X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (3442) 3442
Publication (334) 334
Book Review (20) 20
Book Chapter (19) 19
Conference Proceeding (5) 5
Book / eBook (3) 3
Paper (2) 2
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (1657) 1657
humans (1642) 1642
index medicus (1309) 1309
oximes - pharmacology (1155) 1155
male (1136) 1136
oximes (923) 923
female (723) 723
rats (685) 685
biochemistry & molecular biology (557) 557
oximes - chemistry (556) 556
mice (503) 503
pharmacology & pharmacy (487) 487
acetylcholinesterase - metabolism (434) 434
oximes - metabolism (419) 419
adult (394) 394
toxicology (376) 376
middle aged (367) 367
technetium tc 99m exametazime (364) 364
acetylcholinesterase (327) 327
kinetics (301) 301
structure-activity relationship (295) 295
tomography, emission-computed, single-photon (278) 278
chemistry, medicinal (275) 275
oxime (274) 274
oximes - therapeutic use (264) 264
oximes - pharmacokinetics (256) 256
organotechnetium compounds (255) 255
cholinesterase reactivators - pharmacology (253) 253
analysis (252) 252
aged (243) 243
in vitro techniques (241) 241
dose-response relationship, drug (236) 236
neurosciences (234) 234
brain - metabolism (216) 216
molecular structure (216) 216
indoles - pharmacology (211) 211
brain - diagnostic imaging (206) 206
pyridinium compounds - pharmacology (198) 198
oximes - chemical synthesis (196) 196
enzymes (188) 188
time factors (183) 183
metabolism (176) 176
inhibition (174) 174
brain (173) 173
cell line, tumor (171) 171
rats, wistar (170) 170
article (167) 167
cholinesterase inhibitors - pharmacology (166) 166
chemistry, organic (163) 163
radiology, nuclear medicine & medical imaging (158) 158
soman (154) 154
reactivation (153) 153
organophosphorus compounds (151) 151
in-vitro (147) 147
oximes - administration & dosage (147) 147
chemistry, multidisciplinary (139) 139
rats, sprague-dawley (139) 139
cells, cultured (138) 138
research (138) 138
cerebrovascular circulation (134) 134
endocrinology & metabolism (133) 133
expression (132) 132
spect (132) 132
phosphorylation (131) 131
radionuclide imaging (128) 128
activation (125) 125
models, molecular (125) 125
oncology (125) 125
brain - drug effects (122) 122
hi-6 (121) 121
ligands (121) 121
cholinesterase inhibitors - toxicity (116) 116
physiological aspects (116) 116
brain - enzymology (115) 115
enzyme inhibitors - pharmacology (115) 115
organotechnetium compounds - pharmacokinetics (115) 115
cancer (114) 114
nerve agents (112) 112
proteins (112) 112
cell biology (111) 111
tabun (111) 111
derivatives (110) 110
binding sites (107) 107
clinical neurology (107) 107
protein binding (107) 107
cell line (104) 104
mutation (103) 103
cholinesterase reactivators - chemistry (101) 101
rabbits (100) 100
apoptosis (98) 98
poisoning (98) 98
antineoplastic agents - pharmacology (97) 97
cell proliferation - drug effects (97) 97
efficacy (96) 96
binding (95) 95
chemistry (94) 94
tissue distribution (94) 94
guinea pigs (93) 93
mass spectrometry (93) 93
inhibitors (92) 92
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (3354) 3354
Japanese (20) 20
German (18) 18
Russian (18) 18
Czech (10) 10
French (8) 8
Chinese (7) 7
Spanish (4) 4
Croatian (3) 3
Italian (3) 3
Polish (3) 3
Serbian (2) 2
Bulgarian (1) 1
Dutch (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Neuroscience, ISSN 0270-6474, 03/2013, Volume 33, Issue 13, pp. 5603 - 5611
Visceral afferents expressing transient receptor potential (TRP) channels TRPV1 and TRPA1 are thought to be required for neurogenic inflammation and... 
