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female (75) 75
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adjuvants, immunologic - toxicity (23) 23
cell biology (21) 21
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activation (20) 20
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administration, topical (18) 18
atopic-dermatitis (18) 18
contact hypersensitivity (18) 18
dermatitis (18) 18
lymph nodes - drug effects (18) 18
oxazolone - pharmacology (18) 18
rodents (18) 18
allergens - toxicity (17) 17
biochemistry (17) 17
colitis (17) 17
cytokines (17) 17
dermatitis, allergic contact - immunology (17) 17
ulcerative-colitis (17) 17
cells (16) 16
colitis - chemically induced (16) 16
dendritic cells (16) 16
dermatitis, contact - etiology (16) 16
dose-response relationship, drug (16) 16
edema - chemically induced (16) 16
allergens (15) 15
dermatitis, allergic contact - pathology (15) 15
oxazolone - administration & dosage (15) 15
abridged index medicus (14) 14
molecular biology (14) 14
t-cells (14) 14
cells, cultured (13) 13
chemistry, medicinal (13) 13
irritants - toxicity (13) 13
skin - pathology (13) 13
contact dermatitis (12) 12
delayed-type hypersensitivity (12) 12
dermatitis, contact - drug therapy (12) 12
hypersensitivity (12) 12
hypersensitivity, delayed - immunology (12) 12
immune-responses (12) 12
lymph nodes - immunology (12) 12
lymph nodes - pathology (12) 12
t-lymphocytes - immunology (12) 12
allergy (11) 11
animal models (11) 11
biochemistry & molecular biology (11) 11
chemistry, multidisciplinary (11) 11
dinitrochlorobenzene - toxicity (11) 11
gene expression (11) 11
local lymph node assay (11) 11
mice, hairless (11) 11
research article (11) 11
crohns-disease (10) 10
dinitrofluorobenzene - toxicity (10) 10
epidermis - immunology (10) 10
in-vivo (10) 10
inflammatory bowel disease (10) 10
inflammatory-bowel-disease (10) 10
keratinocytes (10) 10
oxazolone colitis (10) 10
proteins (10) 10
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cancer (9) 9
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cytokines - metabolism (9) 9
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epidermis - pathology (9) 9
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Nature Protocols, ISSN 1754-2189, 03/2007, Volume 2, Issue 3, pp. 541 - 546
Journal Article
Journal Article
Bioorganic Chemistry, ISSN 0045-2068, 04/2019, Volume 85, pp. 431 - 444
In this research paper, a stepwise chemical reaction was conducted to synthesize and develop of a new potent azo-oxazolone, which was used as prototypical... 
Characterization | Antimicrobial | Synthesis | Antioxidant power, wound healing | Acute toxicity | DESIGN | DYES | ANALOGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | OXAZOLONE | GFP | SPECTROSCOPIC CHARACTERIZATION | BIOLOGICAL EVALUATION | CHALCONE | IMIDAZOLINONES | Antioxidants | Care and treatment | Chemical properties | Wounds and injuries | Analysis
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2018, Volume 41, Issue 2, pp. 259 - 265
Juniperus chinensis, commonly Chinese juniper, has been used for treating inflammatory diseases. This study aimed to investigate anti-atopic dermatitis (AD)... 
