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1. Full Text Treatment of diabetic neuropathy and neuropathic pain: how far have we come?
by Ziegler, Dan
Diabetes care, ISSN 0149-5992, 2008, Volume 31, Issue 2, pp. S255 - 261
At least one of four diabetic patients is affected by distal symmetric polyneuropathy, which represents a major health problem, since it may present with... 
PLACEBO | POLYNEUROPATHY | MULTICENTER | NERVE FUNCTION | DULOXETINE | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | PERIPHERAL NEUROPATHY | CONTROLLED-RELEASE OXYCODONE | ALPHA-LIPOIC ACID | RANDOMIZED CONTROLLED-TRIAL | Aldehyde Reductase - antagonists & inhibitors | Diabetic Neuropathies - prevention & control | Humans | Polyneuropathies - epidemiology | Polyneuropathies - prevention & control | Analgesics, Opioid - therapeutic use | Polyneuropathies - drug therapy | Clinical Trials as Topic | Diabetic Neuropathies - drug therapy | Imidazolidines - therapeutic use | Polyneuropathies - physiopathology | Enzyme Inhibitors - therapeutic use | Incidence | Inositol - blood | Diabetic Neuropathies - epidemiology | Sodium Channel Blockers - therapeutic use | Sodium-Potassium-Exchanging ATPase - blood | Diabetic Neuropathies - physiopathology | Medical research | Anticonvulsants | Care and treatment | Pain | Medicine, Experimental | Diabetes | Health aspects | Risk factors | Studies | Side effects | Hospitals | Mortality | Diabetic neuropathy | Clinical medicine | Drug therapy | Foot diseases | Drug use | Quality of life | Fibers
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2. Genetic predisposition to oxcarbazepine induced Stevens-Johnson syndrome
by Wal, Pranay and Wal, Ankita and Pandey, Umeshwar and Rai, Awani K and Bhandari, Anil
12/2011
Stevens-Johnson syndrome (SJS) is a rare immunologic reaction that may involve skin or various mucosal surfaces. The etiology may range from multiple... 
Stevens-Johnson syndrome | oxcarbazepine | Hypersensitivity
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3. Full Text Antiepileptic drugs-induced hyponatremia: Review and analysis of 560 hospitalized patients
by Intravooth, Tassanai and Staack, Anke M and Juerges, Katharina and Stockinger, Jakob and Steinhoff, Bernhard J
Epilepsy Research, ISSN 0920-1211, 07/2018, Volume 143, pp. 7 - 10
Recent evidence suggests that eslicarbazepine acetate (ESL) might be an appropriate alternative to carbamazepine (CBZ) and oxcarbazepine (OXC) due to its... 
Oxcarbazepine | Hyponatremia | Antiepileptic drugs | Elderly patients | Eslicarbazepine acetate | Carbamazepine | OXCARBAZEPINE-INDUCED HYPONATREMIA | THERAPY | PROFILE | EPILEPSY | CLINICAL NEUROLOGY | Hyponatremia - epidemiology | Oxcarbazepine - therapeutic use | Humans | Anticonvulsants - therapeutic use | Carbamazepine - therapeutic use | Male | Hospitalization | Hyponatremia - blood | Dibenzazepines - adverse effects | Epilepsy - epidemiology | Incidence | Oxcarbazepine - adverse effects | Young Adult | Anticonvulsants - adverse effects | Carbamazepine - adverse effects | Dibenzazepines - therapeutic use | Adult | Epilepsy - drug therapy | Female | Aged | Epilepsy - blood | Drugs | Hospital patients | Anticonvulsants | Epilepsy | Medical records
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4. Full Text The effects of oxcarbazepine, levetiracetam, and lamotrigine on semen quality, sexual function, and sex hormones in male adults with epilepsy
by Wu, Dongmei and Chen, Lang and Ji, Fayuan and Si, Yang and Sun, Hongbin
Epilepsia, ISSN 0013-9580, 07/2018, Volume 59, Issue 7, pp. 1344 - 1350
ObjectiveTo investigate the effects of antiepileptic drugs (AEDs; oxcarbazepine [OXC], levetiracetam [LEV], and lamotrigine [LTG]) on semen quality, sexual... 
