURE | VIVO | REPRODUCTIVE HEALTH | PRIMORDIAL FOLLICLE | ENDOCRINE DISRUPTORS | EARLY OOGENESIS | PHARMACOLOGY & PHARMACY | MICE | TOXICOLOGY | DEVELOPMENTAL EXPOSURE | Ovary - pathology | Apoptosis - drug effects | Benzhydryl Compounds - toxicity | Phenols - toxicity | Body Weight - drug effects | Male | Sexual Maturation - drug effects | Fetus - drug effects | Ovum - drug effects | Animals | Aging | Fertility - drug effects | Female | Ovary - drug effects | Mice | Estrus - drug effects | Bisphenol-A | Phenols | Hormones, Sex | Index Medicus | APOPTOSIS | FEMALES | COMPARATIVE EVALUATIONS | PROGENY | 60 APPLIED LIFE SCIENCES | FERTILITY | NESTS | DOSES | GERM CELLS | GENES | OVARIES | BREEDING | CORN OIL | MORPHOLOGY | REPRODUCTION | VITAMIN E | apoptosis | ovary | bisphenol A | follicle | germ cell nest breakdown | fertility
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7. Full Text Assessment of physiological sublethal effects of imidacloprid on the mirid bug Apolygus lucorum (Meyer-Dür)
by Tan, Yao and Biondi, Antonio and Desneux, Nicolas and Gao, Xi-Wu
Ecotoxicology, ISSN 0963-9292, 10/2012, Volume 21, Issue 7, pp. 1989 - 1997
Apolygus lucorum (Meyer-Dür) (Hemiptera: Miridae) is currently one of major mirid pests in the Yangtze River and the Yellow River regions in China.... 
Environment, general | Embryogenesis | Ecotoxicology | Environment | Ecology | Hormesis | Longevity | Fecundity | Environmental Management | GREEN PEACH APHID | NILAPARVATA-LUGENS | SEASONAL ABUNDANCE | PARASITIC WASP | COTTON PEST-MANAGEMENT | ENVIRONMENTAL SCIENCES | MULTISTEP BIOASSAY | HEMIPTERA-MIRIDAE | ECOLOGY | TOXICOLOGY | BT COTTON | MYZUS-PERSICAE | LEARNING PERFORMANCES | Longevity - drug effects | Neonicotinoids | Insecticides | Male | Dose-Response Relationship, Drug | Ovum - drug effects | Animals | Imidazoles | Nitro Compounds | Fertility - drug effects | Oviposition - drug effects | Female | Insecticide Resistance - drug effects | Embryonic Development - drug effects | Hemiptera | Index Medicus
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8. Full Text Effect of Nanoparticles on the Biochemical and Behavioral Aging Phenotype of the Nematode Caenorhabditis elegans
by Scharf, Andrea and Piechulek, Annette and von Mikecz, Anna
ACS Nano, ISSN 1936-0851, 12/2013, Volume 7, Issue 12, pp. 10695 - 10703
Invertebrate animal models such as the nematode Caenorhabditis elegans (C. elegans) are increasingly used in nanotechnological applications. Research in this... 
amyloid | pharyngeal pumping | protein aggregation | silica | nanotechnology | nucleolus | aging | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | TOXICITY | CHEMISTRY, MULTIDISCIPLINARY | SILVER NANOPARTICLES | QUANTUM DOTS | ECOTOXICITY | IN-VIVO | C-ELEGANS | SEROTONIN | MOLECULAR-MECHANISMS | Intestines - drug effects | Hermaphroditic Organisms | Nanoparticles - chemistry | Aging - drug effects | Silver - chemistry | Ubiquitin - chemistry | Homeostasis | Male | Amyloid - chemistry | Spermatozoa - drug effects | Polystyrenes - chemistry | Ovum - drug effects | Particle Size | Phenotype | Animals | Caenorhabditis elegans - drug effects | Cell Nucleolus - metabolism | Behavior, Animal - drug effects | Female | Cell Nucleus - drug effects | Pharynx - drug effects | Proteins | Nanoparticles | Polystyrene resins | Silver | Aging (artificial) | Nematodes | Nanostructure | Worms | Silicon dioxide
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9. Full Text Investigation of the mechanisms by which the molecular chaperone HSPA2 regulates the expression of sperm surface receptors involved in human sperm-oocyte recognition
by Redgrove, Kate A and Anderson, Amanda L and McLaughlin, Eileen A and O'Bryan, Moira K and Aitken, R. John and Nixon, Brett
Molecular Human Reproduction, ISSN 1360-9947, 03/2013, Volume 19, Issue 3, pp. 120 - 135
A unique characteristic of mammalian spermatozoa is that, upon ejaculation, they are unable to recognize and bind to an ovulated oocyte. These functional... 
