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Neuropsychopharmacology, ISSN 0893-133X, 2002, Volume 26, Issue 3, pp. 325 - 339
The role of acetylcholine (ACh) in the action of antipsychotic drugs (APDs) was studied by microdialysis, without AChesterase inhibition, to facilitate the... 
Nucleus accumbens | Schizophrenia | Medial prefrontal cortex | Striatum | Typical and atypical antipsychotic drugs | Acetylcholine release | FREELY MOVING RATS | IN-VIVO MICRODIALYSIS | medial prefrontal cortex | PSYCHIATRY | acetylcholine release | ENDOGENOUS SEROTONIN | nucleus accumbens | schizophrenia | typical and atypical antipsychotic drugs | MUSCARINIC RECEPTOR AGONIST | NEUROSCIENCES | PREFRONTAL CORTEX | BRAIN MICRODIALYSIS | striatum | EXTRACELLULAR ACETYLCHOLINE | RAT FRONTAL-CORTEX | INDUCED DOPAMINE RELEASE | PHARMACOLOGY & PHARMACY | 5-HT1B RECEPTORS | Acetylcholine - biosynthesis | Oxotremorine - pharmacology | Sulpiride - pharmacology | Nucleus Accumbens - metabolism | Male | Corpus Striatum - metabolism | Cerebral Cortex - metabolism | Scopolamine Hydrobromide - pharmacology | Clozapine - pharmacology | Cerebral Cortex - drug effects | Pirenzepine - pharmacology | Haloperidol - pharmacology | Pirenzepine - analogs & derivatives | Risperidone - pharmacology | Rats | Piperazines - pharmacology | Rats, Sprague-Dawley | Acetylcholine - secretion | Benzodiazepines | Animals | Cholinesterase Inhibitors - pharmacology | Thioridazine - pharmacology | Corpus Striatum - drug effects | Antipsychotic Agents - metabolism | Thiazoles - pharmacology | Antipsychotic Agents - pharmacology | Nucleus Accumbens - drug effects | Acetylcholinesterase - metabolism
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 07/2015, Volume 42, Issue 2, pp. 1797 - 1807
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 01/2009, Volume 156, Issue 1, pp. 173 - 180
Background and purpose:  Galantamine, a weak acetylcholine esterase (AChE) inhibitor and allosteric potentiator of nicotinic ACh receptors (nAChRs), improves... 
ACh release | apomorphine | muscarinic ACh receptor (mAChR) | dopamine release | donepezil | prepulse inhibition | galantamine | AChE inhibitor | Dopamine release | Galantamine | Donepezil | Apomorphine | Muscarinic ACh receptor (mAChR) | Prepulse inhibition | ACOUSTIC STARTLE REFLEX | FREELY MOVING RATS | PHARMACOLOGICAL CHARACTERIZATION | FRONTAL-CORTEX | CHOLINESTERASE-INHIBITORS | HIPPOCAMPAL ACETYLCHOLINE-RELEASE | EXTRACELLULAR ACETYLCHOLINE | IN-VIVO | MEDIAL PREFRONTAL CORTEX | PHARMACOLOGY & PHARMACY | REARING-INDUCED DEFICITS | Oxotremorine - pharmacology | Muscarinic Agonists - pharmacology | Male | Acetylcholine - metabolism | Nicotinic Antagonists - pharmacology | Galantamine - pharmacology | Behavior, Animal | Dose-Response Relationship, Drug | Drug Interactions | Prefrontal Cortex - drug effects | Apomorphine - pharmacology | Piperidines - pharmacology | Muscarinic Antagonists - pharmacology | Mecamylamine - pharmacology | Reflex, Startle - drug effects | Animals, Outbred Strains | Pirenzepine - pharmacology | Dopamine - metabolism | Inhibition (Psychology) | Dopamine Agonists - pharmacology | Acoustic Stimulation | Pirenzepine - analogs & derivatives | Benzazepines - pharmacology | Animals | Microdialysis | Cholinesterase Inhibitors - pharmacology | Dopamine Antagonists - pharmacology | Serotonin - metabolism | Prefrontal Cortex - metabolism | Mice | Indans - pharmacology | Receptors, Muscarinic - physiology | Index Medicus | Research Papers
Journal Article
Journal of General Physiology, ISSN 0022-1295, 09/2005, Volume 126, Issue 3, pp. 243 - 262
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 02/2017, Volume 58, Issue 2, pp. 892 - 900
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 03/2014, Volume 75, pp. 222 - 232
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 03/2013, Volume 304, Issue 6, pp. 428 - 437
We and others have shown that epithelial Na+ channels (ENaC) in alveolar type 2 (AT2) cells are activated by β2 agonists, steroid hormones, elevated oxygen... 
