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oxazepines - chemical synthesis (91) 91
index medicus (88) 88
oxazepines - chemistry (83) 83
chemistry, organic (82) 82
oxazepines - pharmacology (80) 80
animals (71) 71
chemistry, medicinal (57) 57
humans (53) 53
molecular structure (52) 52
derivatives (44) 44
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mice (36) 36
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oxazepines (30) 30
pharmacology & pharmacy (29) 29
cyclization (27) 27
stereoisomerism (27) 27
chemistry (24) 24
chemistry, multidisciplinary (24) 24
catalysis (23) 23
thiazepines (22) 22
female (21) 21
models, molecular (21) 21
oxazepine (21) 21
biochemistry & molecular biology (20) 20
cell line, tumor (20) 20
analysis (19) 19
potent (18) 18
azepines - chemical synthesis (17) 17
dose-response relationship, drug (17) 17
antineoplastic agents - pharmacology (16) 16
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enzyme inhibitors - pharmacology (16) 16
inhibitors (16) 16
thiazepines - chemical synthesis (15) 15
thiazepines - pharmacology (13) 13
apoptosis - drug effects (12) 12
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antineoplastic agents - chemical synthesis (11) 11
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organic chemistry (10) 10
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antineoplastic agents - chemistry (9) 9
chemical phenomena (9) 9
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farnesyl-diphosphate farnesyltransferase - antagonists & inhibitors (9) 9
heterocycles (9) 9
in vitro techniques (9) 9
inhibition (9) 9
inhibitory concentration 50 (9) 9
molecular conformation (9) 9
activation (8) 8
analogs (8) 8
cell line (8) 8
chemistry, inorganic & nuclear (8) 8
crystallography, x-ray (8) 8
discovery (8) 8
drug evaluation, preclinical (8) 8
oxazepines - therapeutic use (8) 8
pyrroles - pharmacology (8) 8
rats, wistar (8) 8
strategy (8) 8
2-aminothiophenol (7) 7
alkynes - chemistry (7) 7
anticonvulsants - chemical synthesis (7) 7
article (7) 7
azepines - chemistry (7) 7
benzodiazepines - chemical synthesis (7) 7
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cancer (7) 7
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chemical properties (7) 7
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chemistry, applied (7) 7
heterocyclic compounds - chemical synthesis (7) 7
magnetic resonance spectroscopy (7) 7
microwaves (7) 7
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2,3-dihydro-2,4-diphenyl-1,5-benzothiazepines (6) 6
amino acids (6) 6
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antipsychotic agents - chemical synthesis (6) 6
antipsychotic agents - pharmacology (6) 6
cell survival - drug effects (6) 6
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disease models, animal (6) 6
drug discovery (6) 6
drug screening assays, antitumor (6) 6
heterocyclic compounds (6) 6
hydrazines - pharmacology (6) 6
in-vitro (6) 6
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Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2012, Volume 55, Issue 4, pp. 1572 - 1582
A series of new pyridobenzoxazepine derivatives with various heterocyclic amine side chains were synthesized to explore two main parameters related to the... 
NOREPINEPHRINE REUPTAKE | GLUTAMATE RECEPTORS | CHEMISTRY, MEDICINAL | ATYPICAL ANTIPSYCHOTIC ACTIVITY | DOPAMINE RELEASE | PYRIDOBENZODIAZEPINE DERIVATIVES | N-DESMETHYLCLOZAPINE | PROTEIN-COUPLED RECEPTORS | DISCRIMINATIVE STIMULUS | MAJOR METABOLITE | PREFRONTAL CORTEX | Brain - anatomy & histology | Cricetulus | Pyridines - chemistry | Receptors, Dopamine D4 - agonists | Serotonin 5-HT1 Receptor Antagonists - pharmacology | Humans | Receptors, Adrenergic, alpha-2 - metabolism | Serotonin 5-HT1 Receptor Agonists - pharmacology | Male | Piperazines - chemistry | Structure-Activity Relationship | Receptors, Dopamine D2 - metabolism | Antipsychotic Agents - chemical synthesis | Brain - metabolism | Serotonin 5-HT1 Receptor Antagonists - chemical synthesis | Oxazepines - chemical synthesis | Serotonin 5-HT1 Receptor Agonists - chemistry | Radioligand Assay | Serotonin 5-HT1 Receptor Antagonists - chemistry | Receptor, Serotonin, 5-HT1A - metabolism | CHO Cells | Cricetinae | Receptors, Dopamine D2 - agonists | Pyridines - chemical synthesis | Models, Molecular | Rats | Serotonin 5-HT1 Receptor Agonists - chemical synthesis | Organ Specificity | Piperazines - pharmacology | Rats, Sprague-Dawley | Oxazepines - pharmacology | Brain - drug effects | Animals | Antipsychotic Agents - chemistry | Piperazines - chemical synthesis | Receptors, Dopamine D4 - metabolism | Pyridines - pharmacology | Antipsychotic Agents - pharmacology | In Vitro Techniques | Receptor, Serotonin, 5-HT2A - metabolism | Oxazepines - chemistry
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2011, Volume 133, Issue 36, pp. 14228 - 14231
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2016, Volume 59, Issue 5, pp. 2163 - 2178
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 01/2017, Volume 60, Issue 2, pp. 627 - 640
Journal Article
Chemical Communications, ISSN 1359-7345, 01/2013, Volume 49, Issue 7, pp. 701 - 703
A highly efficient protocol of copper catalysis for the one-pot synthesis of fused dibenzo[b,f][1,4]oxazepines is reported. The transformation involves a... 
1,3-DIPOLAR CYCLOADDITION | ARYLATION | SC-51089 | DIACYLHYDRAZINE | ULLMANN | BROMIDES | CHEMISTRY, MULTIDISCIPLINARY | ARYL CHLORIDES | Catalysis | Copper | Oxazepines - chemical synthesis | Stereoisomerism | Synthesis | Methodology | Aromatic compounds | Chlorides | Transformations
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2013, Volume 56, Issue 11, pp. 4597 - 4610
Journal Article
Chemical Communications, ISSN 1359-7345, 2011, Volume 47, Issue 27, pp. 7845 - 7847
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 08/2014, Volume 79, Issue 16, pp. 7696 - 7702
Journal Article
Organic Letters, ISSN 1523-7060, 06/2015, Volume 17, Issue 11, pp. 2680 - 2683
Journal Article
Journal Article
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