epilepsy | antiepileptic drugs | sperm | sexual function | hormone | REPRODUCTIVE ENDOCRINE FUNCTION | METABOLISM | STEROIDS | TESTOSTERONE | MEN | DYSFUNCTION | CLINICAL NEUROLOGY | Epilepsy, Tonic-Clonic - drug therapy | Oxcarbazepine - therapeutic use | Epilepsies, Partial - drug therapy | Humans | Semen Analysis | Anticonvulsants - therapeutic use | Male | Lamotrigine - adverse effects | Gonadal Steroid Hormones - blood | Marital Status | Anticonvulsants - pharmacology | Levetiracetam - therapeutic use | Lamotrigine - therapeutic use | Levetiracetam - adverse effects | Oxcarbazepine - adverse effects | Lamotrigine - pharmacology | Anticonvulsants - adverse effects | Epilepsy, Generalized - drug therapy | Levetiracetam - pharmacology | Fertility - drug effects | Adult | Oxcarbazepine - pharmacology | Adults | Hormones, Sex | Sexual disorders | Analysis | Epilepsy | Statistical analysis | Sperm | Semen | Sex | Hormones | Antiepileptic agents | Survival | Patients | Etiracetam | Oxcarbazepine | Sex hormones | Ejaculation | Health risk assessment | Lamotrigine
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5. Full Text Population pharmacokinetics of oxcarbazepine active metabolite in Chinese paediatric epilepsy patients and its application in individualised dosage regimens
by Lin, Wei-wei and Li, Xi-wen and Jiao, Zheng and Zhang, Jin and Rao, Xin and Zeng, Da-yong and Lin, Xin-hua and Wang, Chang-lian
European Journal of Clinical Pharmacology, ISSN 0031-6970, 03/2019, Volume 75, Issue 3, pp. 381 - 392
PurposeOxcarbazepine (OXC) is an antiepileptic drug metabolised to active 10-monohydroxy derivative (MHD) following oral administration. There are no MHD... 
Oxcarbazepine | Population pharmacokinetics | Paediatric patient | Epileptic | Individualise | CLEARANCE | DRUG-INTERACTIONS | CARBAMAZEPINE | VALPROIC ACID | CLINICAL PHARMACOKINETICS | GENE POLYMORPHISMS | CHILDREN | PREDICTION | INFANTS | RESISTANCE | PHARMACOLOGY & PHARMACY | Anticonvulsants - pharmacokinetics | Oxcarbazepine - therapeutic use | Prospective Studies | Carbamazepine - analogs & derivatives | Humans | Anticonvulsants - therapeutic use | Epilepsy - metabolism | Genotype | Male | Oxcarbazepine - blood | Glucuronosyltransferase - genetics | Asian Continental Ancestry Group | Models, Biological | Epilepsy - drug therapy | Epilepsy - genetics | Female | ATP Binding Cassette Transporter, Subfamily B - genetics | Polymorphism, Single Nucleotide | Oxcarbazepine - pharmacokinetics | Child | Carbamazepine - blood | ATP Binding Cassette Transporter, Subfamily B, Member 2 - genetics | Medical research | Enzymes | Medical colleges | Metabolites | Healthcare industry software | Epilepsy | Medicine, Experimental | Single nucleotide polymorphisms | Chromosomes | Dosing | Immunoassay | Magnetohydrodynamics | Body weight | Oral administration | Data processing | Pharmacology | Single-nucleotide polymorphism | Antiepileptic agents | Dosage | Gene polymorphism | Patients | Mathematical models | Genetic factors | Pharmacokinetics | Bayesian analysis | Polymorphism | Index Medicus
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6. Full Text Comparison of oxcarbazepine efficacy and MHD concentrations relative to age and BMI: Associations among ABCB1, ABCC2, UGT2B7, and SCN2A polymorphisms
by Yang, Xue and Yan, Yuanliang and Fang, Shu and Zeng, Shuangshuang and Ma, Hongying and Qian, Long and Chen, Xi and Wei, Jie and Gong, Zhicheng and Xu, Zhijie
Medicine, ISSN 0025-7974, 03/2019, Volume 98, Issue 12, p. e14908
Genetic polymorphisms are related to the concentration and efficacy of oxcarbazepine (OXC). 10-Hydroxycarbazepine (MHD) is the major pharmacologically active... 