Single channel recording | Cholinergic receptor | Alveolar type 2 epithelial cell | Epithelial sodium channels | TRANSLOCATION | ACTIVATION | PHYSIOLOGY | ACETYLCHOLINE | PHOSPHATIDYLINOSITIDES | ENAC | FLUID CLEARANCE | RHOA | alveolar type 2 epithelial cell | epithelial sodium channels | single channel recording | NA+ CHANNEL | RESPIRATORY SYSTEM | IN-VIVO | cholinergic receptor | EXPRESSION | Oxotremorine - pharmacology | Muscarinic Agonists - pharmacology | Receptor, Muscarinic M3 - physiology | rhoA GTP-Binding Protein - metabolism | Epithelial Sodium Channels - metabolism | Receptor, Muscarinic M2 - physiology | rho-Associated Kinases - antagonists & inhibitors | Nicotine - pharmacology | rho-Associated Kinases - metabolism | Muscarinic Antagonists - pharmacology | Nicotinic Agonists - pharmacology | Amides - pharmacology | Membrane Potentials - drug effects | Receptor, Muscarinic M2 - metabolism | Epithelial Sodium Channel Agonists - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Receptor, Muscarinic M3 - metabolism | Rats | Atropine - pharmacology | Alveolar Epithelial Cells - metabolism | Alveolar Epithelial Cells - drug effects | Rats, Sprague-Dawley | Carbachol - pharmacology | Patch-Clamp Techniques | Animals | Mice | Pyridines - pharmacology | Enzyme Activation | Alveolar Epithelial Cells - physiology | Sodium channels | Receptors | Epithelial cells | Physiological aspects | Acetylcholine | Properties | Epithelium
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 01/2009, Volume 108, Issue 2, pp. 437 - 449
The ability of G protein‐coupled receptors to regulate osmosensitive uptake of the organic osmolyte, taurine, into human SH‐SY5Y neuroblastoma cells has been... 
taurine transporter | volume‐sensitive organic osmolyte and anion channel | hyponatremia | volume regulation | muscarinic cholinergic receptor | organic osmolytes | Muscarinic cholinergic receptor | Hyponatremia | Organic osmolytes | Volume regulation | Taurine transporter | Volume-sensitive organic osmolyte and anion channel | MOUSE-BRAIN | volume-sensitive organic osmolyte and anion channel | CHLORIDE CHANNELS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYPO-OSMOLARITY | PROTEIN-COUPLED RECEPTORS | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | CEREBELLAR GRANULE CELLS | VOLUME-SENSITIVE EFFLUX | AMINO-ACIDS | CHOLINERGIC-RECEPTORS | Tritium - pharmacology | Calcium - metabolism | Muscarinic Agonists - pharmacology | Humans | Neuroblastoma | Dose-Response Relationship, Drug | Osmolar Concentration | Thrombin - pharmacology | Tritium - metabolism | Oxotremorine - analogs & derivatives | Lysophospholipids - pharmacology | Biological Transport - drug effects | Alanine - pharmacology | Taurine - analogs & derivatives | Guanidine - pharmacology | Enzyme Inhibitors - pharmacology | Saline Solution, Hypertonic - pharmacology | Antioxidants - pharmacology | Cyclopentanes - pharmacology | Sphingosine - pharmacology | Sphingosine - analogs & derivatives | Cell Line, Tumor | Thapsigargin - pharmacology | Taurine - pharmacology | Taurine - metabolism | Indans - pharmacology | Receptors, Muscarinic - physiology | Proteins | Neurology | Biochemistry | Cellular biology | Sodium
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2000, Volume 20, Issue 5, pp. 1710 - 1721
Channels from KCNQ2 and KCNQ3 genes have been suggested to underlie the neuronal M-type K(+) current. The M current is modulated by muscarinic agonists via... 
M current | channel | Patch clamp | G-protein | Muscarinic receptor | Calcium | INTRACELLULAR CA2 | RECEPTOR SUBTYPES | CA2+ CHANNELS | CALCIUM CHANNELS | RAT SYMPATHETIC NEURONS | BETA-GAMMA-SUBUNITS | IDIOPATHIC EPILEPSY | N-ETHYLMALEIMIDE | NEUROSCIENCES | PROTEIN-KINASES | POTASSIUM CHANNEL | Oxotremorine - pharmacology | Potassium Channels, Voltage-Gated | Tetraethylammonium - pharmacology | Calcium - metabolism | Muscarinic Agonists - pharmacology | Calcium Signaling - physiology | Humans | Cytoplasm - metabolism | Male | Neurons - cytology | Receptors, Muscarinic - metabolism | Potassium Channels - metabolism | KCNQ3 Potassium Channel | Muscarinic Antagonists - pharmacology | Gene Expression - physiology | KCNQ2 Potassium Channel | Cloning, Molecular | Egtazic Acid - analogs & derivatives | Neurons - physiology | Ethylmaleimide - pharmacology | Receptors, Muscarinic - genetics | Neurons - chemistry | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Atropine - pharmacology | Chelating Agents - pharmacology | Superior Cervical Ganglion - cytology | Rats, Sprague-Dawley | Anthracenes - pharmacology | Potassium Channels - genetics | Patch-Clamp Techniques | Animals | Egtazic Acid - pharmacology | Calcium Signaling - drug effects | Thapsigargin - pharmacology | Second Messenger Systems - physiology | Staurosporine - pharmacology | GTP-Binding Proteins - metabolism | K+ channel | ARTICLE | patch clamp | calcium | muscarinic receptor
Journal Article
Psychopharmacology, ISSN 0033-3158, 2/2017, Volume 234, Issue 4, pp. 559 - 573
In depressive disorders, one of the mechanisms proposed for antidepressant drugs is the enhancement of synaptic plasticity in the hippocampus and cerebral... 
