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1. Full Text Oxidative stress in psoriasis and potential therapeutic use of antioxidants
by Lin, Xiran and Huang, Tian
Free Radical Research, ISSN 1071-5762, 06/2016, Volume 50, Issue 6, pp. 585 - 595
The pathophysiology of psoriasis is complex and dynamic. Recently, the involvement of oxidative stress in the pathogenesis of psoriasis has been proposed.... 
Angiogenesis | dendritic cells | inflammatory signaling pathways | keratinocyte | reactive oxygen species | dimethyl fumarate | T cells | ACTIVATED PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NECROSIS-FACTOR-ALPHA | MALONDIALDEHYDE LEVELS | REGULATED KINASE | CHRONIC PLAQUE PSORIASIS | REDOX REGULATION | SKIN | NF-KAPPA-B | T-CELLS | Antioxidants - therapeutic use | Psoriasis - physiopathology | Humans | Oxidative Stress - immunology | Psoriasis - therapy
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2. Full Text Disulfiram, an old drug with new potential therapeutic uses for human hematological malignancies
by Conticello, Concetta and Martinetti, Daniela and Adamo, Luana and Buccheri, Simona and Giuffrida, Raffaella and Parrinello, Nunziatina and Lombardo, Laura and Anastasi, Gabriele and Amato, Gabriella and Cavalli, Maide and Chiarenza, Annalisa and De Maria, Ruggero and Giustolisi, Rosario and Gulisano, Massimo and Di Raimondo, Francesco
International Journal of Cancer, ISSN 0020-7136, 11/2012, Volume 131, Issue 9, pp. 2197 - 2203
Disulfiram (DSF) is an aldehyde dehydrogenase inhibitor currently used for the treatment of alcoholism. Here, we show that multiple myeloma (MM) cell lines and... 
apoptosis | multiple myeloma | disulfiram | mitochondria | acute leukemia | CANCER-CELLS | OXIDATIVE STRESS | PROTEIN | ANTIALCOHOLISM DRUG | CELL-SURVIVAL | PROTEASOME ACTIVITY | INHIBITION | ONCOLOGY | PATHWAY | GROWTH | Free Radical Scavengers - pharmacology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Leukemia, Myeloid, Acute - metabolism | Antineoplastic Agents - therapeutic use | Mitochondrial Membranes - drug effects | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Multiple Myeloma - drug therapy | Caspases - biosynthesis | Leukemia, Myeloid, Acute - drug therapy | Antineoplastic Agents - pharmacology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Membrane Potentials - drug effects | Leukemia, Myeloid, Acute - pathology | Copper - pharmacology | Enzyme Inhibitors - pharmacology | Multiple Myeloma - metabolism | Disulfiram - therapeutic use | Multiple Myeloma - pathology | Acetylcysteine - pharmacology | Cell Line, Tumor | Oxidative Stress - drug effects | Disulfiram - pharmacology | Antioxidants | Usage | Chemotherapy | Alcoholism | Leukemia | Acetylcysteine | Disulfiram | Mitochondrial DNA | Aldehydes | Health aspects | Cells | Cancer | Copper | Blood
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3. Experiments with oxygen on disease
by Todd, James
1916, viii, 225 p. illus., diagrs. (part fold.)
Oxygen | Therapeutic use
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4. Full Text Anti-oxidants for therapeutic use: Why are only a few drugs in clinical use?
by Suzuki, Keiichiro
Advanced Drug Delivery Reviews, ISSN 0169-409X, 2009, Volume 61, Issue 4, pp. 287 - 289
It is well known that ROS are involved in a wide spectrum of diseases. In spite of this fact, only a few drugs are currently in use in clinical settings:... 
Flavonoids | Ascorbic acid | Superoxide dismutase | Ebselen | Edaravone | Tocopherol | Glutathione | N-acetylcysteine | PHARMACOLOGY & PHARMACY | Antioxidants - therapeutic use | Animals | Reactive Oxygen Species - metabolism | Antioxidants - chemistry | Humans | Oxidative Stress - physiology | Antioxidants - pharmacology | Clinical Trials as Topic - methods | Oxidative Stress - drug effects
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5. Full Text Biotechnological, nutritional and therapeutic uses of Pleurotus spp. (Oyster mushroom) related with its chemical composition: A review on the past decade findings
by Corrêa, Rúbia Carvalho Gomes and Brugnari, Tatiane and Bracht, Adelar and Peralta, Rosane Marina and Ferreira, Isabel C.F.R
Trends in Food Science & Technology, ISSN 0924-2244, 04/2016, Volume 50, pp. 103 - 117
The particular characteristics of growth and development of mushrooms in nature result in the accumulation of a variety of secondary metabolites, several of... 