epilepsy | DEFINITION | POPULATION | ABCB1 | ABCC2 | CARBAMAZEPINE | gene polymorphisms | MEDICINE, GENERAL & INTERNAL | oxcarbazepine | PHARMACOKINETICS | 10-hydroxycarbazepine | RESISTANCE | SCN2A | ANTIEPILEPTIC DRUGS | CHINESE PATIENTS | HNF4-ALPHA | Oxcarbazepine - therapeutic use | Age Factors | Humans | Middle Aged | Child, Preschool | Infant | Male | Young Adult | Glucuronosyltransferase - genetics | China | Adult | Female | Multidrug Resistance-Associated Proteins - genetics | ATP Binding Cassette Transporter, Subfamily B - genetics | Oxcarbazepine - pharmacokinetics | Child | Body Mass Index | Anticonvulsants - pharmacokinetics | Carbamazepine - analogs & derivatives | NAV1.2 Voltage-Gated Sodium Channel - genetics | Anticonvulsants - therapeutic use | Genotype | Asian Continental Ancestry Group | Adolescent | Epilepsy - drug therapy | Polymorphism, Single Nucleotide | Carbamazepine - blood | Body mass index | Usage | Analysis | Epilepsy | Genetic aspects | Drug therapy, Combination | Research | Drug therapy | Genetic polymorphisms
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7. Full Text Evidence-based guideline: Treatment of painful diabetic neuropathy
by Bril, V and England, J and Franklin, GM and Backonja, M and Cohen, J and Del Toro, D and Feldman, E and Iverson, DJ and Perkins, B and Russell, JW and Zochodne, D
NEUROLOGY, ISSN 0028-3878, 05/2011, Volume 76, Issue 20, pp. 1758 - 1765
Objective: To develop a scientifically sound and clinically relevant evidence-based guideline for the treatment of painful diabetic neuropathy (PDN). Methods:... 
OXCARBAZEPINE | PREGABALIN | AMITRIPTYLINE | POSTHERPETIC NEURALGIA | SODIUM VALPROATE | DOUBLE-BLIND | PERIPHERAL NEUROPATHY | RANDOMIZED CONTROLLED-TRIAL | PLACEBO-CONTROLLED TRIAL | CLINICAL NEUROLOGY | SYMPTOMATIC TREATMENT
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8. Formulation development and characterization of oxcarbazepine microemulsion for intranasal delivery
by Tirunagari, Mamatha and Sameen, Jamal and Nandagopal, Anitha
Acta Pharmaceutica Sciencia, ISSN 1307-2080, 2017, Volume 55, Issue 2, pp. 79 - 94
Oxcarbazepine | Intranasal | Microemulsion
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9. Full Text Practice Parameter: The diagnostic evaluation and treatment of trigeminal neuralgia (an evidence-based review) - Report of the quality standards subcommittee of the American academy of and the European federation of neurological societies
by Gronseth, G and Cruccu, G and Alksne, J and Argoff, C and Brainin, M and Burchiel, K and Nurmikko, T and Zakrzewska, JM
NEUROLOGY, ISSN 0028-3878, 10/2008, Volume 71, Issue 15, pp. 1183 - 1190
Background: Trigeminal neuralgia (TN) is a common cause of facial pain. Purpose: To answer the following questions: 1) In patients with TN, how often does... 
BLIND | TRIAL | OXCARBAZEPINE | MULTIPLE-SCLEROSIS | FACIAL-PAIN | VASCULAR COMPRESSION | LAMOTRIGINE | NEUROVASCULAR COMPRESSION | CARBAMAZEPINE | EVOKED-POTENTIALS | CLINICAL NEUROLOGY
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10. Full Text Lesson of the month 1: To stop a fi t, but swinging low
by Ogbebor, Osakpolor and Agrawal, Ankit and Yegneswaran, Balaji
Clinical Medicine, Journal of the Royal College of Physicians of London, ISSN 1470-2118, 06/2018, Volume 18, Issue 3, pp. 256 - 258
Oxcarbazepine | Side Effect | Thrombocytopenia | Antiepileptic Drugs | Carbamazepine
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11. Full Text Development of a practical, biocatalytic reduction for the manufacture of (s)-licarbazepine using an evolved ketoreductase
by Modukuru, Naga K and Sukumaran, Joly and Collier, Steven J and Chan, Ann Shu and Gohel, Anupam and Huisman, Gjalt W and Keledjian, Raquel and Narayanaswamy, Karthik and Novick, Scott J and Palanivel, S.M and Smith, Derek and Wei, Zhang and Wong, Brian and Yeo, Wan Lin and Entwistle, David A
Organic Process Research and Development, ISSN 1083-6160, 06/2014, Volume 18, Issue 6, pp. 810 - 815
This contribution describes the development of a ketoreductase enzyme over four rounds of directed evolution and the associated process development that... 