Forced swimming test | Neurosciences | Cerebral cortex | Novelty suppressed feeding test | mAChR | Behavioral test | Biomedicine | Chronic restraint stress | Elevated plus maze test | Anxiety | Pharmacology/Toxicology | Neurotrophins | Psychiatry | ALTERS DENDRITIC MORPHOLOGY | MESSENGER-RNA EXPRESSION | PSYCHIATRY | FIBROBLAST-GROWTH-FACTOR | MAJOR DEPRESSION | BIPOLAR DISORDER | ANTIDEPRESSANT DRUGS | NEUROSCIENCES | NEUROTROPHIC FACTOR EXPRESSION | MOOD DISORDERS | FACTOR SYSTEM | PHARMACOLOGY & PHARMACY | Oxotremorine - pharmacology | Rats, Wistar | Muscarinic Agonists - pharmacology | Muscarinic Agonists - therapeutic use | Anti-Anxiety Agents - pharmacology | Rats | Male | Anxiety - drug therapy | Hippocampus - drug effects | Oxotremorine - therapeutic use | Hippocampus - metabolism | Animals | Prefrontal Cortex - drug effects | Stress, Psychological - metabolism | Prefrontal Cortex - metabolism | Fibroblast Growth Factor 2 - metabolism | Brain-Derived Neurotrophic Factor - metabolism | Neurons - metabolism | Neurons - drug effects | Anxiety - metabolism | Pharmacology, Experimental | Brain-derived neurotrophic factor | Psychopharmacology | Physiological aspects | Fibroblast growth factors | Research | Muscarinic receptors | Health aspects | Parasympathomimetic agents | Antianxiety agents | Studies | Brain research | Anxieties | Analysis | Behavior | Stress
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/1998, Volume 18, Issue 13, pp. 4946 - 4952
Rat pinealocytes, melatonin-secreting endocrine cells, contain peripheral glutaminergic systems. L-Glutamate is a negative regulator of melatonin synthesis... 
Nicotinic acetylcholine receptor (nAchR) | Pinealocyte | Parasympathetic neuron | Pineal gland | Microvesicle (synaptic-like microvesicle) | Serotonin N-acetyltransferase | L-type Ca | channel | Acetylcholine | Melatonin synthesis | Exocytosis | Glutamate | MECHANISM | pinealocyte | nicotinic acetylcholine receptor (nAchR) | serotonin N-acetyltransferase | MICROVESICLES | microvesicle (synaptic-like microvesicle) | pineal gland | AGONISTS | NEUROSCIENCES | L-type Ca2+ channel | melatonin synthesis | PERFORMANCE LIQUID-CHROMATOGRAPHY | ELECTROCHEMICAL DETECTION | CHANNEL | CALCIUM | exocytosis | acetylcholine | glutamate | GLAND | MODULATION | parasympathetic neuron | Oxotremorine - pharmacology | Synaptic Vesicles - metabolism | Arylamine N-Acetyltransferase - metabolism | Rats, Wistar | Calcium - metabolism | Muscarinic Agonists - pharmacology | Calcium Channels, L-Type | Nicotinic Antagonists - pharmacology | Exocytosis - drug effects | Nicotine - pharmacology | Diltiazem - pharmacology | Scopolamine Hydrobromide - pharmacology | Calcium Channels - physiology | Tubocurarine - pharmacology | Muscarinic Antagonists - pharmacology | Parasympathetic Nervous System - physiology | Pineal Gland - cytology | Nicotinic Agonists - pharmacology | Nifedipine - pharmacology | Pineal Gland - enzymology | Calcium - pharmacology | Acetylcholine - pharmacology | Cells, Cultured | 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester - pharmacology | Rats | Atropine - pharmacology | Nitrendipine - pharmacology | Pineal Gland - drug effects | Calcium Channel Blockers - pharmacology | Carbachol - pharmacology | Animals | Receptors, Nicotinic - physiology | Muscarine - pharmacology | Synaptic Vesicles - drug effects | Calcium Channel Agonists - pharmacology | Melatonin - biosynthesis | Glutamic Acid - metabolism | Bungarotoxins - pharmacology
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 10/2009, Volume 37, Issue 10, pp. 2028 - 2036
Journal Article
The Journal of Physiology, ISSN 0022-3751, 10/2004, Volume 560, Issue 1, pp. 77 - 88
Journal Article