ACTIVATION | SUBPOPULATIONS | PHOSPHORYLATION | SENSITIZATION | PROTEIN-KINASE | HYPERALGESIA | EXPRESSION | NEUROSCIENCES | SENSORY NEURONS | ERK | Calcium - metabolism | Male | Nodose Ganglion - metabolism | RNA, Messenger - metabolism | Amidines - metabolism | Time Factors | TRPV Cation Channels - antagonists & inhibitors | Pancreatitis, Chronic - drug therapy | Exploratory Behavior - drug effects | Monocytes - pathology | Pain - etiology | Sensory Receptor Cells - metabolism | Transient Receptor Potential Channels - metabolism | Calcitonin Gene-Related Peptide - metabolism | Neutrophil Infiltration - drug effects | Disease Models, Animal | Injections, Intraperitoneal | Pancreas - pathology | Analgesics, Opioid - therapeutic use | Pancreas - metabolism | Pain - pathology | Disease Progression | Pancreatitis, Chronic - pathology | Analysis of Variance | Transient Receptor Potential Channels - genetics | Ganglia, Spinal - pathology | Mice | Transient Receptor Potential Channels - antagonists & inhibitors | Oximes - therapeutic use | Pancreatitis, Chronic - chemically induced | Monocytes - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | TRPV Cation Channels - metabolism | Antigens, Differentiation - metabolism | Pyridines - therapeutic use | Sensory Receptor Cells - pathology | Pain - prevention & control | Mice, Inbred C57BL | Ceruletide - toxicity | Pancreas - drug effects | Pain Measurement - drug effects | TRPV Cation Channels - genetics | Gene Expression Regulation - drug effects | Nodose Ganglion - pathology | Animals | Sensory Receptor Cells - drug effects | Pancreatitis, Chronic - complications | TRPA1 Cation Channel | Morphine - therapeutic use | Ganglia, Spinal - metabolism | Peroxidase - metabolism
Journal Article
Plant Cell, ISSN 1040-4651, 5/2015, Volume 27, Issue 5, pp. 1529 - 1546
Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2010, Volume 12, Issue 9, pp. 876 - 885
Keratins 8 and 18 (K8 and K18) are heteropolymeric intermediate filament phosphoglycoproteins of simple-type epithelia. Mutations in K8 and K18 predispose the... 
CELLS | SIGNALING PATHWAYS | MITOTIC ARREST | KINASE-B | O-GLCNAC MODIFICATION | LIVER-DISEASE | NUCLEOCYTOPLASMIC PROTEINS | LINKED N-ACETYLGLUCOSAMINE | INTERMEDIATE-FILAMENTS | TRANSGENIC MICE | CELL BIOLOGY | Liver - pathology | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Apoptosis - genetics | Glycosylation - drug effects | Pancreas - injuries | Phosphorylation - genetics | Keratins - metabolism | Liver - drug effects | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Antibodies, Monoclonal - immunology | Protein-Serine-Threonine Kinases - metabolism | Chemical and Drug Induced Liver Injury - prevention & control | Antibodies, Monoclonal - pharmacology | Liver - metabolism | Enzyme Inhibitors - pharmacology | Pancreas - pathology | Acetylglucosamine - pharmacology | Mice, Transgenic | Pancreas - metabolism | Mice, Knockout | Phenylcarbamates - pharmacology | fas Receptor - agonists | Chemical and Drug Induced Liver Injury - metabolism | Models, Biological | Cytoskeleton - metabolism | Cytosol - metabolism | Mice | Keratins - genetics | Protein Binding - physiology | Cytosol - drug effects | Hepatocytes - metabolism | Proto-Oncogene Proteins c-akt - genetics | fas Receptor - immunology | Acetylglucosamine - analogs & derivatives | Chemical and Drug Induced Liver Injury - pathology | Hepatocytes - drug effects | Keratins - chemistry | Pancreas - drug effects | beta-N-Acetylhexosaminidases - antagonists & inhibitors | Chemical and Drug Induced Liver Injury - genetics | Glycogen Synthase Kinase 3 - metabolism | Mice, Inbred Strains | Streptozocin - pharmacology | Keratin-18 - genetics | HSP70 Heat-Shock Proteins - metabolism | Protein Kinase C-delta - metabolism | Animals | Keratin-8 - metabolism | Keratin-18 - metabolism | Oximes - pharmacology | Amino Acid Substitution - genetics | Keratin | Liver diseases | Gene mutations | Physiological aspects | Glycosylation | Genetic aspects | Research | Health aspects | Risk factors
Journal Article
Cell and Tissue Research, ISSN 0302-766X, 10/2012, Volume 350, Issue 1, pp. 95 - 107
Epiprofin/Specificity Protein 6 (Epfn) is a Krüppel-like family (KLF) transcription factor that is critically involved in tooth morphogenesis and dental cell... 
