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1. Full Text Antiviral oxysterols are present in human milk at diverse stages of lactation
by Civra, Andrea and Leoni, Valerio and Caccia, Claudio and Sottemano, Stefano and Tonetto, Paola and Coscia, Alessandra and Peila, Chiara and Moro, Guido E and Gaglioti, Pietro and Bertino, Enrico and Poli, Giuseppe and Lembo, David
The Journal of steroid biochemistry and molecular biology, ISSN 0960-0760, 10/2019, Volume 193, pp. 105424 - 105424
Antiviral | Colostrum | Maternal milk | Rotavirus | Oxysterols | Rhinovirus | Oxysterols - analysis | Rhinovirus - drug effects | Cell Line | Antiviral Agents - pharmacology | Chlorocebus aethiops | Lactation | Antiviral Agents - blood | Humans | Milk, Human - chemistry | Oxysterols - pharmacology | Antiviral Agents - analysis | Animals | Oxysterols - blood | Adult | Female | Rotavirus - drug effects | Colostrum - chemistry | Enzymatic synthesis | Breastfeeding & lactation | Immune response | Baby foods | Mass spectroscopy | Breast feeding | Cholesterol | Gas chromatography | Sterols | Cattle | Antiviral activity | Oxidation | Breast milk | Index Medicus
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2. Full Text Free oxysterols and bile acids including conjugates - Simultaneous quantification in human plasma and cerebrospinal fluid by liquid chromatography-tandem mass spectrometry
by Reinicke, Madlen and Schröter, Jenny and Müller-Klieser, Daniel and Helmschrodt, Christin and Ceglarek, Uta
Analytica chimica acta, ISSN 0003-2670, 12/2018, Volume 1037, pp. 245 - 255
Validation | Free oxysterols | Footnote | LIFE-Adult | Targeted metabolomics | Pre-analytics | Free bile acids | Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology | Tandem Mass Spectrometry | Bile Acids and Salts - blood | Humans | Bile Acids and Salts - chemistry | Oxysterols - chemistry | Solid Phase Extraction | Chromatography, Liquid | Oxysterols - blood | Bile Acids and Salts - metabolism | Bile Acids and Salts - cerebrospinal fluid | Oxysterols - metabolism | Oxysterols - cerebrospinal fluid | Liquid chromatography | Precipitation (Meteorology) | Metabolites | Mass spectrometry | Analysis | Deoxycholic acid | Deuterium | Plasma | Additives | Lithium | Cerebrospinal fluid | Cholic acid | Ursodeoxycholic acid | Blood plasma | Proteins | Sample preparation | Blood-brain barrier | Ethylenediaminetetraacetic acids | Disturbance | Lipid metabolism | Solid phases | Stability tests | Spectroscopy | Taurocholic acid | Anticoagulants | Bile acids | Chemical precipitation | Mass spectroscopy | Stability analysis | Metabolism | Patients | Cholesterol | Esterification | Citric acid | Acids | Ionization | Heparin | Chenodeoxycholic acid | Edetic acid | Index Medicus
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3. A comprehensive review on oxysterols and related diseases
by Samadi, Afshin and Sabuncuoglu, Suna and Samadi, Mahshid and Isikhan, Selen Yilmaz and Chirumbolo, Salvatore and Peana, Massimiliano and Lay, Incilay and Yalcinkaya, Ahmet and Bjørklund, Geir
Current medicinal chemistry, ISSN 0929-8673, 2020, Volume 28, Issue 1, pp. 110 - 136
Molecular targets | Cholesterol excretion pathways | Disease | Pathophysiology | Oxysterol | Hydroxycholesterol | Cholesterol | Oxidation-Reduction | Humans | Oxysterols - metabolism | Oxysterols - chemistry
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4. Full Text New methods for analysis of oxysterols and related compounds by LC–MS
by Griffiths, William J and Abdel-Khalik, Jonas and Crick, Peter J and Yutuc, Eylan and Wang, Yuqin
The Journal of steroid biochemistry and molecular biology, ISSN 0960-0760, 09/2016, Volume 162, pp. 4 - 26
Derivatisation | Hydroxycholesterol | Epoxycholesterol | Liquid chromatography | Mass spectrometry | Cholesterol | Sterol | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Oxysterols - analysis | Animals | Validation Studies as Topic | Humans | Oxysterols - blood | Cholesterol - metabolism | Chromatography, Liquid - methods | Mass Spectrometry - methods | Oxysterols - metabolism | Oxysterols - cerebrospinal fluid | Medical colleges | Nervous system diseases | Multiple sclerosis | Fatty acids | Deoxycholic acid | Synthesis | Atherosclerosis | Physiological aspects | Binding proteins | Alzheimer's disease | Methods | Steroid hormones | Protein binding | Index Medicus
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5. Full Text Oxysterols: An emerging class of broad spectrum antiviral effectors
by Lembo, David and Cagno, Valeria and Civra, Andrea and Poli, Giuseppe
Molecular aspects of medicine, ISSN 0098-2997, 06/2016, Volume 49, pp. 23 - 30
Enveloped virus | Oxysterols | 27-Hydroxycholesterol | Non-enveloped viruses | Antiviral | Innate immunity | 25-Hydroxycholesterol | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Virus Replication - drug effects | Antiviral Agents - pharmacology | Reactive Oxygen Species - metabolism | Viruses - genetics | Immunity, Innate - drug effects | Oxidation-Reduction | Virus Replication - genetics | Humans | Viruses - metabolism | Viruses - drug effects | Antiviral Agents - metabolism | Oxysterols - pharmacology | Host-Pathogen Interactions - immunology | Animals | Antiviral Agents - chemistry | Oxysterols - chemistry | Oxysterols - metabolism | Antiviral agents | Enzymes | Hydroxides | Liver | Index Medicus
