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1. Full Text The selective condensation of pyrazolones to isatins in aqueous medium
by Zhang, Yong and Nie, Long-Jun and Luo, Liang and Mao, Jia-Xin and Liu, Jin-Xiang and Xu, Guo-Hai and Chen, Deliang and Luo, Hai-Qing
Tetrahedron, ISSN 0040-4020, 02/2020, Volume 76, Issue 7, p. 130916
Water | Oxindoles | Condensation | Pyrazolones
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2. Full Text Chiral iminophosphorane catalyzed asymmetric phenylselenylation of 3-substituted oxindoles
by Zhang, Yanxia and Wu, Xin-Yan and Han, Jianwei and Wong, Henry N.C
Tetrahedron letters, ISSN 0040-4039, 03/2020, Volume 61, Issue 10, p. 151559
Phenylselenylation | Organocatalysis iminophosphorane | Oxindoles
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3. Full Text Regioselective Friedel–Crafts Reaction of Electron‐Rich Benzenoid Arenes and Spiroepoxyoxindole at the Spiro‐Centre: Efficient Synthesis of Benzofuroindolines and 2H‐ Spiro[benzofuran]‐3,3′‐oxindoles
by Hajra, Saumen and Maity, Subrata and Roy, Sayan
Advanced synthesis & catalysis, ISSN 1615-4150, 07/2016, Volume 358, Issue 14, pp. 2300 - 2306
Friedel–Crafts reaction | benzofuroindolines | spiroepoxyoxindoles | benzenoid arenes | spiro[benzofuran]‐3,3′‐oxindoles | 3‐aryl‐3‐(hydroxymethyl)oxindoles | 3-aryl-3-(hydroxymethyl)oxindoles | spiro[benzofuran]-3,3′-oxindoles | Synthesis (chemistry) | Synthesis | Aromatic compounds | Benzenoids | Phenols | Catalysis | Ring opening | Friedel-Crafts reaction
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4. Full Text Thiourea-catalyzed asymmetric domino Michael-cyclization reaction of 3-isothiocyanato oxindoles with β,γ-unsaturated α-keto esters for the synthesis of spirocyclic oxindoles
by Bai, Mei and Chen, Yong-Zheng and Cui, Bao-Dong and Xu, Xiao-Ying and Yuan, Wei-Cheng
Tetrahedron, ISSN 0040-4020, 04/2019, Volume 75, Issue 14, pp. 2155 - 2161
3-Isothiocyanato oxindoles | Spirocyclic oxindoles | β,γ-unsaturated α-keto esters
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5. Full Text Recent Advances in Asymmetric Organocatalytic Construction of 3,3′‐Spirocyclic Oxindoles
by Hong, Liang and Wang, Rui
Advanced synthesis & catalysis, ISSN 1615-4150, 04/2013, Volume 355, Issue 6, pp. 1023 - 1052
organocatalysis | spiro‐oxindoles | asymmetric catalysis | stereoselectivity | spiro-oxindoles | Physical Sciences | Chemistry | Chemistry, Organic | Chemistry, Applied | Science & Technology | Strategy | Construction | Synthesis | Catalysis | Asymmetry | Construction equipment
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6. Full Text Design, synthesis and in vitro study of densely functionalized oxindoles as potent α-glucosidase inhibitors
by Luthra, Tania and Naga Lalitha, K and Agarwal, Rahul and Uma, A and Sen, Subhabrata
Bioorganic & medicinal chemistry, ISSN 0968-0896, 10/2018, Volume 26, Issue 18, pp. 4996 - 5005
Oxindoles - pharmacology | Oxindoles - therapeutic use | Humans | Glycoside Hydrolase Inhibitors - therapeutic use | Structure-Activity Relationship | Yeasts - enzymology | Glycoside Hydrolase Inhibitors - chemistry | Glycoside Hydrolase Inhibitors - pharmacology | Glycoside Hydrolase Inhibitors - chemical synthesis | Oxindoles - chemistry | Drug Design | Inhibitory Concentration 50 | Molecular Docking Simulation | Kinetics | Diabetes Mellitus, Type 2 - drug therapy | Oxindoles - chemical synthesis | alpha-Glucosidases - metabolism | Index Medicus