Capacitation | Spermatozoa | Hspa2 | Zona pellucida | Molecular chaperone | Sperm Capacitation - genetics | Sperm Head - drug effects | Cell Adhesion Molecules - genetics | Hyaluronoglucosaminidase - metabolism | Humans | Sperm-Ovum Interactions - genetics | Male | Protein Transport - drug effects | Oocytes - cytology | Oocytes - drug effects | Female | Sperm Head - metabolism | Sperm-Ovum Interactions - drug effects | Oocytes - metabolism | Cells, Cultured | Gene Expression Regulation, Developmental - drug effects | HSP70 Heat-Shock Proteins - genetics | Cell Adhesion Molecules - metabolism | HSP70 Heat-Shock Proteins - metabolism | Signal Transduction - drug effects | Membrane Microdomains - drug effects | Sperm Capacitation - drug effects | Zona Pellucida - metabolism | Cholesterol - pharmacology | Protein Kinase Inhibitors - pharmacology | Zona Pellucida - drug effects | Cerebroside-Sulfatase - metabolism | Hyaluronoglucosaminidase - genetics | Cerebroside-Sulfatase - genetics
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10. Full Text Integrating multiple stressors across life stages and latitudes: Combined and delayed effects of an egg heat wave and larval pesticide exposure in a damselfly
by Sniegula, Szymon and Janssens, Lizanne and Stoks, Robby
Aquatic Toxicology, ISSN 0166-445X, 05/2017, Volume 186, pp. 113 - 122
To understand the effects of pollutants in a changing world we need multistressor studies that combine pollutants with other stressors associated with global... 
Pyrethroids | Life history | Carry-over effects | CTmax | Heat wave | Latitudinal gradient | HIGH-TEMPERATURES | CLIMATE-CHANGE | ODONATA | TIME | DEVELOPMENTAL RATE | HISTORY PLASTICITY | THERMAL TOLERANCE | PHOTOPERIOD | MARINE & FRESHWATER BIOLOGY | TOXICOLOGY | RISK-ASSESSMENT | REPRODUCTION | Heat-Shock Response - drug effects | Odonata - growth & development | Muscles - physiology | Odonata - physiology | Male | Environmental Exposure - analysis | Hot Temperature | Life Cycle Stages | Ovum - drug effects | Organ Size - drug effects | Animals | Flight, Animal - drug effects | Larva - drug effects | Models, Biological | Ovum - physiology | Pesticides - toxicity | Muscles - drug effects | Female | Stress, Physiological - drug effects | Odonata - drug effects | Analysis | Pesticides | Nature conservation | Physiological aspects | Pollutants | Index Medicus
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11. Full Text Effects of Glyphosate and its Formulation, Roundup, on Reproduction in Zebrafish (Danio rerio)
by Uren Webster, Tamsyn M and Laing, Lauren V and Florance, Hannah and Santos, Eduarda M
Environmental Science & Technology, ISSN 0013-936X, 01/2014, Volume 48, Issue 2, pp. 1271 - 1279
Roundup and its active ingredient glyphosate are among the most widely used herbicides worldwide and may contaminate surface waters. Research suggests both... 