Human Genetics | Mouse Epfn (+/−) | Biomedicine | Tooth development | Epiprofin/Sp6 | Wnt/β-catenin | Proteomics | Cell junction | Molecular Medicine | MDPC-23 | Epfn (−/−) | Mouse Epfn(+/-); Epfn(-/-) | TEETH | PROLIFERATION | BETA-CATENIN | CELL BIOLOGY | MORPHOGENESIS | EPITHELIUM | DENTIN | Wnt/beta-catenin | GROWTH | TRANSCRIPTION FACTOR | EXPRESSION | MOUSE INCISORS | Dental Pulp - embryology | Dental Pulp - metabolism | Wnt Proteins - metabolism | Incisor - cytology | Bone Morphogenetic Proteins - metabolism | Incisor - metabolism | Tooth - embryology | Tight Junctions - drug effects | Biomarkers - metabolism | Tight Junctions - metabolism | Dental Enamel - metabolism | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Dental Pulp - cytology | Dental Pulp - drug effects | Dental Papilla - embryology | beta Catenin - metabolism | Molar - embryology | Signal Transduction - drug effects | Adherens Junctions - drug effects | Mice | Dental Enamel - cytology | Dental Papilla - drug effects | Adherens Junctions - metabolism | Ameloblasts - metabolism | Kruppel-Like Transcription Factors - metabolism | Molar - cytology | Ameloblasts - drug effects | Tooth - cytology | Membrane Proteins - metabolism | Molar - drug effects | Kruppel-Like Transcription Factors - deficiency | Molar - metabolism | Odontoblasts - cytology | Recombinant Proteins - metabolism | Odontoblasts - metabolism | Incisor - drug effects | Ameloblasts - cytology | Intercellular Junctions - metabolism | Dental Papilla - metabolism | Glycogen Synthase Kinase 3 - metabolism | Dental Enamel - embryology | Dental Papilla - cytology | Animals | Intercellular Junctions - drug effects | Odontoblasts - drug effects | Morphogenesis - drug effects | Oximes - pharmacology | Cell Proliferation - drug effects | Incisor - embryology | Tooth - metabolism | Dental Enamel - drug effects | Developmental biology | Rodents | Teeth | Cell proliferation | Bone morphogenetic protein 4 | Nestin | Transcription factors | Mesenchyme | Tight junctions | Wnt protein | catenin | Cell junctions | Morphogenesis | Signal transduction | Dental enamel | Ameloblasts | Developmental stages | Incisors | Bone morphogenetic proteins | Differentiation | Dental pulp
Journal Article
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 2014, Volume 10, Issue 8, pp. 671 - 676
(+)-7-iso-Jasmonoyl-L-isoleucine (JA-Ile) regulates developmental and stress responses in plants. Its perception involves the formation of a ternary complex... 
SIGNAL-TRANSDUCTION | PLANT STRESS-RESPONSE | DOMAIN PROTEINS INTERACT | PATHOGEN | AUXIN PERCEPTION | BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | JAZ REPRESSORS | ARABIDOPSIS | BHLH TRANSCRIPTION FACTORS | REGULATED DEFENSE | Indenes - metabolism | Amino Acids - chemistry | Indenes - chemistry | Amino Acids - pharmacology | Pseudomonas syringae - pathogenicity | Arabidopsis Proteins - metabolism | Botrytis - pathogenicity | DNA-Binding Proteins - metabolism | Amino Acids - metabolism | Isoleucine - pharmacology | Plants, Genetically Modified | Drug Design | Gene Expression Regulation, Plant | Plant Roots - growth & development | Repressor Proteins - metabolism | Amino Acids, Neutral - pharmacology | Indenes - pharmacology | Arabidopsis Proteins - genetics | Arabidopsis - drug effects | DNA-Binding Proteins - antagonists & inhibitors | Plant Roots - metabolism | Repressor Proteins - genetics | Transcription Factors - antagonists & inhibitors | Cyclopentanes - pharmacology | Anthocyanins - metabolism | Arabidopsis - metabolism | Isoleucine - metabolism | Transcription Factors - metabolism | Arabidopsis - microbiology | Oxylipins - metabolism | Isoleucine - analogs & derivatives | Oximes - pharmacology | Cyclopentanes - metabolism | Ligands | Arabidopsis Proteins - antagonists & inhibitors | Plant diseases | Plant pathology | Sustainable agriculture | Agricultural biotechnology | Plant resistance | Hormones
Journal Article
Structure, ISSN 0969-2126, 04/2018, Volume 26, Issue 4, pp. 533 - 544.e3
Small conductance potassium (SK) ion channels define neuronal firing rates by conducting the after-hyperpolarization current. They are key targets in... 