atopic dermatitis | transepidermal water loss | interleukin 4 | immunoglobulin E | Juniperus chinensis fruit | skin hydration | Immunoglobulin E | Interleukin 4 | Transepidermal water loss | Atopic dermatitis | Skin hydration | NATURAL-PRODUCTS | DRUG DISCOVERY | LEAVES | CONTACT HYPERSENSITIVITY | SKIN BARRIER | CHILDREN | HAIRLESS MOUSE | BERRIES | DISEASE | PHARMACOLOGY & PHARMACY | EXTRACT | Plant Extracts - chemistry | Flavonoids - analysis | Biflavonoids - chemistry | Skin - metabolism | Juniperus - chemistry | Oxazolone - toxicity | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Administration, Cutaneous | Dinitrochlorobenzene - toxicity | Flavonoids - therapeutic use | Dermatitis, Atopic - prevention & control | Glycosides - administration & dosage | Plant Extracts - administration & dosage | Dermatitis, Atopic - chemically induced | Dermatitis, Atopic - immunology | Flavonoids - administration & dosage | Female | Molecular Structure | Phytotherapy | Glycosides - chemistry | Republic of Korea | Skin - pathology | Skin - immunology | Juniperus - growth & development | Glycosides - analysis | Fruit - chemistry | Mice, Hairless | Anti-Inflammatory Agents, Non-Steroidal - analysis | Adjuvants, Immunologic - toxicity | Dermatitis, Atopic - pathology | Irritants - toxicity | Biflavonoids - administration & dosage | Fruit - growth & development | Interleukin-4 - blood | Animals | Immunoglobulin E - analysis | Biflavonoids - analysis | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Biflavonoids - therapeutic use | Mice, Inbred BALB C | Flavonoids - chemistry | Plant Extracts - therapeutic use | Glycosides - therapeutic use | Skin - drug effects | Signs and symptoms | Oxazolone | Ethanol | Leukocytes (eosinophilic) | Medical treatment | Interleukin | Epidermis | Pharmacology | Hairless | Dermatitis | Chemical compounds | Inflammatory diseases | Fruits | Water loss | Skin diseases | Mice | Infiltration | Topical application | Lesions | Thickening | Eosinophils | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2011, Volume 121, Issue 6, pp. 2242 - 2253
Probiotic bacteria can potentially have beneficial effects on the clinical course of several intestinal disorders, but our understanding of probiotic action is... 
MEDICINE, RESEARCH & EXPERIMENTAL | GROWTH-FACTOR RECEPTOR | EPITHELIAL-CELLS | CROHNS-DISEASE | INDUCED APOPTOSIS | SULFATE-INDUCED COLITIS | IMMUNE-RESPONSES | LACTOBACILLUS-GG | ACTIVE ULCERATIVE-COLITIS | PLACEBO-CONTROLLED TRIAL | OXAZOLONE COLITIS | Recombinant Proteins - therapeutic use | Hydrogels | Apoptosis - drug effects | Epithelial Cells - drug effects | Oxazolone - toxicity | Receptor, Epidermal Growth Factor - drug effects | Administration, Rectal | Quinazolines | Probiotics - chemistry | Bacterial Proteins - therapeutic use | Intestinal Mucosa - drug effects | Microspheres | Lactobacillus rhamnosus - chemistry | Colitis - chemically induced | Colitis - drug therapy | Drug Evaluation, Preclinical | Proto-Oncogene Proteins c-akt - metabolism | Receptor, Epidermal Growth Factor - physiology | Permeability - drug effects | Mice, Inbred C57BL | Epithelial Cells - pathology | Tyrphostins - pharmacology | Lactobacillus rhamnosus - physiology | Recombinant Proteins - pharmacology | Enzyme Activation - drug effects | Bacterial Proteins - administration & dosage | Recombinant Proteins - administration & dosage | Dextran Sulfate - toxicity | Bacterial Proteins - pharmacology | Animals | Colitis - enzymology | Signal Transduction - drug effects | Epithelial Cells - enzymology | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Bacterial Proteins - isolation & purification | Colitis - prevention & control | Intestinal Mucosa - pathology | Proto-Oncogene Proteins c-akt - drug effects | Inflammation | Gastrointestinal diseases | Analysis | Apoptosis | Index Medicus | Abridged Index Medicus
Journal Article
Toxicology, ISSN 0300-483X, 2007, Volume 242, Issue 1, pp. 144 - 152
Abstract Animal testing causes ethical problems and in view of EU regulations (e.g. EU-Guideline (76/768/EEC, February 2003)) or REACH the development of... 