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6. Full Text Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation
by Testa, Gabriella and Staurenghi, Erica and Zerbinati, Chiara and Gargiulo, Simona and Iuliano, Luigi and Giaccone, Giorgio and Fantò, Fausto and Poli, Giuseppe and Leonarduzzi, Gabriella and Gamba, Paola
Redox biology, ISSN 2213-2317, 12/2016, Volume 10, Issue C, pp. 24 - 33
Sirtuin-1 | Inflammation | Alzheimer's disease | Cholesterol metabolism | Oxysterols | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Oxidative Stress | Humans | Gene Expression Regulation | Cholesterol 24-Hydroxylase - genetics | Sirtuin 1 - genetics | Disease Progression | Alzheimer Disease - pathology | Brain - metabolism | Cholestanetriol 26-Monooxygenase - genetics | Matrix Metalloproteinase 9 - genetics | Alzheimer Disease - metabolism | Brain - pathology | Alzheimer Disease - genetics | Oxysterols - metabolism | Index Medicus
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7. Full Text Fluoro analogs of bioactive oxy-sterols: Synthesis of an EBI2 agonist with enhanced metabolic stability
by Deng, Xiaohu and Sun, Siquan and Wu, Jiejun and Kuei, Chester and Joseph, Victory and Liu, Changlu and Mani, Neelakandha S
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 10/2016, Volume 26, Issue 20, pp. 4888 - 4891
EBI2 agonist | Immune response | GPR 183 | Fluoro oxysterol | Epstein–Barr virus | Oxysterols | Cell Line | Animals | Receptors, G-Protein-Coupled - metabolism | Humans | Herpesvirus 4, Human - drug effects | Oxysterols - chemistry | Oxysterols - chemical synthesis | Herpesvirus 4, Human - metabolism | Oxysterols - pharmacology | Virus diseases | Sterols | Health aspects | Index Medicus
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8. Full Text Olive oil polyphenols reduce oxysterols -induced redox imbalance and pro-inflammatory response in intestinal cells
by Serra, Gessica and Incani, Alessandra and Serreli, Gabriele and Porru, Laura and Melis, M.Paola and Tuberoso, Carlo I.G and Rossin, Daniela and Biasi, Fiorella and Deiana, Monica
Redox biology, ISSN 2213-2317, 07/2018, Volume 17, pp. 348 - 354
Polyphenols | Oxidative stress | Inflammation | Caco-2 cells | Olive oil | Oxysterols | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Caco-2 Cells | Intestines - drug effects | Inflammation - pathology | Nitric Oxide - biosynthesis | Intestinal Mucosa - metabolism | Reactive Oxygen Species - metabolism | Interleukin-8 - biosynthesis | Humans | Polyphenols - pharmacology | Antioxidants - pharmacology | Inflammation - metabolism | Olive Oil - pharmacology | NF-kappa B - genetics | Signal Transduction - drug effects | Oxidation-Reduction - drug effects | Inflammation - genetics | Interleukin-6 - biosynthesis | Inflammation - prevention & control | Oxidative Stress - drug effects | Oxysterols - metabolism | Index Medicus
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9. LC/MS/MS profiling of tissue oxysterols and its application in dextran sodium sulphate induced mouse colitis models
by Wu, Jiejun and Eric McDuffie, J and Song, Jiao and Harris, Michael C and Raymond, Holly and Chen, Yafei and Nguyen, Leslie and Nguyen, Steven and Kanerva, Justin and McAllister, Heather M and Deng, Xiaohu and Mani, Neelakandha and Liu, Changlu and Sun, Siquan
Current topics in medicinal chemistry, ISSN 1568-0266, 09/2017, Volume 17, Issue 24, pp. 2781 - 2790
Dihydroxycholesterols | Mouse colitis biomarker | Oxysterol quantification | Oxysterol separation | Oxysterol analysis | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Dextran Sulfate | Colon - pathology | Mice, Inbred C57BL | Colon - chemistry | Oxysterols - isolation & purification | Tandem Mass Spectrometry | Animals | Colitis - chemically induced | Oxysterols - chemistry | Chromatography, Liquid | Female | Mice | Disease Models, Animal | Animal models | Workflow | Sodium sulfates | Sulfates | Dextran | Inflammatory bowel disease | Dilution | Sodium | Sodium sulfate | Animal tissues | Colon | Colitis
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10. Full Text Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling
by Huang, Pengxiang and Nedelcu, Daniel and Watanabe, Miyako and Jao, Cindy and Kim, Youngchang and Liu, Jing and Salic, Adrian and Argonne National Lab. (ANL), Argonne, IL (United States)
Cell (Cambridge), ISSN 0092-8674, 08/2016, Volume 166, Issue 5, pp. 1176 - 1187.e14
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | NIH 3T3 Cells | Signal Transduction | Smoothened Receptor - agonists | Xenopus laevis | Hedgehog Proteins - metabolism | Crystallography, X-Ray | Smoothened Receptor - metabolism | Cholesterol - metabolism | Cholesterol - chemistry | Animals | Oxysterols - chemistry | Protein Binding | Protein Conformation | Mice | Oxysterols - metabolism | Smoothened Receptor - chemistry | Cysteine | Structure | Cells | Cholesterol | Crystals | Protein binding | Index Medicus | BASIC BIOLOGICAL SCIENCES
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