ENVIRONMENTAL SCIENCES | ENGINEERING, ENVIRONMENTAL | SUBLETHAL CONCENTRATION | DNA-DAMAGE | ESTROGEN | HERBICIDE GLYPHOSATE | TOXICITY | PARAMETERS | ATRAZINE | SHORT-TERM EXPOSURE | SURFACE WATERS | PESTICIDES | Glycine - analogs & derivatives | Zebrafish - anatomy & histology | Oxidative Stress | RNA, Messenger - genetics | Gonads - drug effects | Male | Gene Expression Profiling | Herbicides - toxicity | RNA, Messenger - metabolism | Zebrafish - embryology | Embryo, Nonmammalian - drug effects | Zebrafish - genetics | Ovum - drug effects | Reproduction - drug effects | Gonads - cytology | Gonads - metabolism | Animals | Glycine - toxicity | Water - chemistry | Zebrafish - physiology | Female | Ovary - drug effects | Embryo, Nonmammalian - physiology | Ovum - metabolism | Index Medicus
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12. Full Text Glyphosate-Based Herbicides Produce Teratogenic Effects on Vertebrates by Impairing Retinoic Acid Signaling
by Paganelli, Alejandra and Gnazzo, Victoria and Acosta, Helena and López, Silvia L and Carrasco, Andrés E
Chemical Research in Toxicology, ISSN 0893-228X, 10/2010, Volume 23, Issue 10, pp. 1586 - 1595
The broad spectrum herbicide glyphosate is widely used in agriculture worldwide. There has been ongoing controversy regarding the possible adverse effects of... 
CHEMISTRY, MEDICINAL | MOUSE EMBRYOGENESIS | XENOPUS-LAEVIS EMBRYOS | POSTERIOR AXIS | CHEMISTRY, MULTIDISCIPLINARY | PRIMARY NEUROGENESIS | CRANIAL NEURAL CREST | GENE-EXPRESSION | CENTRAL-NERVOUS-SYSTEM | TOXICOLOGY | CYTOGENETIC TESTS | ZEBRAFISH EMBRYO | SONIC-HEDGEHOG | Glycine - analogs & derivatives | Otx Transcription Factors - antagonists & inhibitors | Herbicides - chemistry | Humans | Soil Pollutants - chemistry | Hedgehog Proteins - metabolism | Otx Transcription Factors - metabolism | Neurons - cytology | Neurogenesis | Soil Pollutants - toxicity | Glycine - toxicity | Glycine - chemistry | Tretinoin - metabolism | Oocytes - drug effects | Neurons - metabolism | Xenopus laevis - growth & development | Neurons - drug effects | Oocytes - metabolism | Herbicides - toxicity | Chick Embryo | Ovum - drug effects | Animals | Signal Transduction - drug effects | Xenopus laevis - metabolism | Ovum - metabolism | Index Medicus
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13. Full Text Effect of insecticide resistance on development, longevity and reproduction of field or laboratory selected aedes aegypti populations
by Martins, Ademir Jesus and Ribeiro, Camila Dutra e Mello and Bellinato, Diogo Fernandes and Peixoto, Alexandre Afranio and Valle, Denise and Lima, José Bento Pereira
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e31889
Aedes aegypti dispersion is the major reason for the increase in dengue transmission in South America. In Brazil, control of this mosquito strongly relies on... 
FITNESS | HCH DIELDRIN RESISTANT | DIPTERA | FEMALE ANOPHELES-GAMBIAE | MULTIDISCIPLINARY SCIENCES | PYRETHROID RESISTANCE | PERMETHRIN | AN-STEPHENSI MOSQUITOS | DELTAMETHRIN RESISTANCE | INHERITANCE | LEPIDOPTERA | Aedes - physiology | Geography | Pyrethrins - toxicity | Laboratories | Longevity - drug effects | Selection, Genetic | Body Weight - drug effects | Insecticide Resistance - genetics | Aedes - drug effects | Phylogeny | Aedes - genetics | Feeding Behavior - drug effects | Ovum - drug effects | Reproduction - drug effects | Animals | Genetic Fitness | Time Factors | Ovum - physiology | Oviposition - drug effects | Female | Insecticide Resistance - drug effects | Longevity - physiology | Organophosphates - toxicity | Aedes - growth & development | Pesticide resistance | Larvae | Populations | Pyrethroids | Insecticides | Parasites | Aquatic insects | Eggs | Organophosphates | Insecticide resistance | Population | Behavior | Deltamethrin | Vector-borne diseases | Natural populations | Dengue | Longevity | Disease control | Biological activity | Environmental conditions | Corrosion resistance | Sex ratio | Dynamic tests | Mosquitoes | Insects | Adults | Females | Viability | Larval development | Fitness
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