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7. Full Text Oxindole based oxadiazole hybrid analogs: Novel α-glucosidase inhibitors
by Taha, Muhammad and Imran, Syahrul and Rahim, Fazal and Wadood, Abdul and Khan, Khalid Mohammed
Bioorganic chemistry, ISSN 0045-2068, 02/2018, Volume 76, pp. 273 - 280
Oxindole | Molecular docking study | Oxadiazole | α-glucosidase | Synthesis | SAR | Catalytic Domain | Oxadiazoles - chemical synthesis | Glycoside Hydrolase Inhibitors - metabolism | Oxindoles - metabolism | Enzyme Assays | Structure-Activity Relationship | Glycoside Hydrolase Inhibitors - chemistry | Glycoside Hydrolase Inhibitors - chemical synthesis | Oxindoles - chemistry | Hydrogen Bonding | Protein Binding | Molecular Docking Simulation | Molecular Structure | Oxadiazoles - chemistry | Oxindoles - chemical synthesis | alpha-Glucosidases - metabolism | Oxadiazoles - metabolism | alpha-Glucosidases - chemistry | Index Medicus
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8. Full Text Dual inhibition of Kif15 by oxindole and quinazolinedione chemical probes
by Dumas, Megan E and Chen, Geng-Yuan and Kendrick, Nicole D and Xu, George and Larsen, Scott D and Jana, Somnath and Waterson, Alex G and Bauer, Joshua A and Hancock, William and Sulikowski, Gary A and Ohi, Ryoma
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 01/2019, Volume 29, Issue 2, pp. 148 - 154
Oxindole | Eg5 | Mitosis | Kinesin | Kif15 | Oxindoles - pharmacology | Humans | Enzyme Inhibitors - pharmacology | Molecular Probes - pharmacology | Structure-Activity Relationship | Molecular Probes - chemical synthesis | Enzyme Inhibitors - chemical synthesis | Kinesin - metabolism | Dose-Response Relationship, Drug | Quinazolinones - chemical synthesis | Oxindoles - chemistry | Molecular Probes - chemistry | Enzyme Inhibitors - chemistry | Molecular Structure | Quinazolinones - chemistry | Oxindoles - chemical synthesis | Kinesin - antagonists & inhibitors | Quinazolinones - pharmacology | Index Medicus | oxindole | mitosis | kinesin
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9. Full Text Discovery of 3,3′-pyrrolidinyl-spirooxindoles as cardioprotectant prohibitin ligands
by Elderwish, Sabria and Audebrand, Anaïs and Nebigil, Canan G and Désaubry, Laurent
European journal of medicinal chemistry, ISSN 0223-5234, 01/2020, Volume 186, pp. 111859 - 111859
Oxindoles | Cardiotoxicity | Doxorubicin | Prohibitins | STAT3 | Oxindoles - pharmacology | Cell Line | Cell Survival - drug effects | Apoptosis - drug effects | Doxorubicin - antagonists & inhibitors | Humans | Cardiotonic Agents - chemistry | Structure-Activity Relationship | Cardiotonic Agents - pharmacology | Drug Discovery | Repressor Proteins - antagonists & inhibitors | Dose-Response Relationship, Drug | Oxindoles - chemistry | Myocytes, Cardiac - drug effects | Cardiotonic Agents - chemical synthesis | Spiro Compounds - chemical synthesis | Myocytes, Cardiac - metabolism | Ligands | Molecular Structure | Oxindoles - chemical synthesis | Doxorubicin - pharmacology | Repressor Proteins - metabolism | Spiro Compounds - chemistry | Spiro Compounds - pharmacology | Index Medicus | Life Sciences | Human health and pathology | Cardiology and cardiovascular system
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10. Full Text Bulky Chiral Carbene Ligands and Their Application in the Palladium‐Catalyzed Asymmetric Intramolecular α‐Arylation of Amides