CHEMISTRY, ORGANIC | OXCARBAZEPINE | EPILEPSY | CHEMISTRY, APPLIED
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12. Full Text Demyelinating peripheral polyradiculoneuropathy associated with the use of carbamazepine in dog: case report
by Caramalac, SM and Fernandes, TD and Palumbo, MIP
ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA, ISSN 0102-0935, 11/2018, Volume 70, Issue 6, pp. 1754 - 1758
Different drugs are used in the treatment of epilepsy and, like other drugs, may induce the occurrence of adverse effects, some of them so severe that the drug... 
epilepsy | OXCARBAZEPINE | electroneuromyography | drugs | VETERINARY SCIENCES | polyradiculoneuropathy
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13. Full Text The unmasking of hidden severe hyponatremia after long-term combination therapy in exacerbated bipolar patients: a case series
by Fabrazzo, Michele and Fuschillo, Antonietta and Perris, Francesco and Catapano, Francesco
International Clinical Psychopharmacology, ISSN 0268-1315, 07/2019, Volume 34, Issue 4, pp. 206 - 210
Hyponatremia is occasionally unmasked in psychiatric patients during hospitalization after routine blood and urinary tests, and correlates in most cases with... 
syndrome of inappropriate antidiuretic hormone secretion | OXCARBAZEPINE-INDUCED HYPONATREMIA | DEPRESSION | MANAGEMENT | PSYCHIATRY | polypharmacotherapy | CARBAMAZEPINE | RISK | INAPPROPRIATE SECRETION | bipolar disorder | ANTIDEPRESSANTS | oxcarbazepine | ANTIPSYCHOTICS | hyponatremia | PHARMACOLOGY & PHARMACY | MOOD STABILIZERS | Medicine, Experimental | Medical research | Hyponatremia | Risk factors
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14. Full Text Estudio postautorización de la eslicarbazepina en el tratamiento de epilepsias farmacorresistentes: Resultados preliminares
by Massot, A and Vivanco, R and Principe, A and Roquer, J and Rocamora, R
Neurologia, ISSN 0213-4853, 03/2014, Volume 29, Issue 2, pp. 94 - 101
Introduction: Eslicarbazepine acetate (ESL) is a new antiepileptic drug (AED) and an analogue to carbamazepine (CBZ) and oxcarbazepine (OXC). In this study, we... 
Oxcarbazepine | Eslicarbazepine | Drug-resistant | Epilepsy | Carbamazepine
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15. Adverse effects of oxcarbazepine
by Fang, Shu and Gong, Zhi-Cheng
Chinese Journal of Contemporary Pediatrics, ISSN 1008-8830, 04/2015, Volume 17, Issue 4, pp. 414 - 419
Oxcarbazepine | Epilepsy | Adverse effect
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16. Full Text The potential impacts of the anti-epileptic drug (Oxcarbazepine) on albino rat’s neonates during lactation
by Hamdi, Hamida and El Ghareeb, Abd El Wahab and Kandil, Asmaa M and Ahmed, Osama M and Yahia, Rania
Asian Journal of Pharmaceutical and Clinical Research, ISSN 0974-2441, 08/2016, Volume 9, pp. 244 - 251
Antiepileptic drug | Oxcarbazepine | Rats | Lactation
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17. Association between HLA-B∗15:02 and oxcarbazepine-induced cutaneous adverse reaction: A meta-analysis
by Liu, Yiwei and Yu, Yuncui and Nie, Xiaolu and Zhao, Libo and Wang, Xiaoling
Pharmacogenomics, ISSN 1462-2416, 04/2018, Volume 19, Issue 6, pp. 547 - 552
15:02 | oxcarbazepine | HLA-B | cutaneous adverse reaction
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18. Full Text Oxcarbazepine versus phenytoin monotherapy for epilepsy: An individual participant data review
by Nevitt, Sarah J and Tudur Smith, Catrin and Marson, Anthony G
Cochrane Database of Systematic Reviews, ISSN 1469-493X, 10/2018, Volume 2018, Issue 10, p. CD003615
Background This is an updated version of the Cochrane Review previously published in 2013. This review is one in a series of Cochrane Reviews investigating... 