β-glucan | Functional foods | Mushrooms | Natural products | Submerged cultures | POSTHARVEST QUALITY | ANTIINFLAMMATORY ACTIVITY | beta-glucan | LOW-OXYGEN STORAGE | FOOD SCIENCE & TECHNOLOGY | GENUS PLEUROTUS | SAJOR-CAJU | ANTIOXIDANT PROPERTIES | SUBMERGED FERMENTATION | SOLID-STATE FERMENTATION | HIGH-CARBON DIOXIDE | ENZYMES PRODUCTION | Health aspects | Usage | Plant metabolites | Demand | Drugs | Surgical implants | Accessibility | Searching | Biological | Arrays
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6. Full Text Isolation and characterization of np-pol nonapeptide for possible therapeutic use in Parkinson's disease
by Lemieszewska, Marta and Polanowski, Antoni and Wilusz, Tadeusz and Sokołowska, Agata and Zambrowicz, Aleksandra and Mikołajewicz, Katarzyna and Macała, Józefa and Rymaszewska, Joanna and Zabłocka, Agnieszka
Oxidative Medicine and Cellular Longevity, ISSN 1942-0900, 2018, Volume 2018, p. 3760124
Colostrum and milk are the initial mammalian nourishment and rich reservoir of essential nutrients for newborn development. Bioactive peptides isolated from... 
ANTIOXIDANT ACTIVITY | PATHWAYS | COMPLEX | NATURAL-PRODUCTS | PROLINE-RICH POLYPEPTIDE | 6-HYDROXYDOPAMINE | PC12 CELLS | OVINE COLOSTRUM | NEUROTOXICITY | CYTOTOXICITY | CELL BIOLOGY | Adrenal Gland Neoplasms - drug therapy | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Parkinson Disease - drug therapy | Extracellular Signal-Regulated MAP Kinases - metabolism | PC12 Cells | Neuroprotective Agents - pharmacology | Cattle | Pheochromocytoma - pathology | Female | Parkinson Disease - metabolism | Oligopeptides - chemistry | Adrenal Gland Neoplasms - pathology | Colostrum - chemistry | Pheochromocytoma - metabolism | Amino Acid Sequence | Parkinson Disease - pathology | Neuroprotective Agents - chemistry | Rats | Oligopeptides - isolation & purification | Pheochromocytoma - drug therapy | Animals | Neuroprotective Agents - isolation & purification | Adrenal Gland Neoplasms - metabolism | Sheep | Oligopeptides - pharmacology
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7. Full Text Treatment of children with pulmonary hypertension. Expert consensus statement on the diagnosis and treatment of paediatric pulmonary hypertension. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK
by Hansmann, Georg and Apitz, Christian
Heart, ISSN 1355-6037, 05/2016, Volume 102, Issue Suppl 2, pp. ii67 - ii85
Treatment of children and adults with pulmonary hypertension (PH) with or without cardiac dysfunction has improved in the last two decades. The so-called... 
5 INHIBITOR THERAPY | ADD-ON THERAPY | CARDIAC & CARDIOVASCULAR SYSTEMS | CONGENITAL HEART-DISEASE | ARTERIAL-HYPERTENSION | DOUBLE-BLIND | TRANSCATHETER POTTS SHUNT | RANDOMIZED CONTROLLED-TRIAL | PLACEBO-CONTROLLED TRIAL | CONTINUOUS INTRAVENOUS EPOPROSTENOL | ENDOTHELIN RECEPTOR ANTAGONIST | Prostaglandins - therapeutic use | Vasodilator Agents - therapeutic use | Humans | Calcium Channel Blockers - therapeutic use | Anticoagulants - therapeutic use | Nitric Oxide - therapeutic use | Oxygen Inhalation Therapy | Consensus | Endothelium-Dependent Relaxing Factors - therapeutic use | Hypertension, Pulmonary - therapy | Mineralocorticoid Receptor Antagonists - therapeutic use | Warfarin - therapeutic use | Adolescent | Diuretics - therapeutic use | Aspirin - therapeutic use | Phosphodiesterase 5 Inhibitors - therapeutic use | Contraceptives, Oral - therapeutic use | Endothelin Receptor Antagonists - therapeutic use | Platelet Aggregation Inhibitors - therapeutic use | Child
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8. Mechanisms of Esophageal Protection, Gastroprotection and Ulcer Healing by Melatonin. Implications for the Therapeutic use of Melatonin in Gastroesophageal Reflux Disease (GERD) and Peptic Ulcer Disease
by Brzozowska, I and Strzalka, M and Drozdowicz, D and Konturek, SJ and Brzozowski, T
CURRENT PHARMACEUTICAL DESIGN, ISSN 1381-6128, 2014, Volume 20, Issue 30, pp. 4807 - 4815
Melatonin is a potent reactive oxygen metabolite scavenger and antioxidant that has been shown to influence many physiological functions of the... 