Emergency | p38 | Irritant compounds | JNK | Reconstituted skin models | Skin explants | Sensitizing compounds | ERK | INTER-LABORATORY VALIDATION | reconstituted skin models | CHEMOKINE EXPRESSION | ACTIVATED PROTEIN-KINASE | INTEGRATED MODEL | DENDRITIC CELLS | ALTERNATIVE END-POINTS | LYMPH-NODE ASSAY | sensitizing compounds | irritant compounds | IRRITANTS | INFLAMMATION | skin explants | PHARMACOLOGY & PHARMACY | TOXICOLOGY | CONTACT SENSITIZERS | Phosphorylation | Lymph Nodes - pathology | Skin Irritancy Tests | Skin - metabolism | Humans | Oxazolone - toxicity | Irritants - classification | JNK Mitogen-Activated Protein Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Sodium Dodecyl Sulfate - toxicity | Dose-Response Relationship, Drug | Octoxynol - toxicity | STAT1 Transcription Factor - metabolism | Dinitrofluorobenzene - toxicity | Female | Lymph Nodes - drug effects | p38 Mitogen-Activated Protein Kinases - metabolism | Allergens - toxicity | Phospholipase C gamma - metabolism | Tissue Culture Techniques | Allergens - classification | Membranes, Artificial | Mice, Hairless | Irritants - toxicity | Mice, Inbred C3H | Animals | Signal Transduction - drug effects | Mice | Edema - chemically induced | Enzyme Activation | Skin - drug effects | Allergens | Epidermal growth factor | Surface active agents | Analysis | Skin | Transforming growth factors | Sulfates | T cells | Mitogens | Phosphotransferases | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2013, Volume 190, Issue 3, pp. 997 - 1007
Annexin A1 (AnxA1) is recognized as an endogenous anti-inflammatory molecule. However, its effects on the adaptive immune response and, in particular, on T... 
PERIPHERAL-BLOOD LEUKOCYTES | COLLAGEN-INDUCED ARTHRITIS | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | IN-VITRO | ACTIVATION | IMMUNE-RESPONSES | CONTACT HYPERSENSITIVITY | HOST-DEFENSE | IL-17-DEFICIENT MICE | IMMUNOLOGY | EXPRESSION | Annexin A1 - deficiency | Hypersensitivity, Delayed - pathology | Dermatitis, Allergic Contact - immunology | Inflammation - pathology | Lymphokines - secretion | Ovalbumin - immunology | Peptide Fragments - toxicity | Oxazolone - toxicity | Dermatitis, Allergic Contact - pathology | Hypersensitivity, Delayed - immunology | Enzyme Activation - immunology | Arthritis, Experimental - pathology | CD4-Positive T-Lymphocytes - immunology | Oxazolone - immunology | Signal Transduction - immunology | Ovalbumin - toxicity | Lymphokines - genetics | Annexin A1 - immunology | Peptide Fragments - immunology | Lymphokines - biosynthesis | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Specific Pathogen-Free Organisms | Gene Expression Regulation - immunology | Lymphocyte Activation | Mice, Inbred C57BL | Neutrophils - immunology | Interleukin-17 - genetics | Mice, Transgenic | Arthritis, Experimental - immunology | Inflammation - immunology | Interleukin-17 - biosynthesis | Cell Adhesion | Mice, Knockout | Animals | CD4-Positive T-Lymphocytes - secretion | Nuclear Receptor Subfamily 1, Group F, Member 3 - biosynthesis | Mice | CD8-Positive T-Lymphocytes - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 05/2014, Volume 24, Issue 9, pp. 2188 - 2192
-Substituted amino-2(5 ) oxazolones are a novel class of insecticides acting as nicotinic acetylcholine receptor (nAChR) agonists and show potent activity... 
Neonicotinoid | Oxazolone | Insecticide | Acetylcholine receptor | CHEMISTRY, MEDICINAL | CHEMISTRY, ORGANIC | SYSTEMS | Insecticides - chemistry | Receptors, Nicotinic - metabolism | Animals | Amination | Oxazolone - toxicity | Insecta - drug effects | Insecta - physiology | Oxazolone - chemistry | Insecticides - toxicity | Insecticides | Analysis | Index Medicus
Journal Article