by Kündig, E. Peter and Seidel, Thomas M and Jia, Yi‐xia and Bernardinelli, Gérald
Angewandte Chemie (International ed.), ISSN 1433-7851, 11/2007, Volume 46, Issue 44, pp. 8484 - 8487
oxindoles | palladium | asymmetric catalysis | NHC ligands | heterocycles | Heterocycles | Oxindoles | Palladium | Asymmetric catalysis
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11. Full Text Highly efficient construction of chiral dispirocyclic oxindole/thiobutyrolactam/chromanone complexes through Michael/cyclization cascade reactions with a rosin-based squaramide catalyst
by Lin, Ning and Long, Xian-wen and Chen, Qing and Zhu, Wen-run and Wang, Bi-chuan and Chen, Kai-bin and Jiang, Cai-wu and Weng, Jiang and Lu, Gui
Tetrahedron, ISSN 0040-4020, 07/2018, Volume 74, Issue 27, pp. 3734 - 3741
Chromanones | Rosin-based squaramide catalyst | Dispirocyclic oxindoles | 3-Isothiocyanato oxindoles | Asymmetric organocatalysis | Drugstores | Pharmacy | Catalysis
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12. Full Text Palladium-Catalyzed, Enantioselective α‑Arylation of α‑Fluorooxindoles
by Jin, Yushu and Chen, Ming and Ge, Shaozhong and Hartwig, John F
Organic letters, ISSN 1523-7060, 03/2017, Volume 19, Issue 6, pp. 1390 - 1393
Oxidation-Reduction | Stereoisomerism | Molecular Structure | Catalysis | Mesylates - chemistry | Oxindoles - chemical synthesis | Palladium - chemistry | Index Medicus
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13. Full Text Catalytic asymmetric synthesis of 3,3-disubstituted oxindoles: diazooxindole joins the field
by Cao, Zhong-Yan and Wang, Yu-Hui and Zeng, Xing-Ping and Zhou, Jian
Tetrahedron letters, ISSN 0040-4039, 04/2014, Volume 55, Issue 16, pp. 2571 - 2584
Diazooxindole | Asymmetric catalysis | Spirocyclic oxindoles | Privileged scaffold | 3,3-Disubstituted oxindoles | Physical Sciences | Chemistry | Chemistry, Organic | Science & Technology | Synthesis | Organic compounds | Synthesis (chemistry) | Asymmetry | Catalysts | Tetrahedrons | Strategy | Catalysis | Scaffolds | Readers
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14. Full Text Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors
by Lozinskaya, Natalia A and Babkov, Denis A and Zaryanova, Ekaterina V and Bezsonova, Elena N and Efremov, Alexander M and Tsymlyakov, Michael D and Anikina, Lada V and Zakharyascheva, Olga Yu and Borisov, Alexander V and Perfilova, Valentina N and Tyurenkov, Ivan N and Proskurnina, Marina V and Spasov, Alexander A
Bioorganic & medicinal chemistry, ISSN 0968-0896, 05/2019, Volume 27, Issue 9, pp. 1804 - 1817
GSK3β | Antidiabetic | Indolin-2-one | 3-Substituted indolinone | Glycogen synthase kinase 3 | Oxindole derivatives | Anticancer | Oxindoles - pharmacology | A549 Cells | Cell Survival - drug effects | Protein Kinase Inhibitors - chemical synthesis | Catalytic Domain | Diabetes Mellitus, Experimental - drug therapy | Glucose Tolerance Test | Oxindoles - therapeutic use | Humans | Rats | Glycogen Synthase Kinase 3 beta - antagonists & inhibitors | Structure-Activity Relationship | Glycogen Synthase Kinase 3 beta - metabolism | Oxindoles - chemistry | Animals | Protein Kinase Inhibitors - therapeutic use | Inhibitory Concentration 50 | Diabetes Mellitus, Experimental - chemically induced | Molecular Docking Simulation | Protein Kinase Inhibitors - pharmacology | Binding Sites | Index Medicus
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