Epilepsy [drug therapy] | Carbamazepine [analogs & derivatives | Anticonvulsants [therapeutic use] | EFFICACY | Phenytoin [therapeutic use] | Humans | UNPROVOKED SEIZURES | Epilepsies, Partial [drug therapy] | Induction Chemotherapy | CARBAMAZEPINE | CLASSIFICATION | DATA METAANALYSIS | Randomized Controlled Trials as Topic | PREGNANCY | MEDICINE, GENERAL & INTERNAL | SODIUM VALPROATE | CLINICAL-TRIALS | DOUBLE-BLIND | ANTIEPILEPTIC DRUGS | therapeutic use | Epilepsy, Tonic-Clonic - drug therapy | Oxcarbazepine - therapeutic use | Epilepsies, Partial - drug therapy | Proportional Hazards Models | Anticonvulsants - therapeutic use | Oxcarbazepine - adverse effects | Anticonvulsants - adverse effects | Phenytoin - therapeutic use | Phenytoin - adverse effects | Treatment Failure
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19. Full Text The Novel Activity of Carbamazepine as an Activation Modulator Extends from Na(v)1.7 Mutations to the Na(v)1.8-S242T Mutant Channel from a Patient with Painful Diabetic Neuropathy
by Han, CY and Themistocleous, AC and Estacion, M and Dib-Hajj, FB and Blesneac, I and Macala, L and Fratter, C and Bennett, DL and Waxman, SG and Dib-Hajj, SD
MOLECULAR PHARMACOLOGY, ISSN 0026-895X, 11/2018, Volume 94, Issue 5, pp. 1256 - 1269
Neuropathic pain in patients carrying sodium channel gain-of-function mutations is generally refractory to pharmacotherapy. However, we have shown that... 
ACTION-POTENTIALS | OXCARBAZEPINE | DIAGNOSIS | PHENYTOIN | ROOT GANGLION NEURONS | SODIUM-CHANNELS | LIDOCAINE | PHENOTYPE | PHARMACOLOGY & PHARMACY | BINDING
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20. Full Text Rapid and safe response to low‐dose carbamazepine in neonatal epilepsy
by Sands, Tristan T and Balestri, Martina and Bellini, Giulia and Mulkey, Sarah B and Danhaive, Olivier and Bakken, Eliza Hayes and Taglialatela, Maurizio and Oldham, Michael S and Vigevano, Federico and Holmes, Gregory L and Cilio, Maria Roberta
Epilepsia, ISSN 0013-9580, 12/2016, Volume 57, Issue 12, pp. 2019 - 2030
ObjectiveTo evaluate treatment responses in benign familial neonatal epilepsy (BFNE). MethodsWe recruited patients with BFNE through a multicenter... 
Oxcarbazepine | KCNQ | Neonatal seizures | Benign familial neonatal epilepsy | Carbamazepine | KCNQ3 | KCNQ2 | EEG | CLINICAL NEUROLOGY | CHILDREN | CENTROTEMPORAL SPIKES | SEIZURES | FAMILIES | INFANTILE CONVULSIONS | CHANNELS | MUTATIONS | KCNQ2 ENCEPHALOPATHY | DELETIONS | Carbamazepine - pharmacology | Follow-Up Studies | Humans | NAV1.2 Voltage-Gated Sodium Channel - genetics | Anticonvulsants - therapeutic use | Child, Preschool | Family Health | Infant | Male | Electroencephalography | Mutation - genetics | Gestational Age | Potassium Channels - genetics | Magnetic Resonance Imaging | Epilepsy, Benign Neonatal - drug therapy | Epilepsy, Benign Neonatal - genetics | Female | Epilepsy, Benign Neonatal - diagnostic imaging | Infants (Newborn) | Dosage and administration | Seizures (Medicine) | Epilepsy
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