Melatonin | nitric oxide | MUCOSAL LESIONS | INDUCED GASTRIC-LESIONS | PINEAL-GLAND | L-tryptophan | sensory nerves | active oxygen metabolites | ENDOGENOUS MELATONIN | gastric blood flow | PERIPHERAL MELATONIN | PRECURSOR L-TRYPTOPHAN | NITRIC-OXIDE | GENE-EXPRESSION | prostaglandins | PHARMACOLOGY & PHARMACY | brain-gut axis | NOCTURNAL MELATONIN | ulcer healing | gastroprotection | Esophagus - drug effects | Gastroesophageal Reflux - drug therapy | Melatonin - pharmacology | Peptic Ulcer - drug therapy | Humans | Melatonin - therapeutic use
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9. Mechanisms of esophageal protection, gastroprotection and ulcer healing by mela-tonin. Implications for the therapeutic use of melatonin in gastroesophageal reflux disease (gerd) and peptic ulcer disease
by Brzozowska, Iwona and Strzalka, Malgorzata and Drozdowicz, Danuta and Konturek, Stanislaw J and Brzozowski, Tomasz
Current Pharmaceutical Design, ISSN 1381-6128, 2014, Volume 20, Issue 30, pp. 4807 - 4815
Gastroprotection | Melatonin | Prostaglandins | Ulcer healing | Nitric oxide | Sensory nerves | Gastric blood flow | L-tryptophan | Brain-gut axis | Active oxygen metabolites
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10. Full Text Redox nanoparticle therapeutics to cancer — increase in therapeutic effect of doxorubicin, suppressing its adverse effect
by Yoshitomi, Toru and Ozaki, Yuki and Thangavel, Sindhu and Nagasaki, Yukio
Journal of Controlled Release, ISSN 0168-3659, 11/2013, Volume 172, Issue 1, pp. 137 - 143
The ultimate goal of cancer chemotherapy is to achieve a cure without causing any adverse effects. We have developed a pH-sensitive redox nanoparticle (RNP ),... 
Reactive oxygen species | Transcriptional factor | Cancer chemotherapy | Doxorubicin | Nitroxide radical | pH-responsive polymeric micelle | CELLS | OXIDATIVE STRESS | MITOCHONDRIAL-FUNCTION | DRUG-RESISTANCE | ANTITUMOR-ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | BREAST-CANCER | IN-VIVO | PHARMACOLOGY & PHARMACY | RADICAL-CONTAINING NANOPARTICLES | NF-KAPPA-B | Free Radical Scavengers - pharmacology | Neoplasms - metabolism | Doxorubicin - therapeutic use | Reactive Oxygen Species - metabolism | Antibiotics, Antineoplastic - pharmacology | Nanoparticles - chemistry | Humans | NF-kappa B - immunology | Antibiotics, Antineoplastic - adverse effects | Delayed-Action Preparations - chemistry | Inflammation - drug therapy | Free Radical Scavengers - therapeutic use | Nitrogen Oxides - therapeutic use | Oxidation-Reduction | Free Radical Scavengers - administration & dosage | Nitrogen Oxides - administration & dosage | Inflammation - immunology | Neoplasms - drug therapy | Drug Synergism | Animals | Antibiotics, Antineoplastic - therapeutic use | Neoplasms - immunology | Nitrogen Oxides - pharmacology | Mice | Mice, Inbred BALB C | Doxorubicin - adverse effects | Doxorubicin - pharmacology | Complications and side effects | Anthracyclines | Chemotherapy | Cancer | Creatine kinase | College graduates | Creatine | Adjuvants
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11. Oxygen insufflation in periodontal diseases
by Box, Harold Keith, 1890-1956
1955, American lecture series, publication no. 237. American lectures in dentistry, xi, 94 p. illus.
Oxygen | Teeth | Therapeutic use | Diseases
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12. Full Text Molecular Mechanisms of Action and Therapeutic Uses of Pharmacological Inhibitors of HIF–Prolyl 4-Hydroxylases for Treatment of Ischemic Diseases
by Selvaraju, Vaithinathan and Parinandi, Narasimham L and Adluri, Ram Sudheer and Goldman, Joshua W and Hussain, Naveed and Sanchez, Juan A and Maulik, Nilanjana
Antioxidants & Redox Signaling, ISSN 1523-0864, 06/2014, Volume 20, Issue 16, pp. 2631 - 2665
Significance: In this review, we have discussed the efficacy and effect of small molecules that act as prolyl hydroxylase domain inhibitors (PHDIs). The use of... 