KCa | CyPPA | SK2 | structure-based drug discovery | ion channels | riluzole | RILUZOLE | ATAXIA TYPE-2 | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CA2+-ACTIVATED K+ CHANNELS | ACTIVATED POTASSIUM CHANNELS | CELL BIOLOGY | BIOPHYSICS | SPIKE FREQUENCY ADAPTATION | CALMODULIN | NEURONS | DRUGGABILITY | SMALL-CONDUCTANCE | Calmodulin - genetics | Small-Conductance Calcium-Activated Potassium Channels - genetics | Allosteric Regulation | Humans | Crystallography, X-Ray | Pyrimidines - chemistry | Pyrimidines - metabolism | Indoles - metabolism | Pyrazoles - chemistry | Oximes - metabolism | Cloning, Molecular | Escherichia coli - metabolism | HEK293 Cells | Protein Interaction Domains and Motifs | Calmodulin - chemistry | Binding Sites | Recombinant Proteins - metabolism | Protein Conformation, alpha-Helical | Gene Expression | Calmodulin - metabolism | Genetic Vectors - chemistry | Anticonvulsants - metabolism | Genetic Vectors - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Pyrazoles - metabolism | Small-Conductance Calcium-Activated Potassium Channels - chemistry | Small-Conductance Calcium-Activated Potassium Channels - metabolism | Amino Acid Motifs | Oximes - chemistry | Escherichia coli - genetics | Riluzole - chemistry | Anticonvulsants - chemistry | Protein Binding | Riluzole - metabolism | Indoles - chemistry | Neurosciences | Amines | Neurons | Epilepsy | Ion channels | Drug discovery | Calcium-binding proteins | Calmodulin
Journal Article
The Plant Journal, ISSN 0960-7412, 11/2015, Volume 84, Issue 3, pp. 558 - 573
Journal Article
The Plant Cell, ISSN 1040-4651, 11/2013, Volume 25, Issue 11, pp. 4737 - 4754
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2002, Volume 99, Issue 8, pp. 5313 - 5318
Increased flux of glucose through the hexosamine biosynthetic pathway (HSP) is believed to mediate hyperglycemia-induced insulin resistance in diabetes. The... 
Biological Sciences | Receptors | Phosphorylation | 3T3 L1 cells | Antibodies | Insulin resistance | Adipocytes | Physiological regulation | Diabetes | Insulin | Western blotting | SKELETAL-MUSCLE | NUCLEAR | TETRATRICOPEPTIDE REPEATS | CYTOPLASMIC PROTEINS | MULTIDISCIPLINARY SCIENCES | GLYCOGEN-SYNTHASE KINASE-3 | PROTEINS IN-VIVO | CYTOSOLIC PROTEINS | GLUCOSE TOXICITY | BETA-CATENIN | LINKED N-ACETYLGLUCOSAMINE | Phenylcarbamates | Protein-Serine-Threonine Kinases | Cytoplasm - metabolism | Glycogen Synthase Kinase 3 | Phosphoproteins - metabolism | Glucosamine - metabolism | Acetylglucosamine - metabolism | Dose-Response Relationship, Drug | Glycogen Synthase Kinases | Cell Nucleus - metabolism | Time Factors | Oximes - metabolism | Insulin Receptor Substrate Proteins | Acetylglucosamine - analogs & derivatives | Cytoskeletal Proteins - metabolism | Catalysis | Proto-Oncogene Proteins - metabolism | Cell Line | Insulin - pharmacology | Signal Transduction | beta Catenin | Trans-Activators | Insulin Resistance | Glycosylation | Blotting, Western | Precipitin Tests | Proto-Oncogene Proteins c-akt | Insulin - metabolism | Tyrosine - metabolism | Animals | Adipocytes - metabolism | Glucose - pharmacokinetics | Protein Binding | Mice | Protein Processing, Post-Translational | Enzyme Activation | 3T3 Cells | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Hexosamines | Physiological aspects | Fat cells | Research
Journal Article
Journal Article
</