Review Article | RETINAL NEOVASCULARIZATION | HYPOXIA-INDUCIBLE FACTOR | HYDROXYLASE DOMAIN PROTEIN-2 | INFLAMMATORY-BOWEL-DISEASE | OXYGEN-INDUCED RETINOPATHY | BIOCHEMISTRY & MOLECULAR BIOLOGY | REPERFUSION INJURY | ENDOCRINOLOGY & METABOLISM | DISULFIDE-ISOMERASE SUBUNIT | FACTOR-I | MITOCHONDRIAL COMPLEX-III | GROWTH-FACTOR EXPRESSION | Prolyl-Hydroxylase Inhibitors - chemistry | Myocardial Ischemia - metabolism | Hypoxia-Inducible Factor-Proline Dioxygenases - metabolism | Prolyl-Hydroxylase Inhibitors - pharmacology | Humans | Hypoxia-Inducible Factor-Proline Dioxygenases - antagonists & inhibitors | Molecular Structure | Myocardial Ischemia - enzymology | Structure-Activity Relationship | Myocardial Ischemia - drug therapy | Review
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13. Full Text Therapeutic uses of antioxidant liposomes
by Stone, William L and Smith, Milton
Molecular Biotechnology, ISSN 1073-6085, 7/2004, Volume 27, Issue 3, pp. 217 - 230
This review will focus on the therapeutic uses of antioxidant liposomes. Antioxidant liposomes have a unique ability to deliver both lipid- and water-soluble... 
Antioxidants | Neurology | Neurosciences | Biomedicine | liposomes | respiratory distress syndrome pulmonary infections | γ-tocopherol | α-tocopherol | Liposomes | Respiratory distress syndrome pulmonary infections | OXIDATIVE STRESS | VITAMIN-E | antioxidants | BIOCHEMISTRY & MOLECULAR BIOLOGY | alpha-tocopherol | ACUTE LUNG INJURY | INDUCED LIPID-PEROXIDATION | TRANS-RETINOIC ACID | PULMONARY OXYGEN-TOXICITY | FREE-RADICALS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | LONG CIRCULATING LIPOSOMES | ALPHA-TOCOPHEROL LIPOSOMES | gamma-tocopherol | ENTRAPPED SUPEROXIDE-DISMUTASE | Animals | Liposomes - administration & dosage | Enzymes - administration & dosage | Humans | Antioxidants - administration & dosage | Coated Materials, Biocompatible - administration & dosage | Drug Carriers - administration & dosage | Oxidative Stress - drug effects | Lung Diseases - drug therapy | Drug Delivery Systems - methods | Delayed-Action Preparations - administration & dosage | Neoplasms - drug therapy | Health aspects | Usage | Respiratory distress syndrome | Biological & chemical weapons
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14. Full Text Spanish Guidelines for Management of Chronic Obstructive Pulmonary Disease (GesEPOC) 2017. Pharmacological Treatment of Stable Phase
by Miravitlles, Marc and Soler-Cataluña, Juan José and Calle, Myriam and Molina, Jesús and Almagro, Pere and Quintano, José Antonio and Trigueros, Juan Antonio and Cosío, Borja G and Casanova, Ciro and Antonio Riesco, Juan and Simonet, Pere and Rigau, David and Soriano, Joan B and Ancochea, Julio
Archivos de Bronconeumologia, ISSN 0300-2896, 06/2017, Volume 53, Issue 6, pp. 324 - 335
The clinical presentation of chronic obstructive pulmonary disease (COPD) varies widely, so treatment must be tailored according to the level of risk and... 
Phenotypes | Chronic obstructive pulmonary disease | Treatment | Guidelines | Bronchodilator Agents - therapeutic use | Pulmonary Medicine - standards | Phosphodiesterase Inhibitors - therapeutic use | Pulmonary Disease, Chronic Obstructive - diagnosis | Pulmonary Emphysema - complications | Risk Assessment | Adrenal Cortex Hormones - therapeutic use | Diagnostic Techniques, Respiratory System - standards | Oxygen Inhalation Therapy | Spain | Anti-Bacterial Agents - therapeutic use | Antioxidants - therapeutic use | Phenotype | Pulmonary Disease, Chronic Obstructive - therapy | alpha 1-Antitrypsin - therapeutic use | Societies, Medical | Expectorants - therapeutic use | Pulmonary Medicine - organization & administration | Bronchitis - complications | Disease Management | Pulmonary Disease, Chronic Obstructive - drug therapy
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